Los accidentes de tráfico desde el punto de vista de los medios impresos. Guadalajara, México 2011 = The Road-Traffic Accidents from the Point of View of the Print Mass Media. Guadalajara, Mexico 2011

Resumen: Introducción. Los medios de comunicación tienen un papel importante en la Salud Pública al informar a la población. Uno de los temas que más ha cobrado interés en nuestro país son los accidentes de tráfico, por lo que nos interesa analizar el papel de los medios en este problema de salud. Objetivo. Analizar el contenido de las notas periodísticas relacionadas con siniestros viales, publicados en abril y mayo de 2011. Material y métodos. Es un estudio de análisis de contenido acumulativo que recabó notas periodísticas de tres diarios con distribución en Guadadalajara, México; las cuales fueron clasificadas de acuerdo al tipo de nota y posteriormente, para la codificación solamente se consideraron las piezas informativas, con los que se conformaron categorías. Resultados. Durante el período se captaron 196 notas periodísticas, de éstas 112 fueron reportes de evento, 78 piezas informativas, principalmente. De la codificación resultaron tres categorías principales: actores involucrados, causalidad y medidas para la disminución de accidentes. Conclusión. Los medios impresos no están siendo aprovechados para ofrecer información a la población sobre medidas preventivas y factores de riesgo, la mayor parte de la notas no exponen las causas de los accidentes de tráfico describen el evento y fincan responsabilidades. Palabras clave: accidentes de tránsito, prevención de accidentes, artículo de periódico, análisis cualitativo Abstract: Background. The media have an important role on Public Health to provide information to the population. In the country, traffic accidents are an important topic, that is the reason for analyze the print media role in the traffic accidents. Objective. Analyze the Content of News from Print Media about Road-Traffic Accidents, published between April and May, 2011. Material and Methods. It´s a Summative Content Analysis that included News Reports of three Newspapers with distribution in Guadalajara, Mexico. Those news reports were classified by the content and then, for the codification only included informative notes, which ones formed category. Results. During the period, we captured 196 news reports, of these 112 were reports on crash, 78 informational pieces, principally. From codification resulted three mainly category: stakeholders, causality and actions for reducing accidents. Conclusions. The Print Mass Media are being underestimate to provide information about prevention and risks factors, because most of news reports did not expose causes of the Road-Traffic accidents but described the road-traffic accident and they looked for responsibilities. Keywords: traffic accident, accident prevention, newspaper article, qualitative analysi

Neutron radiobiology studies with a pure cold neutron beam

Data on the radiobiological effects of thermal neutrons are usually obtained from irradiations in a mixed field of neutrons of different energies and gamma rays or from conversion of proton data with similar energies to those created in the neutron capture on nitrogen. Experimental data from irradiations in a pure thermal or cold neutron beam can help to find new values for neutron relative biological effectiveness (RBE) factors, which are useful for BNCT (Boron Neutron Capture Therapy) and radiation protection applications. We present a new experimental setup for radiobiological studies at a cold neutron beam at Institut Laue-Langevin, a beam without fast neutron component and almost no gamma ray contribution. After the irradiation, survival assays are performed to obtain the survival curves. Finally, comparing with a reference photon irradiation, the thermal neutron RBE factors can be calculated. The methodology is outlined at the example of A375 melanoma cells for which new radiobiological data were obtained.We acknowledge financial support for this work from the Fundación Científica de la Asociación Española Contra el Cáncer (AECC) under grant PS16163811PORR, Junta de Andalucía (Andalusian Regional Government), under contract P11-FQM-8229, Spanish MINECO and FEDER funds under contract FIS2015-69941-C2-1-P, the grant agreement ILL-UGR and the founders of the University of Granada Chair Neutrons for Medicine: Spanish Fundación ACS and Capitán Antonio. M.P. acknowledges a grant under the program Becas de Iniciación a la Investigación from the Universidad de Granada (Plan Propio de Investigación). The open access fee was covered by FILL2030, a European Union project within the European Commission’s Horizon 2020 Research and Innovation programme under grant agreement N°731096

