An experiment for the measurement of the bound-beta decay of the free neutron

The hyperfine-state population of hydrogen after the bound-beta decay of the neutron directly yields the neutrino left-handedness or a possible right-handed admixture and possible small scalar and tensor contributions to the weak force. Using the through-going beam tube of a high-flux reactor, a background free hydrogen rate of ca. 3 s$^{-1}$ can be obtained. The detection of the neutral hydrogen atoms and the analysis of the hyperfine states is accomplished by Lamb shift source type quenching and subsequent ionization. The constraints on the neutrino helicity and the scalar and tensor coupling constants of weak interaction can be improved by a factor of ten.Comment: 9 pages, 5 figures. Submitted to EPJ

Enhancing competitive island cooperative neuro - evolution through backpropagation for pattern classification

Cooperative coevolution is a promising method for training neural networks which is also known as cooperative neuro-evolution. Cooperative neuro-evolution has been used for pattern classification, time series prediction and global optimisation problems. In the past, competitive island based cooperative coevolution has been proposed that employed different instances of problem decomposition methods for competition. Neuro-evolution has limitations in terms of training time although they are known as global search methods. Backpropagation algorithm employs gradient descent which helps in faster convergence which is needed for neuro-evolution. Backpropagation suffers from premature convergence and its combination with neuro-evolution can help eliminate the weakness of both the approaches. In this paper, we propose a competitive island cooperative neuro-evolutionary method that takes advantage of the strengths of gradient descent and neuro-evolution. We use feedforward neural networks on benchmark pattern classification problems to evaluate the performance of the proposed algorithm. The results show improved performance when compared to related methods

R&D consortia as boundary organisations: Misalignment and asymmetry of boundary management

The paper presents a qualitative multiple case study of three multilateral public-private R&D consortia representing different industrial sectors. Using the practice-based view as a theoretical lens, we explore the interplay between the deliberate and emergent practices of boundary management across the following three dimensions: (1) Boundary bridging focus; (2) boundary crossing arrangements; and (3) collaborative governance arrangements. Drawing on interviews, documentary analysis and observational data, we describe the misalignment between the deliberate and emergent aspects of boundary management, which can be caused by the funders' reporting requirements, power differentials between collaborators and lack of contextual understanding. These factors, accompanied by path-dependency and confidentiality issues, may result in asymmetrical boundary management, whereby a selective focus on a specific boundary (or set of boundaries) combined with an unequal development of boundary bridges within the collaboration may lead to the crossing of some boundaries being prioritised at the expense of others

Food and nutrition literacy status and its correlates in Iranian senior high-school students

Background: Planning interventions to promote food and nutrition literacy (FNL) require a better understanding of the FNL status of the target group and its correlates. Aims: This study aimed to examine the FNL status and its determinants in Iranian senior high-school students. Methods: In this cross-sectional study, FNL and its components (food and nutrition knowledge, functional skills, interactive skills, advocacy, critical analysis of information, and food label reading skill) were evaluated by a locally designed and validated, self-administered questionnaire. Besides, socioeconomic, demographic, anthropometric measures, as well as academic performance of 626 senior high-school students were assessed. Results: The mean ± SD of the total FNL score (within potential range of 0 to 100) was 52.1 ± 10.96, which is below the minimum adequate level of 60. The probability of high FNL knowledge score was significantly higher among students who majored in Natural Sciences (OR = 1.73, CI = 1.09�2.75), had better school performance (OR = 1.13, CI = 1.06�1.20) and higher SES score (OR = 1.20, CI = 1.01�1.44). The score for food label reading was significantly lower in girls (OR = 0.45, CI = 0.31�0.67), while those who had a family member with the nutrition-related disease were more likely to have a higher score of food label reading skill (OR = 1.48, CI = 1.01�1.64). Conclusion: The level of FNL in senior high-school students in Tehran was relatively low. These findings have key messages for the education system and curriculum designers to have more consideration for food and nutrition-related knowledge and skills in schools. © 2021, The Author(s)

De novo assembly and phasing of dikaryotic genomes from two isolates of puccinia coronata f. Sp. avenae, the causal agent of oat crown rust

