691 research outputs found

    Deep Learning-based Limited Feedback Designs for MIMO Systems

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    We study a deep learning (DL) based limited feedback methods for multi-antenna systems. Deep neural networks (DNNs) are introduced to replace an end-to-end limited feedback procedure including pilot-aided channel training process, channel codebook design, and beamforming vector selection. The DNNs are trained to yield binary feedback information as well as an efficient beamforming vector which maximizes the effective channel gain. Compared to conventional limited feedback schemes, the proposed DL method shows an 1 dB symbol error rate (SER) gain with reduced computational complexity.Comment: to appear in IEEE Wireless Commun. Let

    The Universe is worth 64364^3 pixels: Convolution Neural Network and Vision Transformers for Cosmology

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    We present a novel approach for estimating cosmological parameters, Ωm\Omega_m, σ8\sigma_8, w0w_0, and one derived parameter, S8S_8, from 3D lightcone data of dark matter halos in redshift space covering a sky area of 40∘×40∘40^\circ \times 40^\circ and redshift range of 0.3<z<0.80.3 < z < 0.8, binned to 64364^3 voxels. Using two deep learning algorithms, Convolutional Neural Network (CNN) and Vision Transformer (ViT), we compare their performance with the standard two-point correlation (2pcf) function. Our results indicate that CNN yields the best performance, while ViT also demonstrates significant potential in predicting cosmological parameters. By combining the outcomes of Vision Transformer, Convolution Neural Network, and 2pcf, we achieved a substantial reduction in error compared to the 2pcf alone. To better understand the inner workings of the machine learning algorithms, we employed the Grad-CAM method to investigate the sources of essential information in activation maps of the CNN and ViT. Our findings suggest that the algorithms focus on different parts of the density field and redshift depending on which parameter they are predicting. This proof-of-concept work paves the way for incorporating deep learning methods to estimate cosmological parameters from large-scale structures, potentially leading to tighter constraints and improved understanding of the Universe.Comment: 23 pages, 10 figure

    No-search focus prediction at the single cell level in digital holographic imaging with deep convolutional neural network

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    Digital propagation of an off-axis hologram can provide the quantitative phase-contrast image if the exact distance between the sensor plane (such as CCD) and the reconstruction plane is correctly provided. In this paper, we present a deep-learning convolutional neural network with a regression layer as the top layer to estimate the best reconstruction distance. The experimental results obtained using microsphere beads and red blood cells show that the proposed method can accurately predict the propagation distance from a filtered hologram. The result is compared with the conventional automatic focus-evaluation function. Additionally, our approach can be utilized at the single-cell level, which is useful for cell-to-cell depth measurement and cell adherent studies. © 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement.1

    Acute Inhibition of Selected Membrane-Proximal Mouse T Cell Receptor Signaling by Mitochondrial Antagonists

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    T cells absorb nanometric membrane vesicles, prepared from plasma membrane of antigen presenting cells, via dual receptor/ligand interactions of T cell receptor (TCR) with cognate peptide/major histocompatibility complex (MHC) plus lymphocyte function-associated antigen 1 (LFA-1) with intercellular adhesion molecule 1. TCR-mediated signaling for LFA-1 activation is also required for the vesicle absorption. Exploiting those findings, we had established a high throughput screening (HTS) platform and screened a library for isolation of small molecules inhibiting the vesicle absorption. Follow-up studies confirmed that treatments (1 hour) with various mitochondrial antagonists, including a class of anti-diabetic drugs (i.e., Metformin and Phenformin), resulted in ubiquitous inhibition of the vesicle absorption without compromising viability of T cells. Further studies revealed that the mitochondrial drug treatments caused impairment of specific membrane-proximal TCR signaling event(s). Thus, activation of Akt and PLC-Îł1 and entry of extracellular Ca2+ following TCR stimulation were attenuated while polymerization of monomeric actins upon TCR triggering progressed normally after the treatments. Dynamic F-actin rearrangement concurring with the vesicle absorption was also found to be impaired by the drug treatments, implying that the inhibition by the drug treatments of downstream signaling events (and the vesicle absorption) could result from lack of directional relocation of signaling and cell surface molecules. We also assessed the potential application of mitochondrial antagonists as immune modulators by probing effects of the long-term drug treatments (24 hours) on viability of resting primary T cells and cell cycle progression of antigen-stimulated T cells. This study unveils a novel regulatory mechanism for T cell immunity in response to environmental factors having effects on mitochondrial function

    Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

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    Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð„with constraintsð ð ð„ „ ðandðŽð„ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

    Search for supersymmetry in events with one lepton and multiple jets in proton-proton collisions at root s=13 TeV

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    Measurement of the top quark forward-backward production asymmetry and the anomalous chromoelectric and chromomagnetic moments in pp collisions at √s = 13 TeV

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    Abstract The parton-level top quark (t) forward-backward asymmetry and the anomalous chromoelectric (d̂ t) and chromomagnetic (Ό̂ t) moments have been measured using LHC pp collisions at a center-of-mass energy of 13 TeV, collected in the CMS detector in a data sample corresponding to an integrated luminosity of 35.9 fb−1. The linearized variable AFB(1) is used to approximate the asymmetry. Candidate t t ÂŻ events decaying to a muon or electron and jets in final states with low and high Lorentz boosts are selected and reconstructed using a fit of the kinematic distributions of the decay products to those expected for t t ÂŻ final states. The values found for the parameters are AFB(1)=0.048−0.087+0.095(stat)−0.029+0.020(syst),Ό̂t=−0.024−0.009+0.013(stat)−0.011+0.016(syst), and a limit is placed on the magnitude of | d̂ t| &lt; 0.03 at 95% confidence level. [Figure not available: see fulltext.

    Measurement of t(t)over-bar normalised multi-differential cross sections in pp collisions at root s=13 TeV, and simultaneous determination of the strong coupling strength, top quark pole mass, and parton distribution functions

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