SEEDS STORED IN THE FOREST FLOOR IN A NATURAL STAND OF Pinus montezumae Lamb

ABSTRACT Seed banks have been studied to a greater extent in agriculture than in forestry due to long-standing concerns about the threat to agricultural crops posed by weed species. However, in forest areas seed banks have an important influence on plant succession since the vegetation that colonizes a space after a major disturbance will arise at least partly from them. Knowledge about this condition can help land managers to prescribe site treatments that produce desired vegetation from the perspectives of wildlife habitat, reduced plant competition with crop tree species, and related management concerns. The variability of the soil seed bank of a Pinus montezumae forest was assessed using seedling-emergence method for soil samples. The number of species and seedling abundance were evaluated by sampling four plots in a natural regeneration area. A total of 43 species were recorded in the seed bank (2 trees, 17 shrubs, 1 grass and 23 herbs). Viable seeds of most species were contained in similar abundance in the humus and mineral soil layers. Dominant species in the stand (P. montezumae) and codominant species (P. ayacahuite, Abies religiosa, and Alnus firmifolia) were poorly represented in the soil seed bank which was dominated by seeds of an array of annual and perennial herbs. Regeneration of commercial species under any silvicultural method must come from current seed production, or seed produced off site, but not from the soil seed bank. RESUMEN Los bancos de semillas han sido estudiados más en la agricultura que en el área forestal debido a la preocupación sobre el peligro de que los cultivos sean dominados por malas hierbas. Tienen una gran influencia en la sucesión vegetal que coloniza un área después de un disturbio. El conocimiento sobre bancos de semillas en el suelo puede ayudar a prescribir los tratamientos que propicien condiciones de vegetación deseadas desde la perspectiva de hábitat de fauna silvestre, reducción de competencia con especies de importancia y otros problemas relacionados con el manejo forestal. La variación del banco de semillas en el suelo de un bosque de Pinus montezumae fue evaluado por medio del método de emergencia en muestras de suelo; se determinó la abundancia y el número de taxa mediante el muestreo en cuatro parcelas en un área de regeneración natural. Los resultados indican 43 especies (dos de árboles, 17 de arbustos, una de pasto y 23 de hierbas). La abundancia de semillas viables fue similar para la mayoría de ellas en la capa de humus y suelo mineral; en tanto que las dominantes del rodal (P. montezumae) y codominantes (P. ayacahuite, Abies religiosa y Alnus firmifolia), no estuvieron presentes en el banco, en el cual dominaron herbáceas anuales y perennes. La regeneración de las especies comerciales para este tipo de bosque, bajo cualquier método silvícola, debe provenir de semilla producida en el año in situ o de áreas aledañas, pero no del banco de semillas. Palabras clave: Abies religiosa, Alnus firmifolia, regeneración natural, Pinus montezumae Lamb., plántula, banco de semillas en el suelo

CDH1 somatic alterations in Mexican patients with diffuse and mixed sporadic gastric cancer

Background: Diffuse gastric cancer (DGC) is associated with the reduction or absence of the expression of the cell adhesion protein E-cadherin (encoded by the CDH1 gene). Molecular characteristics are less well described for mixed gastric cancer (MGC). The main somatic alterations that have been described in the CDH1 gene are mutations, loss of heterozygosity (LOH) and promoter methylation. The aim was to analyze CDH1 somatic alterations in Mexican patients with diffuse and mixed gastric cancer. Methods: We searched for mutations in the CDH1 gene in tumor DNA from DGC (n = 13) and MGC (n = 7) patients by next generation sequencing (NGS). Validation of findings was performed using Sanger sequencing. LOH was analyzed using dinucleotide repeat markers surrounding the CDH1 gene, and methylation was investigated by DNA bisulfite conversion and sequencing. E-cadherin protein deficiency was analyzed by immunohistochemistry. Results: Seventeen point variants were identified by NGS, 13 of them were validated by Sanger sequencing. Only 1/13 had not been previously reported (c.-137C > A), and 12/13 were already reported as polymorphisms. Two DGC cases presented LOH at the locus 16q22.1 (13.3%). CDH1 promoter methylation was positive in (7/11) 63.6% and (4/6) 66.6% of the cases with DGC and MGC, respectively. E-cadherin protein deficiency was observed in 58.3% of DGC cases while 100% in MGC cases. Conclusions: While no pathogenic somatic mutations were found that could explain the diffuse histology of gastric cancer in DGC and MGC, methylation was the most common somatic inactivation event of the CDH1 gene, and LOH was rare. The previously unreported c.-137C > A variant modify the CDH1 gene expression since it alters the binding sites for transcription factors.This work was supported by the “Consejo Nacional de Ciencia y Tecnología (CONACYT)” (grant Ciencia Básica 2013–1-222972) and by the “Fondo de Investigación en Salud (FIS), Instituto Mexicano del Seguro Social (IMSS)” (grant FIS/IMSS/PROT/G13/1189), that contributed to the design of the study, collection, analysis, interpretation of data and writing the manuscript. We thank the following institutions: 1) Coordinación de Investigación en Salud (CIS), Instituto Mexicano del Seguro Social (IMSS) for the support given to ARBC, through the Professional Development in the International Research of Graduate Students (PRODESI) program; 2) Fundación IMSS, A.C. for the research grant awarded to JYSL and MTMT; 3) FEDER - Fundo Europeu de Desenvolvimento Regional funds through the COMPETE 2020 - Operational Programme for Competitiveness and Internationalisation (POCI), Portugal 2020, and by Portuguese funds through FCT/ Ministério da Ciência, Tecnologia e Inovação in the framework of the project “Institute for Research and Innovation in Health Sciences” (POCI-01-0145-FEDER-007274); 4) The project NORTE-01-0145-FEDER-000029, supported by Norte Portugal Regional Programme (NORTE 2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF); 5) FCT fellowships (SFRH/BPD/86543/2012 to JC; SFRH/BPD/89764/2012 to PO; PD/ BD/128007/2016 to AS). IPATIMUP integrates the i3S Research Unit, which is partially supported by FCT, the Portuguese Foundation for Science and Technology

