5 research outputs found
Intermediate filaments regulate tissue size and stiffness in the murine lens
- Author
- Publication venue
- Publication date
- 23/04/2020
- Field of study
PURPOSE. To define the contributions of the beaded filament (BF), a lens-specific intermediate filament (IF), to lens morphology and biomechanics. METHODS. Wild-type and congenic CP49 knockout (KO) mice were compared by using electrophysiological, biomechanical, and morphometric approaches, to determine changes that occurred because of the absence of this cytoskeletal structure. RESULTS. Electrophysiological assessment established that the fiber cells lacking the lens-specific IFs were indistinguishable from wild-type fiber cells. The CP49 KO mice exhibited lower stiffness, and an unexpected higher resilience than the wildtype lenses. The absence of these filaments resulted in lenses that were smaller, and exhibited a higher ratio of lens:lens nucleus size. Finally, lens shape differed as well, with the CP49 KO showing a higher ratio of axial:equatorial diameter. CONCLUSIONS. Previous work has shown that BFs are necessary in maintaining fiber cell and lens structural phenotypes with age, and that absence of these filaments results in a loss of lens clarity. This work demonstrates that several tissue-level properties that are critical to lens function are also dependent, at least in part, on the presence of these lens-specific IFs. (Invest Ophthalmol Vis Sci
Intermediate Filaments Regulate Tissue Size and Stiffness in the Murine Lens
- Author
- Publication venue
- Association for Research in Vision and Ophthalmology, Inc.
- Publication date
- 01/05/2011
- Field of study
To accomplish its functions, the lens must regulate many physical properties within very exacting tolerances, including size, shape, stiffness and resilience. In this article, the authors demonstrate that the lens-specific intermediate filaments (aka beaded filaments) are required for proper regulation of each of these properties, and thus play a central role in several lens-specific functions
Virtues, ecological momentary assessment/intervention and smartphone technology
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13Th International Conference On Conservative Management Of Spinal Deformities And First Joint Meeting Of The International Research Society On Spinal Deformities And The Society On Scoliosis Orthopaedic And Rehabilitation Treatment – Sosort-Irssd 2016 Meeting
- Author
- Adeeb Samer
- Adeeb Samer
- Ahmed El-Nasri
- Akbarnia Behrooz A.
- Aksoy Songul
- Andrusiewicz M.
- Aras Ozgen
- Aslanzadeh Fatemeh
- Aubin Carl-Eric
- Aubin Carl-Éric
- Aubin Carl-Éric
- Aubin-Fournier Jean-François
- Aulisa Angelo Gabriele
- Aulisa Angelo Gabriele
- Aulisa Angelo Gabriele
- Aulisa Lorenzo
- Aulisa Lorenzo
- Aulisa Lorenzo
- Ayhan Cigdem
- Bagheri Aria
- Bakarania Prachi
- Bakarania Prachi
- Bakarania Prachi
- Bakarania Prachi
- Banno Tomohiro
- Barch Soraya
- Barral Frédéric
- Barral Frédéric
- Barral Frédéric
- Barral Frédéric
- Barral Frédéric
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- Berdishevsky Hagit
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- Berdishevsky Hagit
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- Bernard Jean-Claude
- Bernard Jean-Claude
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- Berthonnaud Eric
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- Biswas Abhishek
- Black Jason
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- Bloom Zachary
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- Brignol Arnaud
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- Brink Rob C.
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- Brousseau Danica
- Burwell R. Geoffrey
- Bylski-Austrow Donita I.
- Bylski-Austrow Donita I.
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- Capodaglio Paolo
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- Chaloupka Amie
- Chan Andrew
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- Chen Huanxiong
- Chen Huanxiong
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- Cheng Jack C. Y.
- Cheng Jack C. Y.
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- Wall Eric J.
- Wang Bin
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- Watkins Elise
- Watkins Elise M.
- Webb Richard
- Weinstein Stuart L.
- Wong Judy Y. H.
- Wong Man Sang
- Wong Man-Sang
- Wu Tao
- Wu Xiao-Jun
- Xue Cindy
- Yakut Yavuz
- Yakut Yavuz
- Yamato Yu
- Yan Huang
- Yang Yan
- Yip Benjamin Hon Kei
- Yoshimachi Julie
- Yu Fiona W. P.
- Yu Fiona Wai Ping
- Yu Yang
- Zaina Fabio
- Zaina Fabio
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- Zaina Fabio
- Zhang Jiajun
- Zhang Jiajun
- Zhang Wen
- Zheng Rui
- Zheng Rui
- Zheng Yu
- Zhu Feng
- Zhu Weiguo
- Zhu Ze-zhang
- Zhu Zezhang
- Zhu Zezhang
- Zhu Zezhang
- Zhu Zezhang
- Zhu Zezhang
- Zhu Zezhang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
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13th International Conference on Conservative Management of Spinal Deformities and First Joint Meeting of the International Research Society on Spinal Deformities and the Society on Scoliosis Orthopaedic and Rehabilitation Treatment – SOSORT-IRSSD 2016 meeting: Banff, Canada. 25-28 May 2016
- Author
- Adeeb Samer
- Ahmed El-Nasri
- Akbarnia Behrooz A.
