373 research outputs found
TOR complex 2 is needed for cell cycle progression and anchorage-independent growth of MCF7 and PC3 tumor cells
- Author
- Publication venue
- BioMed Central
- Publication date
- 01/01/2008
- Field of study
<p>Abstract</p> <p>Background</p> <p>AKT signaling promotes cell growth, proliferation and survival and is hyperactivated in many cancers. TOR complex 2 (TORC2) activates AKT by phosphorylating it on the 'hydrophobic motif' site. Hydrophobic motif site phosphorylation is needed only for a subset of AKT functions. Whether proliferation of tumor cells depends on TORC2 activity has not been thoroughly explored.</p> <p>Methods</p> <p>We used RNAi-mediated knockdown of rictor to inhibit TORC2 activity in MCF7 and PC3 tumor cells to analyze the importance of TORC2 on proliferation of tumor cells.</p> <p>Results</p> <p>TORC2 inhibition reduced proliferation and anchorage-independent growth of both cell lines. Rictor depleted cells accumulated G1 phase, and showed prominent downregulation of Cyclin D1.</p> <p>Conclusion</p> <p>This study provides further evidence that inhibition of TORC2 activity might be a useful strategy to inhibit proliferation of tumor cells and subsequent tumor growth.</p
The direct healthcare costs associated with psychological distress and major depression : A population-based cohort study in Ontario, Canada
- Author
- A Drapeau
- AS Gershon
- AS Gershon
- Bruce A Larson
- C Pearson
- CE Dismuke
- CJ Muller
- Claire de Oliveira
- CM Thomas
- HJ Grabe
- J Cairney
- JE Hux
- JG Green
- JM Donohue
- Joyce Cheng
- K Kleine-Budde
- K Tu
- K Tu
- KE Lasser
- KH McVeigh
- LA Pratt
- LS Steele
- M Ekman
- M Luppa
- M Luppa
- Maria Chiu
- Michael Lebenbaum
- MT Nguyen
- NP Roos
- P Cuijpers
- PA Pirraglia
- Paul Kurdyak
- PE Greenberg
- PT Katzmarzyk
- R Sturm
- RC Kessler
- RC Kessler
- RC Kessler
- RC Kessler
- SE Schultz
- SN Vigod
- WG Manning
- WG Manning
- WG Manning Jr
- WJ Katon
- Y Tomonaga
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 05/09/2017
- Field of study
The objective of our study was to estimate direct healthcare costs incurred by a population-based sample of people with psychological distress or depression. We used the 2002 Canadian Community Health Survey on Mental Health and Well Being and categorized individuals as having psychological distress using the Kessler-6, major depressive disorder (MDD) using DSM-IV criteria and a comparison group of participants without MDD or psychological distress. Costs in 2013 USD were estimated by linking individuals to health administrative databases and following them until March 31, 2013. Our sample consisted of 9,965 individuals, of whom 651 and 409 had psychological distress and MDD, respectively. Although the age-and-sex adjusted per-capita costs were similarly high among the psychologically distressed (3,364,952,791, 3,937)andthosewithMDD(3,210, 95% CI: 2,413,4,008) compared to the comparison group (2,629,952,312, 2,945),thepopulation−wideexcesscostsforpsychologicaldistress(441 million) were more than twice that for MDD ($210 million) as there was a greater number of people with psychological distress than depression. We found substantial healthcare costs associated with psychological distress and depression, suggesting that psychological distress and MDD have a high cost burden and there may be public health intervention opportunities to relieve distress. Further research examining how individuals with these conditions use the healthcare system may provide insight into the allocation of limited healthcare resources while maintaining high quality care
Eukaryotic Protein Kinases (ePKs) of the Helminth Parasite Schistosoma mansoni
- Author
- A Ahier
- A Ahier
- A Capes-Davis
- A Osman
- A Rambaut
- A Zerlotini
- Adhemar Zerlotini
- AK Kalis
- AL Jackson
- AM Gurnett
- B Pils
- B Stronach
- B Zhou
- BC Van
- BE Swierczewski
- C Dissous
- C Gally
- C Naula
- C Notredame
- CA Bradham
- CA Diaz
- CR Caffrey
- D Bahia
- D Bahia
- D Bahia
- D Bahia
- D Miranda-Saavedra
- E Ghedin
- EM Zdobnov
- F Aguero
- F Ludolf
- G Manning
- G Manning
- G Manning
- GD Plowman
- GI Gallicano
- Guilherme Oliveira
- H Mellor
- H Ramachandran
- J Boudeau
- J Felsenstein
- J Knobloch
- J Moffat
- J Ren
- J Vicogne
- Jerônimo C Ruiz
- JJ Eckert
- JJ Kim
- JJ Vowels
- JM Fitzpatrick
- JP Webster
- K Anamika
- K Deshmukh
- K Kapp
- K Kapp
- K Katoh
- K Kemphues
- K Kondoh
- K Rutherford
- KEGG
- KinBase
- L Pica-Mattoccia
- Laila A Nahum
- Larissa L Silva
- Luiza F Andrade
- Lívia GA Avelar
- M Berriman
- M Bhagwat
- M Knockaert
- M Parsons
- M Salzet
- M Waisberg
- M Waisberg
- MG Wilkinson
- MH Ludtmann
- MJ Beall
- MJ Doenhoff
- MJ Doenhoff
- MT Swulius
- MV Sundaram
- N Khayath
- P Ward
- PJ Muhlrad
- PJ Parker
- PR Dohrmann