Comparison of two phenotypical methods to segregate resistant and susceptible lambs to parasitic nematodes

The objective of this study was to compare two segregation methods to select resistant and susceptible female Pelibuey lambs infected naturally with gastrointestinal nematodes (GINs) in relation to their haematological and immunological response. For 6 months, faeces and blood samples were taken fortnightly from 40 grazing 5-month-old female lambs. The lambs were classified according to two methods using faecal egg count (FEC) as a phenotypical trait. In the first (reference) method (M3SE, n = 22), resistant (RES) lambs had FEC lower than the mean – 3 standard errors, the susceptible (SUS) lambs levels higher than + 3 standard errors(n = 10) and the intermediate (INT) lambs (n = 8) were categorised by having FECs between the two values. The second method (QUM) divided the population, using quartiles, into resistant (RES; 25%), intermediate (INT; 50%), and susceptible (SUS; 25%) lambs. The agreement between both methods was estimated using the Kappa index. The packed cell volume (PCV), total plasma protein (TPP) and peripheral eosinophils (EOS) were determined for each group. Serum was used to evaluate the IgA levels. PCV and TPP values were higher (P<0.01) in the RES lambs (31.5 ± 3.4 and 6.16 ± 0.5 g/dL by QUM, respectively, and 31.5 ± 3.9 and 6.24 ± 0.49 g/dL by M3SE, respectively) than the SUS lambs (28.1 ± 4.7 and 5.94 ± 0.5 g/d, respectively, by both methods). The EOS and IgA values increased with age. M3SE and QUM were in moderate agreement (Kappa = 0.43). We concluded that the two segregation methods allowed for the identification of the same female SUS lambs, but a greater number of animals were categorised phenotypically as resistant using the M3SE method. PCV and TPP can help to identify phenotypically resistant animals

The Fourteenth Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the extended Baryon Oscillation Spectroscopic Survey and from the second phase of the Apache Point Observatory Galactic Evolution Experiment

The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) has been in operation since July 2014. This paper describes the second data release from this phase, and the fourteenth from SDSS overall (making this, Data Release Fourteen or DR14). This release makes public data taken by SDSS-IV in its first two years of operation (July 2014-2016). Like all previous SDSS releases, DR14 is cumulative, including the most recent reductions and calibrations of all data taken by SDSS since the first phase began operations in 2000. New in DR14 is the first public release of data from the extended Baryon Oscillation Spectroscopic Survey (eBOSS); the first data from the second phase of the Apache Point Observatory (APO) Galactic Evolution Experiment (APOGEE-2), including stellar parameter estimates from an innovative data driven machine learning algorithm known as "The Cannon"; and almost twice as many data cubes from the Mapping Nearby Galaxies at APO (MaNGA) survey as were in the previous release (N = 2812 in total). This paper describes the location and format of the publicly available data from SDSS-IV surveys. We provide references to the important technical papers describing how these data have been taken (both targeting and observation details) and processed for scientific use. The SDSS website (www.sdss.org) has been updated for this release, and provides links to data downloads, as well as tutorials and examples of data use. SDSS-IV is planning to continue to collect astronomical data until 2020, and will be followed by SDSS-V.Comment: SDSS-IV collaboration alphabetical author data release paper. DR14 happened on 31st July 2017. 19 pages, 5 figures. Accepted by ApJS on 28th Nov 2017 (this is the "post-print" and "post-proofs" version; minor corrections only from v1, and most of errors found in proofs corrected

