Entre la posmodernidad y el homoerotismo: la imaginería procesional del siglo XXI y el neobarroco gay

La teoría del neobarroco gay se corresponde con un lenguaje estético que postula la exaltación del homoerotismo masculino, explícito o sutil, en clave manifiestamente morbosa y en un contexto religioso específico, aplicado a la escultura procesional de finales del siglo XX y lo que llevamos del XXI, donde además se ha tergiversado la construcción social del género en el hombre/escultura. Este proceso coincide con un espacio/tiempo donde se ha producido una creciente aceptación social de la homosexualidad masculina y su visibilidad, además de una evidente puesta en valor de la misma a través de obras donde el cuerpo del hombre sintoniza con su consideración actual como “objeto” de consumo dentro de los medios de masas.Theory of the called “Gay Neobaroque” is an aesthetic language which promotes exaltation of homoerotic and diseased senses applied to sculptural representation of men, in the particular religious context of Spanish sacred imaginery made for celebrations of Holy Week since the end of XX century to the present days and also twisting social construction of “genus” by the man/sculpture because. The called “Gay Neobaroque” is situated on specific space and time with a specific relationships with visibility, value and acceptance of masculine homosexuality and conversion of men´s body in “object” for consumers according rudiments of marketing and motif for publicity and audio-visual and artistic creation

Gamma oscillations in the temporal pole reflect the contribution of approach and avoidance motivational systems to the processing of fear and anger words

Prior reports suggest that affective effects in visual word processing cannot be fully explained by a dimensional perspective of emotions based on valence and arousal. In the current study, we focused on the contribution of approach and avoidance motivational systems that are related to different action components to the processing of emotional words. To this aim, we compared frontal alpha asymmetries and brain oscillations elicited by anger words associated with approach (fighting) motivational tendencies, and fear words that may trigger either avoidance (escaping), approach (fighting) or no (freezing) action tendencies. The participants’ task was to make decisions about approaching or distancing from the concepts represented by words. The results of cluster-based and beamforming analyses revealed increased gamma power band synchronization for fear words relative to anger words between 725 and 750 ms, with an estimated neural origin in the temporal pole. These findings were interpreted to reflect a conflict between different action tendencies underlying the representation of fear words in semantic and emotional memories, when trying to achieve task requirements. These results are in line with the predictions made by the fear-hinders-action hypothesis. Additionally, current data highlights the contribution of motivational features to the representation and processing of emotional wordsThis study was supported by the Ministerio de Ciencia, Innovación y Universidades of Spain (Grants PGC2018- 098558-B-I00, PID2019-107206GB-I00, and RED2018-102615- T), Ministerio de Economía y Competitividad of Spain (Grant PSI2017-84922-R), Comunidad de Madrid (Grants H2019/HUM-5705 and SI1/PJI/2019-00061), Universitat Rovira i Virgili (Grant 2019PFR-URV-B2-32). DH-P was funded by a predoctoral FPU20/03345 gran

La imagen y la narrativa como herramientas para el abordaje psicosocial en escenarios de violencia. Departamentos Valle del Cauca y Cauca.

