The Featureless Transmission Spectra of Two Super-puff Planets

The Kepler mission revealed a class of planets known as "super-puffs," with masses only a few times larger than Earth's but radii larger than Neptune, giving them very low mean densities. All three of the known planets orbiting the young solar-type star Kepler 51 are super-puffs. The Kepler 51 system thereby provides an opportunity for a comparative study of the structures and atmospheres of this mysterious class of planets, which may provide clues about their formation and evolution. We observed two transits each of Kepler 51b and 51d with the Wide Field Camera 3 (WFC3) on the Hubble Space Telescope. Combining new WFC3 transit times with reanalyzed Kepler data and updated stellar parameters, we confirmed that all three planets have densities lower than 0.1 g cm⁻³. We measured the WFC3 transmission spectra to be featureless between 1.15 and 1.63 μm, ruling out any variations greater than 0.6 scale heights (assuming a H/He-dominated atmosphere), thus showing no significant water absorption features. We interpreted the flat spectra as the result of a high-altitude aerosol layer (pressure <3 mbar) on each planet. Adding this new result to the collection of flat spectra that have been observed for other sub-Neptune planets, we find support for one of the two hypotheses introduced by Crossfield & Kreidberg, that planets with cooler equilibrium temperatures have more high-altitude aerosols. We strongly disfavor their other hypothesis that the H/He mass fraction drives the appearance of large-amplitude transmission features

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy

Debris disk results from the Gemini Planet Imager Exoplanet Survey's polarimetric imaging campaign

Funding: Supported by NSF grants AST-1411868 (E.L.N., K.B.F., B.M., and J.P.), AST-141378 (G.D.), and AST-1518332 (T.M.E., R.J.D.R., J.R.G., P.K., G.D.). Supported by NASA grants NNX14AJ80G (E.L.N., B.M., F.M., and M.P.), NNX15AC89G and NNX15AD95G/NExSS (T.M.E., B.M., R.J.D.R., G.D., J.J.W, J.R.G., P.K.), NN15AB52l (D.S.), and NNX16AD44G (K.M.M.). M.R. is supported by the NSF Graduate Research Fellowship Program under grant number DGE-1752134. J.R. and R.D. acknowledge support from the Fonds de Recherche du Quèbec. J. Mazoyer’s work was performed in part under contract with the California Institute of Technology/Jet Propulsion Laboratory funded by NASA through the Sagan Fellowship Program executed by the NASA Exoplanet Science Institute. M.M.B. and J.M. were supported by NASA through Hubble Fellowship grants #51378.01-A and HST-HF2-51414.001, respectively, and I.C. through Hubble Fellowship grant HST-HF2-51405.001-A, awarded by the Space Telescope Science Institute, which is operated by AURA, for NASA, under contract NAS5-26555. K.W.D. is supported by an NRAO Student Observing Support Award SOSPA3-007. J.J.W. is supported by the Heising-Simons Foundation 51 Pegasi b postdoctoral fellowship.We report the results of a ∼4 yr direct imaging survey of 104 stars to resolve and characterize circumstellar debris disks in scattered light as part of the Gemini Planet Imager (GPI) Exoplanet Survey. We targeted nearby (≲150 pc), young (≲500 Myr) stars with high infrared (IR) excesses (LIR/L⋆ > 10-5), including 38 with previously resolved disks. Observations were made using the GPI high-contrast integral field spectrograph in H-band (1.6 μm) coronagraphic polarimetry mode to measure both polarized and total intensities. We resolved 26 debris disks and 3 protoplanetary/transitional disks. Seven debris disks were resolved in scattered light for the first time, including newly presented HD 117214 and HD 156623, and we quantified basic morphologies of five of them using radiative transfer models. All of our detected debris disks except HD 156623 have dust-poor inner holes, and their scattered-light radii are generally larger than corresponding radii measured from resolved thermal emission and those inferred from spectral energy distributions. To assess sensitivity, we report contrasts and consider causes of nondetections. Detections were strongly correlated with high IR excess and high inclination, although polarimetry outperformed total intensity angular differential imaging for detecting low-inclination disks (≲70°). Based on postsurvey statistics, we improved upon our presurvey target prioritization metric predicting polarimetric disk detectability. We also examined scattered-light disks in the contexts of gas, far-IR, and millimeter detections. Comparing H-band and ALMA fluxes for two disks revealed tentative evidence for differing grain properties. Finally, we found no preference for debris disks to be detected in scattered light if wide-separation substellar companions were present.Publisher PDFPeer reviewe

The Gemini planet imager view of the HD 32297 debris disk

Funding: M.M.B. and J.M. were supported by NASA through Hubble Fellowship grants #51378.01-A and HST-HF2-51414.001, respectively, and I.C. through Hubble Fellowship grant HST-HF2-51405.001-A, awarded by the Space Telescope Science Institute, which is operated by AURA, for NASA, under contract NAS5-26555.We present new H-band scattered light images of the HD 32297 edge-on debris disk obtained with the Gemini Planet Imager. The disk is detected in total and polarized intensity down to a projected angular separation of 0"15, or 20 au. On the other hand, the large-scale swept-back halo remains undetected, likely a consequence of its markedly blue color relative to the parent body belt. We analyze the curvature of the disk spine and estimate a radius of ≍100 au for the parent body belt, smaller than past scattered light studies but consistent with thermal emission maps of the system. We employ three different flux-preserving post-processing methods to suppress the residual starlight and evaluate the surface brightness and polarization profile along the disk spine. Unlike past studies of the system, our high-fidelity images reveal the disk to be highly symmetric and devoid of morphological and surface brightness perturbations. We find the dust scattering properties of the system to be consistent with those observed in other debris disks, with the exception of HR 4796. Finally, we find no direct evidence for the presence of a planetary-mass object in the system.Publisher PDFPeer reviewe

The First Post-Kepler Brightness Dips of KIC 8462852

We present a photometric detection of the first brightness dips of the unique variable star KIC 8462852 since the end of the Kepler space mission in 2013 May. Our regular photometric surveillance started in October 2015, and a sequence of dipping began in 2017 May continuing on through the end of 2017, when the star was no longer visible from Earth. We distinguish four main 1-2.5% dips, named "Elsie," "Celeste," "Skara Brae," and "Angkor", which persist on timescales from several days to weeks. Our main results so far are: (i) there are no apparent changes of the stellar spectrum or polarization during the dips; (ii) the multiband photometry of the dips shows differential reddening favoring non-grey extinction. Therefore, our data are inconsistent with dip models that invoke optically thick material, but rather they are in-line with predictions for an occulter consisting primarily of ordinary dust, where much of the material must be optically thin with a size scale <<1um, and may also be consistent with models invoking variations intrinsic to the stellar photosphere. Notably, our data do not place constraints on the color of the longer-term "secular" dimming, which may be caused by independent processes, or probe different regimes of a single process