Energy efficient engine. Low pressure turbine test hardware detailed design report

The low pressure turbine for the energy efficient engine is a five-stage configuration with moderate aerodynamic loading incorporating advanced features of decambered airfoils and extended blade overlaps at platforms and shrouds. Mechanical integrity of 18,000 hours on flowpath components and 36,000 hours on all other components is achieved along with no aeromechanical instabilities within the steady-state operating range. Selection of a large number (156) of stage 4 blades, together with an increased stage 4 vane-to-blade gap, assists in achieving FAR 36 acoustic goals. Active clearance control (ACC) of gaps at blade tips and interstage seals is achieved by fan air cooling judiciously applied at responsive locations on the casing. This ACC system is a major improvement in preventing deterioration of the 0.0381 cm (0.015 in.) clearances required to meet the integrated-core/low-spool turbine efficiency goal of 91.1% and the light propulsion system efficiency goal of 91.7%

The uses of amateurs : travel writing as a tool of second language acquisition research

In order for second language acquisition (SLA) research to access the ‘learner-internal functions’ of SLA, methodologies of introspective research have arisen, including ‘diary studies’ and ‘language learner histories’. These have been found to yield valuable data about SLA (particularly in respect of affective factors and learning strategies), and are most rewarding when they approximate to quasi-literary modes of self-presentation: highly personalized and richly contextualized. This article proposes that the body of data that has accumulated from this initiative could be further expanded by including non-specialist accounts of language learning which share many of the conditions and features of diary studies, specifically works of travel literature in which part of the travellers’ experience is learning local languages. The article first attempts to illustrate this common ground by means of comparative samples, and then demonstrates from further texts how travel writing, though not produced by SLA specialists, can be analysed in terms of SLA theory so as to yield its own insights that not only corroborate what the specialist diary studies have revealed, but also supplement or challenge them. The article concludes that there is in this growing body of work a hitherto untapped resource of SLA research that awaits more sustained attention.http://www.tandfonline.com/loi/racr202016-12-31hb2016Englis

Hot-Film and Hot-Wire Anemometry for a Boundary Layer Active Flow Control Test

Unsteady active flow control (AFC) has been used experimentally for many years to minimize bluff-body drag. This technology could significantly improve performance of rotorcraft by cleaning up flow separation. It is important, then, that new actuator technologies be studied for application to future vehicles. A boundary layer wind tunnel was constructed with a 1ft-x-3ft test section and unsteady measurement instrumentation to study how AFC manipulates the boundary layer to overcome adverse pressure gradients and flow separation. This unsteady flow control research requires unsteady measurement methods. In order to measure the boundary layer characteristics, both hot-wire and hot-film Constant Temperature Anemometry is used. A hot-wire probe is mounted in the flow to measure velocity while a hot-film array lays on the test surface to measure skin friction. Hot-film sensors are connected to an anemometer, a Wheatstone bridge circuit with an output that corresponds to the dynamic flow response. From this output, the time varying flow field, turbulence, and flow reversal can be characterized. Tuning the anemometers requires a fan test on the hot-film sensors to adjust each output. This is a delicate process as several variables drastically affect the data, including control resistance, signal input, trim, and gain settings

The ultra-sensitive electrical detection of spin Rabi oscillation at paramagnetic defects

A short review of the pulsed electrically detected magnetic resonance (pEDMR) experiment is presented. PEDMR allows the highly sensitive observation of coherent electron spin motion of charge carriers and defects in semiconductors by means of transient current measurements. The theoretical foundations, the experimental implementation, its sensitivity and its potential with regard to the investigation of electronic transitions in semiconductors are discussed. For the example of the P_b center at the crystalline silicon (111) to silicon dioxide interface it is shown experimentally how one can detect spin Rabi-oscillation, its dephasing, coherence decays and spin-coupling effects.Comment: The manuscript has been submitted for journal publicatio

The key role of CD40 ligand in overcoming tumor-induced dendritic cell dysfunction

Overcoming dendritic cell (DC) dysfunction is a prerequisite for successful active immunotherapy against breast cancer. CD40 ligand (CD40L), a key molecule in the interface between T-lymphocytes and DCs, seems to be instrumental in achieving that goal. Commenting on our data that CD40L protects circulating DCs from apoptosis induced by breast tumor products, Lenahan and Avigan highlighted the potential of CD40L for immunotherapy. We expand on that argument by pointing to additional findings that CD40L not only rescues genuine DCs but also functionally improves populations of immature antigen-presenting cells that fill the DC compartment in patients with breast cancer

Lithium in the aragonite skeletons of massive Porites corals: A new tool to reconstruct tropical sea surface temperatures

Previous studies have demonstrated the potential for the Li content of coral aragonite to record information about environmental conditions, but no detailed study of tropical corals exists. Here we present the Li and Mg to Ca ratios at a bimonthly to monthly resolution over 25 years in two modern Porites corals, the genus most often used for paleoclimate reconstructions in the tropical Indo-Pacific. A strong relationship exists between coral Li/Ca and locally measured SST, indicating that coral Li/Ca can be used to reconstruct tropical SST variations. However, Li/Ca ratios of the skeleton deposited during 1979-1980 do not track local SST well and are anomalously high in places. The Mg/Ca ratios of this interval are also anomalously high, and we suggest Li/Ca can be used to reconstruct tropical SST only when Mg/Ca data are used to carefully screen for relatively rare biological effects. Mg/Li or Li/Mg ratios provide little advantage over Li/Ca ratios, except that the slope of the Li/Mg temperature relationship is more similar between the two corals. The Mg/Li temperature relationship for the coral that experienced a large temperature range is similar to that found for cold water corals and aragonitic benthic foraminifera in previous studies. The comparison with data from other biogenic aragonites suggests the relationship between Li/Mg and water temperature can be described by a single exponential relationship. Despite this hint at an overarching control, it is clear that biological processes strongly influence coral Li/Ca, and more calibration work is required before widely applying the prox

The genetic architecture of the human cerebral cortex

The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson's disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder