Estimation of the genetic diversity of jabuticaba trees and association among fruit characters

The aim of this study was to evaluate the genetic dissimilarity of different jabuticaba tree accessions from Prudente de Moraes, Minas Gerais State, Brazil, based on fruit characters. The genetic diversity study was carried out based on characters evaluated in fruits, and with the elimination of redundant descriptors, nine characters were selected to estimate genetic divergence and perform clustering. The Standardized Mean Euclidian Distance was used as dissimilarity measure. The clustering methods used were Tocher and the nearest neighbor. Correlation analysis among characters was performed by Pearson correlation (p> 0.05). Accessions 4, 5, 7 and 12 have potential for in improvement programs aiming for productivity. The character that contributed most to the genetic diversity of the accessions were the soluble solids important for the processing industry and for fresh consumption. Genotypes showed variability for most characters analyzed showing the possibility of selection and identification of parents that will be used in future crossings.The aim of this study was to evaluate the genetic dissimilarity of different jabuticaba tree accessions from Prudente de Moraes, Minas Gerais State, Brazil, based on fruit characters. The genetic diversity study was carried out based on characters evaluated in fruits, and with the elimination of redundant descriptors, nine characters were selected to estimate genetic divergence and perform clustering. The Standardized Mean Euclidian Distance was used as dissimilarity measure. The clustering methods used were Tocher and the nearest neighbor. Correlation analysis among characters was performed by Pearson correlation (p> 0.05). Accessions 4, 5, 7 and 12 have potential for in improvement programs aiming for productivity. The character that contributed most to the genetic diversity of the accessions were the soluble solids important for the processing industry and for fresh consumption. Genotypes showed variability for most characters analyzed showing the possibility of selection and identification of parents that will be used in future crossings

Eucalyptus shading and allelopathy in the germination and development of pitaya (Hylocereusundatus)

Eucalyptus spp. it is known to be part of most forests planted for commercial use in Brazil, however when intercropped with Pitaia (Hylocereus undatus), few studies report this interaction. The objective of this work was to evaluate the effects of shading and the existence of allelopathic interaction between Eucalyptus spp and pitaia (H. undatus) in the field, as well as the action of eucalyptus leaf extract in the germination of pitaia seeds in laboratory conditions. In the field experiment, the statistical model of randomized block design (DBC) was used, with the use of adult plants of pitaia and eucalyptus, evaluating the following variables: number of shoots in the aerial part; number of flowers; crown diameter; circumference of the cladode; number of fruits and the variation in the amount of light reaching the plants. It was observed that the plants that were outside the eucalyptus forest showed better results. In the second experiment, the allelopathic action of different concentrations of aqueous extracts of eucalyptus leaves on the germination of pitaia seeds was evaluated. This experiment was carried out in DIC with four repetitions of 60 pitaia seeds. These seeds were then subjected to treatments with different dilutions, varying from 0% (control), 12.5%, 25% and 50% of the stock solution. It was observed that as the leaf extract concentrations increased, germination decreased. The concentrations of 0% (control) and 12.5% ​​showed better results. In conclusion, in fact, eucalyptus exerted an allelopathic action on pitaia plants.Eucalyptus spp. it is known to be part of most forests planted for commercial use in Brazil, however when intercropped with Pitaia (Hylocereus undatus), few studies report this interaction. The objective of this work was to evaluate the effects of shading and the existence of allelopathic interaction between Eucalyptus spp and pitaia (H. undatus) in the field, as well as the action of eucalyptus leaf extract in the germination of pitaia seeds in laboratory conditions. In the field experiment, the statistical model of randomized block design (DBC) was used, with the use of adult plants of pitaia and eucalyptus, evaluating the following variables: number of shoots in the aerial part; number of flowers; crown diameter; circumference of the cladode; number of fruits and the variation in the amount of light reaching the plants. It was observed that the plants that were outside the eucalyptus forest showed better results. In the second experiment, the allelopathic action of different concentrations of aqueous extracts of eucalyptus leaves on the germination of pitaia seeds was evaluated. This experiment was carried out in DIC with four repetitions of 60 pitaia seeds. These seeds were then subjected to treatments with different dilutions, varying from 0% (control), 12.5%, 25% and 50% of the stock solution. It was observed that as the leaf extract concentrations increased, germination decreased. The concentrations of 0% (control) and 12.5% ​​showed better results. In conclusion, in fact, eucalyptus exerted an allelopathic action on pitaia plants

