Termination of the leprosy isolation policy in the US and Japan : Science, policy changes, and the garbage can model

BACKGROUND: In both the US and Japan, the patient isolation policy for leprosy /Hansen's disease (HD) was preserved along with the isolation facilities, long after it had been proven to be scientifically unnecessary. This delayed policy termination caused a deprivation of civil liberties of the involuntarily confined patients, the fostering of social stigmas attached to the disease, and an inefficient use of health resources. This article seeks to elucidate the political process which hindered timely policy changes congruent with scientific advances. METHODS: Examination of historical materials, supplemented by personal interviews. The role that science played in the process of policy making was scrutinized with particular reference to the Garbage Can model. RESULTS: From the vantage of history, science remained instrumental in all period in the sense that it was not the primary objective for which policy change was discussed or intended, nor was it the principal driving force for policy change. When the argument arose, scientific arguments were employed to justify the patient isolation policy. However, in the early post-WWII period, issues were foregrounded and agendas were set as the inadvertent result of administrative reforms. Subsequently, scientific developments were more or less ignored due to concern about adverse policy outcomes. Finally, in the 1980s and 1990s, scientific arguments were used instrumentally to argue against isolation and for the termination of residential care. CONCLUSION: Contrary to public expectations, health policy is not always rational and scientifically justified. In the process of policy making, the role of science can be limited and instrumental. Policy change may require the opening of policy windows, as a result of convergence of the problem, policy, and political streams, by effective exercise of leadership. Scientists and policymakers should be attentive enough to the political context of policies

Design procedures of reinforced concrete framed buildings in Nepal and its impact on seismic safety

The present paper analyses the design procedure and its impact on seismic safety of the structures. For this, a representative reinforced concrete frame building (WDS) is designed and the results are compared with similar buildings detailed with: i) Current Construction Practices (CCP); ii) the Nepal Building Code (NBC) and iii) the Modified Nepal Building Code (NBC+) recommendations. The seismic performance evaluation is done with global strength, inter-storey drift and displacement of the structures. Likewise, the sensitivity of the structural and geometrical parameters of the RC frame building is studied through nonlinear analysis. The study parameters considered for parametric analysis are column size, beam size, inter-storey height, bay length, bay width, and compressive strength of concrete. The results show that the influence on the structural behaviour, particularly by variation in column size and inter-storey height. Additionally, the influence of the seismic zone factor on reinforcement demand of the structure is studied. The result shows that structures designed for high to medium seismic hazard demands double the reinforcement in beams compared to structures in low seismic zone

Higher harmonic anisotropic flow measurements of charged particles in Pb-Pb collisions at 2.76 TeV

We report on the first measurement of the triangular $v_3$, quadrangular $v_4$, and pentagonal $v_5$ charged particle flow in Pb-Pb collisions at 2.76 TeV measured with the ALICE detector at the CERN Large Hadron Collider. We show that the triangular flow can be described in terms of the initial spatial anisotropy and its fluctuations, which provides strong constraints on its origin. In the most central events, where the elliptic flow $v_2$ and $v_3$ have similar magnitude, a double peaked structure in the two-particle azimuthal correlations is observed, which is often interpreted as a Mach cone response to fast partons. We show that this structure can be naturally explained from the measured anisotropic flow Fourier coefficients.Comment: 10 pages, 4 figures, published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/387

Pseudorapidity dependence of the anisotropic flow of charged particles in Pb–Pb collisions at sNN=2.76 TeV

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