Galaxy-Targeting Approach Optimized for Finding the Radio Afterglows of Gravitational Wave Sources

Kilonovae and radio afterglows of neutron star merger events have been identified as the two most promising counterparts, of these gravitational wave sources, that can provide arcsecond localization. While several new and existing optical search facilities have been dedicated to finding kilonovae, factors such as dust obscuration and the daytime sky may thwart these searches in a significant fraction of gavitational wave events. Radio-only searches, being almost immune to these factors, are equally capable of finding the counterparts and in fact offer a complementary discovery approach, despite the modest fields of view for many of the present-day radio interferometers. Such interferometers will be able to carry out competitive searches for the electromagnetic counterparts through the galaxy targeting approach. Adapting and improving on an existing algorithm by Rana et al. 2017. we present here a method that optimizes the placement of radio antenna pointings, integration time, and antenna slew. We simulate 3D gravitational wave localizations to find the efficacy of our algorithm; with substantial improvements in slew overhead and containment probability coverage, our algorithm performs significantly better than simple galaxy-rank-ordered observations. We propose that telescopes such as the Very Large Array, MeerKAT, Australia Telescope Compact Array and the Gaint Meterwave Radio Telescope, having fields of view $\lesssim$1 deg$^2$ and searching for the counterparts of nearby GW events over tens of square degrees or larger, will especially benefit from this optimized galaxy-targeting approach for electromagnetic counterpart searches.Comment: 13 pages, 7 figures, Submitted to Ap

Antibacterial and antifungal evaluation of some chalcogen bearing ligands, their transition and nontransition metal complexes

Eight chalcogen bearing compounds, 3-(4-fluorophenyl telluro) propylamine (1), 3-(phenyl telluro)propylammonium acetate salt (2), 3-(phenyl telluro)propylacetamide (3) and α-(phenylseleno) acetic acid (4) (1-4 are ligands), [Ph2Sn(Cl).1](NO3 ) (5), [Ph3Sn.1](BPh4 ) (6), [ZnCl2 .2] (7) and [CdCl2.2] (8) (5-8 are complexes of 1 and 2) were synthesised and screened for antibacterial activity against Gram-positive bacterial strains of Staphylococcus aureus, Bacillus anthracis and the Gramnegative bacteria Escherchia coli. They were also tested for their antifungal activity against Candida tropicalis, Trichophyton rubrum and Asperegillus niger, by using the disk diffusion technique. Inhibition zones demonstrated that compounds 1–3 showed significant activity, due to the presence of N in the form of amine group however Compound 4 bearing an acidic group, shows higher activity against bacterial strains. Compounds 5–8 (having Sn, Zn and Cd in their framework) showed still higher activities, due to increase in the lipophilicity and easier penetration of the compounds into the outer cell wall of the microorganisms, which causes death due to cell membrane rupturing. Compounds 1–8 were most effective against E. coli (bacterial strains), as the cell wall of Gram-negative strains have thin outer lipid membrane, which is made up of lipopolysaccharides. These compounds showed slightly reduced antifungal activity, because the cell wall of fungi is made up of chitin, which is difficult to cross. It could be concluded, from the obtained results that the biological activity of compounds is essentially determined by the number and nature of the organic groups and central metal ion. The presence of NH2, COOH group as well as metal ion like Sn, Zn, Cd in the compounds leads to higher activity

Cloud-Based Essentail Home Services Aggrregator

Cloud-based Home services aggregator aims to provide the much needed and essential everyday services to the consumers in an easy and affordable manner. This project basically brings technology to the doorsteps of both the employee and the employer and helps them connect in a never before manner.  The importance and impact of this paper is clearly visible in the present and pressing times of the Covid epidemic. This project demonstrates a workflow model that can function irrespective of the epidemic conditions and at the same time minimize the risk of virus infection by reducing people to people contact. Despite the reduction in contact the work quality is not affected. Tough times such as an epidemic call on for these services as essential and important much more than ever. Through this project we bring a common platform to those who provide the services and those who need it. The scope of the provided services ranges from basic home cleaning, car wash, laundry to much more. The project also aims to bring to platform the large - feature phone using - Indian workforce. The limited capabilities of the existing infrastructure hinder this section of workforce from connecting to better work opportunities. A potentially large number of footsteps on the side may cause it to render slowly. And so, project is built up in cloud technology

Acute superior vena cava obstruction due to tight pericardial closure following congenital defect repair

The obstruction of the superior vena cava (SVC) of acute onset nature following surgery is a rare and serious condition. The tight closure of the pericardium over the heart during surgical procedures may cause external compression on the SVC. Echocardiography and Computed tomography (CT) scan aids in the diagnosis. Cutting open the pericardial stitches relieves the condition

Activated Protein C Ameliorates Tubular Mitochondrial Reactive Oxygen Species and Inflammation in Diabetic Kidney Disease

