Lista actualizada y revisión de la literatura de Harpellales (Kickxellomycotina) y otros endobiontes asociados al tracto digestivo de artrópodos de Argentina

The objective of this work is to further the knowledge of gut fungi, inhabiting the digestive tract of mandibulated arthropods, traditionally the Trichomycetes (currently Kicksellomycotina), in Argentina. The geographical distribution of these endobionts, especially in aquatic insects, but also other arthropods, is updated as well as host records and site information. Fungal species (Harpellales), which mostly colonize immature stages of aquatic insects, were identified in members of Coleoptera, Diptera, Ephemeroptera, Plecoptera, and Trichoptera from different biogeographical regions, from the far North in Jujuy province to the southernmost point in Tierra del Fuego. The overall goal of this review is to consolidate all the published and unpublished records from the country in order to summarize their geographical distribution.El objetivo de este trabajo es reunir toda la información publicada hasta el momento referida a este grupo de hongos, tradicionalmente conocidos como Trichomycetes (actualmente Kicksellomycotina), de la Argentina. El objetivo fue realizar un estado de avance sobre la distribución geográfica de estos endobiontes, especialmente viviendo en insectos acuáticos, pero también en otros artrópodos, con la actualización de registros de hospedadores e información de los sitios de recolección. Las especies de Harpellales colonizan estados inmaduros de insectos acuáticos y fueron identificados en miembros de Coleoptera, Diptera, Ephemeroptera, Plecoptera, y Trichoptera, de diferentes regiones biogeográficas desde el extremo Norte en la provincia de Jujuy al extremo más al Sur en Tierra del Fuego. El objetivo principal de este trabajo es consolidar todos los registros del material publicado y no publicado de la Argentina para resumir su distribución geográfica y lista de especies citadas.Facultad de Ciencias Naturales y MuseoCentro de Estudios Parasitológicos y de Vectore

Exploration of The Birth Planning and Complications Prevention Program Implementation

The Birth Planning and Complications Prevention Program or Program Perencanaan Persalinan dan Pencegahan Komplikasi (P4K) is an effort by the government to reduce the maternal mortality rate in Indonesia. This study aimed to determine the implementation of P4K to reduce maternal mortality in the catchment area of Waihaong Health Center Ambon in 2020. This was a qualitative study with a case study approach. Data collection was conducted in February-May 2020 in the catchment area of Waihaong Health Center. There were 13 informants interviewed in this study (nine pregnant women, two health workers, and two cadres). Data analysis was conducted using content analysis by identifying the emerging themes based on the research objectives. The results of this study show that the implementation of P4K has been running, but it has yet to be maximized because several P4K components still need to be completed. The pregnant woman prepares the components in the P4K sticker without any discussion with the midwife, and some pregnant women still choose to give birth with the help of a traditional birth attendant or “mama biang”. The mother's need for more knowledge about P4K and the lack of human resources as a program administrator was an obstacle to implementing this program. This study indicates that there is still a need for counseling for pregnant women to increase knowledge and awareness of the benefits of P4K and to carry out further training and collaboration between midwives and village cadres to improve P4K implementation

"What's (the) Matter?", A Show on Elementary Particle Physics with 28 Demonstration Experiments

We present the screenplay of a physics show on particle physics, by the Physikshow of Bonn University. The show is addressed at non-physicists aged 14+ and communicates basic concepts of elementary particle physics including the discovery of the Higgs boson in an entertaining fashion. It is also demonstrates a successful outreach activity heavily relying on the university physics students. This paper is addressed at anybody interested in particle physics and/or show physics. This paper is also addressed at fellow physicists working in outreach, maybe the experiments and our choice of simple explanations will be helpful. Furthermore, we are very interested in related activities elsewhere, in particular also demonstration experiments relevant to particle physics, as often little of this work is published. Our show involves 28 live demonstration experiments. These are presented in an extensive appendix, including photos and technical details. The show is set up as a quest, where 2 students from Bonn with the aid of a caretaker travel back in time to understand the fundamental nature of matter. They visit Rutherford and Geiger in Manchester around 1911, who recount their famous experiment on the nucleus and show how particle detectors work. They travel forward in time to meet Lawrence at Berkeley around 1950, teaching them about the how and why of accelerators. Next, they visit Wu at DESY, Hamburg, around 1980, who explains the strong force. They end up in the LHC tunnel at CERN, Geneva, Switzerland in 2012. Two experimentalists tell them about colliders and our heroes watch live as the Higgs boson is produced and decays. The show was presented in English at Oxford University and University College London, as well as Padua University and ICTP Trieste. It was 1st performed in German at the Deutsche Museum, Bonn (5/'14). The show has eleven speaking parts and involves in total 20 people.Comment: 113 pages, 88 figures. An up to date version of the paper with high resolution pictures can be found at http://www.th.physik.uni-bonn.de/People/dreiner/Downloads/. In v2 the acknowledgements and a citation are correcte

Lista actualizada y revisión de la literatura de Harpellales (Kickxellomycotina) y otros endobiontes asociados al tracto digestivo de artrópodos de Argentina

