193 research outputs found

    Degenerative Lumbar Stenosis: Update

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    We present a literature review of the diagnosis and treatment of acquired lumbar spinal stenosis (LS), with a brief description of new surgical techniques. LS is the most common cause of spinal surgery in individuals older than 65 years of age. Neurogenic claudication and radiculopathy result from compression of the cauda equina and lumbosacral nerve roots by degenerated spinal elements. Surgical decompression is a well established treatment for patients with refractory, or moderate to severe clinical symptoms. However, the variety of surgical options is vast. New techniques have been developed with the goal of increasing long term functional outcomes. In this article we review lumbar decompression and fusion as treatment options for LS but also present other recent developments. Prospective long term studies are necessary to know which procedures would result in optimal patient outcome.672 B553558Verbiest, H., Neurogenic intermittent claudication in cases with absolute and relative stenosis of the lumbar vertebral canal (ASLC and RSLC), in cases with narrow lumbar intervertebral foramina, and in cases with both entities (1973) Clin Neurosurg, 20, pp. 204-214Boden, S.D., Davis, D.O., Dina, T.S., Patronas, N.J., Wiesel, S.W., Abnormal magnetic-resonance scans of the lumbar spine in asymptomatic subjects. a prospective investigation (1990) Journal of Bone and Joint Surgery - Series a, 72 (3), pp. 403-408Ciol, M.A., Deyo, R.A., Howell, E., Kreif, S., An assessment of surgery for spinal stenosis: Time trends, geographic variations, complications, and reoperations (1996) Journal of the American Geriatrics Society, 44 (3), pp. 285-290Kirkaldy-Willis, W.H., Wedge, J.H., Yong-Hing, K., Pathology and pathogenesis of lumbar spondylosis and stenosis (1978) Spine, 3, pp. 319-328Yong-Hing, K., Kirkaldy-Willis, W.H., The pathophysiology of degenerative disease of the lumbar spine (1983) Orthop Clin North Am, 14, pp. 491-504Sheehan, J.M., Shaffrey, C.I., Jane Sr., J.A., Degenerative lumbar stenosis: The neurosurgical perspective (2001) Clin Orthop Relat Res, 384, pp. 61-74Katz, J.N., Harris, M.B., Lumbar spinal stenosis (2008) N Engl J Med, 358, pp. 818-825Jane Jr., J.A., Di Pierro, C.G., Helm, G.A., Shaffrey, C.I., Jane Sr., J.A., Acquired lumbar stenosis: Topic review and a case series (1997) Neurosurg Focus, 3, pp. E11Jespersen, S.M., Hansen, E.S., Hoy, K., Christensen, K.O., Lindblad, B.E., Ahrensberg, J., Bunger, C., Two-level spinal stenosis in minipigs: Hemodynamic effects of exercise (1995) Spine, 20 (24), pp. 2765-2773Deburge, A., Morvan, G., L'imagerie dans les sténoses du canal lombaire (1990) Rev Chir Orthop, 76, pp. 45-49Fairbank, J.C.T., Pinsent, P.B., The Oswestry Disability Index (2000) Spine, 25, pp. 2940-2953Kenna, C., Murtagh, J., Patrick or fabere test to test hip and sacroiliac joint disorders (1989) Aust Fam Physician, 18, p. 375Joaquim, A.F., Abordagem inicial do paciente com mielopatia aguda não compressiva (2007) Rev Bras Medicina, 64, pp. 164-168Joaquim, A.F., Maturana, F.A.P., Anderle, D.V., Zambelli, H.J.L., Maldaun, M.V.C., Metástases na coluna vertebral (2007) Rev Neurocienc, 15, pp. 240-245Glassman, S.D., Bridwell, K., Dimar, J.R., Horton, W., Berven, S., Schwab, F., The impact of positive sagittal balance in adult spinal deformity (2005) Spine, 30 (18), pp. 2024-2029. , DOI 10.1097/01.brs.0000179086.30449.96Videman, T., Malmivaara, A., Mooney, V., The value of axial view in assessing discograms. An experimental study with cadavers (1987) Spine, 12 (3), pp. 299-304Nardin, R.A., Patel, M.R., Gudas, T.F., Rutkove, S.B., Raynor, E.M., EMG and MRI in the evaluation of radiculopathy (1999) Muscle Nerve, 22, pp. 151-155Dumitru, D., Zwarts, M.J., Radiculopathies (2002) Electrodiagnostic Medicine. 