Crescimento e marcha de absorção de macronutrientes em genótipos de jabuticabeira ‘Sabará’ cultivados em solução nutritiva

The knowledge about growth and nutrient accumulation can help improve fertilizer efficiency in the production of jabuticaba seedlings, which is still carried out in an empirical way. This study aimed at determining the growth and macronutrient uptake in ‘Sabará’ jabuticaba genotypes grown in nutrient solution. The experiment was carried out in a completely randomized design in split plots, with four replications. In the main plots three jabuticaba genotypes (J001, J005 and J012) were cultivated in nutrient solution and six evaluation periods (at 60, 120, 180, 240, 300 and 360 days) in the sub-plots were evaluated. Plant height, root length, stem diameter, leaf area index and dry matter (root, stem and leaves) in each period were evaluated. The accumulation of macronutrients in different plant organs was determined, as well as the accumulation of nutrients as a function of time adjusted to the linear model. The results showed that the cultivation in nutrient solution was efficient in the production of Sabará jabuticabeira seedlings. There was no difference in macronutrient growth and absorption among jabuticaba genotypes grown in nutrient solution. ‘Sabará’ jabuticaba plants accumulated (in mg plant-1) 559 of N, 45 of P, 443 of K, 363 of Ca, 59 of Mg and 82 of S. The distribution of macronutrient accumulations in jabuticaba showed the following order: leaves > stem > roots.O conhecimento sobre o crescimento e o acúmulo de nutrientes poderá contribuir para a melhoria da eficiência da adubação na produção de mudas de jabuticabeira, que ainda é realizada de forma empírica. Neste estudo, objetivou-se determinar o crescimento e a marcha de absorção de macronutrientes em genótipos de jabuticabeira Sabará cultivados em solução nutritiva. O experimento conduzido em delineamento inteiramente casualizado em parcelas subdivididas, com quatro repetições. Nas parcelas principais, foram utilizados três genótipos de jabuticabeira (J001, J002 e J003) e, nas subparcelas, foram avaliados seis períodos de avaliação (aos 60, 120, 180, 240, 300 e 360 dias). Avaliou-se altura das plantas, comprimento das raízes, diâmetro do caule, índice de área foliar e matéria seca (raiz, caule, folhas) em cada período. Foi determinado o acúmulo de macronutrientes nos diferentes órgãos das plantas, bem como, o acúmulo de nutrientes em função do tempo ajustado ao modelo linear. Os resultados demonstraram que o cultivo em solução nutritiva foi eficiente na produção de mudas de jabuticabeira Sabará. Não houve diferença no crescimento e absorção de macronutrientes entre os genótipos de jabuticaba cultivados em solução nutritiva. As plantas de jabuticaba \u27Sabará\u27 acumularam (em mg planta-1) 559 de N, 45 de P, 443 de K, 363 de Ca, 59 de Mg e 82 de S. A distribuição das acumulações de macronutrientes na jabuticaba mostrou a seguinte ordem: folhas > caule> raízes

Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017 : a systematic analysis for the Global Burden of Disease Study 2017

