Memory for spatial locations in a patient with near space neglect and optic ataxia: Involvement of the occipitotemporal stream

Previous studies suggested that the occipitoparietal stream orients attention toward the near/lower space and is involved in immediate reaching, whereas the occipitotemporal stream orients attention toward the far/upper space and is involved in delayed reaching. In the present study, we investigated the role of the occipitotemporal stream in attention orienting and delayed reaching in a patient (GP) with bilateral damage to the occipitoparietal areas and optic ataxia. GP and healthy controls took part in three experiments. In the experiment 1, the participants bisected lines oriented along radial, vertical, and horizontal axes. GP bisected radial lines farther, and vertical lines more above, than the controls, consistent with an attentional bias toward the far/upper space and near/lower space neglect. The experiment 2 consisted of two tasks: (1) an immediate reaching task, in which GP reached target locations under visual control and (2) a delayed visual reaching task, in which GP and controls were asked to reach remembered target locations visually presented. We measured constant and variable distance and direction errors. In immediate reaching task, GP accurately reached target locations. In delayed reaching task, GP overshot remembered target locations, whereas the controls undershot them. Furthermore, variable errors were greater in GP than in the controls. In the experiment 3, GP and controls performed a delayed proprioceptive reaching task. Constant reaching errors did not differ between GP and the controls. However, variable direction errors were greater in GP than in the controls. We suggest that the occipitoparietal damage, and the relatively intact occipitotemporal region, produced in GP an attentional orienting bias toward the far/upper space (experiment 1). In turns, the attentional bias selectively shifted toward the far space remembered visual (experiment 2), but not proprioceptive (experiment 3), target locations. As a whole, these findings further support the hypothesis of an involvement of the occipitotemporal stream in delayed reaching. Furthermore, the observation that in both delayed reaching tasks the variable errors were greater in GP than in the controls suggested that in optic ataxia is present not only a visuo- but also a proprioceptivo-motor integration deficit

Design of power-blocks for medium-scale supercritical carbon dioxide plants

For power production, the emerging technologies of supercritical carbon dioxide (S-CO2) cycles show potential advantages if compared to conventional plants. The current bottleneck in exploiting such cycles is the development of novel components such as turbomachines and heat-exchangers. This paper focuses on the layout arrangement and machinery design of a novel power block for a 10 to 15 MW supercritical carbon dioxide plant. The applied design procedure involves 0D and 1D models implemented using an in-house Fortran code, and 3D computational fluid dynamics (CFD) analyses using ANSYS-CFX. Novel configurations of the power block were designed, starting with the same primary thermal source. At nominal conditions, expected overall output powers from 13.2 to 16.2 MW were found. Finally, some qualitative considerations were included in the discussion to compare the analysed arrangements

Assessment of energy, mobility, waste, and water management on Italian small islands

Small islands are recognized for their vulnerability to climate change. In this context, mitigation and adaptation policies are needed, but the ecological transition must be based on data. This study aims to assess the level of sustainability reached by 26 of the inhabited Italian small islands; it collects and analyzes the data and initiatives on the energy, mobility, waste, and water sectors and discusses the islands’ steps toward sustainability. The findings show that 18 of the 26 islands are not interconnected with the national grid and that the renewable sources cover less than 5% of the energy demand on 25 of the 26 islands. The number per capita of private vehicles reaches 90 cars per 100 inhabitants on three islands. The average of the separate collection of waste on the islands is 52%, which is far from the minimum recommended threshold of 65%. Pipelines or tankers on 17 of the 26 islands guarantee the water supply, and desalination plants are still not the rule, while the presence of wastewater treatment has been detected on 12 islands, and it often provides only partial treatment. An ambitious multi-stakeholder sustainability plan for each island should be developed to overcome the typical barriers of the island and to increase the building capacity in order to use economic incentives for that goal

Secondary SOLID Tumors after Allogeneic STEM CELL Transplantation: A CROSS-Sectional Evaluation in 260 Adults at 1-Year Follow-up