El trabajo es el producto de saberes adquiridos por medio del Diplomado de Profundización Acompañamiento Psicosocial en Escenarios de Violencia; el cual propende en potenciar el quehacer del profesional de psicología en la conceptualización y adquisición de recursos de afrontamiento psicosocial en escenarios que han sufrido a causa de la violencia y han desencadenado diversas situaciones. Así mismo, la comprensión y la relevancia que coexiste en la relación vincular entre memoria, subjetividad y violencia. Siguiendo la línea del enfoque narrativo propuesta en este campo disciplinar, se realizan salas de exposiciones originales, las cuales permiten un acercamiento sensible a diferentes comunidades, dando visibilidad y cuenta de lo que cada comunidad ha vivido particularmente, también denota sus diversas expresiones culturales y nos induce a poder escuchar su voz desde la subjetividad. De forma colaborativa se selecciona el relato “Camilo” en el que se analiza los impactos psicosociales, el posicionamiento subjetivo desde el lugar de víctima o sobreviviente, el reconocimiento de significados alternos y la formulación de preguntas circulares, reflexivas y estratégicas. De igual forma, se analiza el caso Peñas Coloradas, en el que se identifican los emergentes psicosociales permitiendo la obtención de una mirada holística del sujeto en su diario vivir y los impactos generados y las configuraciones que hace de su realidad a través del proceso socio histórico cultural en el que ha estado inmerso.This work is the result of acquired knowledges through the Psychosocial Accompaniment in Scenarios of Violence Diplomat, which intends to boost the doing of psychological professional in the conceptualization and acquisition of psychosocial resources in scenarios that have suffered from violence and have triggered multiple situations. Likewise, the understanding and relevance that coexists in the bounded relation between memory, subjectivity, and violence. Following the line of the narrative approach proposed in this disciplinary field, original exhibition rooms are created, which allow a sensible approach to different communities, providing visibility and accountability of each of them, it also denotes their diverse cultural expressions, inducing us to listen their voice from subjectivity. The story "Camilo" is selected collaboratively to analyze the psychosocial impacts, the subjective positioning from the place of victim or survivor, the recognition of alternative meanings and the formulation of circular, reflexive, and strategic questions. Similarly, the Peñas Coloradas case is analyzed, in which the psychosocial emergent are identified, allowing a holistic view of the subject in his daily life and the impacts generated and the configurations he makes of his reality through the socio-historical-cultural process in which he has been immersed

Multisensor experiments over vineyard: new challenges for the GNSS-R technique

An airborne campaign was performed during August, 2014 in an agricultural area in the Duero basin (Spain) in order to appraise the synergy between very different sources of Earth Observation imagery, and very different instruments for soil moisture retrieval. During the flight, an intensive field campaign comprising soil, plant and spectral measurements was carried out. An innovative sensor based on the Global Navigation Satellite Systems Reflectometry (GNSS-R) was on board the manned vehicle, the Light Airborne Reflectometer for GNSS-R Observations (LARGO) engineered by the Universitat Politècnica de Catalunya. While the synergy between thermal, optical and passive microwave spectra observations is well known for vegetation parameters and soil moisture retrievals, the experiment aimed to evaluate the synergy of GNSS-R reflectivity with a time-collocated Landsat 8 imagery for soil moisture retrieval under semiarid climatic conditions. LARGO estimates, field measurements, and optical, NIR, SWIR and thermal bands from Landsat 8 were compared. Results showed that the joint use of GNSS-R reflectivity with vegetation and water indices together with thermal maps from Landsat 8 thoroughly improved the soil moisture estimation.Peer ReviewedPostprint (published version

Evaluating radiological response in pancreatic neuroendocrine tumours treated with sunitinib : comparison of Choi versus RECIST criteria (CRIPNET_ GETNE1504 study)

The purpose of our study was to analyse the usefulness of Choi criteria versus RECIST in patients with pancreatic neuroendocrine tumours (PanNETs) treated with sunitinib. A multicentre, prospective study was conducted in 10 Spanish centres. Computed tomographies, at least every 6 months, were centrally evaluated until tumour progression. One hundred and seven patients were included. Median progression-free survival (PFS) by RECIST and Choi were 11.42 (95% confidence interval [CI], 9.7-15.9) and 15.8 months (95% CI, 13.9-25.7). PFS by Choi (Kendall's τ = 0.72) exhibited greater correlation with overall survival (OS) than PFS by RECIST (Kendall's τ = 0.43). RECIST incorrectly estimated prognosis in 49.6%. Partial response rate increased from 12.8% to 47.4% with Choi criteria. Twenty-four percent of patients with progressive disease according to Choi had stable disease as per RECIST, overestimating treatment effect. Choi criteria predicted PFS/OS. Changes in attenuation occurred early and accounted for 21% of the variations in tumour volume. Attenuation and tumour growth rate (TGR) were associated with improved survival. Choi criteria were able to capture sunitinib's activity in a clinically significant manner better than RECIST; their implementation in standard clinical practice shall be strongly considered in PanNET patients treated with this drug