- PT Lin
- PT LoVerde
- PT LoVerde
- R Steinhart
- RA Wilson
- RD Finn
- RG Donald
- RM Eglen
- S Beckmann
- S Caenepeel
- S Hunter
- S Lehtonen
- S Nishimoto
- S Noselli
- S Verjovski-Almeida
- SD Melman
- SG Forrester
- SJ Davies
- SK Hanks
- SK Hanks
- SK Hanks
- SN Boyle
- SS Taylor
- T Hall
- T Tanoue
- T Tanoue
- V Reinke
- W Haas
- W Haas
- W Hu
- W Kunz
- Y Yan
- ZG Han
- Publication venue
- BioMed Central
- Publication date
- 01/01/2011
- Field of study
<p>Abstract</p> <p>Background</p> <p>Schistosomiasis remains an important parasitic disease and a major economic problem in many countries. The <it>Schistosoma mansoni </it>genome and predicted proteome sequences were recently published providing the opportunity to identify new drug candidates. Eukaryotic protein kinases (ePKs) play a central role in mediating signal transduction through complex networks and are considered druggable targets from the medical and chemical viewpoints. Our work aimed at analyzing the <it>S. mansoni </it>predicted proteome in order to identify and classify all ePKs of this parasite through combined computational approaches. Functional annotation was performed mainly to yield insights into the parasite signaling processes relevant to its complex lifestyle and to select some ePKs as potential drug targets.</p> <p>Results</p> <p>We have identified 252 ePKs, which corresponds to 1.9% of the <it>S. mansoni </it>predicted proteome, through sequence similarity searches using HMMs (Hidden Markov Models). Amino acid sequences corresponding to the conserved catalytic domain of ePKs were aligned by MAFFT and further used in distance-based phylogenetic analysis as implemented in PHYLIP. Our analysis also included the ePK homologs from six other eukaryotes. The results show that <it>S. mansoni </it>has proteins in all ePK groups. Most of them are clearly clustered with known ePKs in other eukaryotes according to the phylogenetic analysis. None of the ePKs are exclusively found in <it>S. mansoni </it>or belong to an expanded family in this parasite. Only 16 <it>S. mansoni </it>ePKs were experimentally studied, 12 proteins are predicted to be catalytically inactive and approximately 2% of the parasite ePKs remain unclassified. Some proteins were mentioned as good target for drug development since they have a predicted essential function for the parasite.</p> <p>Conclusions</p> <p>Our approach has improved the functional annotation of 40% of <it>S. mansoni </it>ePKs through combined similarity and phylogenetic-based approaches. As we continue this work, we will highlight the biochemical and physiological adaptations of <it>S. mansoni </it>in response to diverse environments during the parasite development, vector interaction, and host infection.</p
An overview of the recent developments on fructooligosaccharide production and applications
- Author
- A Dominguez
- A Goulas
- A Hosono
- A Lateef
- A Madlová
- A Madlová
- A Nemukula
- A Pandey
- A Zuccaro
- AB Dhake
- AC Nilsson
- AE Maiorano
- AGJ Voragen
- AJJ Straathof
- AK Balasubramaniem
- Ana Luísa Dominguez
- B Metz
- C Kunz
- CC Lim
- CJ Chiang
- CJ Ziemer
- D-C Sheu
- DC Sheu
- DP Burkitt
- F Brighenti
- F Clydesdale
- F Pierre
- FP Chávez
- FVA Risso
- GLF Wallis
- GR Gibson
- GR Gibson
- GT Macfarlane
- GTC Delgado
- H Szajewska
- H-L Chen
- HT Shin
- I Ghazi
- I Ghazi
- I Siró
- J Yoshikawa
- J Yoshikawa
- J Yoshikawa
- J-P Park
- José António Teixeira
- JR Korzenik
- JS Lim
- JW Yun
- JW Yun
- K Menrad
- K Nishizawa
- KG Jackson
- KS Belghith
- L L’Hocine
- L Raschka
- L-M Wang
- Lígia Raquel Rodrigues
- M Antošová
- M Antošová
- M Bekers
- M Bugaut
- M Fiordaliso
- M Fujishima
- M Gudiel-Urbano
- M Jedrzejczak-Krzepkowska
- M Piñeiro
- M Roberfroid
- M Roberfroid
- M Shimizu
- M Vandáková
- MA Ganaie
- MA Levrat
- MA Yu Wang
- MB Prata
- MB Roberfroid
- MB Roberfroid
- MJ Playne
- ML Sanz
- MR Druce
- N Bennett
- N Saad
- N Shiomi
- Nelson Manuel Lima
- NM Delzenne
- NM Delzenne
- O Hernández
- OB Chaudhri
- PD Schley
- PT Sangeetha
- PT Sangeetha
- PT Sangeetha
- PT Sangeetha
- PT Sangeetha
- QD Nguyen
- QD Nguyen
- R Simmering
- RG Crittenden
- RS Singh
- S Baba
- S Hayashi
- S Mishra
- SAFT Hijum van
- SH Yoon
- SI Mussatto
- SI Mussatto
- SI Mussatto
- SI Mussatto
- SR Glore
- T Tokunaga
- T-J Lin
- TS Manning
- U Hölker
- U Munjal
- V Preter De
- W Scheppach
- W-C Chen
- W-C Lee
- WC Chen
- X Qiang
- Y Yamamoto
- YS Kim
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
Over the past years, many researchers have suggested
that deficiencies in the diet can lead to disease states
and that some diseases can be avoided through an adequate
intake of relevant dietary components. Recently, a great interest
in dietary modulation of the human gut has been registered.
