Outline and Benefits of Multi-Modality Intraoperative Neuromonitoring in Spine Surgery Explained with a Case Report

The major complication of any form of spinal surgery is neurological insult which can result in serious post-operative sensory or motor deficit. Intraoperative neuromonitoring has evolved to identify and help to avert these insults through real time assessment of the spinal cord function. This paper is to provide an outline of the major modalities utilised in Intraoperative neuromonitoring during spine surgery, how they help in identifying neurological insults and aid in reducing post operative deficits, all explained through a case report

Light Fedility (Li-Fi) - An Emerging Era of Wireless Data Communication and its Applications

These days, internet has turned out to be major demand that people are in seek of Wi-Fi hotspots (internet providers). Li-Fi offers transmission of information through visible by transferring information via an LED light bulb that diverges in concentration quicker than individual eye can go after. The term Li-Fi states to VLC(visible light communication) technology that utilizes as standard to carry speedy interaction in a way comparable to Wi-Fi. Li-Fi supplies superior efficiency, security, bandwidth and availability than Wi-Fi. This paper offer a brief summary on Li-Fi technology, its applications, potential and advantages

MiR-150, A Novel and Potent Regulator for MLL-AF9 Leukemic Stem Cells

MicroRNAs (miRNAs) are a class of short, non-coding RNAs that post-transcriptionally regulate gene expression, particularly in cancers. MicroRNA-150 has been proven as a critical regulatory for normal hematopoiesis and a potent inhibitor of MLL-AF9 leukemias. To understand the potential mechanism of how miR-150 suppresses MLL-AF9 leukemia through the regulation of leukemic stem cells (LSCs), the gain- and loss-of miR-150 strategies were adopted on an established MLL-AF9 expressing cell line. Gain-of-function will be carried out with miR-150 overexpressing construct and loss-of-function of miR-150 will be performed by utilizing a newly established sponge system to achieve chromosomal recombination. The effect of miR-150 on MLL-AF9 LSCs will evaluated using multiple methodologies

One-step transformation of 2-oxa-3-azabicyclo[2.2.1]hept-5-ene and methyl 2,3-diazabicyclo[2.2.1]heptane-2-carboxylate to ion uptake systems

Linker generated duplexes of the title compounds- prepared from cyclopentadiene- with possibility for positioning of four oxygen in the cavity, are shown to be excellent ion uptake systems. Mass spectrometric doping studies with lithium, sodium, potassium and silver ions, show a clear preference for lithium complexation. The lithium salts of the best examples have been prepared and characterized

Geographic Variance in Water Pollution in Illinois

Water pollution negatively affects lakes, rivers, drinking water, oceans, and seas all over the world. The pollution of this finite resource harms the environment and the health of humans who drink the water. Illinois is home to over 119,000 miles of streams, 900 miles of large rivers, and more than 91,000 freshwater lakes and ponds. However, due to industrial and agricultural activities in the past and the present day, many of the bodies of water have been polluted in varying levels throughout the state. Our project compares the geographic distribution of pollution in Illinois waterways to the geographic distribution of human related factors, such as the spread of utility plants, commercial farms, and human population centers throughout Illinois. We quantify the pollution of waterways by examining the pH, temperature, and the prevalence of various compounds, such as nitrogen based compounds and orthophosphates, in different waterways. We then analyze patterns in the data to understand which human related factors have the highest effects on water pollution in Illinois. Understanding the effects that specific types of man-made activities can have on water pollution allows efforts to be made that efficiently limit water pollution by targeting the pollution sources that contribute the most to water pollution in Illinois. Analyzing the sources of water pollution also spreads awareness of the causes of this ecological problem, which is beneficial to limiting water pollution

FORMULATION AND EVALUATION OF ORODISPERSIBLE TABLETS OF LAMOTRIGINEUSING DISCRETE SUPER DISINTEGRANTS AND COPROCESSED EXCIPIENTS

Objective: The present study was designed to formulate and evaluate the orodispersible tablets of lamotrigine after enhancing its solubility. Methods: Lamotrigine was made into an inclusion complex with eudragit E 100 my kneading and mass extrusion method and later this mixture is compressed into orodispersible tablet using various super disintegrants and co-processed excipients to reduce the disintegration time for providing prompt action through rapid drug release. Results: Lamotrigine ODTs containing F-melt (F1-3%, F2-5%) dispersed in lesser time of (9±0.11) and (21±0.58) compared to formulations with polyplasdone XL-10 and primellose as super disintegrants respectively with F1 showing short wetting time. The water absorption was also was found to be more for formulation with 3% F-Melt. Conclusion: Lamotrigine orodispersible tablets were prepared by direct compression technique by using 3% and 5% of three super disintegrants (f-melt, primellose and polyplasdone XL-10). Disintegration time of F1 (3% f-melt) formulation was found to be least (7 sec)

Simulating FAS-induced apoptosis by using P systems

In contrast to differential equations, P systems are an unconven- tional model of computation which takes into consideration the discrete character of the quantity of components and the inherent randomness that exists in biological phenomena. The key feature of P systems is their compartmentalised structure which represents the heterogeneity of the structural organisation of the cells, and where one can take into account the role played by membranes in the functioning of the system, for example signalling at the cell surface [13], selective uptake of sub- stances from the media [14], diffusion across different compartments [15], etc. We show here that P systems can be a reliable tool for Systems Biology and could even outperform in some cases the current simu- lation techniques based on differential equations. We will also use a strategy based on the well known Gillespie algorithm [4] but running on more than one compartment called Multi-compartmental Gillespie Algorithm [13]

COMPOSITIONS AND COMPOUNDS FOR USE AS MOLECULAR ADJUVANT FOR A NCOTINE WACCNE

Compounds are disclosed comprising molecular adjuvants having an antigen presenting cell-targeting ligand linked to a nicotine hapten. Methods are disclosed for employing the compounds as a nicotine vaccine for treatment or prevention of nicotine addiction

Probabilistic Guarded P Systems, A New Formal Modelling Framework

Multienvironment P systems constitute a general, formal framework for modelling the dynamics of population biology, which consists of two main approaches: stochastic and probabilistic. The framework has been successfully used to model biologic systems at both micro (e.g. bacteria colony) and macro (e.g. real ecosystems) levels, respectively. In this paper, we extend the general framework in order to include a new case study related to P. Oleracea species. The extension is made by a new variant within the probabilistic approach, called Probabilistic Guarded P systems (in short, PGP systems). We provide a formal definition, a simulation algorithm to capture the dynamics, and a survey of the associated software.Ministerio de Economía y Competitividad TIN2012- 37434Junta de Andalucía P08-TIC-0420