57 research outputs found

    Intercellular Diffusion of a Fluorescent Sucrose Analog via the Septal Junctions in a Filamentous Cyanobacterium

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    D.J.N. was supported by a Queen Mary University of London College studentship. M.N.M. was the recipient of an FPU (Formación del Personal Universitario) fellowship from the Spanish Government. Work in Seville was supported by grant BFU2011-22762 from Plan Nacional de Investigación, Spain, cofinanced by the European Regional Development Fund, and by Plan Andaluz de Investigación, Regional Government of Andalucía (grant P10-CVI-6665). Research in Tübingen was supported by the Deutsche Forschungsgemeinschaft (SFB766)

    Branching and intercellular communication in the Section V cyanobacterium Mastigocladus laminosus, a complex multicellular prokaryote

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    This work was supported by a college studentship of Queen Mary University of London, and the College Central Research Fund. Work in Seville was supported by Grant No. BFU2011-22762 from Plan Nacional de Investigación, Spain, co-financed by FEDER

    Experimental assessment and semi empirical estimation of frost accretion—A case study on a spine-finned inverted-V tube array evaporator

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    Present work focuses on frost accretion in a spine-finned inverted-V tube array evaporator. An experimental evaluation was performed using a standard issue, vertical top-mount, 18 cubic feet, 0.5 m3, refrigerator. Evaporator temperature distribution, inner airflow velocity, and relative humidity were measured to account for convective phenomena influencing frost distribution. Frost formation and accretion on the surface of the evaporator were visualized using thermal and microscopic imagery. The images were processed using a machine vision algorithm to measure frost thickness. Complementarily, frost density and vapor mass transfer were computed using available correlations. An estimation function was derived from the compiled data using a semi empirical approach, i.e., direct measurements and thermophysical substance properties. The resulting mathematical expression estimated the frost accretion rate within an error expectancy, RMSE, of 0.1479 and displayed a goodness-of-fit, R-Squared, of 0.9029. Based on these results, semi empirical estimation, is proposed as a viable approach to construct adequate limits for new predictions, vis-à-vis evaporator performance, ultimately reducing appliance energy consumption via implementing more effective control strategies regarding internal defrosting

    Subcellular Localization and Clues for the Function of the HetN Factor Influencing Heterocyst Distribution in Anabaena sp Strain PCC 7120

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    Research in Seville was supported by grant BFU2010-17980 from the Spanish Government, cofinanced by FEDER. L.C.-G. was the recipient of a JAE-predoc fellowship from the CSIC. D.J.N. was supported by a Queen Mary College studentship. Sequence analysis was supported in part by grant DBI-0850146 from the U.S. National Science Foundation

    Multimessenger NuEM Alerts with AMON

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    The Astrophysical Multimessenger Observatory Network (AMON), has developed a real-time multi-messenger alert system. The system performs coincidence analyses of datasets from gamma-ray and neutrino detectors, making the Neutrino-Electromagnetic (NuEM) alert channel. For these analyses, AMON takes advantage of sub-threshold events, i.e., events that by themselves are not significant in the individual detectors. The main purpose of this channel is to search for gamma-ray counterparts of neutrino events. We will describe the different analyses that make-up this channel and present a selection of recent results

    Use of anticoagulants and antiplatelet agents in stable outpatients with coronary artery disease and atrial fibrillation. International CLARIFY registry

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    Minimal information for studies of extracellular vesicles 2018 (MISEV2018):a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

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    The last decade has seen a sharp increase in the number of scientific publications describing physiological and pathological functions of extracellular vesicles (EVs), a collective term covering various subtypes of cell-released, membranous structures, called exosomes, microvesicles, microparticles, ectosomes, oncosomes, apoptotic bodies, and many other names. However, specific issues arise when working with these entities, whose size and amount often make them difficult to obtain as relatively pure preparations, and to characterize properly. The International Society for Extracellular Vesicles (ISEV) proposed Minimal Information for Studies of Extracellular Vesicles (“MISEV”) guidelines for the field in 2014. We now update these “MISEV2014” guidelines based on evolution of the collective knowledge in the last four years. An important point to consider is that ascribing a specific function to EVs in general, or to subtypes of EVs, requires reporting of specific information beyond mere description of function in a crude, potentially contaminated, and heterogeneous preparation. For example, claims that exosomes are endowed with exquisite and specific activities remain difficult to support experimentally, given our still limited knowledge of their specific molecular machineries of biogenesis and release, as compared with other biophysically similar EVs. The MISEV2018 guidelines include tables and outlines of suggested protocols and steps to follow to document specific EV-associated functional activities. Finally, a checklist is provided with summaries of key points
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