Prebiotics, such as fructooligosaccharides (FOS), play a key
role in the improvement of gut microbiota balance and in
individual health. FOS are generally used as components of
functional foods, are generally regarded as safe (generally
recognized as safe status—from the Food and Drug Administration,
USA), and worth about 150€ per kilogram. Due to
their nutrition- and health-relevant properties, such as moderate
sweetness, low carcinogenicity, low calorimetric value,
and low glycemic index, FOS have been increasingly used
by the food industry. Conventionally, FOS are produced
through a two-stage process that requires an enzyme production
and purification step in order to proceed with the chemical
reaction itself. Several studies have been conducted on the
production of FOS, aiming its optimization toward the development
of more efficient production processes and their potential
as food ingredients. The improvement of FOS yield and
productivity can be achieved by the use of different fermentative
methods and different microbial sources of FOS producing
enzymes and the optimization of nutritional and
culture parameter; therefore, this review focuses on the latest
progresses in FOS research such as its production, functional
properties, and market data.Agencia de Inovacao (AdI)-Project BIOLIFE reference PRIME 03/347. Ana Dominguez acknowledges Fundacao para a Ciencia e a Tecnologia, Portugal, for her PhD grant reference SFRH/BD/23083/2005
Targeting ανβ3 and ανβ5 inhibits photon-induced hypermigration of malignant glioma cells
- Author
- Angela Mohr
- BB Tysnes
- C Wild-Bode
- CL Gladson
- CP Geer
- Daniel Habermehl
- DP White
- E Giannopoulou
- H Sasaki
- HS Friedman
- JM Albert
- Jürgen Debus
- K Goetze
- Katja Lindel
- KD McCall-Culbreath
- Klaus Weber
- L Bello
- Lena Wuerth
- M Hartmann
- M Wolff
- MD Walker
- ME Beckner
- N Cordes
- P Roca-Cusachs
- PT Caswell
- R Stupp
- RH Goldbrunner
- RJ Seitz
- S Huang
- S Monferran
- SE Combs
- SK Chintala
- Stefan Rieken
- Stephanie E Combs
- SX Yang
- T Ogata
- TJ Manning Jr
- V Senner
- W Paulus
- Y Fukushima
- Publication venue
- BioMed Central
- Publication date
- 01/01/2011
- Field of study
Crystal Structures of the FAK Kinase in Complex with TAE226 and Related Bis-Anilino Pyrimidine Inhibitors Reveal a Helical DFG Conformation
- Author
- AK Sood
- B Nagar
- B Nagar
- C Pargellis
- CD Mol
- D Lietha
- Daniel Lietha
- G Jones
- G Manning
- GN Murshudov
- HN Antoniades
- J Griffith
- J Halder
- J Nowakowski
- JD Hildebrand
- JF Beattie
- JT Parsons
- L Del Valle
- L Tremblay
- LC Storoni
- LV Owens
- M Huse
- M Natarajan
- MA Seeliger
- MB Lamers
- MC Heinrich
- Michael J. Eck
- Mikhail V. Blagosklonny
- NM Han
- P Emsley
- PT Wan
- PW Manley
- Q Shi
- SK Mitra
- SR Hubbard
- T Bonome
- TJ Liu
- VM Golubovskaya
- WG Cance
- WG Roberts
- Z Otwinowski
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2008
- Field of study
Focal Adhesion Kinase (FAK) is a non-receptor tyrosine kinase required for cell migration, proliferation and survival. FAK overexpression has been documented in diverse human cancers and is associated with a poor clinical outcome. Recently, a novel bis-anilino pyrimidine inhibitor, TAE226, was reported to efficiently inhibit FAK signaling, arrest tumor growth and invasion and prolong the life of mice with glioma or ovarian tumor implants. Here we describe the crystal structures of the FAK kinase bound to TAE226 and three related bis-anilino pyrimidine compounds. TAE226 induces a conformation of the N-terminal portion of the kinase activation loop that is only observed in FAK, but is distinct from the conformation in both the active and inactive states of the kinase. This conformation appears to require a glycine immediately N-terminal to the “DFG motif”, which adopts a helical conformation stabilized by interactions with TAE226. The presence of a glycine residue in this position contributes to the specificity of TAE226 and related compounds for FAK. Our work highlights the fact that kinases can access conformational space that is not necessarily utilized for their native catalytic regulation, and that such conformations can explain and be exploited for inhibitor specificity
Observation of associated near-side and away-side long-range correlations in √sNN=5.02 TeV proton-lead collisions with the ATLAS detector
- Author
- Aad G