2nd Ed., pp. 757-758. , Dumitru D, Amato AA, Zwarts MJ (Eds). Philadelphia: Hanley and BelfusHaig, A.J., Tong, H.C., Yamakawa, K.S., The sensitivity and specity of electrodiagnostic testing for the clinical syndrome of lumbar spinal stenosis (2005) Spine, 30, pp. 2667-2676Atlas, S.J., Keller, R.B., Robson, D., Deyo, R.A., Singer, D.E., Surgical and nonsurgical management of lumbar spinal stenosis: Four-year outcomes from the Maine lumbar spine study (2000) Spine, 25 (5), pp. 556-562. , DOI 10.1097/00007632-200003010-00005Simotas, A.C., Dorey, F.J., Hansraj, K.K., Cammisa Jr., F., Nonoperative treatment for lumbar spinal stenosis: Clinical and outcome results and a 3-year survivorship analysis (2000) Spine, 25, pp. 197-204Johnsson, K.-E., Rosen, I., Uden, A., The natural course of lumbar spinal stenosis (1993) Acta Orthopaedica Scandinavica, Supplement, 64 (251), pp. 67-68Whitman, J.M., Flynn, T.W., Childs, J.D., A comparison between two physical therapy treatment programs for patients with lumbar spinal stenosis: A randomized clinical trial (2006) Spine, 31, pp. 2541-2549Armon, C., Argoff, C.E., Samuels, J., Backonja, M.-M., Assessment: Use of epidural steroid injections to treat radicular lumbosacral pain: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology (2007) Neurology, 68 (10), pp. 723-729. , DOI 10.1212/01.wnl.0000256734.34238.e7, PII 0000611420070306000007Friedly, J., Chan, L., Deyo, R., Increases in lumbosacral injections in the medicare population 1994 to 2001 (2007) Spine, 32, pp. 1754-1760Weinstein, J.N., Tosteson, T.D., Lurie, J.D., Surgical versus nonsurgical therapy for lumbar spinal stenosis (2008) N Engl J Med, 358, pp. 794-810. , SPORT InvestigatorsMalmivaara, A., Slatis, P., Heliovaara, M., Sainio, P., Kinnunen, H., Kankare, J., Dalin-Hirvonen, N., Hurri, H., Surgical or nonoperative treatment for lumbar spinal stenosis? a randomized controlled trial (2007) Spine, 32 (1), pp. 1-8. , DOI 10.1097/01.brs.0000251014.81875.6d, PII 0000763220070101000002Oertel, M.F., Ryang, Y.-M., Korinth, M.C., Gilsbach, J.M., Rohde, V., Long-term results of microsurgical treatment of lumbar spinal stenosis by unilateral laminotomy for bilateral decompression (2006) Neurosurgery, 59 (6), pp. 1264-1269. , DOI 10.1227/01.NEU.0000245616.32226.58, PII 0000612320061200000013Resnick, D.K., Choudhri, T.F., Dailey, A.T., Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 10: Fusion following decompression in patients with stenosis without spondylolisthesis (2005) J Neurosurg Spine, 2, pp. 686-691Yone, K., Sakou, T., Kawauchi, Y., Yamaguchi, M., Yanase, M., Indication of fusion for lumbar spinal stenosis in elderly patients and its significance (2006) Spine, 21, pp. 242-248Fox, M.W., Onofrio, B.M., Hanssen, A.D., Clinical outcomes and radiological instability following decompressive lumbar laminectomy for degenerative spinal stenosis: A comparison of patients undergoing concomitant arthrodesis versus decompression alone (1996) J Neurosurg, 85, pp. 793-802Herkowitz, H.N., Kurz, L.T., Degenerative lumbar spondylolisthesis with spinal stenosis: A prospective study comparing decompression with decompression and intertransverse process arthrodesis (1991) J Bone Joint Surg Am, 73, pp. 802-808Katz, J.N., Dalgas, M., Stucki, G., Degenerative lumbar spinal stenosis: Diagnostic value of the history and physical examination (1995) Arthritis Rheum, 38, pp. 1236-1241Katz, J.N., Lipson, S.J., Lew, R.A., Lumbar laminectomy alone or with instrumented or noninstrumented arthrodesis in degenerative lumbar spinal stenosis: Patient selection, costs, and surgical outcomes (1997) Spine, 22, pp. 1123-1131Selby, D.K., Gill, K., Blumenthal, S.L., Fusion of the lumbar spine (1990) Neurological Surgery. 