1,938 research outputs found
Farmers’ Perception and Adoption of Agroforestry Practices in Faridpur District of Bangladesh
This study mainly focused on exploring perception of farmers' towards agroforestry practices and identifying the demographic factors influencing agroforestry adoption in Faridpur district. Field survey was conducted during November-December, 2016 using semi-structured questionnaire. Multi-stage random sampling was used to select upazillas, unions and villages. Snowball purposive sampling was applied to select 84 respondents in total for the questionnaire survey. Chi-square was used to test variables at 5% level of significance. Homestead agroforestry was found to be the most common agroforestry practice (39.28%), followed by fruit-based agroforestry (21.42%), woodlot plantation (13.09%) and so on. Agroforestry was perceived to increase farm productivity by 82.14% of the respondents, 73.8% opined that agroforestry increase household income, while 30.95% perceived it as a means to food security. On the contrary, 34.52% opined that agroforestry practices decrease cash crops production, 17.85% of the respondents stated agroforestry as a difficult practice. Chi-square test showed no significant association between the adoption of agroforestry practices and respondent's age (P > 0.05) or income range (P > 0.05) of the respondents. On the other hand, there is a positive significant association between the adoption of agroforestry practices and educational level (p< 0.05) as well as the farm size (p< 0.05) of the respondents. The study suggests raising awareness regarding the benefits of agroforestry practices as well as providing technical assistance
Associations between household-level exposures and all-cause diarrhea and pathogen-specific enteric infections in children enrolled in five sentinel surveillance studies
Diarrheal disease remains a major cause of childhood mortality and morbidity causing poor health and economic outcomes. In low-resource settings, young children are exposed to numerous risk factors for enteric pathogen transmission within their dwellings, though the relative importance of different transmission pathways varies by pathogen species. The objective of this analysis was to model associations between five household-level risk factors-water, sanitation, flooring, caregiver education, and crowding-and infection status for endemic enteric pathogens in children in five surveillance studies. Data were combined from 22 sites in which a total of 58,000 stool samples were tested for 16 specific enteropathogens using qPCR. Risk ratios for pathogen- and taxon-specific infection status were modeled using generalized linear models along with hazard ratios for all-cause diarrhea in proportional hazard models, with the five household-level variables as primary exposures adjusting for covariates. Improved drinking water sources conferred a 17% reduction in diarrhea risk; however, the direction of its association with particular pathogens was inconsistent. Improved sanitation was associated with a 9% reduction in diarrhea risk with protective effects across pathogen species and taxa of around 10-20% risk reduction. A 9% reduction in diarrhea risk was observed in subjects with covered floors, which were also associated with decreases in risk for zoonotic enteropathogens. Caregiver education and household crowding showed more modest, inconclusive results. Combining data from diverse sites, this analysis quantified associations between five household-level exposures on risk of specific enteric infections, effects which differed by pathogen species but were broadly consistent with hypothesized transmission mechanisms. Such estimates may be used within expanded water, sanitation, and hygiene (WASH) programs to target interventions to the particular pathogen profiles of individual communities and prioritize resources
Additive manufacturing of geopolymer composites for sustainable construction: critical factors, advancements, challenges, and future directions
Increasing pollution poses enormous pressure on the global ecosystem, with a need to limit the carbon emissions from the construction materials industry. Mitigation of this carbon is possible by converting industrial wastes into alternative cement and optimisation in the building process. Taking this into account, advancement is taking place in sustainable geopolymer composites-based additive manufacturing (AM) technology. Typical precursors for geopolymer binder are industrial waste by-products (such as slag, fly ash, and metakaolin). In another aspect, AM entails several benefits such as easy fabrication, freedom of design, the ability to generate sophisticated structural elements and reduce: expenses, time, waste generation, and labor demands. This review journal paper on geopolymer AM presents a bibliometric study followed by an overview of AM methods and influencing parameters, techniques in geopolymer AM (such as extrusion and powder bed), materials, improvements in AM process, and fresh-state and hardened-state properties. Recent developments in AM processes within the geopolymer are critically discussed while investigating the properties and applications of the same. The discussion includes an analysis pinpointing research gaps essential in developing geopolymer AM
The Burden of Cryptosporidium Diarrheal Disease among Children < 24 Months of Age in Moderate/High Mortality Regions of Sub-Saharan Africa and South Asia, Utilizing Data from the Global Enteric Multicenter Study (GEMS).