- Abajyan T
- Abbott B
- Abdallah J
- Abdel Khalek S
- Abdelalim AA
- Abdinov O
- Aben R
- Abi B
- Abolins M
- Abouzeid OS
- Abramowicz H
- Abreu H
- Acharya BS
- Adamczyk L
- Adams DL
- Addy TN
- Adelman J
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Agustoni M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akesson TP
- Akimoto G
- Akimov AV
- Alam MA
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Allbrooke BM
- Allison LJ
- Allport PP
- Allwood-Spiers SE
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alonso F
- Altheimer A
- Alvarez Gonzalez B
- Alviggi MG
- Amako K
- Amelung C
- Ammosov VV
- Amor Dos Santos SP
- Amorim A
- Amoroso S
- Amram N
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anderson KJ
- Andreazza A
- Andrei V
- Anduaga XS
- Angelidakis S
- Anger P
- Angerami A
- Anghinolfi F
- Anisenkov A
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
- Antonov A
- Antos J
- Anulli F
- Aoki M
- Aperio Bella L
- Apolle R
- Arabidze G
- Aracena I
- Arai Y
- Arce AT
- Arfaoui S
- Arguin JF
- Argyropoulos S
- Arik E
- Arik M
- Armbruster AJ
- Arnaez O
- Arnal V
- Artamonov A
- Artoni G
- Arutinov D
- Asai S
- Ask S
- Asman B
- Asquith L
- Assamagan K
- Astalos R
- Astbury A
- Atkinson M
- ATLAS Collaboration The
- Auerbach B
- Auge E
- Augsten K
- Aurousseau M
- Avolio G
- Axen D
- Azuelos G
- Azuma Y
- Baak MA
- Baccaglioni G
- Bacci C
- Bach AM
- Bachacou H
- Bachas K
- Backes M
- Backhaus M
- Backus Mayes J
- Badescu E
- Bagnaia P
- Bai Y
- Bailey DC
- Bain T
- Baines JT
- Baker OK
- Baker S
- Balek P
- Balli F
- Banas E
- Banerjee P
- Banerjee S
- Banfi D
- Bangert A
- Bansal V
- Bansil HS
- Barak L
- Baranov SP
- Barber T
- Barberio EL
- Barberis D
- Barbero M
- Bardin DY
- Barillari T
- Barisonzi M
- Barklow T
- Barlow N
- Barnett BM
- Barnett RM
- Baroncelli A
- Barone G
- Barr AJ
- Barreiro Guimarães da Costa J
- Barreiro F
- Bartoldus R
- Barton AE
- Bartsch V
- Basye A
- Bates RL
- Batkova L
- Batley JR
- Battaglia A
- Battistin M
- Bauer F
- Bawa HS
- Beale S
- Beau T
- Beauchemin PH
- Beccherle R
- Bechtle P
- Beck HP
- Becker K
- Becker S
- Beckingham M
- Becks KH
- Beddall A
- Beddall AJ
- Bedikian S
- Bednyakov VA
- Bee CP
- Beemster LJ
- Beermann TA
- Begel M
- Behar Harpaz S
- Belanger-Champagne C
- Bell PJ
- Bell WH
- Bella G
- Bellagamba L
- Bellomo M
- Belloni A
- Beloborodova O
- Belotskiy K
- Beltramello O
- Benary O
- Benchekroun D
- Bendtz K
- Benekos N
- Benhammou Y
- Benhar Noccioli E
- Benitez Garcia JA
- Benjamin DP
- Benoit M
- Bensinger JR
- Benslama K
- Bentvelsen S
- Berge D
- Bergeaas Kuutmann E
- Berger N
- Berghaus F
- Berglund E
- Beringer J
- Bernat P
- Bernhard R
- Bernius C
- Bernlochner FU
- Berry T
- Bertella C
- Bertin A
- Bertolucci F
- Besana MI
- Besjes GJ
- Besson N
- Bethke S
- Bhimji W
- Bianchi RM
- Bianchini L
- Bianco M
- Biebel O
- Bieniek SP
- Bierwagen K
- Biesiada J
- Biglietti M
- Bilokon H
- Bindi M
- Binet S
- Bingul A
- Bini C
- Biscarat C
- Bittner B
- Black CW
- Black JE
- Black KM
- Blair RE
- Blanchard JB
- Blazek T
- Bloch I
- Blocker C
- Blocki J
- Blum W
- Blumenschein U
- Bobbink GJ
- Bobrovnikov VS
- Bocchetta SS
- Bocci A
- Boddy CR
- Boehler M
- Boek J
- Boek TT
- Boelaert N
- Bogaerts JA
- Bogdanchikov A
- Bogouch A
- Bohm C
- Bohm J
- Boisvert V
- Bold T
- Boldea V
- Bolnet NM
- Bomben M
- Bona M
- Boonekamp M
- Bordoni S
- Borer C
- Borisov A
- Borissov G
- Borjanovic I
- Borri M
- Borroni S
- Bortfeldt J
- Bortolotto V
- Bos K
- Boscherini D
- Bosman M
- Boterenbrood H
- Bouchami J
- Boudreau J
- Bouhova-Thacker EV
- Boumediene D
- Bourdarios C
- Bousson N
- Boutouil S
- Boveia A
- Boyd J
- Boyko IR
- Bozovic-Jelisavcic I
- Bracinik J
- Branchini P
- Brandt A
- Brandt G
- Brandt O
- Bratzler U
- Brau B
- Brau JE
- Braun HM
- Brazzale SF
- Brelier B
- Bremer J
- Brendlinger K
- Brenner R
- Bressler S
- Bristow TM
- Britton D
- Brochu FM
- Brock I
- Brock R
- Broggi F
- Bromberg C
- Bronner J
- Brooijmans G
- Brooks T
- Brooks WK
- Brown G
- Bruckman de Renstrom PA
- Bruncko D
- Bruneliere R
- Brunet S
- Bruni A
- Bruni G
- Bruschi M
- Bryngemark L
- Buanes T
- Buat Q
- Bucci F
- Buchanan J
- Buchholz P
- Buckingham RM
- Buckley AG
- Buda SI
- Budagov IA
- Budick B
- Bugge L
- Bulekov O
- Bundock AC
- Bunse M
- Buran T
- Burckhart H
- Burdin S
- Burgess T
- Burke S
- Busato E
- Bussey P