3rd Ed., pp. 2785-2804. , Youmans JR (Ed). Philadelphia: WB SaundersHackenberg, L., Halm, H., Bullmann, V., Vieth, V., Schneider, M., Liljenqvist, U., Transforaminal lumbar interbody fusion: A safe technique with satisfactory three to five year results (2005) European Spine Journal, 14 (6), pp. 551-558. , DOI 10.1007/s00586-004-0830-1Pavlov, P.W., Meijers, H., Van Limbeek, J., Jacobs, W.C.H., Lemmens, J.A.M., Obradov-Rajic, M., De Kleuver, M., Good outcome and restoration of lordosis after anterior lumbar interbody fusion with additional posterior fixation (2004) Spine, 29 (17), pp. 1893-1899. , DOI 10.1097/01.brs.0000137067.68630.70Periasamy, K., Shah, K., Wheelwright, E.F., Posterior lumbar interbody fusion using cages, combined with instrumented posterolateral fusion: A study of 75 cases (2008) Acta Orthop Belg, 74, pp. 240-248Salehi, S.A., Tawk, R., Ganju, A., Lamarca, F., Liu, J.C., Ondra, S.L., Sonntag, V.K.H., Frempong-Boadu, A.K., Transforaminal Lumbar Interbody Fusion: Surgical Technique and Results in 24 Patients (2004) Neurosurgery, 54 (2), pp. 368-374Hsieh, P.C., Koski, T.R., O'Shaughnessy, B.A., Anterior lumbar interbody fusion in comparison with transforaminal lumbar interbody fusion: Implications for the restoration of foraminal height, local disc angle, lumbar lordosis, and sagittal balance (2007) J Neurosurg Spine, 7, pp. 379-386Ozgur, B.M., Aryan, H.E., Pimenta, L., Taylor, W.R., Extreme Lateral Interbody Fusion (XLIF): A novel surgical technique for anterior lumbar interbody fusion (2006) Spine J, 6, pp. 435-443Ahlmann, E., Patzakis, M., Roidis, N., Shepherd, L., Holtom, P., Comparison of anterior and posterior iliac crest bone grafts in terms of harvest-site morbidity and functional outcomes (2002) Journal of Bone and Joint Surgery - Series a, 84 (5), pp. 716-720+Adv46Zipfel, G.J., Guiot, B.H., Fessler, R.G., Bone grafting (2003) Neurosurg Focus, 14, pp. E8Schizas, C., Triantafyllopoulos, D., Kosmopoulos, V., Tzinieris, N., Stafylas, K., Posterolateral lumbar spine fusion using a novel demineralized bone matrix: A controlled case pilot study (2008) Arch Orthop Trauma Surg, 128, pp. 621-625Boden, S.D., Davis, D.O., Dina, T.S., Patronas, N.J., Wiesel, S.W., Abnormal magnetic-resonance scans of the lumbar spine in asymptomatic subjects. a prospective investigation (1990) Journal of Bone and Joint Surgery - Series a, 72 (3), pp. 403-408Hsu, W.K., Wang, J.C., The use of bone morphogenetic protein in spine fusion (2008) Spine J, 8, pp. 419-425Shields, L.B., Raque, G.H., Glassman, S.D., Adverse effects associated with high-dose recombinant human bone morphogenetic protein-2 use in anterior cervical spine fusion (2006) Spine, 31, pp. 542-547Glassman, S.D., Carreon, L., Djurasovic, M., Campbell, M.J., Puno, R.M., Johnson, J.R., Dimar, J.R., Posterolateral lumbar spine fusion with INFUSE bone graft (2007) Spine Journal, 7 (1), pp. 44-49. , DOI 10.1016/j.spinee.2006.06.381, PII S1529943006006930Shim, C.S., Lee, S.H., Shin, H.D., Charite versus ProDisc: A comparative study of a minimun 3-year follow-up (2007) Spine, 32, pp. 1012-1018Guyer, R.D., McAfee, P.C., Hochschuler, S.H., Prospective randomized study of the Charite artificial disc: Data from two investigational centers (2004) Spine J, 4, pp. 252-259Andeson, P.A., Tribus, C.B., Kitchel, S.H., Treatment of neurogenic claudication by interspinous decompression: Application of the X STOP device in patients with lumbar degenerative spondylolisthesis (2006) J Neurosurg Spine, 4, pp. 463-471Kondrashov, D.G., Hannibal, M., Hsu, K.Y., Zucherman, J.F., Interspinous process decompression with the X-STOP device for lumbar spinal stenosis: A 4-year follow-up study (2006) Journal of Spinal Disorders and Techniques, 19 (5), pp. 323-327. , DOI 10.1097/01.bsd.0000211294.67508.3b, PII 0002472020060700000004Welch, W.C., Cheng, B.C., Awad, T.E., Clinical outcomes of the Dynesys dynamic neutralization system: 1-year preliminary results (2007) Neurosurg Focus, 22, pp. E8Siepe, C.J., Mayer, H.M., Wiechert, K., Korge, A., Clinical results of total lumbar disc replacement with ProDisc II: Three-year results for different indications (2006) Spine, 31 (17), pp. 1923-1932. , DOI 10.1097/01.brs.0000228780.06569.e8, PII 000076322006080100000

