3 research outputs found

    Intersecting Homeliness: Vietnamese Australian Reflections of a Suburban Home (Strathfield, NSW)

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    In year 2013, I lived in Vietnam. Once a year, the Vietnamese people have a particular tradition called khom đáș„t, where the people set out a guest table filled with delicious feast of food and paper clothing, shoes, accessories and money for the spirits of the house. Khom in khom đáș„t means a set of rituals or prayer to bow down and pay respect. Đáș„t means land. It is a ritual which acknowledges the spirits within the home and the agency these spirits have to the home. There would be separate rituals for different types of spirits and incense would burn as an offering to various places. For example, an incense and food offering would be on an alter directly above the fire stove in the kitchen to be grateful to the fire spirit of the home. There is a belief that if the fire spirit gets angry, the spirit may be a danger to the family. The spirit has the agency and a power over the home. It is a ritual to recognise that a home has its ghosts, its history and its spirits that reside long before the current people residents and that they have the power to protect or destroy. Mostly, it is to recognaise that land and place is not to be owned, and matters such as fire or water or wood is not mere commodities. Rather, these materialities are living and only would be at our disposal to help us when they given the respect and recognition that they are living and are powerful agents.Within the Vietnamese language, there is no specific word for differentiate ‘home’ and ‘house’ but rather, use the word ‘house’ to mean both the building and the home – nhĂ  (Rather then state, ‘I go home’ one states literally, ‘I return to the house’ – TĂŽi về nhĂ ). To state house rather than home could mean that home is not to be possessed but rather, has it’s own agency, vitality and spirit.With this in mind, I will tell you about a particular uncanny phenomenon that has happened in my family home in Strathfield (a loved family home where my family still resides in) that has happened 10 years ago and has not escaped the memories of any of us. I hope to capture, in a self-reflexive way, the merging of the past and the present within the Vietnamese migrant experience living in the Australian landscape, with its dark history of the forced displacement of Indigenous peoples. I wish to mourn and acknowledge that the land that has given my refugee family opportunity to begin life safely and freely, and my birthplace is a stolen land. And that we are always both grateful and in mourning with our homeland

    The collagen suprafamily : from biosynthesis to advanced biomaterial development

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    Biomimetic microenvironments are key components to successful cell culture and tissue engineering in vitro. One of the most accurate biomimetic microenvironments is that made by the cells themselves. Cell-made microenvironments are most similar to the in vivo state as they are cell-specific and produced by the actual cells which reside in that specific microenvironment. However, cell-made microenvironments have been challenging to re-create in vitro due to the lack of extracellular matrix composition, volume and complexity which are required. By applying macromolecular crowding to current cell culture protocols, cell-made microenvironments, or cell-derived matrices, can be generated at significant rates in vitro. In this review, we will examine the causes and effects of macromolecular crowding and how it has been applied in several in vitro systems including tissue engineering

    The Collagen Suprafamily: From Biosynthesis to Advanced Biomaterial Development

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    Collagen is the oldest and most abundant extracellular matrix protein that has found many applications in food, cosmetic, pharmaceutical, and biomedical industries. First, an overview of the family of collagens and their respective structures, conformation, and biosynthesis is provided. The advances and shortfalls of various collagen preparations (e.g., mammalian/marine extracted collagen, cell-produced collagens, recombinant collagens, and collagen-like peptides) and crosslinking technologies (e.g., chemical, physical, and biological) are then critically discussed. Subsequently, an array of structural, thermal, mechanical, biochemical, and biological assays is examined, which are developed to analyze and characterize collagenous structures. Lastly, a comprehensive review is provided on how advances in engineering, chemistry, and biology have enabled the development of bioactive, 3D structures (e.g., tissue grafts, biomaterials, cell-assembled tissue equivalents) that closely imitate native supramolecular assemblies and have the capacity to deliver in a localized and sustained manner viable cell populations and/or bioactive/therapeutic molecules. Clearly, collagens have a long history in both evolution and biotechnology and continue to offer both challenges and exciting opportunities in regenerative medicine as nature's biomaterial of choice.This work forms part of the Teagasc Walsh Fellowship (grant award number: 2014045) and the ReValueProtein Research Project (grant award number: 11/F/043) supported by the Department of Agriculture, Food and the Marine (DAFM) under the National Development Plan 2007–2013 funded by the Irish Government. This work has also been supported from the: Health Research Board, Health Research Awards Programme (grant agreement number: HRA_POR/2011/84); Science Foundation Ireland, Career Development Award Programme (grant agreement number: 15/CDA/3629); Science Foundation Ireland and the European Regional Development Fund (grant agreement number: 13/RC/2073); College of Engineering and Informatics, National University of Ireland Galway; EU FP7/2007-2013, NMP award, Green Nano Mesh Project (grant agreement number: 263289); EU FP7/2007-2013, Health award, Neurograft Project (grant agreement number: 304936); EU H2020, ITN award, Tendon Therapy Train Project (grant agreement number: 676338); National University of Singapore Tissue Engineering Programme (NUSTEP). The authors would like to thank M Doczyk, E Collin, W Daly, M Abu-Rub, D Thomas, S Browne, C Tapeinos, A Satyam and D Cigognini for their help in producing the figures. A.S., L.M.D., Z.W., N.S., A.K., R.N.R., A.M.M., A.P., M.R., and D.I.Z. have no competing interests. Y.B. is an employee of Sofradim Production – A Medtronic Company. D.I.Z would like to dedicate the manuscript to A.G.Z. who left and A.D.Z. who camepeer-reviewe
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