- Aksoy Songul
- Andrusiewicz M.
- Aras Ozgen
- Aslanzadeh Fatemeh
- Aubin Carl-Eric
- Aubin Carl-Éric
- Aubin-Fournier Jean-François
- Aulisa Angelo Gabriele
- Aulisa Lorenzo
- Ayhan Cigdem
- Bagheri Aria
- Bakarania Prachi
- Banno Tomohiro
- Barch Soraya
- Barral Frédéric
- Berdishevsky Hagit
- Bernard Jean-Claude
- Berthonnaud Eric
- Bettany-Saltikov Josette
- Biecek P.
- Biswas Abhishek
- Black Jason
- Bloom Zachary
- Boody Barrett
- Boyette Jeremy
- Bradley Michael
- Brignol Arnaud
- Brink Rob C.
- Brousseau Danica
- Burwell R. Geoffrey
- Bylski-Austrow Donita I.
- Caouette Christiane
- Capodaglio Paolo
- Caronni Antonio
- Castelein René M.
- Chakraborty Ashis Kumar
- Chaleat-Valayer Emmanuelle
- Chaloupka Amie
- Chan Andrew
- Chandrinos Michail
- Chatzistergos Panagiotis
- Chen He
- Chen Huanxiong
- Cheng Jack C. Y.
- Cheng Jack Chun Yiu
- Cheriet Farida
- Chockalingam Nachiappan
- Chorney Jill
- Chu Winnie C. W.
- Cobetto Nikita
- Cohen Larry
- Colo Dino
- Cook Tim
- Crandall Dennis G.
- Dang Yi-Ni
- Davenhill Ryan
- Davis Leigh
- de Mauroy Jean-Claude
- Deceuninck Julie
- Dennis Sarah
- Di Felice Francesca
- Dilek Burcu
- Dolan Lori A
- Donauer Andreas
- Donzelli Sabrina
- Doucet Chantal
- Drake Shawn
- Dritsa Despoina
- Duke Kajsa
- Dupuis Sarah
- Equbal Ameed
- Falciglia Francesco
- Fard Negar Behzadi
- Farmer Sybil
- Feinberg Nicholas
- Feldman Debbie Ehrmann
- Fortin Carole
- Galli Marco
- Garg Sumeet
- Gaweł Dominik
- Gelalis Ioannis D.
- Ghaneei Maliheh
- Gilday Sarah
- Glos David L.
- Glynn David
- Goh Tae Sik
- Gordano Marco
- Grant Alison
- Griffith James
- Grimes Kelly
- Grivas Theodoros B.
- Gundlach Benjamin
- Guo Jing
- Gur Gozde
- Guzzanti Vincenzo
- Głowka Paweł
- Han Xiao
- Hanchard Nigel
- Hanke Timothy A.
- Harasymczuk P.
- Hasegawa Tomohiko
- He Cheng-Qi
- Healy Aoife
- Hedden Douglas
- Hedden Douglas M.
- Hedden Douglass
- Hekal Waleed
- Hennes Axel
- Hill Doug
- Hill Douglas
- Hill Douglas L.
- Hoang Alith
- Holowka Mark
- Honeyman Cheryl
- Hong Kaitlin
- Hope Jennifer
- Hu Zongshan
- Hui Steve C. N.
- Hung Vivian W. Y.
- Hung Vivian Wing Yin
- Huynh Geraldine
- Hyman Joshua
- Igoumenou Vasilios G.
- Jain Viral V.
- Janusz P.
- Jasani Vinay
- Jevtić Nikola
- Jiang Jian
- Jin Mengran
- Kalyan Raman
- Karavidas Nikos
- Kasprzak Bartosz
- Kechagias Vasileios
- Kerslake Matthew
- Khasnabis Chapal
- Kim Donghyun
- Kim Junlae
- Knott Patrick
- Kobayashi Sarah
- Kobayashi Sho
- Kobayashi Yosuke
- Kotwicka M.
- Kotwicki T.
- Kotwicki Tomasz
- Krumdick Nathaniel D.
- Kumar Datta Tarit
- Labelle Hubert
- Lam Tsz Ping
- Laporte Catherine
- Larson Jill E.
- Larson Noelle
- Le Lawrence H.