Nomogram-based prediction of survival in patients with advanced oesophagogastric adenocarcinoma receiving first-line chemotherapy: a multicenter prospective study in the era of trastuzumab

Background: To develop and validate a nomogram and web-based calculator to predict overall survival (OS) in Caucasian-advanced oesophagogastric adenocarcinoma (AOA) patients undergoing first-line combination chemotherapy. Methods: Nine hundred twenty-four AOA patients treated at 28 Spanish teaching hospitals from January 2008 to September 2014 were used as derivation cohort. The result of an adjusted-Cox proportional hazards regression was represented as a nomogram and web-based calculator. The model was validated in 502 prospectively recruited patients treated between October 2014 and December 2016. Harrell's c-index was used to evaluate discrimination. Results: The nomogram includes seven predictors associated with OS: HER2-positive tumours treated with trastuzumab, Eastern Cooperative Oncology Group performance status, number of metastatic sites, bone metastases, ascites, histological grade, and neutrophil-to-lymphocyte ratio. Median OS was 5.8 (95% confidence interval (CI), 4.5–6.6), 9.4 (95% CI, 8.5–10.6), and 14 months (95% CI, 11.8–16) for high-, intermediate-, and low-risk groups, respectively (P<0.001), in the derivation set and 4.6 (95% CI, 3.3–8.1), 12.7 (95% CI, 11.3–14.3), and 18.3 months (95% CI, 14.6–24.2) for high-, intermediate-, and low-risk groups, respectively (P<0.001), in the validation set. The nomogram is well-calibrated and reveals acceptable discriminatory capacity, with optimism-corrected c-indices of 0.618 (95% CI, 0.591–0.631) and 0.673 (95% CI, 0.636–0.709) in derivation and validation groups, respectively. The AGAMENON nomogram outperformed the Royal Marsden Hospital (c-index=0.583; P=0.00046) and Japan Clinical Oncology Group prognostic indices (c-index=0.611; P=0.03351). Conclusions: We developed and validated a straightforward model to predict survival in Caucasian AOA patients initiating first-line polychemotherapy. This model can contribute to inform clinical decision-making and optimise clinical trial design

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

APOE-by-sex interactions on brain structure and metabolism in healthy elderly controls

BACKGROUND: The APOE effect on Alzheimer Disease (AD) risk is stronger in women than in men but its mechanisms have not been established. We assessed the APOE-by-sex interaction on core CSF biomarkers, brain metabolism and structure in healthy elderly control individuals (HC). METHODS: Cross-sectional study. HC from the Alzheimer's Disease Neuroimaging Initiative with available CSF (n = 274) and/or 3T-MRI (n = 168) and/or a FDG-PET analyses (n = 328) were selected. CSF amyloid-β1-42 (Aβ1-42), total-tau (t-tau) and phospho-tau (p-tau181p) levels were measured by Luminex assays. We analyzed the APOE-by-sex interaction on the CSF biomarkers in an analysis of covariance (ANCOVA). FDG uptake was analyzed by SPM8 and cortical thickness (CTh) was measured by FreeSurfer. FDG and CTh difference maps were derived from interaction and group analyses. RESULTS: APOE4 carriers had lower CSF Aβ1-42 and higher CSF p-tau181p values than non-carriers, but there was no APOE-by-sex interaction on CSF biomarkers. The APOE-by-sex interaction on brain metabolism and brain structure was significant. Sex stratification showed that female APOE4 carriers presented widespread brain hypometabolism and cortical thinning compared to female non-carriers whereas male APOE4 carriers showed only a small cluster of hypometabolism and regions of cortical thickening compared to male non-carriers. CONCLUSIONS: The impact of APOE4 on brain metabolism and structure is modified by sex. Female APOE4 carriers show greater hypometabolism and atrophy than male carriers. This APOE-by-sex interaction should be considered in clinical trials in preclinical AD where APOE4 status is a selection criterion