A numerical analysis of the plastic wake influence on plasticity induced crack closure

Fatigue crack closure has been studied by means of finite element method since long time ago. Most work has been performed considering bi-dimensional models. Lately, the use of threedimensional models has been extended. Nevertheless, the methodology employed has been taken from that developed for bi-dimensional cases. There are a great number of previous bi-dimensional studies which analyse different numerical parameters and optimise them. The current computational capabilities allow a comprehensive study of the influence of the different modelling parameters in a similar way to those studies carried out with bidimensional models, with the advantage, that the evolution along the thickness of the analysed parameters can be taken into consideration. In particular, one of the key issues is related to the plastic wake length which is developed during the previous loading cycles. This residual stresses have a great influence on the crack opening and closure values. As the numerical analysis are complex and computationally expensive, the length of the simulated wake is a critical parameter. In this work, a comprehensive study of the effect of the plastic wake in fatigue crack closure is made. On this purpose, a CT aluminium specimen has been modelled three-dimensionally and several calculations have been made in order to evaluate the influence of the simulated plastic wake length. The numerical analysis is made in terms of crack closure and opening values as in terms of the stress and strain fields near the crack front.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Through thickness evolution of crack tip plasticity

Experimental methods to measure fracture mechanics parameters tend to provide information from or about the surface of cracked components. However, information about the interior of the component is key to understanding the mechanisms governing the damage processes at a crack tip for both fatigue and fracture events. In this work we present a detailed numerical analysis of the evolution of the plastic zone through the thickness of an aluminium alloy specimen. This is done by means of ultra-fine non- linear finite element models. The simulated results are compared with experimental displacement data measured optically from the surface of the specimen.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Análisis numérico bidimensional del efecto de campos de tensiones no uniformes en grietas en modo mixto

La probeta con taladro centrado es un tipo de geometría a partir de la cual las grietas se propagan con frecuencia. En algunos casos, el análisis combinado de carga en modo mixto I y II tiene cierta relevancia industrial. Por este motivo, se ha realizado un análisis numérico bidimensional de una grieta que emana de un taladro en una placa de aleación de aluminio. Se han calculado las áreas plastificadas y los desplazamientos alrededor de la grieta para siete estados de carga biaxial diferentes. Para ello, se ha modificado el ángulo de aplicación de la carga desde 23.4° (modos I+II) hasta 90° (modo I puro) considerando incrementos de 11.1°, y se ha mantenido constante el valor nominal de carga. Con el objetivo de obtener áreas más precisas, se ha utilizado un análisis de elementos finitos basado en el submodelado. Posteriormente, para contrastar los resultados, se han comparado los campos de desplazamiento en la superficie alrededor de la grieta con los resultados obtenidos de forma experimental usando la técnica de correlación de imágenes. Después de la validación del modelo, se ha estudiado la evolución de las zonas plastificadas en condiciones de tensión y deformación plana para diferentes valores de carga nominal.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Quantum coherent control of highly multipartite continuous-variable entangled states by tailoring parametric interactions

The generation of continuous-variable multipartite entangled states is important for several protocols of quantum information processing and communication, such as one-way quantum computation or controlled dense coding. In this article we theoretically show that multimode optical parametric oscillators can produce a great variety of such states by an appropriate control of the parametric interaction, what we accomplish by tailoring either the spatio-temporal shape of the pump, or the geometry of the nonlinear medium. Specific examples involving currently available optical parametric oscillators are given, hence showing that our ideas are within reach of present technology.Comment: 14 pages, 5 figure

CIBERER : Spanish national network for research on rare diseases: A highly productive collaborative initiative

Altres ajuts: Instituto de Salud Carlos III (ISCIII); Ministerio de Ciencia e Innovación.CIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). This innovative research structure comprises 11 different specific areas dedicated to the main public health priorities in the National Health System. CIBERER, the thematic area of CIBER focused on rare diseases (RDs) currently consists of 75 research groups belonging to universities, research centers, and hospitals of the entire country. CIBERER's mission is to be a center prioritizing and favoring collaboration and cooperation between biomedical and clinical research groups, with special emphasis on the aspects of genetic, molecular, biochemical, and cellular research of RDs. This research is the basis for providing new tools for the diagnosis and therapy of low-prevalence diseases, in line with the International Rare Diseases Research Consortium (IRDiRC) objectives, thus favoring translational research between the scientific environment of the laboratory and the clinical setting of health centers. In this article, we intend to review CIBERER's 15-year journey and summarize the main results obtained in terms of internationalization, scientific production, contributions toward the discovery of new therapies and novel genes associated to diseases, cooperation with patients' associations and many other topics related to RD research

Global surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2)

BACKGROUND: Worldwide data for cancer survival are scarce. We aimed to initiate worldwide surveillance of cancer survival by central analysis of population-based registry data, as a metric of the effectiveness of health systems, and to inform global policy on cancer control. METHODS: Individual tumour records were submitted by 279 population-based cancer registries in 67 countries for 25·7 million adults (age 15-99 years) and 75,000 children (age 0-14 years) diagnosed with cancer during 1995-2009 and followed up to Dec 31, 2009, or later. We looked at cancers of the stomach, colon, rectum, liver, lung, breast (women), cervix, ovary, and prostate in adults, and adult and childhood leukaemia. Standardised quality control procedures were applied; errors were corrected by the registry concerned. We estimated 5-year net survival, adjusted for background mortality in every country or region by age (single year), sex, and calendar year, and by race or ethnic origin in some countries. Estimates were age-standardised with the International Cancer Survival Standard weights. FINDINGS: 5-year survival from colon, rectal, and breast cancers has increased steadily in most developed countries. For patients diagnosed during 2005-09, survival for colon and rectal cancer reached 60% or more in 22 countries around the world; for breast cancer, 5-year survival rose to 85% or higher in 17 countries worldwide. Liver and lung cancer remain lethal in all nations: for both cancers, 5-year survival is below 20% everywhere in Europe, in the range 15-19% in North America, and as low as 7-9% in Mongolia and Thailand. Striking rises in 5-year survival from prostate cancer have occurred in many countries: survival rose by 10-20% between 1995-99 and 2005-09 in 22 countries in South America, Asia, and Europe, but survival still varies widely around the world, from less than 60% in Bulgaria and Thailand to 95% or more in Brazil, Puerto Rico, and the USA. For cervical cancer, national estimates of 5-year survival range from less than 50% to more than 70%; regional variations are much wider, and improvements between 1995-99 and 2005-09 have generally been slight. For women diagnosed with ovarian cancer in 2005-09, 5-year survival was 40% or higher only in Ecuador, the USA, and 17 countries in Asia and Europe. 5-year survival for stomach cancer in 2005-09 was high (54-58%) in Japan and South Korea, compared with less than 40% in other countries. By contrast, 5-year survival from adult leukaemia in Japan and South Korea (18-23%) is lower than in most other countries. 5-year survival from childhood acute lymphoblastic leukaemia is less than 60% in several countries, but as high as 90% in Canada and four European countries, which suggests major deficiencies in the management of a largely curable disease. INTERPRETATION: International comparison of survival trends reveals very wide differences that are likely to be attributable to differences in access to early diagnosis and optimum treatment. Continuous worldwide surveillance of cancer survival should become an indispensable source of information for cancer patients and researchers and a stimulus for politicians to improve health policy and health-care systems

Measurements of differential production cross sections for a Z boson in association with jets in pp collisions at root s=8 TeV

Peer reviewe

Long-range Angular Correlations On The Near And Away Side In P-pb Collisions At √snn=5.02 Tev

7191/Mar294