The objective of this work is to further the knowledge of gut fungi, inhabiting the digestive tract of mandibulated arthropods, traditionally the Trichomycetes (currently Kicksellomycotina), in Argentina. The geographical distribution of these endobionts, especially in aquatic insects, but also other arthropods, is updated as well as host records and site information. Fungal species (Harpellales), which mostly colonize immature stages of aquatic insects, were identified in members of Coleoptera, Diptera, Ephemeroptera, Plecoptera, and Trichoptera from different biogeographical regions, from the far North in Jujuy province to the southernmost point in Tierra del Fuego. The overall goal of this review is to consolidate all the published and unpublished records from the country in order to summarize their geographical distribution.El objetivo de este trabajo es reunir toda la información publicada hasta el momento referida a este grupo de hongos, tradicionalmente conocidos como Trichomycetes (actualmente Kicksellomycotina), de la Argentina. El objetivo fue realizar un estado de avance sobre la distribución geográfica de estos endobiontes, especialmente viviendo en insectos acuáticos, pero también en otros artrópodos, con la actualización de registros de hospedadores e información de los sitios de recolección. Las especies de Harpellales colonizan estados inmaduros de insectos acuáticos y fueron identificados en miembros de Coleoptera, Diptera, Ephemeroptera, Plecoptera, y Trichoptera, de diferentes regiones biogeográficas desde el extremo Norte en la provincia de Jujuy al extremo más al Sur en Tierra del Fuego. El objetivo principal de este trabajo es consolidar todos los registros del material publicado y no publicado de la Argentina para resumir su distribución geográfica y lista de especies citadas.Facultad de Ciencias Naturales y MuseoCentro de Estudios Parasitológicos y de Vectore

Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming

The limited therapeutic options available for hepatocellular carcinoma (HCC) make mandatory to find alternative effective treatments for this tumor. Based on the recent finding that systemic or local hypothyroidism is associated with HCC development in humans and rodents, we investigated whether the thyroid hormone triiodothyronine (T3) could inhibit the progression of hepatocellular carcinomas (HCCs)

The protective role of Lactobacillus rhamnosus GG postbiotic on the alteration of autophagy and inflammation pathways induced by gliadin in intestinal models

Celiac disease (CD) is an autoimmune enteropathy caused by an abnormal immune response to gliadin peptides in genetically predisposed individuals. For people with CD, the only available therapy thus far is the lifelong necessity for a gluten-free diet (GFD). Innovative therapies include probiotics and postbiotics as dietary supplements, both of which may benefit the host. Therefore, the present study aimed to investigate the possible beneficial effects of the postbiotic Lactobacillus rhamnosus GG (LGG) in preventing the effects induced by indigested gliadin peptides on the intestinal epithelium. In this study, these effects on the mTOR pathway, autophagic function, and inflammation have been evaluated. Furthermore, in this study, we stimulated the Caco-2 cells with the undigested gliadin peptide (P31-43) and with the crude gliadin peptic-tryptic peptides (PTG) and pretreated the samples with LGG postbiotics (ATCC 53103) (1 × 108). In this study, the effects induced by gliadin before and after pretreatment have also been investigated. The phosphorylation levels of mTOR, p70S6K, and p4EBP-1 were increased after treatment with PTG and P31-43, indicating that the intestinal epithelial cells responded to the gliadin peptides by activating the mTOR pathway. Moreover, in this study, an increase in the phosphorylation of NF-κβ was observed. Pretreatment with LGG postbiotic prevented both the activation of the mTOR pathway and the NF-κβ phosphorylation. In addition, P31-43 reduced LC3II staining, and the postbiotic treatment was able to prevent this reduction. Subsequently, to evaluate the inflammation in a more complex intestinal model, the intestinal organoids derived from celiac disease patient biopsies (GCD-CD) and controls (CTR) were cultured. Stimulation with peptide 31-43 in the CD intestinal organoids induced NF-κβ activation, and pretreatment with LGG postbiotic could prevent it. These data showed that the LGG postbiotic can prevent the P31-43-mediated increase in inflammation in both Caco-2 cells and in intestinal organoids derived from CD patients

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Search for heavy resonances decaying to two Higgs bosons in final states containing four b quarks

A search is presented for narrow heavy resonances X decaying into pairs of Higgs bosons (H) in proton-proton collisions collected by the CMS experiment at the LHC at root s = 8 TeV. The data correspond to an integrated luminosity of 19.7 fb(-1). The search considers HH resonances with masses between 1 and 3 TeV, having final states of two b quark pairs. Each Higgs boson is produced with large momentum, and the hadronization products of the pair of b quarks can usually be reconstructed as single large jets. The background from multijet and t (t) over bar events is significantly reduced by applying requirements related to the flavor of the jet, its mass, and its substructure. The signal would be identified as a peak on top of the dijet invariant mass spectrum of the remaining background events. No evidence is observed for such a signal. Upper limits obtained at 95 confidence level for the product of the production cross section and branching fraction sigma(gg -> X) B(X -> HH -> b (b) over barb (b) over bar) range from 10 to 1.5 fb for the mass of X from 1.15 to 2.0 TeV, significantly extending previous searches. For a warped extra dimension theory with amass scale Lambda(R) = 1 TeV, the data exclude radion scalar masses between 1.15 and 1.55 TeV

Measurement of t(t)over-bar normalised multi-differential cross sections in pp collisions at root s=13 TeV, and simultaneous determination of the strong coupling strength, top quark pole mass, and parton distribution functions

Peer reviewe