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An Exploratory Analysis of Factors Associated with Health-Related Physical Fitness in Adolescents. The ASSO Project

Monitoring physical fitness (fitness) and identifying, since the beginning, possible determinants in youth could be useful to preserve health and avoid morbidities in adulthood. The main objective of this study is to provide details on the fitness levels of a sample of adolescents living in the Southern area of Italy and describe its associations with biological/genetic, socio-cultural/environmental, and lifestyle (physical activity/sedentariness, alcohol/smoking, meal patterns/habits) factors. The study was conducted within the Adolescence Surveillance System for Obesity Prevention (ASSO) project, funded by the Italian Ministry of Health and examining adolescents\u2019 lifestyle in relation to obesity. Fitness measures were collected through the ASSO-fitness tests battery (FTB) and examined in relation to 79 selected possible influencing factors, which were collected through a web-based questionnaire included in the ASSO-NutFit software. Logistic regression analyses were performed to assess associations, with ORs and 95% CIs estimated as crude and adjusted. A total of 919 participants were initially recruited, but fitness data were collected for 544 students aged 13\u201319 (68% M, 32% F). Fitness level was low for 14.2% of the students, medium for 67.8%, and high for 18.0%. The independent determinants of low physical fitness in our sample of adolescents were included in the biological/genetic and physical activity/sedentariness dimensions: female gender (Adj OR 8.33, CI 2.08\u201333.33), obesity (Adj OR 1.97, CI 1.10\u20139.22), practicing sport less than 3 h/week (Adj OR 6.09, CI 1.63\u201322.72), practicing sport with strength/speed as prevalent biomotor ability (Adj OR 8.97, CI 1.43\u201356.19), using PC/internet for more than 3 h/day (Adj OR 4.46, CI 1.17\u201316.98). Drinking alcohol was instead a protective factor. This study confirms that females and obese individuals need more attention in the interventions aimed at increasing fitness levels. It suggests that local actions should be implemented with the aim of increasing sport practices and reducing sedentary time spent in front of PC/internet. The focus should be particularly addressed to sports with strength or speed as dominant biomotor abilities

Memory for Spatial Locations in a Patient with Near Space Neglect and Optic Ataxia: Involvement of the Occipitotemporal Stream

Previous studies suggested that the occipitoparietal stream orients attention toward the near/lower space and is involved in immediate reaching, whereas the occipitotemporal stream orients attention toward the far/upper space and is involved in delayed reaching. In the present study, we investigated the role of the occipitotemporal stream in attention orienting and delayed reaching in a patient (GP) with bilateral damage to the occipitoparietal areas and optic ataxia. GP and healthy controls took part in three experiments. In the experiment 1, the participants bisected lines oriented along radial, vertical, and horizontal axes. GP bisected radial lines farther, and vertical lines more above, than the controls, consistent with an attentional bias toward the far/upper space and near/lower space neglect. The experiment 2 consisted of two tasks: (1) an immediate reaching task, in which GP reached target locations under visual control and (2) a delayed visual reaching task, in which GP and controls were asked to reach remembered target locations visually presented. We measured constant and variable distance and direction errors. In immediate reaching task, GP accurately reached target locations. In delayed reaching task, GP overshot remembered target locations, whereas the controls undershot them. Furthermore, variable errors were greater in GP than in the controls. In the experiment 3, GP and controls performed a delayed proprioceptive reaching task. Constant reaching errors did not differ between GP and the controls. However, variable direction errors were greater in GP than in the controls. We suggest that the occipitoparietal damage, and the relatively intact occipitotemporal region, produced in GP an attentional orienting bias toward the far/upper space (experiment 1). In turns, the attentional bias selectively shifted toward the far space remembered visual (experiment 2), but not proprioceptive (experiment 3), target locations. As a whole, these findings further support the hypothesis of an involvement of the occipitotemporal stream in delayed reaching. Furthermore, the observation that in both delayed reaching tasks the variable errors were greater in GP than in the controls suggested that in optic ataxia is present not only a visuo- but also a proprioceptivo-motor integration deficit