Background: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers a useful tool for synthesising evidence on risks and risk outcome associations. With each annual GBD study, we update the GBD CRA to incorporate improved methods, new risks and risk outcome pairs, and new data on risk exposure levels and risk outcome associations. Methods: We used the CRA framework developed for previous iterations of GBD to estimate levels and trends in exposure, attributable deaths, and attributable disability-adjusted life-years (DALYs), by age group, sex, year, and location for 84 behavioural, environmental and occupational, and metabolic risks or groups of risks from 1990 to 2017. This study included 476 risk outcome pairs that met the GBD study criteria for convincing or probable evidence of causation. We extracted relative risk and exposure estimates from 46 749 randomised controlled trials, cohort studies, household surveys, census data, satellite data, and other sources. We used statistical models to pool data, adjust for bias, and incorporate covariates. Using the counterfactual scenario of theoretical minimum risk exposure level (TMREL), we estimated the portion of deaths and DALYs that could be attributed to a given risk. We explored the relationship between development and risk exposure by modelling the relationship between the Socio-demographic Index (SDI) and risk-weighted exposure prevalence and estimated expected levels of exposure and risk-attributable burden by SDI. Finally, we explored temporal changes in risk-attributable DALYs by decomposing those changes into six main component drivers of change as follows: (1) population growth; (2) changes in population age structures; (3) changes in exposure to environmental and occupational risks; (4) changes in exposure to behavioural risks; (5) changes in exposure to metabolic risks; and (6) changes due to all other factors, approximated as the risk-deleted death and DALY rates, where the risk-deleted rate is the rate that would be observed had we reduced the exposure levels to the TMREL for all risk factors included in GBD 2017. Findings: In 2017,34.1 million (95% uncertainty interval [UI] 33.3-35.0) deaths and 121 billion (144-1.28) DALYs were attributable to GBD risk factors. Globally, 61.0% (59.6-62.4) of deaths and 48.3% (46.3-50.2) of DALYs were attributed to the GBD 2017 risk factors. When ranked by risk-attributable DALYs, high systolic blood pressure (SBP) was the leading risk factor, accounting for 10.4 million (9.39-11.5) deaths and 218 million (198-237) DALYs, followed by smoking (7.10 million [6.83-7.37] deaths and 182 million [173-193] DALYs), high fasting plasma glucose (6.53 million [5.23-8.23] deaths and 171 million [144-201] DALYs), high body-mass index (BMI; 4.72 million [2.99-6.70] deaths and 148 million [98.6-202] DALYs), and short gestation for birthweight (1.43 million [1.36-1.51] deaths and 139 million [131-147] DALYs). In total, risk-attributable DALYs declined by 4.9% (3.3-6.5) between 2007 and 2017. In the absence of demographic changes (ie, population growth and ageing), changes in risk exposure and risk-deleted DALYs would have led to a 23.5% decline in DALYs during that period. Conversely, in the absence of changes in risk exposure and risk-deleted DALYs, demographic changes would have led to an 18.6% increase in DALYs during that period. The ratios of observed risk exposure levels to exposure levels expected based on SDI (O/E ratios) increased globally for unsafe drinking water and household air pollution between 1990 and 2017. This result suggests that development is occurring more rapidly than are changes in the underlying risk structure in a population. Conversely, nearly universal declines in O/E ratios for smoking and alcohol use indicate that, for a given SDI, exposure to these risks is declining. In 2017, the leading Level 4 risk factor for age-standardised DALY rates was high SBP in four super-regions: central Europe, eastern Europe, and central Asia; north Africa and Middle East; south Asia; and southeast Asia, east Asia, and Oceania. The leading risk factor in the high-income super-region was smoking, in Latin America and Caribbean was high BMI, and in sub-Saharan Africa was unsafe sex. O/E ratios for unsafe sex in sub-Saharan Africa were notably high, and those for alcohol use in north Africa and the Middle East were notably low. Interpretation: By quantifying levels and trends in exposures to risk factors and the resulting disease burden, this assessment offers insight into where past policy and programme efforts might have been successful and highlights current priorities for public health action. Decreases in behavioural, environmental, and occupational risks have largely offset the effects of population growth and ageing, in relation to trends in absolute burden. Conversely, the combination of increasing metabolic risks and population ageing will probably continue to drive the increasing trends in non-communicable diseases at the global level, which presents both a public health challenge and opportunity. We see considerable spatiotemporal heterogeneity in levels of risk exposure and risk-attributable burden. Although levels of development underlie some of this heterogeneity, O/E ratios show risks for which countries are overperforming or underperforming relative to their level of development. As such, these ratios provide a benchmarking tool to help to focus local decision making. Our findings reinforce the importance of both risk exposure monitoring and epidemiological research to assess causal connections between risks and health outcomes, and they highlight the usefulness of the GBD study in synthesising data to draw comprehensive and robust conclusions that help to inform good policy and strategic health planning