- Buszello CP
- Butler B
- Butler JM
- Buttar CM
- Butterworth JM
- Buttinger W
- Byszewski M
- Büscher V
- Cabrera Urbán S
- Caforio D
- Cakir O
- Calafiura P
- Calderini G
- Calfayan P
- Calkins R
- Caloba LP
- Caloi R
- Calvet D
- Calvet S
- Camacho Toro R
- Camarri P
- Cameron D
- Caminada LM
- Caminal Armadans R
- Campana S
- Campanelli M
- Canale V
- Canelli F
- Canepa A
- Cantero J
- Cantrill R
- Cao T
- Capeans Garrido MD
- Caprini I
- Caprini M
- Capriotti D
- Capua M
- Caputo R
- Cardarelli R
- Carli T
- Carlino G
- Carminati L
- Caron S
- Carquin E
- Carrillo-Montoya GD
- Carter AA
- Carter JR
- Carvalho J
- Casadei D
- Casado MP
- Cascella M
- Caso C
- Castaneda-Miranda E
- Castillo Gimenez V
- Castro NF
- Cataldi G
- Catastini P
- Catinaccio A
- Catmore JR
- Cattai A
- Cattani G
- Caughron S
- Cavaliere V
- Cavalleri P
- Cavalli D
- Cavalli-Sforza M
- Cavasinni V
- Ceradini F
- Cerqueira AS
- Cerri A
- Cerrito L
- Cerutti F
- Cetin SA
- Chafaq A
- Chakraborty D
- Chalupkova I
- Chan K
- Chang P
- Chapleau B
- Chapman JD
- Chapman JW
- Charlton DG
- Chavda V
- Chavez Barajas CA
- Cheatham S
- Chekanov S
- Chekulaev SV
- Chelkov GA
- Chelstowska MA
- Chen C
- Chen H
- Chen S
- Chen X
- Chen Y
- Cheng Y
- Cheplakov A
- Cherkaoui El Moursli R
- Chernyatin V
- Cheu E
- Cheung SL
- Chevalier L
- Chiefari G
- Chikovani L
- Childers JT
- Chilingarov A
- Chiodini G
- Chisholm AS
- Chislett RT
- Chitan A
- Chizhov MV
- Choudalakis G
- Chouridou S
- Chow BK
- Christidi IA
- Christov A
- Chromek-Burckhart D
- Chu ML
- Chudoba J
- Ciapetti G
- Ciftci AK
- Ciftci R
- Cinca D
- Cindro V
- Ciocio A
- Cirilli M
- Cirkovic P
- Citron ZH
- Citterio M
- Ciubancan M
- Clark A
- Clark PJ
- Clarke RN
- Cleland W
- Clemens JC
- Clement B
- Clement C
- Coadou Y
- Cobal M
- Coccaro A
- Cochran J
- Coffey L
- Cogan JG
- Coggeshall J
- Colas J
- Cole B
- Cole S
- Colijn AP
- Collins NJ
- Collins-Tooth C
- Collot J
- Colombo T
- Colon G
- Compostella G
- Conde Muiño P
- Coniavitis E
- Conidi MC
- Consonni SM
- Consorti V
- Constantinescu S
- Conta C
- Conti G
- Conventi F
- Cooke M
- Cooper BD
- Cooper-Sarkar AM
- Copic K
- Cornelissen T
- Corradi M
- Corriveau F
- Cortes-Gonzalez A
- Cortiana G
- Costa G
- Costa MJ
- Costanzo D
- Cottin G
- Courneyea L
- Cowan G
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- Schoening A
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- Shamim M
- Shan LY
- Shank JT
- Shao QT
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- Shatalov PB
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- Sherwood P
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- Shimojima M
- Shin T
- Shiyakova M
- Shmeleva A
- Shochet MJ
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- Siragusa G
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- Skinnari LA
- Skottowe HP
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- Skubic P
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- Slavicek T
- Sliwa K
- Smakhtin V
- Smart BH
- Smestad L
- Smirnov SY
- Smirnov Y
- Smirnova LN
- Smirnova O
- Smith BC
- Smith KM
- Smizanska M
- Smolek K
- Snesarev AA
- Snidero G
- Snow J
- Snow SW
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- Sobie R
- Sodomka J
- Soffer A
- Soh DA
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- Soldatov EY
- Soldevila U
- Solfaroli Camillocci E
- Solodkov AA
- Solovyanov OV
- Solovyev V
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- Spanò F
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- Spiwoks R
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- Stanitzki MM
- Stapnes S
- Starchenko EA
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- Staroba P
- Starovoitov P
- Staszewski R
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- Steinberg P
- Stekl I
- Stelzer B
- Stelzer HJ
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- Stradling AR
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- Ströhmer R
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- Subramaniam R
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- Sundermann JE
- Suruliz K
- Susinno G
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- Suzuki Y
- Suzuki Y
- Svatos M
- Swedish S
- Swiatlowski M
- Sykora I
- Sykora T
- Sánchez J
- Ta D
- Tackmann K
- Taffard A
- Tafirout R
- Taiblum N
- Takahashi Y
- Takai H
- Takashima R