Diabetic kidney disease (DKD) is an emerging pandemic, paralleling the worldwide increase in obesity and diabetes mellitus. DKD is now the most frequent cause of end-stage renal disease and is associated with an excessive risk of cardiovascular morbidity and mortality. DKD is a consequence of systemic endothelial dysfunction. The endothelial-dependent cytoprotective coagulation protease activated protein C (aPC) ameliorates glomerular damage in DKD, in part by reducing mitochondrial ROS generation in glomerular cells. Whether aPC reduces mitochondrial ROS generation in the tubular compartment remains unknown. Here, we conducted expression profiling of kidneys in diabetic mice (wild-type and mice with increased plasma levels of aPC, APChigh mice). The top induced pathways were related to metabolism and in particular to oxidoreductase activity. In tubular cells, aPC maintained the expression of genes related to the electron transport chain, PGC1-α expression, and mitochondrial mass. These effects were associated with reduced mitochondrial ROS generation. Likewise, NLRP3 inflammasome activation and sterile inflammation, which are known to be linked to excess ROS generation in DKD, were reduced in diabetic APChigh mice. Thus, aPC reduces mitochondrial ROS generation in tubular cells and dampens the associated renal sterile inflammation. These studies support approaches harnessing the cytoprotective effects of aPC in DKD

The Panchromatic Afterglow of GW170817: The full uniform dataset, modeling, comparison with previous results and implications

We present the full panchromatic afterglow light curve data of GW170817, including new radio data as well as archival optical and X-ray data, between 0.5 and 940 days post-merger. By compiling all archival data, and reprocessing a subset of it, we have ensured that the panchromatic dataset is uniform and therefore immune to the differences in data processing or flux determination methods used by different groups. Simple power-law fits to the uniform afterglow light curve indicate a t^(0.86±0.04) rise, a t^(−1.90±0.12) decline, and a peak occurring at 155±4 days. The afterglow is optically thin throughout its evolution, consistent with a single spectral index (−0.569±0.002) across all epochs. This gives a precise and updated estimate of the electron power-law index, p=2.138±0.004. By studying the diffuse X-ray emission from the host galaxy, we place a conservative upper limit on the hot ionized ISM density, <0.01 cm⁻³, consistent with previous afterglow studies. Using the late-time afterglow data we rule out any long-lived neutron star remnant having magnetic field strength between 10^(10.4) G and 10¹⁶ G. Our fits to the afterglow data using an analytical model that includes VLBI proper motion from Mooley et al (2018), and a structured jet model that ignores the proper motion, indicates that the proper motion measurement needs to be considered while seeking an accurate estimate of the viewing angle

Production of He-4 and (4) in Pb-Pb collisions at root(NN)-N-S=2.76 TeV at the LHC

Results on the production of He-4 and (4) nuclei in Pb-Pb collisions at root(NN)-N-S = 2.76 TeV in the rapidity range vertical bar y vertical bar <1, using the ALICE detector, are presented in this paper. The rapidity densities corresponding to 0-10% central events are found to be dN/dy4(He) = (0.8 +/- 0.4 (stat) +/- 0.3 (syst)) x 10(-6) and dN/dy4 = (1.1 +/- 0.4 (stat) +/- 0.2 (syst)) x 10(-6), respectively. This is in agreement with the statistical thermal model expectation assuming the same chemical freeze-out temperature (T-chem = 156 MeV) as for light hadrons. The measured ratio of (4)/He-4 is 1.4 +/- 0.8 (stat) +/- 0.5 (syst). (C) 2018 Published by Elsevier B.V.Peer reviewe

Laparoscopic repair of gastro-duodenal fistula secondary to band erosion

Laparoscopic gastric banding is one of the most common surgical treatments for morbid obesity performed worldwide. The procedure, however, has many well-documented risks and complications, including band erosion. We present here a gastric banding patient who was referred to our tertiary care centre after secondarily forming an entero-enteric fistula with complaints of pain, nausea, vomiting and severe reflux. She was successfully treated with laparoscopic dissection and due to her existing anatomy, and the patient′s desire for continued weight loss, she was converted to Roux-en-Y gastric bypass

Nitrofurantoin: Furious against bacteria? An in vitro study to test nitrofurantoin as an intracanal medicament against Enterococcus Faecalis

In vitro evaluation of nitrofurantoin as an intracanal medicament against Enterococcus Faecalis. Materials and Methods: 150 single-rooted premolar teeth were chosen and instrumented using a Protaper gold rotary file system; the root canals of these teeth were inoculated for 21 days with an Enterococcus faecalis bacterial solution. The canals were inoculated with Nitrofurantoin, Calcium hydroxide, and MTAP after 21 days and left for 7 days. On the eighth day, the samples were examined to determine the degree of infection. The study's findings revealed that both Nitrofurantoin and MTAP were very successful, with no Colony Forming Units (CFU) production in their respective groups. The current investigation indicated that nitrofurantoin is effective in eradicating E. faecalis cells in pure culture as well as root canals