8,952 research outputs found

    Comparison of individual and paired learning for the measurement of retention

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    Thesis (Ed.M.)--Boston UniversityThe purpose of this study was to measure and compare retention between children working alone and with a partner using S.R.A. (Scientific Research Associates) reading materials. The S.R.A. laboratory is a series of graded reading experiences intended to be used by individual children working alone and at their own rate of speed. Its general purpose is to improve many reading skills but in this study the retention factor will be the only concern

    Land Grant Application- Knowlton, John (Eliot)

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    Land grant application submitted to the Maine Land Office on behalf of John Knowlton for service in the Revolutionary War, by their widow Dorcas.https://digitalmaine.com/revolutionary_war_me_land_office/1542/thumbnail.jp

    A microscopic view of the yielding transition in concentrated emulsions

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    We use a custom shear cell coupled to an optical microscope to investigate at the particle level the yielding transition in concentrated emulsions subjected to an oscillatory shear deformation. By performing experiments lasting thousands of cycles on samples at several volume fractions and for a variety of applied strain amplitudes, we obtain a comprehensive, microscopic picture of the yielding transition. We find that irreversible particle motion sharply increases beyond a volume-fraction dependent critical strain, which is found to be in close agreement with the strain beyond which the stress-strain relation probed in rheology experiments significantly departs from linearity. The shear-induced dynamics are very heterogenous: quiescent particles coexist with two distinct populations of mobile and `supermobile' particles. Dynamic activity exhibits spatial and temporal correlations, with rearrangements events organized in bursts of motion affecting localized regions of the sample. Analogies with other sheared soft materials and with recent work on the transition to irreversibility in sheared complex fluids are briefly discussed.Comment: 11 pages, 10 figures. Submitted to Soft Matte

    Closing the Resource Gap: Strengthening the Nonprofit Sector in California

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    With support from The James Irvine Foundation, Nonprofit Finance Fund (NFF) used its 2015 State of the Nonprofit Sector Survey to examine California nonprofits, focusing on organizations in the San Joaquin Valley and the Inland Empire. The Foundation asked NFF to look at the challenges facing organizations in these regions, their resource needs, and their overall financial situations both on an absolute basis and in comparison to their coastal neighbors in the Bay Area and Los Angeles

    Ancient DNA from coral-hosted Symbiodinium reveal a static mutualism over the last 172 years.

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    Ancient DNA (aDNA) provides powerful evidence for detecting the genetic basis for adaptation to environmental change in many taxa. Among the greatest of changes in our biosphere within the last century is rapid anthropogenic ocean warming. This phenomenon threatens corals with extinction, evidenced by the increasing observation of widespread mortality following mass bleaching events. There is some evidence and conjecture that coral-dinoflagellate symbioses change partnerships in response to changing external conditions over ecological and evolutionary timescales. Until now, we have been unable to ascertain the genetic identity of Symbiodinium hosted by corals prior to the rapid global change of the last century. Here, we show that Symbiodinium cells recovered from dry, century old specimens of 6 host species of octocorals contain sufficient DNA for amplification of the ITS2 subregion of the nuclear ribosomal DNA, commonly used for genotyping within this genus. Through comparisons with modern specimens sampled from similar locales we show that symbiotic associations among several species have been static over the last century, thereby suggesting that adaptive shifts to novel symbiont types is not common among these gorgonians, and perhaps, symbiotic corals in general

    Effects of Environmentally Relevant Transplacental Arsenic Exposure on Mouse (Mus musculus) Hepatic Protein Expression

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    Inorganic arsenic is a well-known toxic element found around the world, but the molecular mechanisms involved in arsenic toxicity are currently poorly understood. Arsenic has been linked to several types of cancer, diabetes, cardiovascular disease, and other metabolic diseases. This project explores the toxic effects of arsenic using mouse (Mus musculus) as a mammalian model organism. Preliminary data from the Van Beneden lab has shown that mice respond to low-dose, transplacental arsenic exposure in a dose-, sex-, and generation-dependent manner. The current study addresses a potential mechanism of toxicity by determining relative expression levels of pAKT/AKT1, a serine/threonine kinase that is activated via phosphorylation. In previous Van Beneden lab studies, arsenic exposure was linked to altered expression of several gene products that are involved in cell cycle regulation as well as glucose uptake and lipid transport; each of which is known to be regulated in part by AKT. Many of these pathways are highly conserved, making AKT the subject of a significant amount of cancer and diabetes research. We hypothesized a dose-dependent increase in pAKT/AKT expression, suggesting more AKT pathway activity in response to arsenic exposure. Initial data show a trend of reduced AKT activity at 50ppb and 500ppb transplacental arsenic exposure, but no sex- dependent response or statistically significant effects of the treatment levels. Analysis of pAKT/AKT expression provides insight to the molecular pathways involved in arsenic toxicology when partnered with existing literature and results of the ongoing study in the Van Beneden laboratory

    Lutz Rathenow: Mit dem Schlimmsten wurde schon gerechnet. Prosa

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    Frankfurt a.M. and Berlin: Ullstein, 1980. 200 p., 25,- DM
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