10 research outputs found

    Development of a speech analyser/synthesizer for special applications in linguistics

    No full text
    This project on the development of a speech analyzer/synthesiser for special applications in linguistics was proposed for the purpose of developing computer software for the alteration of the prosodic characteristics of speech signals in the English Language.RP 12/8

    6-exo-trig Michael addition-lactonizations for catalytic enantioselective chromenone synthesis

    No full text
    The authors thank the EPSRC Centre for Doctoral Training in Critical Resource Catalysis (CRITICAT, grant code EP/L016419/1, RMNP) for funding.The European Research Council under the European Union’s Seventh Framework Programme (FP7/2007-2013) ERC Grant Agreement No. 279850 is also acknowledged. ADS thanks the Royal Society for a Wolfson Research Merit AwardThe catalytic enantioselective 6-exo-trig Michael addition-lactonization of enone-acid substrates to form cis-chromenones with high diastereo- and enantiocontrol was developed using the commercially available isothiourea tetramisole. An acidic workup proved necessary to minimize product epimerization and maximize product er, providing cis-chromenones in excellent yield, and with excellent diastereo- and enantioselectivity.Publisher PDFPeer reviewe

    Secretion of recombinant proteins from E. coli

    No full text
    corecore