Background: The importance of Cryptosporidium as a pediatric enteropathogen in developing countries is recognized. Methods:
Data from the Global Enteric Multicenter Study (GEMS), a 3-year, 7-site, case-control study of moderate-to-severe diarrhea (MSD) and GEMS-1A (1-year study of MSD and less-severe diarrhea [LSD]) were analyzed. Stools from 12,110 MSD and 3,174 LSD cases among children aged <60 months and from 21,527 randomly-selected controls matched by age, sex and community were immunoassay-tested for Cryptosporidium. Species of a subset of Cryptosporidium-positive specimens were identified by PCR; GP60 sequencing identified anthroponotic C. parvum. Combined annual Cryptosporidium-attributable diarrhea incidences among children aged <24 months for African and Asian GEMS sites were extrapolated to sub-Saharan Africa and South Asian regions to estimate region-wide MSD and LSD burdens. Attributable and excess mortality due to Cryptosporidium diarrhea were estimated. Findings: Cryptosporidium was significantly associated with MSD and LSD below age 24 months. Among Cryptosporidium-positive MSD cases, C. hominis was detected in 77.8% (95% CI, 73.0%-81.9%) and C. parvum in 9.9% (95% CI, 7.1%-13.6%); 92% of C. parvum tested were anthroponotic genotypes. Annual Cryptosporidium-attributable MSD incidence was 3.48 (95% CI, 2.27–4.67) and 3.18 (95% CI, 1.85–4.52) per 100 child-years in African and Asian infants, respectively, and 1.41 (95% CI, 0.73–2.08) and 1.36 (95% CI, 0.66–2.05) per 100 child-years in toddlers. Corresponding Cryptosporidium-attributable LSD incidences per 100 child-years were 2.52 (95% CI, 0.33–5.01) and 4.88 (95% CI, 0.82–8.92) in infants and 4.04 (95% CI, 0.56–7.51) and 4.71 (95% CI, 0.24–9.18) in toddlers. We estimate 2.9 and 4.7 million Cryptosporidium-attributable cases annually in children aged <24 months in the sub-Saharan Africa and India/Pakistan/Bangladesh/Nepal/Afghanistan regions, respectively, and ~202,000 Cryptosporidium-attributable deaths (regions combined). ~59,000 excess deaths occurred among Cryptosporidium-attributable diarrhea cases over expected if cases had been Cryptosporidium-negative. Conclusions: The enormous African/Asian Cryptosporidium disease burden warrants investments to develop vaccines, diagnostics and therapies
Severe early onset preeclampsia: short and long term clinical, psychosocial and biochemical aspects
Preeclampsia is a pregnancy specific disorder commonly defined as de novo hypertension
and proteinuria after 20 weeks gestational age. It occurs in approximately 3-5% of pregnancies and it is still a major cause of both foetal and maternal morbidity and mortality worldwide1. As extensive research has not yet elucidated the aetiology of preeclampsia, there are no rational preventive or therapeutic interventions
available. The only rational treatment is delivery, which benefits the mother but is not in the interest of the foetus, if remote from term. Early onset preeclampsia (<32 weeks’ gestational age) occurs in less than 1% of pregnancies. It is, however often associated with maternal morbidity as the risk of progression
to severe maternal disease is inversely related with gestational age at onset2. Resulting prematurity is therefore the main cause of neonatal mortality and morbidity
in patients with severe preeclampsia3. Although the discussion is ongoing, perinatal survival is suggested to be increased in patients with preterm preeclampsia
by expectant, non-interventional management. This temporising treatment option to lengthen pregnancy includes the use of antihypertensive medication to control hypertension, magnesium sulphate to prevent eclampsia and corticosteroids
to enhance foetal lung maturity4. With optimal maternal haemodynamic status and reassuring foetal condition this results on average in an extension of 2 weeks. Prolongation of these pregnancies is a great challenge for clinicians to balance between potential maternal risks on one the eve hand and possible foetal benefits on the other. Clinical controversies regarding prolongation of preterm preeclamptic pregnancies still exist – also taking into account that preeclampsia is the leading cause of maternal mortality in the Netherlands5 - a debate which is even more pronounced in very preterm pregnancies with questionable foetal viability6-9. Do maternal risks of prolongation of these very early pregnancies outweigh
the chances of neonatal survival? Counselling of women with very early onset preeclampsia not only comprises of knowledge of the outcome of those particular pregnancies, but also knowledge of outcomes of future pregnancies of these women is of major clinical importance.