Oat crown rust, caused by the fungus Pucinnia coronata f. sp. avenae, is a devastating disease that impacts worldwide oat production. For much of its life cycle, P. coronata f. sp. avenae is dikaryotic, with two separate haploid nuclei that may vary in virulence genotype, highlighting the importance of understanding haplotype diversity in this species. We generated highly contiguous de novo genome assemblies of two P. coronata f. sp. avenae isolates, 12SD80 and 12NC29, from long-read sequences. In total, we assembled 603 primary contigs for 12SD80, for a total assembly length of 99.16 Mbp, and 777 primary contigs for 12NC29, for a total length of 105.25 Mbp; approximately 52% of each genome was assembled into alternate haplotypes. This revealed structural variation between haplotypes in each isolate equivalent to more than 2% of the genome size, in addition to about 260,000 and 380,000 heterozygous single-nucleotide polymorphisms in 12SD80 and 12NC29, respectively. Transcript-based annotation identified 26,796 and 28,801 coding sequences for isolates 12SD80 and 12NC29, respectively, including about 7,000 allele pairs in haplotype-phased regions. Furthermore, expression profiling revealed clusters of coexpressed secreted effector candidates, and the majority of orthologous effectors between isolates showed conservation of expression patterns. However, a small subset of orthologs showed divergence in expression, which may contribute to differences in virulence between 12SD80 and 12NC29. This study provides the first haplotype-phased reference genome for a dikaryotic rust fungus as a foundation for future studies into virulence mechanisms in P. coronata f. sp. avenae.This work was funded by the USDA-ARS and the University of Minnesota Standard Cooperative Agreement (grant 3002-11031-00053115 shared by S.F.K. and M.F.), the University of Minnesota Experimental Station USDA-NIFA Hatch/Figueroa project MIN22-058, and an Organization for Economic Cooperation and Development Fellowship to M.F. M.E.M. was partially supported by a USDA-NIFA Postdoctoral Fellowship Award (2017-67012-26117). J.S. was supported by an OCE Postdoctoral Fellowship. R.F.P. receives funding from the Australian Grains Research Development Corporation (grant US00067). J.M.P. was supported by the Northern Research Station of the USDA Forest Service

Accelerating Innovation in the Creation of Biovalue : The Cell and Gene Therapy Catapult

The field of regenerative medicine (RM) has considerable therapeutic promise that is proving difficult to realize. As a result, governments have supported the establishment of intermediary agencies to “accelerate” innovation. This paper examines in detail one such agency, the UK's Cell and Gene Therapy Catapult (CGTC). We describe CGTC’s role as an accelerator agency and its value-narrative, which combines both “health and wealth.” Drawing on the notion of socio-technical imaginaries, we unpack the tensions within this narrative and its instantiation as the CGTC cell therapy infrastructure is built and engages with other agencies, some of which have different priorities and roles to play within the RM field

The lives and deaths of positrons in the interstellar medium

We reexamine in detail the various processes undergone by positrons in the ISM from their birth to their annihilation using the most recent results of positron interaction cross sections with H, H2 and He. The positrons' lives are divided into two phases: the 'in-flight' phase and the thermal phase. The first phase is treated with a Monte Carlo simulation that allows us to determine the fraction of positrons that form positronium and annihilate as well as the characteristics of the annihilation emission as a function of the medium conditions. The second phase is treated with a binary reaction rate approach, with cross sections adopted from experimental measurement or theoretical calculations. An extensive search and update of the knowledge of positron processes was thus undertaken. New reaction rates and line widths have been obtained. We investigate the treatment of the complicated interactions between positrons and interstellar dust grains. New reaction rates and widths of the line resulting from the annihilation inside and outside of the grain have been obtained. The final results of our calculations showed that dust is only important in the hot phase of the ISM, where it dominates all other processes. Combining the new calculations, we have constructed annihilation spectra for each phase of the ISM, considering various grain contents, as well as an overall combined spectrum for the ISM as a whole.Comment: 16 pages, 6 figures. accepted in Astronomy and Astrophysic

The Household Water Insecurity Experiences (HWISE) Scale: comparison scores from 27 sites in 22 countries

Abstract Household survey data from 27 sites in 22 countries were collected in 2017–2018 in order to construct and validate a cross-cultural household-level water insecurity scale. The resultant Household Water Insecurity Experiences (HWISE) scale presents a useful tool for monitoring and evaluating water interventions as a complement to traditional metrics used by the development community. It can also help track progress toward achievement of Sustainable Development Goal 6 ‘clean water and sanitation for all’. We present HWISE scale scores from 27 sites as comparative data for future studies using the HWISE scale in low- and middle-income contexts. Site-level mean scores for HWISE-12 (scored 0–36) ranged from 1.64 (SD 4.22) in Pune, India, to 20.90 (7.50) in Cartagena, Colombia, while site-level mean scores for HWISE-4 (scored 0–12) ranged from 0.51 (1.50) in Pune, India, to 8.21 (2.55) in Punjab, Pakistan. Scores tended to be higher in the dry season as expected. Data from this first implementation of the HWISE scale demonstrate the diversity of water insecurity within and across communities and can help to situate findings from future applications of this tool