- Takeda H
- Takeshita T
- Takubo Y
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- Talyshev A
- Tam JY
- Tamsett MC
- Tan KG
- Tanaka J
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- Tanasijczuk AJ
- Tani K
- Tannoury N
- Tapprogge S
- Tardif D
- Tarem S
- Tarrade F
- Tartarelli GF
- Tas P
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- Tayalati Y
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- Testa M
- Teuscher RJ
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- Theveneaux-Pelzer T
- Thoma S
- Thomas JP
- Thompson AS
- Thompson EN
- Thompson PD
- Thompson PD
- Thomsen LA
- Thomson E
- Thomson M
- Thong WM
- Thun RP
- Tian F
- Tibbetts MJ
- Tic T
- Tikhomirov VO
- Tikhonov YA
- Timoshenko S
- Tiouchichine E
- Tipton P
- Tisserant S
- Todorov T
- Todorova-Nova S
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- Tojo J
- Tokushuku K
- Tokár S
- Tollefson K
- Tomlinson L
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- Tompkins L
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- Tonoyan A
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- Torrence E
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- Trzebinski M
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- Tsiareshka PV
- Tsionou D
- Tsipolitis G
- Tsiskaridze S
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- Tskhadadze EG
- Tsukerman II
- Tsulaia V
- Tsung JW
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- Tsybychev D
- Tua A
- Tudorache A
- Tudorache V
- Tuggle JM
- Turala M
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- Turk Cakir I
- Turra R
- Tuts PM
- Tykhonov A
- Tylmad M
- Tyndel M
- Tzanakos G
- Uchida K
- Ueda I
- Ueno R
- Ughetto M
- Ugland M
- Uhlenbrock M
- Ukegawa F
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- Undrus A
- Unel G
- Ungaro FC
- Unno Y
- Urbaniec D
- Urquijo P
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- Vachon B
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- Valencic N
- Valentinetti S
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- Valkar S
- Valladolid Gallego E
- Vallecorsa S
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- van der Geer R
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- van der Poel E
- van der Ster D
- van Eldik N
- van Gemmeren P
- Van Nieuwkoop J
- van Vulpen I
- Vanadia M
- Vandelli W
- Vaniachine A
- Vankov P
- Vannucci F
- Vari R
- Varnes EW
- Varol T
- Varouchas D
- Vartapetian A
- Varvell KE
- Vassilakopoulos VI
- Vazeille F
- Vazquez Schroeder T
- Veloso F
- Veneziano S
- Ventura A
- Ventura D
- Venturi M
- Venturi N
- Vercesi V
- Verducci M
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- Vermeulen JC
- Vest A
- Vetterli MC
- Vichou I
- Vickey Boeriu OE
- Vickey T
- Viehhauser GH
- Viel S
- Villa M
- Villaplana Perez M
- Vilucchi E
- Vincter MG
- Vinek E
- Vinogradov VB
- Virzi J
- Vitells O
- Viti M
- Vivarelli I
- Vives Vaque F
- Vlachos S
- Vladoiu D
- Vlasak M
- Vogel A
- Vokac P
- Volpi G
- Volpi M
- Volpini G
- von der Schmitt H
- von Radziewski H
- von Toerne E
- Vorobel V
- Vorwerk V
- Vos M
- Voss R
- Vossebeld JH
- Vranjes Milosavljevic M
- Vranjes N
- Vrba V
- Vreeswijk M
- Vu Anh T
- Vuillermet R
- Vukotic I
- Vykydal Z
- Wagner P
- Wagner W
- Wahlen H
- Wahrmund S
- Wakabayashi J
- Walch S
- Walder J
- Walker R
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- Warburton A
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- Wardrope DR
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- Washbrook A
- Wasicki C
- Watanabe I
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- Waugh BM
- Weber MS
- Webster JS
- Weidberg AR
- Weigell P
- Weingarten J
- Weiser C
- Wells PS
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- Wendland D
- Weng Z
- Wengler T
- Wenig S
- Wermes N
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- Werner P
- Werth M
- Wessels M
- Wetter J
- Weydert C
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- Wiedenmann W
- Wielers M
- Wienemann P
- Wiglesworth C
- Wiik-Fuchs LA
- Wijeratne PA
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- Wildt MA
- Wilhelm I
- Wilkens HG
- Will JZ
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- Willis W
- Willocq S
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- Wilson JA
- Wilson MG
- Wingerter-Seez I
- Winkelmann S
- Winklmeier F