- Lebel Andrea
- Lebel Victoria Ashley
- Lecante Cyril
- Lee Jung Sub
- Lee Wayne Yuk Wai
- Levey Lauren
- Lin Yangmin
- Lindgren Amelia
- Lindgren Amelia M.
- Liu Hao
- Liu Xue-Cheng
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- Liu Zhen
- Lou Edmond
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- Lukenchuk Leeann
- Lusini Monia
- MacIntosh Brian
- MacMahon Edward
- MacMahon John
- Mahood James K.
- Makhni Melvin C.
- Man Gene Chi Wai
- Man Gene Chiwai
- Man-Sang Wong
- Mao Sai-hu
- Mao Saihu
- Maragkoudakis Emmanouil G.
- Marcotte Louise
- Martinez Gregorio
- Maruyama Toru
- Mastantuoni Giuseppe
- Matsumoto Hiroko
- Matsuyama Yukihiro
- Maude Erika
- Mavrogenis Andreas F.
- Mazioti Christina
- Megaloikonomos Panayiotis D.
- Meyer Maximilian A.
- Michas Konstantinos
- Mihara Yuuki
- Minnella Salvatore
- Miron Marie-Claude
- Moez Elham Khodayari
- Morau Marc
- Moreau Marc
- Moreau Marc J.
- Morrison Pamela R.
- Morzyński Marek
- Murray Scott
- Nakao Yusuke
- Needham Robert
- Needham Robert A
- Negrini Alberto
- Negrini Stefano
- Neil Barbara
- Ng Bobby K. W.
- Ng Bobby Kin Wah
- North Paula
- Nowak Michał
- Oe Shin
- O’Hara Sara
- Panagopoulos Georgios N.
- Pancholi-Parekh Chintan A.
- Pantović Milan
- Papagelopoulos Panayiotis J.
- Pappas Evangelos
- Parent Eric
- Parent Eric C.
- Parent Stefan
- Persani Luca
- Pesenti Francesca
- Pialasse Jean-Philippe
- Pickering Marie-Eva
- Pietrosanu Matthew
- Pitruzzella Morena
- Pizzetti Paolo
- Poggio Martina
- Polli Nicoletta
- Pourret Sophie
- Qian Bang Ping
- Qian Bang-ping
- Qian Bangping
- Qin Ling
- Qiu Yong
- Raihan Hasan Md Arif
- Raso Jim
- Redford Emily
- Refshauge Kathryn
- Reynolds Joseph E.
- Rizza Robert
- Rosol Derek
- Rougelot Adrien
- Roye Benjamin
- Roye David
- Roye David P.
- Sanders James O.
- Sarwark John F.
- Sbihli Amy
- Schlösser Tom P. C.
- Schmidt Sheri
- Schreiber Sanja
- Schultz Lindsay
- Schwartz Mark
- Sciumè Luciana
- Selthafner Marissa
- Shannon Thomas
- Shi Benlong
- Shi Lin
- Shillingford Jamal
- Shin Jong Ki
- Shirley Matthew
- Simic Milena
- Simsek Engin
- Skaggs David L.
- Sloan Preston
- Smith John T.
- Son Seung Min
- Soultanis Konstantinos
- Southon Sarah
- Southon Sarah C.
- St-Jean Anissa
- Stikeleather Luke
- Stolze Lise
- Sturm Peter F.
- Sun Ning
- Sun Xu
- Swindell Hasani
- Tam Elisa M. S.
- Tam Elisa Man Shan
- Tarima Sergey
- Tassone Channing
- Thometz John
- Théroux Jean
- Tilburn Melissa
- Tobert Daniel
- Togawa Daisuke
- Touchette Julie
- Tsiavos Konstantinos
- Tsilimidos Gerasimos
- Tsui Ban
- Turgeon Isabelle
- Turland Abbie
- van Stralen Marijn
- Vincken Koen L.
- Vitale Michael
- Vitale Michael G.
- Vlasis Konstantinos
- Vo Quang N.
- Wall Eric J.
- Wang Bin
- Wang Tao
- Wang Xiaoyu
- Watkins Elise
- Watkins Elise M.
- Webb Richard
- Weinstein Stuart L.
- Wong Judy Y. H.
- Wong Man Sang
- Wong Man-Sang
- Wu Tao
- Wu Xiao-Jun
- Xue Cindy
- Yakut Yavuz
- Yamato Yu
- Yan Huang
- Yang Yan
- Yip Benjamin Hon Kei
- Yoshimachi Julie
- Yu Fiona W. P.
- Yu Fiona Wai Ping
- Yu Yang
- Zaina Fabio
- Zhang Jiajun
- Zhang Wen
- Zheng Rui
- Zheng Yu
- Zhu Feng
- Zhu Weiguo
- Zhu Ze-zhang
- Zhu Zezhang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 24/07/2017
- Field of study