Estudo inicial sobre a evolução do novo CORONAVÍRUS (SARS-COV-2) no estado do Pará (Brasil), no período entre 17/03/2020 e 06/04/2020.

O presente artigo apresenta o estudo inicial sobre a evolução do novo coronavírus (SARS-CoV-2) no estado do Pará, desde a confirmação do primeiro infectado no dia 18/03/2020 até o dia 06/04/2020.O estudo apresenta também um modelo matemático para estimar o número de infectados até o dia 06/05/2020. Os resultados mostram que o modelo é confiável para predições de curto prazo, cuja evolução pode ser de 1 infectado em 18/03/2020 a 761 infectados em 18/04/2020.This paper presents the initial study on the evolution of Coronavirus (SARS-CoV-2) in the state of Pará, from the confirmation of the first infected on 18/03/2020 until 06/04/2020. The study also presents a mathematical model for estimating the number of infected by 06/05/2020. The results show that the model is reliable for short-term predictions, whose evolution can be from 01 infected on 03/18/2020 to 761 infected on 18/04/2020

Estudo Nº2 sobre a evolução do novo Coronavírus (SARS-CoV-2) no estado do Pará (Brasil), Março – Junho, 2020/ Study Nº2 on the evolution of new Coronavirus (SARS-CoV-2) in the state of Pará (Brazil), March – June 2020

O presente artigo apresenta o segundo estudo sobre a evolução do novo coronavírus (SARS-CoV-2) no estado do Pará, desde a confirmação do primeiro infectado no dia 18/03/2020 até o dia 28/05/2020, através de mapas. O estudo apresenta também um modelo matemático para estimar o número de infectados até o dia 28/05/2020 e a projeção de pico da epidemia no estado do Pará como um todo, com análises mais detalhadas em dez municípios incluindo a capital Belém. Os resultados mostram que o modelo possui confiabilidade acima de 90% para predições de curto prazo, cuja evolução pode ser de 1 infectado em 18/03/2020 a 33.304 infectados em 28/05/2020

Allergic Rhinitis and its Impact on Asthma (ARIA) Phase 4 (2018) : Change management in allergic rhinitis and asthma multimorbidity using mobile technology

Allergic Rhinitis and its Impact on Asthma (ARIA) has evolved from a guideline by using the best approach to integrated care pathways using mobile technology in patients with allergic rhinitis (AR) and asthma multimorbidity. The proposed next phase of ARIA is change management, with the aim of providing an active and healthy life to patients with rhinitis and to those with asthma multimorbidity across the lifecycle irrespective of their sex or socioeconomic status to reduce health and social inequities incurred by the disease. ARIA has followed the 8-step model of Kotter to assess and implement the effect of rhinitis on asthma multimorbidity and to propose multimorbid guidelines. A second change management strategy is proposed by ARIA Phase 4 to increase self-medication and shared decision making in rhinitis and asthma multimorbidity. An innovation of ARIA has been the development and validation of information technology evidence-based tools (Mobile Airways Sentinel Network [MASK]) that can inform patient decisions on the basis of a self-care plan proposed by the health care professional.Peer reviewe

Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study

Background: Mobile technology may help to better understand the adherence to treatment. MASK-rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient-centred ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries. Objectives: To assess the adherence to treatment in allergic rhinitis patients using the Allergy Diary App. Methods: An observational cross-sectional study was carried out on all users who filled in the Allergy Diary from 1 January 2016 to 1 August 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach. Results: A total of 12143 users were registered. A total of 6949 users reported at least one VAS data recording. Among them, 1887 users reported >= 7 VAS data. About 1195 subjects were included in the analysis of adherence. One hundred and thirty-six (11.28%) users were adherent (MPR >= 70% and PDC = 70% and PDC = 1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non-adherent to medications (MPR Conclusion and clinical relevance: Adherence to treatment is low. The relative efficacy of continuous vs on-demand treatment for allergic rhinitis symptoms is still a matter of debate. This study shows an approach for measuring retrospective adherence based on a mobile app. This also represents a novel approach for analysing medication-taking behaviour in a real-world setting.Peer reviewe

DEVELOPMENT OF ACTIVATED CARBON FROM BAMBOO (Bambusa vulgaris) FOR PESTICIDE REMOVAL FROM AQUEOUS SOLUTIONS

Considering the water scarcity problems facing many countries, the need for water reuse can make activated carbon (AC) an essential product for modern society. In this context, to contribute with better activated carbons that could be used to serve in water treatment, this article discusses these materials production, using bamboo as raw material, and analyses their application effectiveness. The bamboo was collected, transformed into activated carbon, by simultaneous chemical and physical activations, and named H3PO4/H2OAC. The obtained material was characterized by its yield, apparent density, ash content, thermogravimetric analysis, surface area, methylene blue and iodine indexes, pH and point of zero charge analysis, scanning electron microscopy and Boehm titration method. The AC was used as adsorbent for removing the metribuzin, 2,4-dichlorophenoxyacetic acid and furadan pesticides. The H3PO4/H2OAC had a surface area of 1196.30 m².g-1 and the obtained adsorption capacity was elevated for furadan (868.98 mg.g-1), metribuzin (756.47 mg.g-1) and 2,4-dichlorophenoxyacetic acid (274.70 mg.g-1)

Activity of Sodium Trimetaphosphate Nanoparticles on Cariogenic-Related Biofilms In Vitro

In light of the promising effect of sodium trimetaphosphate nanoparticles (TMPn) on dental enamel, in addition to the scarce evidence of the effects of these nanoparticles on biofilms, this study evaluated the activity of TMPn with/without fluoride (F) on the pH, inorganic composition and extracellular matrix (ECM) components of dual-species biofilms of Streptococcus mutans and Candida albicans. The biofilms were cultivated in artificial saliva in microtiter plates and treated with solutions containing 1% or 3% conventional/microparticulate TMP (TMPm) or TMPn, with or without F. After the last treatment, the protein and carbohydrate content of the ECM was analyzed, and the pH and F, calcium (Ca), phosphorus (P), and TMP concentrations of the biofilms were determined. In another set of experiments, after the last treatment, the biofilms were exposed to a 20% sucrose solution, and their matrix composition, pH, and inorganic component contents were evaluated. 3% TMPn/F significantly reduced ECM carbohydrate and increased biofilm pH (after sucrose exposure) than other treatments. Also, it significantly increased P and F levels before sucrose exposure in comparison to 3% TMPm/F. In conclusion, 3% TMPn/F affected the biofilm ECM and pH, besides influencing inorganic biofilm composition by increasing P and F levels in the biofilm fluid

Estudo inicial sobre a evolução do novo CORONAVÍRUS (SARS-COV-2) no estado do Pará (Brasil), no período entre 17/03/2020 e 06/04/2020 / Initial study on the evolution of the new CORONAVIRUS (SARS-COV-2) in the state of Pará (Brazil), in the period between 03/17/2020 and 06/04/2020

O presente artigo apresenta o estudo inicial sobre a evolução do novo coronavírus (SARS-CoV-2) no estado do Pará,desde a confirmação do primeiro infectado no dia 18/03/2020 até o dia 06/04/2020.O estudo apresenta também um modelo matemático para estimar o número de infectados até o dia 06/05/2020. Os resultados mostram que o modelo é confiável para predições de curto prazo, cuja evolução pode ser de 1 infectado em 18/03/2020 a 761 infectados em 18/04/2020.