This thesis opens with a review of the literature on identifiable risk factors of preeclampsia
Design and Analysis of an AC Coupled Photovoltaic System for an Off-grid Community in Chittagong Hill Tracts
This paper presents the design of an AC-coupled off-grid photovoltaic (PV) system for a remote village in the Chittagong Hill Tracts of Bangladesh which has no access to national utility grid. A field survey was conducted to collect load demand data of the population for designing an optimal PV system architecture to serve that community. The proposed system consists of 18 kW PV arrays, two 6 kW grid-tied inverters, a 6 kW battery inverter and a 19.2 kWh nominal capacity battery bank. Further, the technical feasibility of the system was evaluated using HOMER (Hybrid Optimization Model for Electric Renewable) Pro software. The analytical results indicate that the proposed AC-coupled stand-alone solar system can meet a load demand of 46.58 kWh at daytime and 7.02 kWh at night in that village. Currently, the infrastructure of proposed PV plant as well as the transmission and distribution network are being developed at the selected site. Moreover, insights into the benefits of AC-coupling over DC-coupling for large off-grid systems in remote hilly areas are provided in the paper
Microbiota that affect risk for shigellosis in children in low-income countries
Pathogens in the gastrointestinal tract exist within a vast population of microbes. We examined associations between pathogens and composition of gut microbiota as they relate to Shigella spp./enteroinvasive Escherichia coli infection. We analyzed 3,035 stool specimens (1,735 nondiarrheal and 1,300 moderate-to-severe diarrheal) from the Global Enteric Multicenter Study for 9 enteropathogens. Diarrheal specimens had a higher number of enteropathogens (diarrheal mean 1.4, nondiarrheal mean 0.95; p<0.0001). Rotavirus showed a negative association with Shigella spp. in cases of diarrhea (odds ratio 0.31, 95% CI 0.17–0.55) and had a large combined effect on moderate-to-severe diarrhea (odds ratio 29, 95% CI 3.8–220). In 4 Lactobacillus taxa identified by 16S rRNA gene sequencing, the association between pathogen and disease was decreased, which is consistent with the possibility that Lactobacillus spp. are protective against Shigella spp.–induced diarrhea. Bacterial diversity of gut microbiota was associated with diarrhea status, not high levels of the Shigella spp. ipaH gene.publishedVersio
The Impact of Generic Data Structures: Decoding the Role of Lists in the Linux Kernel
International audienceThe increasing adoption of the Linux kernel has been sustained by a large and constant maintenance effort, performed by a wide and heterogeneous base of contributors. One important problem that maintainers face in any code base is the rapid understanding of complex data structures. The Linux kernel is written in the C language, which enables the definition of arbitrarily uninformative datatypes, via the use of casts and pointer arithmetic, of which doubly linked lists are a prominent example. In this paper, we explore the advantages and disadvantages of such lists, for expressivity, for code understanding, and for code reliability. Based on our observations, we have developed a toolset that includes inference of descriptive list types and a tool for list visualization. Our tools identify more than 10,000 list fields and variables in recent Linux kernel releases and succeeds in typing 90%. We show how these tools could have been used to detect previously fixed bugs and identify 6 new ones
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