9 research outputs found

    SEAmester – South Africa’s first class afloat

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    publisher versionFrom Introduction: Marine science is a highly competitive environment. The need to improve the cohort of South African postgraduates, who would be recognised both nationally and internationally for their scientific excellence, is crucial. It is possible to attract students early on in their careers to this discipline via cutting-edge science, technology and unique field experiences. Through the engagement of students with real-life experiences such as SEAmester, universities supporting marine science postgraduate degree programmes can attract a sustainable throughput of numerically proficient students. By achieving a more quantitative and experienced input into our postgraduate degree programmes, we will, as a scientific community, greatly improve our long-term capabilities to accurately measure, model and predict the impacts of current climate change scenarios. The short-term goal is to attract and establish a cohort of proficient marine and atmospheric science graduates who will contribute to filling the capacity needs of South African marine science as a whole. The SEAmester programme, by involving researchers from across all the relevant disciplines and tertiary institutions, provides an opportunity to build a network of collaborative teaching within the marine field. In doing so, these researchers will foster and strengthen new and current collaborations between historically white and black universities (Figure 1). The long-term objective of SEAmester is to build critical mass within the marine sciences to ensure sustained growth of human capacity in marine science in South Africa – aligning closely with the current DST Research and Development strategies and the Operation Phakisa Oceans Economy initiative

    Monitoring the dynamics of the Agulhas Current System off Port Edward, Kwazulu-Natal.

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    Thesis submitted in fulfilment of the requirements for the degree Master of Technology: Oceanography in the Faculty of Applied Sciences at the Cape Peninsula University of TechnologyIn order to validate remote sensing products and to provide data for model assimilation, a real-time monitoring line consisting of three moorings was deployed across the Agulhas Current off Port Edward, South Africa. This deployment formed part of a Technology and Human Resource for Industry Programme (THRIP) funded initiative to develop a real-time mooring system capable of measuring ocean parameters in the Agulhas Current during 2011. The slope and offshore moorings displayed a distinct stratified regime within the Agulhas Current, a northeastward flowing Agulhas Undercurrent and the southwestward flowing Agulhas Current. Three major reversal events, with northeastward currents occurred on 23 July, 02 September and on 11 October 2011. All current reversals caused a decrease in current velocity. The Agulhas Undercurrent was a persistent feature and average velocities between the line of moorings ranged between 13.38 cm/s and 15.52 cm/s. The results obtained from the mooring systems were consistent in terms of velocity, direction and hydrographic properties of the Agulhas Current as described in previous literature. The low directional variability in the surface layers at the offshore mooring and dominant southwestward flow, except during reversal events indicate the strong influence of the Agulhas Current in this region. The inshore mooring showed less occurrences of the Agulhas Undercurrent if northward flow in the bottom layers was to be considered as signs of the Agulhas Undercurrent. General current characteristics as well as the characterisation of the mesoscale features affecting the coast off Port Edward was accomplished through the use of the in situ moorings. All current reversals encountered were associated with the process of vortex shedding from the Natal Bight. These events may be related to the shedding of the Durban Cyclonic Eddy from its origin in the Natal Bight. Data from the offshore mooring suggested that for monitoring Agulhas Current core dynamics, it was ideally placed as highest surface velocities were measured by this mooring system. The slope mooring recorded highest velocities within the Agulhas Undercurrent and was thus ideally placed to measure the Agulhas Undercurrent’s core. Shelf dynamics were under the influence of the Agulhas Current and northerly current reversals and were aptly recorded by the inshore mooring which was placed on the continental shelf, close to the shelf break

    The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

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    [The effect of low-dose hydrocortisone on requirement of norepinephrine and lactate clearance in patients with refractory septic shock].

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    Second asymptomatic carotid surgery trial (ACST-2) : a randomised comparison of carotid artery stenting versus carotid endarterectomy

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    Background: Among asymptomatic patients with severe carotid artery stenosis but no recent stroke or transient cerebral ischaemia, either carotid artery stenting (CAS) or carotid endarterectomy (CEA) can restore patency and reduce long-term stroke risks. However, from recent national registry data, each option causes about 1% procedural risk of disabling stroke or death. Comparison of their long-term protective effects requires large-scale randomised evidence. Methods: ACST-2 is an international multicentre randomised trial of CAS versus CEA among asymptomatic patients with severe stenosis thought to require intervention, interpreted with all other relevant trials. Patients were eligible if they had severe unilateral or bilateral carotid artery stenosis and both doctor and patient agreed that a carotid procedure should be undertaken, but they were substantially uncertain which one to choose. Patients were randomly allocated to CAS or CEA and followed up at 1 month and then annually, for a mean 5 years. Procedural events were those within 30 days of the intervention. Intention-to-treat analyses are provided. Analyses including procedural hazards use tabular methods. Analyses and meta-analyses of non-procedural strokes use Kaplan-Meier and log-rank methods. The trial is registered with the ISRCTN registry, ISRCTN21144362. Findings: Between Jan 15, 2008, and Dec 31, 2020, 3625 patients in 130 centres were randomly allocated, 1811 to CAS and 1814 to CEA, with good compliance, good medical therapy and a mean 5 years of follow-up. Overall, 1% had disabling stroke or death procedurally (15 allocated to CAS and 18 to CEA) and 2% had non-disabling procedural stroke (48 allocated to CAS and 29 to CEA). Kaplan-Meier estimates of 5-year non-procedural stroke were 2·5% in each group for fatal or disabling stroke, and 5·3% with CAS versus 4·5% with CEA for any stroke (rate ratio [RR] 1·16, 95% CI 0·86-1·57; p=0·33). Combining RRs for any non-procedural stroke in all CAS versus CEA trials, the RR was similar in symptomatic and asymptomatic patients (overall RR 1·11, 95% CI 0·91-1·32; p=0·21). Interpretation: Serious complications are similarly uncommon after competent CAS and CEA, and the long-term effects of these two carotid artery procedures on fatal or disabling stroke are comparable
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