33 research outputs found
Henry Wells Lawrence Memorial Lectures, Number 2
Get PDFSecond, third, and fourth lectures in a series established in honor of Henry Wells Lawrence, Professor of History at Connecticut College.
Contents of this volume are: The Pattern of Democratic Change in the United States: Andrew Jackson and Franklin Delano Roosevelt, Arthur Meier Schlesinger, Jr., Associate Professor of History, Harvard University The Problem of the Democratization of Germany, Carl Joachim Friedrich, Professor of Government, Harvard University Variations on the Liberal Theme, Alpheus Thomas Mason, McCormick Professor of Jurisprudence, Princeton Universityhttps://digitalcommons.conncoll.edu/ccbooks/1008/thumbnail.jp
Regulation of Coronary Blood Flow
Get PDFThe heart is uniquely responsible for providing its own blood supply through the coronary circulation. Regulation of coronary blood flow is quite complex and, after over 100 years of dedicated research, is understood to be dictated through multiple mechanisms that include extravascular compressive forces (tissue pressure), coronary perfusion pressure, myogenic, local metabolic, endothelial as well as neural and hormonal influences. While each of these determinants can have profound influence over myocardial perfusion, largely through effects on end-effector ion channels, these mechanisms collectively modulate coronary vascular resistance and act to ensure that the myocardial requirements for oxygen and substrates are adequately provided by the coronary circulation. The purpose of this series of Comprehensive Physiology is to highlight current knowledge regarding the physiologic regulation of coronary blood flow, with emphasis on functional anatomy and the interplay between the physical and biological determinants of myocardial oxygen delivery. © 2017 American Physiological Society. Compr Physiol 7:321-382, 2017