- Wittgen M
- Wittig T
- Wittkowski J
- Wollstadt SJ
- Wolter MW
- Wolters H
- Wong WC
- Wooden G
- Wosiek BK
- Wotschack J
- Woudstra MJ
- Wozniak KW
- Wraight K
- Wright M
- Wrona B
- Wu SL
- Wu X
- Wu Y
- Wulf E
- Wynne BM
- Xella S
- Xiao M
- Xie S
- Xu C
- Xu D
- Xu L
- Yabsley B
- Yacoob S
- Yamada M
- Yamaguchi H
- Yamamoto A
- Yamamoto K
- Yamamoto S
- Yamamura T
- Yamanaka T
- Yamauchi K
- Yamazaki T
- Yamazaki Y
- Yan Z
- Yang H
- Yang H
- Yang UK
- Yang Y
- Yang Z
- Yanush S
- Yao L
- Yasu Y
- Yatsenko E
- Ye J
- Ye S
- Yen AL
- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
- Yoshihara K
- Young C
- Young CJ
- Youssef S
- Yu D
- Yu DR
- Yu J
- Yu J
- Yuan L
- Yurkewicz A
- Zabinski B
- Zaidan R
- Zaitsev AM
- Zambito S
- Zanello L
- Zanzi D
- Zaytsev A
- Zeitnitz C
- Zeman M
- Zemla A
- Zenin O
- Zeniš T
- Zerwas D
- Zevi Della Porta G
- Zhang D
- Zhang H
- Zhang J
- Zhang L
- Zhang X
- Zhang Z
- Zhao L
- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zibell A
- Zieminska D
- Zimin NI
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zitoun R
- Zivković L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- American Physical Society
- Publication date
- 01/01/2012
- Field of study
Two-particle correlations in relative azimuthal angle (Δϕ) and pseudorapidity (Δη) are measured in √sNN=5.02 TeV p+Pb collisions using the ATLAS detector at the LHC. The measurements are performed using approximately 1 μb-1 of data as a function of transverse momentum (pT) and the transverse energy (ΣETPb) summed over 3.1<η<4.9 in the direction of the Pb beam. The correlation function, constructed from charged particles, exhibits a long-range (2<|Δη|<5) “near-side” (Δϕ∼0) correlation that grows rapidly with increasing ΣETPb. A long-range “away-side” (Δϕ∼π) correlation, obtained by subtracting the expected contributions from recoiling dijets and other sources estimated using events with small ΣETPb, is found to match the near-side correlation in magnitude, shape (in Δη and Δϕ) and ΣETPb dependence. The resultant Δϕ correlation is approximately symmetric about π/2, and is consistent with a dominant cos2Δϕ modulation for all ΣETPb ranges and particle pT
Search for high-mass resonances decaying to dilepton final states in pp collisions at s√=7 TeV with the ATLAS detector
- Author
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- Abajyan T
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdinov O
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- Zhemchugov A
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- Zobernig G
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- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- Springer
- Publication date
- 23/11/2012
- Field of study
The ATLAS detector at the Large Hadron Collider is used to search for high-mass resonances decaying to an electron-positron pair or a muon-antimuon pair. The search is sensitive to heavy neutral Z′ gauge bosons, Randall-Sundrum gravitons, Z * bosons, techni-mesons, Kaluza-Klein Z/γ bosons, and bosons predicted by Torsion models. Results are presented based on an analysis of pp collisions at a center-of-mass energy of 7 TeV corresponding to an integrated luminosity of 4.9 fb−1 in the e + e − channel and 5.0 fb−1 in the μ + μ −channel. A Z ′ boson with Standard Model-like couplings is excluded at 95 % confidence level for masses below 2.22 TeV. A Randall-Sundrum graviton with coupling k/MPl=0.1 is excluded at 95 % confidence level for masses below 2.16 TeV. Limits on the other models are also presented, including Technicolor and Minimal Z′ Models
Search for R-parity-violating supersymmetry in events with four or more leptons in sqrt(s) =7 TeV pp collisions with the ATLAS detector
- Author
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- Yang Z
- Yanush S
- Yao L
- Yao Y
- Yasu Y
- Smit GVY
- Ye J
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- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
- Yoshihara K
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- Young CJ
- Youssef S
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- Yurkewicz A
- Zabinski B
- Zaidan R
- Zaitsev AM
- Zajacova Z
- Zanello L
- Zanzi D
- Zaytsev A
- Zeitnitz C
- Zeman M
- Zemla A
- Zendler C
- Zenin O
- Zenis T
- Zinonos Z
- Zerwas D
- della Porta GZ
- Zhang D
- Zhang H