Observation of γγ → ττ in proton-proton collisions and limits on the anomalous electromagnetic moments of the τ lepton

The production of a pair of τ leptons via photon–photon fusion, γγ → ττ, is observed for the f irst time in proton–proton collisions, with a significance of 5.3 standard deviations. This observation is based on a data set recorded with the CMS detector at the LHC at a center-of-mass energy of 13 TeV and corresponding to an integrated luminosity of 138 fb−1. Events with a pair of τ leptons produced via photon–photon fusion are selected by requiring them to be back-to-back in the azimuthal direction and to have a minimum number of charged hadrons associated with their production vertex. The τ leptons are reconstructed in their leptonic and hadronic decay modes. The measured fiducial cross section of γγ → ττ is σfid obs = 12.4+3.8 −3.1 fb. Constraints are set on the contributions to the anomalous magnetic moment (aτ) and electric dipole moments (dτ) of the τ lepton originating from potential effects of new physics on the γττ vertex: aτ = 0.0009+0.0032 −0.0031 and |dτ| < 2.9×10−17ecm (95% confidence level), consistent with the standard model

Measurements of the Electroweak Diboson Production Cross Sections in Proton-Proton Collisions at root s=5.02 TeV Using Leptonic Decays

The first measurements of diboson production cross sections in proton-proton interactions at a center-of-mass energy of 5.02 TeV are reported. They are based on data collected with the CMS detector at the LHC, corresponding to an integrated luminosity of 302 pb(-1). Events with two, three, or four charged light leptons (electrons or muons) in the final state are analyzed. The WW, WZ, and ZZ total cross sections are measured as sigma(WW) = 37:0(-5.2)(+5.5) (stat)(-2.6)(+2.7) (syst) pb, sigma(WZ) = 6.4(-2.1)(+2.5) (stat)(-0.3)(+0.5)(syst) pb, and sigma(ZZ) = 5.3(-2.1)(+2.5)(stat)(-0.4)(+0.5) (syst) pb. All measurements are in good agreement with theoretical calculations at combined next-to-next-to-leading order quantum chromodynamics and next-to-leading order electroweak accuracy

Search for lepton-flavor violating decays of the Higgs boson in the mu tau and e tau final states in proton-proton collisions at root s=13 TeV

A search is presented for lepton-flavor violating decays of the Higgs boson to mu t and et. The dataset corresponds to an integrated luminosity of 137 fb(-1) collected at the LHC in proton-proton collisions at a center-of-mass energy of 13 TeV. No significant excess has been found, and the results are interpreted in terms of upper limits on lepton-flavor violating branching fractions of the Higgs boson. The observed (expected) upper limits on the branching fractions are, respectively, B(H -> mu t) e tau) < 0.22(0.16)% at 95% confidence level.Peer reviewe

Probing effective field theory operators in the associated production of top quarks with a Z boson in multilepton final states at root s=13 TeV

Peer reviewe

Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults

Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. Methods We used data from 3663 population-based studies with 222 million participants that measured height and weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the individual and combined prevalence of underweight (BMI &lt;18·5 kg/m2) and obesity (BMI ≥30 kg/m2). For school&#x2;aged children and adolescents, we report thinness (BMI &lt;2 SD below the median of the WHO growth reference) and obesity (BMI &gt;2 SD above the median). Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and 140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%) with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and 42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents, the increases in double burden were driven by increases in obesity, and decreases in double burden by declining underweight or thinness. Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of underweight while curbing and reversing the increase in obesit