VIRTUAL TOURS FOR SMART CITIES: A COMPARATIVE PHOTOGRAMMETRIC APPROACH FOR LOCATING HOT-SPOTS IN SPHERICAL PANORAMAS

The paper aims to investigate the possibilities of using the panorama-based VR to survey data related to that set of activities for planning and management of urban areas, belonging to the Smart Cities strategies. The core of our workflow is to facilitate the visualization of the data produced by the infrastructures of the Smart Cities. A graphical interface based on spherical panoramas, instead of complex three-dimensional could help the user/citizen of the city to better know the operation related to control units spread in the urban area. From a methodological point of view three different kind of spherical panorama acquisition has been tested and compared in order to identify a semi-automatic procedure for locating homologous points on two or more spherical images starting from a point cloud obtained from the same images. The points thus identified allow to quickly identify the same hot-spot on multiple images simultaneously. The comparison shows how all three systems have proved to be useful for the purposes of the research but only one has proved to be reliable from a geometric point of view to identify the locators useful for the construction of the virtual tour

Assessment of seismic vulnerability of historical defensive walls

This paper presents a study on the behaviour of the walls of the Rocca Roveresca of Senigallia in Italy built in the XIV century on the ruins of a former Roman defensive struc-ture. This is a peculiar example of a small fortress that had undergone in the XV century im-portant modifications of the plant in order to enhance its defensive performances. A linear finite element model is first developed in order to understand the dynamic behaviour of a ge-neric portion of the wall and to detect the probable incipient failure mechanisms. A subse-quent static nonlinear analysis is carried out, with the same finite element model, to investigate the formation of the cracking layout and to detect the position of plastic hinges. The last analysis level is carried out with a tailored macro-element constituted by three bod-ies, namely the two external curtains and the inner fill for which a degradation of the behav-iour is considered. The results obtained demonstrates the efficiency of the wall against earthquakes characterized by return times typical for ultimate limit states. Same issues that deserve further investigation are highlighted

Converging Role for REEP1/SPG31 in Oxidative Stress

Mutations in the receptor expression-enhancing protein 1 gene (REEP1) are associated with hereditary spastic paraplegia type 31 (SPG31), a neurological disorder characterized by lengthdependent degeneration of upper motor neuron axons. Mitochondrial dysfunctions have been observed in patients harboring pathogenic variants in REEP1, suggesting a key role of bioenergetics in disease-related manifestations. Nevertheless, the regulation of mitochondrial function in SPG31 remains unclear. To elucidate the pathophysiology underlying REEP1 deficiency, we analyzed in vitro the impact of two different mutations on mitochondrial metabolism. Together with mitochondrial morphology abnormalities, loss-of-REEP1 expression highlighted a reduced ATP production with increased susceptibility to oxidative stress. Furthermore, to translate these findings from in vitro to preclinical models, we knocked down REEP1 in zebrafish. Zebrafish larvae showed a significant defect in motor axon outgrowth leading to motor impairment, mitochondrial dysfunction, and reactive oxygen species accumulation. Protective antioxidant agents such as resveratrol rescued free radical overproduction and ameliorated the SPG31 phenotype both in vitro and in vivo. Together, our findings offer new opportunities to counteract neurodegeneration in SPG31

A case of hemolytic anemia associated with interstitial lung disease, arthralgia and fever caused by <em>Mycoplasma pneumoniae</em>

Pulmonary interstitiopathies became the most diagnosed forms of pneumonia in 2020 due to the coronavirus (COVID-19) pandemic. The spectrum of interstitiopathies is broad and includes idiopathic diseases and secondary forms. In April 2020, a 36-year-old man was admitted to our department for arthralgias, fever, asthenia, cough, and dyspnea. In January 2020, fever, cough, arthralgias, and asthenia appeared. In April, his general condition worsened with the development of macrohematuria, malaise, and intense asthenia. On admission, the patient presented pale, asthenic, and symptomatic for dyspnea and arthralgias. There was objective joint pain in the small joints of the hands, elbow, and knees with morning stiffness and decreased strength. Computed tomography of the chest documented ground-glass opacities in both lung fields. He performed 2 swabs for severe acute respiratory syndrome-related coronavirus 2, which were negative. On hematochemical examination: immunoglobulin (IgM) 332 mg/dL and ferritin 700.2 ng/mL. At venous blood smear peripheral venous blood, agglutination of erythrocytes. The serology (IgM) for Mycoplasma pneumoniae was positive with agglutinins in the serum; doxaciclina was started. There was a progressive normalization of hemoglobin levels, cold agglutinins were gradually reduced and were no longer detected at 15 days after the start of treatment. At one month after discharge, pulmonary function had fully recovered, and the picture of hemolytic anemia was resolved

Risk assessment and prevention priorities in cultural heritage preservation

European Union has been promoting research actions on cultural heritage, recognizing and underlining its central role for the community policies and establishing its safeguard and valorisation as urgent priorities for the future. A research on rational tools for establishing seismic risk, intervention priorities, and decision-making on renovation of historical buildings and museums, just started at the University of Camerino, School of Architecture and Design, is described in this paper. The basic idea of the research is to develop a probabilistic methodology for the assessment of seismic risk of cultural Heritage starting from the Pacific Earthquake Engineering Research (PEER) approach, consisting of a general framework where the risk problem is decomposed into its three main features (i.e. seismic hazard, vulnerability and losses), analysed in a rigorous and consistent interdependent manner. The application of this methodology to cultural heritage requires investigations and original proposals on various open issues. This paper reports some results concerning the general methodology and preliminary analyses of a case study

Differential cross section measurements for the production of a W boson in association with jets in proton–proton collisions at √s = 7 TeV

Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript −1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good

Juxtaposing BTE and ATE – on the role of the European insurance industry in funding civil litigation

One of the ways in which legal services are financed, and indeed shaped, is through private insurance arrangement. Two contrasting types of legal expenses insurance contracts (LEI) seem to dominate in Europe: before the event (BTE) and after the event (ATE) legal expenses insurance. Notwithstanding institutional differences between different legal systems, BTE and ATE insurance arrangements may be instrumental if government policy is geared towards strengthening a market-oriented system of financing access to justice for individuals and business. At the same time, emphasizing the role of a private industry as a keeper of the gates to justice raises issues of accountability and transparency, not readily reconcilable with demands of competition. Moreover, multiple actors (clients, lawyers, courts, insurers) are involved, causing behavioural dynamics which are not easily predicted or influenced. Against this background, this paper looks into BTE and ATE arrangements by analysing the particularities of BTE and ATE arrangements currently available in some European jurisdictions and by painting a picture of their respective markets and legal contexts. This allows for some reflection on the performance of BTE and ATE providers as both financiers and keepers. Two issues emerge from the analysis that are worthy of some further reflection. Firstly, there is the problematic long-term sustainability of some ATE products. Secondly, the challenges faced by policymakers that would like to nudge consumers into voluntarily taking out BTE LEI

Search for stop and higgsino production using diphoton Higgs boson decays

Results are presented of a search for a "natural" supersymmetry scenario with gauge mediated symmetry breaking. It is assumed that only the supersymmetric partners of the top-quark (stop) and the Higgs boson (higgsino) are accessible. Events are examined in which there are two photons forming a Higgs boson candidate, and at least two b-quark jets. In 19.7 inverse femtobarns of proton-proton collision data at sqrt(s) = 8 TeV, recorded in the CMS experiment, no evidence of a signal is found and lower limits at the 95% confidence level are set, excluding the stop mass below 360 to 410 GeV, depending on the higgsino mass