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- Zhang X
- Zhang Z
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- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
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- Zhou Y
- Zhu CG
- Zhu H
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- Zhu Y
- Zhuang X
- Zhuravlov V
- Zibell A
- Zieminska D
- Zimin NI
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Collaboration ATLAS
- Publication venue
- Springer Verlag
- Publication date
- 01/01/2008
- Field of study
A search for new phenomena in final states with four or more leptons (electrons or muons) is presented. The analysis is based on 4.7 fb−1 of s=7TeV proton-proton collisions delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in two signal regions: one that requires moderate values of missing transverse momentum and another that requires large effective mass. The results are interpreted in a simplified model of R-parity-violating supersymmetry in which a 95% CL exclusion region is set for charged wino masses up to 540 GeV. In an R-parity-violating MSUGRA/CMSSM model, values of m 1/2 up to 820 GeV are excluded for 10 < tan β < 40
Search for the neutral Higgs bosons of the minimal supersymmetric standard model in pp collisions at root s=7 TeV with the ATLAS detector
- Author
- Aad G
- Abajyan T
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdinov O
- Abi B
- Abolins M
- AbouZeid OS
- Abramowicz H
- Abreu H
- Acharya BS
- Adam ER
- Adamczyk L
- Adams DL
- Addy TN
- Adelman J
- Adomeit S
- Adragna P
- Adye T
- Aesky S
- Agar-Savedra JA
- Agustoni M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akesson TPA
- Akimoto G
- Akimov AV
- Alam MA
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Allbrooke BMM
- Allison LJ
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alonso F
- Altheimer A
- Alviggi MG
- Amako K
- Amelung C
- Ammosov VV
- Amor Dos Santos SP
- Amorim A
- Amoroso S
- Amram N
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anderson KJ
- Andreazza A
- Andrei V
- Andrieux M-L
- Anduaga XS
- Angelidakis S
- Anger P
- Angerami A
- Anghinolfi F
- Anh TV
- Anisenkov A
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
- Antonov A
- Antos J
- Anulli F
- Aoki M
- Aoun S
- Apolle R
- Arabidze G
- Aracena I
- Arai Y
- Aranda CP
- Arce ATH
- Arfaoui S
- Arguin J-F
- Argyropoulos S
- Arik E
- Arik M
- Armbruster AJ
- Arnaez O
- Arnal V
- Artamonov A
- Artoni G
- Arutinov D
- Asai S
- Ask S
- Asman B
- Asquith L
- Assamagan K
- Astbury A
- Atkinson M
- Aubert B
- Auge E
- Augsten K
- Aurousseau M
- Avolio G
- Axen A
- Azuelos G
- Azuma Y
- Baak MA
- Baccaglioni G
- Bacci C
- Bach AM
- Bachacou H
- Bachas K
- Backes M
- Backhaus M
- Badescu E
- Bagnaia P
- Bai Y
- Bailey DC
- Bain T
- Baines JT
- Baker OK
- Baker S
- Balek P
- Banas E
- Banerjee P
- Banerjee S
- Banfi D
- Bangert A
- Bansal V
- Bansil HS
- Barak L
- Baranov SP
- Barber T
- Barberio EL
- Barberis D
- Barbero N
- Bardin DY
- Barillari T
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- Barnett BM
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- Barojas CAC
- Baroncelli A
- Barone G
- Barr AJ
- Barreiro F
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- Bartoldus R
- Barton AE
- Bartsch V
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- Publication venue
- Publication date
- 01/02/2013
- Field of study
A search for neutral Higgs bosons of the Minimal Supersymmetric Standard Model (MSSM) is reported. The analysis is based on a sample of proton-proton collisions at a centre-of-mass energy of 7TeV recorded with the ATLAS detector at the Large Hadron Collider. The data were recorded in 2011 and correspond to an integrated luminosity of 4.7 fb-1 to 4.8 fb-1. Higgs boson decays into oppositely-charged muon or τ lepton pairs are considered for final states requiring either the presence or absence of b-jets. No statistically significant excess over the expected background is observed and exclusion limits at the 95% confidence level are derived. The exclusion limits are for the production cross-section of a generic neutral Higgs boson, φ, as a function of the Higgs boson mass and for h/A/H production in the MSSM as a function of the parameters mA and tan β in the mhmax scenario for mA in the range of 90GeV to 500 GeV. Copyright CERN
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