The High-Altitude Water Cherenkov (HAWC) Observatory in M\'exico: The Primary Detector

The High-Altitude Water Cherenkov (HAWC) observatory is a second-generation continuously operated, wide field-of-view, TeV gamma-ray observatory. The HAWC observatory and its analysis techniques build on experience of the Milagro experiment in using ground-based water Cherenkov detectors for gamma-ray astronomy. HAWC is located on the Sierra Negra volcano in M\'exico at an elevation of 4100 meters above sea level. The completed HAWC observatory principal detector (HAWC) consists of 300 closely spaced water Cherenkov detectors, each equipped with four photomultiplier tubes to provide timing and charge information to reconstruct the extensive air shower energy and arrival direction. The HAWC observatory has been optimized to observe transient and steady emission from sources of gamma rays within an energy range from several hundred GeV to several hundred TeV. However, most of the air showers detected are initiated by cosmic rays, allowing studies of cosmic rays also to be performed. This paper describes the characteristics of the HAWC main array and its hardware.Comment: Accepted for publications in Nuclear Inst. and Methods in Physics Research, A (2023) 168253 ( https://www.sciencedirect.com/science/article/abs/pii/S0168900223002437 ); 39 pages, 14 Figure

The clustering of the SDSS-IV extended Baryon Oscillation Spectroscopic Survey DR14 quasar sample: first measurement of baryon acoustic oscillations between redshift 0.8 and 2.2

We present measurements of the Baryon Acoustic Oscillation (BAO) scale in redshift-space using the clustering of quasars. We consider a sample of 147,000 quasars from the extended Baryon Oscillation Spectroscopic Survey (eBOSS) distributed over 2044 square degrees with redshifts $0.8 < z < 2.2$ and measure their spherically-averaged clustering in both configuration and Fourier space. Our observational dataset and the 1400 simulated realizations of the dataset allow us to detect a preference for BAO that is greater than 2.8$\sigma$. We determine the spherically averaged BAO distance to $z = 1.52$ to 3.8 per cent precision: $D_V(z=1.52)=3843\pm147 \left(r_{\rm d}/r_{\rm d, fid}\right)\$Mpc. This is the first time the location of the BAO feature has been measured between redshifts 1 and 2. Our result is fully consistent with the prediction obtained by extrapolating the Planck flat $\Lambda$CDM best-fit cosmology. All of our results are consistent with basic large-scale structure (LSS) theory, confirming quasars to be a reliable tracer of LSS, and provide a starting point for numerous cosmological tests to be performed with eBOSS quasar samples. We combine our result with previous, independent, BAO distance measurements to construct an updated BAO distance-ladder. Using these BAO data alone and marginalizing over the length of the standard ruler, we find $\Omega_{\Lambda} > 0$ at 6.6$\sigma$ significance when testing a $\Lambda$CDM model with free curvature.Comment: Accepted by MNRAS; BAO distance likelihood available in source files 'QSOv1.9fEZmock_BAOchi2.dat'; full set of data to be public eventually from SDSS websit

Marco activo de recursos de innovación docente: Madrid

Una guía de espacios e instituciones para actividades educativas complementarias en enseñanza secundaria y Formación Profesional

Effects of Data Quality Vetoes on a Search for Compact Binary Coalescences in Advanced LIGO's First Observing Run

The first observing run of Advanced LIGO spanned 4 months, from September 12, 2015 to January 19, 2016, during which gravitational waves were directly detected from two binary black hole systems, namely GW150914 and GW151226. Confident detection of gravitational waves requires an understanding of instrumental transients and artifacts that can reduce the sensitivity of a search. Studies of the quality of the detector data yield insights into the cause of instrumental artifacts and data quality vetoes specific to a search are produced to mitigate the effects of problematic data. In this paper, the systematic removal of noisy data from analysis time is shown to improve the sensitivity of searches for compact binary coalescences. The output of the PyCBC pipeline, which is a python-based code package used to search for gravitational wave signals from compact binary coalescences, is used as a metric for improvement. GW150914 was a loud enough signal that removing noisy data did not improve its significance. However, the removal of data with excess noise decreased the false alarm rate of GW151226 by more than two orders of magnitude, from 1 in 770 years to less than 1 in 186000 years.Comment: 27 pages, 13 figures, published versio