Design of power-blocks for medium-scale supercritical carbon dioxide plants

For power production, the emerging technologies of supercritical carbon dioxide (S-CO2) cycles show potential advantages if compared to conventional plants. The current bottleneck in exploiting such cycles is the development of novel components such as turbomachines and heat-exchangers. This paper focuses on the layout arrangement and machinery design of a novel power block for a 10 to 15 MW supercritical carbon dioxide plant. The applied design procedure involves 0D and 1D models implemented using an in-house Fortran code, and 3D computational fluid dynamics (CFD) analyses using ANSYS-CFX. Novel configurations of the power block were designed, starting with the same primary thermal source. At nominal conditions, expected overall output powers from 13.2 to 16.2 MW were found. Finally, some qualitative considerations were included in the discussion to compare the analysed arrangements

Benefits of Yoga practice on body posture and on psychological and cognitive functions in children aged 8-10 years

Background. Many authors have reported benefits related to yoga practice. In particular, the scientific literature showed the influences of yoga on physical performance and cognitive functions. However, only few researches have examined the role of this training practice in children. For this reason, the purpose of the present study was to investigate the effects on body posture and features as self-esteem and attention in children aged 8-10 years. Materials and method. Sixty-five subjects (male n=28, female n=37) aged 8-10 years and attending primary school were enrolled for the study and randomly assigned into an experimental group (EG) which included 28 participants and a control group (CG) consisted of 37 participants. Both groups performed the curricular physical activity. Moreover, the EG performed a 5-months yoga intervention (from January to May 2018) for once/week with 60 minutes/session that provided breathing exercises (Pranayama) and posture-holding exercises (Ȃsana). Each participant was evaluated before (T0) and after (T1) the yoga protocol in order to assess any changes on body balance and postural control and on two peculiar aspects such as self-esteem and attention. Body posture, first with eyes open (EO) and then closed (EC), was measured through a stabilometric platform (freeMed® platform and freeStep® software produced by Sensor Medica®, Guidonia Montecelio, Roma, Italy), instead, using the Self-Esteem Multidimensional Assessment (TMA test) and an Executive Functions Test (ESA test) were evaluated the above-mentioned psychological aspect and cognitive function. Results. As concern stabilometric parameters, we found a significant difference (p<0.05) between T0 and T1 on Ellipse Sway Area (ESA) in the EG for both EO and EC conditions; moreover, our results showed a significant difference on the Sway Path Length (SPL) for the EG (p<0.0001) and for the CG (p<0.05). Furthermore, for the EG the ESA variable is correlated to the self-esteem in the EO condition as well as in the EC condition (p<0.0001). Conclusions. Our findings suggest that yoga practice may induce an increase of body stability and this is related to an improvement of self-esteem. These results support previous researches that have reported cognitive advantages and physical health benefits amongst yoga practitioners versus non-practitioners

Analytical and compositional aspects of isoflavones in food and their biological effects

This paper provides an overview of analytical techniques used to determine isoflavones (IFs) in foods and biological fluids with main emphasis on sample preparation methods. Factors influencing the content of IFs in food including processing and natural variability are summarized and an insight into IF databases is given. Comparisons of dietary intake of IFs in Asian and Western populations, in special subgroups like vegetarians, vegans, and infants are made and our knowledge on their absorption, distribution, metabolism, and excretion by the human body is presented. The influences of the gut microflora, age, gender, background diet, food matrix, and the chemical nature of the IFs on the metabolism of IFs are described. Potential mechanisms by which IFs may exert their actions are reviewed, and genetic polymorphism as determinants of biological response to soy IFs is discussed. The effects of IFs on a range of health outcomes including atherosclerosis, breast, intestinal, and prostate cancers, menopausal symptoms, bone health, and cognition are reviewed on the basis of the available in vitro, in vivo animal and human data