    Observation of Orbitally Excited B_s Mesons

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    We report the first observation of two narrow resonances consistent with states of orbitally excited (L=1) B_s mesons using 1 fb^{-1} of ppbar collisions at sqrt{s} = 1.96 TeV collected with the CDF II detector at the Fermilab Tevatron. We use two-body decays into K^- and B^+ mesons reconstructed as B^+ \to J/\psi K^+, J/\psi \to \mu^+ \mu^- or B^+ \to \bar{D}^0 \pi^+, \bar{D}^0 \to K^+ \pi^-. We deduce the masses of the two states to be m(B_{s1}) = 5829.4 +- 0.7 MeV/c^2 and m(B_{s2}^*) = 5839.7 +- 0.7 MeV/c^2.Comment: Version accepted and published by Phys. Rev. Let

    Measurement of the ttbar Production Cross Section in ppbar collisions at sqrt s = 1.96 TeV in the All Hadronic Decay Mode

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    We report a measurement of the ttbar production cross section using the CDF-II detector at the Fermilab Tevatron. The analysis is performed using 311 pb-1 of ppbar collisions at sqrt(s)=1.96 TeV. The data consist of events selected with six or more hadronic jets with additional kinematic requirements. At least one of these jets must be identified as a b-quark jet by the reconstruction of a secondary vertex. The cross section is measured to be sigma(tbart)=7.5+-2.1(stat.)+3.3-2.2(syst.)+0.5-0.4(lumi.) pb, which is consistent with the standard model prediction.Comment: By CDF collaboratio

    Search for long-lived doubly charged Higgs bosons in p(p)over-bar collisions at root s=1.96 TeV

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    We present a search for long-lived doubly charged Higgs bosons (H+/-+/-), with signatures of high ionization energy loss and muonlike penetration. We use 292 pb(-1) of data collected in p (p) over bar collisions at root s=1.96 TeV by the CDF II detector at the Fermilab Tevatron. Observing no evidence of long-lived doubly charged particle production, we exclude H-L(+/-+/-) and H-R(+/-+/-) bosons with masses below 133 GeV/c(2) and 109 GeV/c(2), respectively. In the degenerate case we exclude H+/-+/- mass below 146 GeV/c(2). All limits are quoted at the 95% confidence level

    Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020

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    We show the distribution of SARS-CoV-2 genetic clades over time and between countries and outline potential genomic surveillance objectives. We applied three available genomic nomenclature systems for SARS-CoV-2 to all sequence data from the WHO European Region available during the COVID-19 pandemic until 10 July 2020. We highlight the importance of real-time sequencing and data dissemination in a pandemic situation. We provide a comparison of the nomenclatures and lay a foundation for future European genomic surveillance of SARS-CoV-2.Peer reviewe

    Search for chargino-neutralino production in ppbar collisions at sqrt(s) = 1.96 TeV

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    We present the results of a search for associated production of the chargino and neutralino supersymmetric particles using up to 1.1 fb-1 of integrated luminosity collected by the CDF II experiment at the Tevatron ppbar collider at a center-of-mass energy of 1.96 TeV. The search is conducted by analyzing events with a large transverse momentum imbalance and either three charged leptons or two charged leptons of the same electric charge. The numbers of observed events are found to be consistent with standard model expectations. Upper limits on the production cross section are derived in different theoretical models. In one of these models a lower limit on the mass of the chargino is set at 129 GeV/c^2 at the 95% confidence level.Comment: To be submitted to Phys.Rev.Let

    Measurement of the W+W- Production Cross Section in ppbar Collisions at sqrt(s)=1.96 TeV using Dilepton Events

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    We present a measurement of the W+W- production cross section using 184/pb of ppbar collisions at a center-of-mass energy of 1.96 TeV collected with the Collider Detector at Fermilab. Using the dilepton decay channel W+W- -> l+l-vvbar, where the charged leptons can be either electrons or muons, we find 17 candidate events compared to an expected background of 5.0+2.2-0.8 events. The resulting W+W- production cross section measurement of sigma(ppbar -> W+W-) = 14.6 +5.8 -5.1 (stat) +1.8 -3.0 (syst) +-0.9 (lum) pb agrees well with the Standard Model expectation.Comment: 8 pages, 2 figures, 2 tables. To be submitted to Physical Review Letter

    Search for gravitational waves from Scorpius X-1 in the second Advanced LIGO observing run with an improved hidden Markov model

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    We present results from a semicoherent search for continuous gravitational waves from the low-mass x-ray binary Scorpius X-1, using a hidden Markov model (HMM) to track spin wandering. This search improves on previous HMM-based searches of LIGO data by using an improved frequency domain matched filter, the J-statistic, and by analyzing data from Advanced LIGO's second observing run. In the frequency range searched, from 60 to 650 Hz, we find no evidence of gravitational radiation. At 194.6 Hz, the most sensitive search frequency, we report an upper limit on gravitational wave strain (at 95% confidence) of h095%=3.47×10-25 when marginalizing over source inclination angle. This is the most sensitive search for Scorpius X-1, to date, that is specifically designed to be robust in the presence of spin wandering. © 2019 American Physical Society

    Search for Tensor, Vector, and Scalar Polarizations in the Stochastic Gravitational-Wave Background

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    The detection of gravitational waves with Advanced LIGO and Advanced Virgo has enabled novel tests of general relativity, including direct study of the polarization of gravitational waves. While general relativity allows for only two tensor gravitational-wave polarizations, general metric theories can additionally predict two vector and two scalar polarizations. The polarization of gravitational waves is encoded in the spectral shape of the stochastic gravitational-wave background, formed by the superposition of cosmological and individually unresolved astrophysical sources. Using data recorded by Advanced LIGO during its first observing run, we search for a stochastic background of generically polarized gravitational waves. We find no evidence for a background of any polarization, and place the first direct bounds on the contributions of vector and scalar polarizations to the stochastic background. Under log-uniform priors for the energy in each polarization, we limit the energy densities of tensor, vector, and scalar modes at 95% credibility to Ω0T<5.58×10-8, Ω0V<6.35×10-8, and Ω0S<1.08×10-7 at a reference frequency f0=25 Hz. © 2018 American Physical Society

    Erratum: "A Gravitational-wave Measurement of the Hubble Constant Following the Second Observing Run of Advanced LIGO and Virgo" (2021, ApJ, 909, 218)

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