6 research outputs found

    Existence and Construction of LCD codes over Finite Fields

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    We demonstrate the existence of Euclidean and Hermitian LCD codes over finite fields with various parameters. In addition, we provide a method for constructing multiple Hermitian LCD (self orthogonal, self dual) codes from a given Hermitian LCD (self orthogonal, self dual) code, as well as a method for constructing Euclidean (Hermitian) LCD codes with parameters [n+1,k+1][n+1, k+1] and [n,k+1][n,k+1] from a given Euclidean (Hermitian) LCD code with parameters [n,k][n,k] over finite fields. Finally, we provide some findings on σ\sigma-LCD codes over finite fields

    Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial

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    Background Post-partum haemorrhage is the leading cause of maternal death worldwide. Early administration of tranexamic acid reduces deaths due to bleeding in trauma patients. We aimed to assess the effects of early administration of tranexamic acid on death, hysterectomy, and other relevant outcomes in women with post-partum haemorrhage. Methods In this randomised, double-blind, placebo-controlled trial, we recruited women aged 16 years and older with a clinical diagnosis of post-partum haemorrhage after a vaginal birth or caesarean section from 193 hospitals in 21 countries. We randomly assigned women to receive either 1 g intravenous tranexamic acid or matching placebo in addition to usual care. If bleeding continued after 30 min, or stopped and restarted within 24 h of the first dose, a second dose of 1 g of tranexamic acid or placebo could be given. Patients were assigned by selection of a numbered treatment pack from a box containing eight numbered packs that were identical apart from the pack number. Participants, care givers, and those assessing outcomes were masked to allocation. We originally planned to enrol 15 000 women with a composite primary endpoint of death from all-causes or hysterectomy within 42 days of giving birth. However, during the trial it became apparent that the decision to conduct a hysterectomy was often made at the same time as randomisation. Although tranexamic acid could influence the risk of death in these cases, it could not affect the risk of hysterectomy. We therefore increased the sample size from 15 000 to 20 000 women in order to estimate the effect of tranexamic acid on the risk of death from post-partum haemorrhage. All analyses were done on an intention-to-treat basis. This trial is registered with ISRCTN76912190 (Dec 8, 2008); ClinicalTrials.gov, number NCT00872469; and PACTR201007000192283. Findings Between March, 2010, and April, 2016, 20 060 women were enrolled and randomly assigned to receive tranexamic acid (n=10 051) or placebo (n=10 009), of whom 10 036 and 9985, respectively, were included in the analysis. Death due to bleeding was significantly reduced in women given tranexamic acid (155 [1·5%] of 10 036 patients vs 191 [1·9%] of 9985 in the placebo group, risk ratio [RR] 0·81, 95% CI 0·65–1·00; p=0·045), especially in women given treatment within 3 h of giving birth (89 [1·2%] in the tranexamic acid group vs 127 [1·7%] in the placebo group, RR 0·69, 95% CI 0·52–0·91; p=0·008). All other causes of death did not differ significantly by group. Hysterectomy was not reduced with tranexamic acid (358 [3·6%] patients in the tranexamic acid group vs 351 [3·5%] in the placebo group, RR 1·02, 95% CI 0·88–1·07; p=0·84). The composite primary endpoint of death from all causes or hysterectomy was not reduced with tranexamic acid (534 [5·3%] deaths or hysterectomies in the tranexamic acid group vs 546 [5·5%] in the placebo group, RR 0·97, 95% CI 0·87-1·09; p=0·65). Adverse events (including thromboembolic events) did not differ significantly in the tranexamic acid versus placebo group. Interpretation Tranexamic acid reduces death due to bleeding in women with post-partum haemorrhage with no adverse effects. When used as a treatment for postpartum haemorrhage, tranexamic acid should be given as soon as possible after bleeding onset. Funding London School of Hygiene & Tropical Medicine, Pfizer, UK Department of Health, Wellcome Trust, and Bill & Melinda Gates Foundation

    Atrial Myxoma-Related to Chronic Immunosuppression: A case report

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    AbstractAlthough rare, atrial myxoma is the most common primary tumour of the heart. Its relation to immunosuppression in solid organ transplant is presently debateable. We report the case of a 71-year-old male patient who underwent renal transplant 17years prior. Since that time he continued high dose immunosuppression without physician consultation and presented to us with atrial myxoma and its complications raising the question of any association between immunosuppression and the development of atrial myxoma

    A comprehensive review of photovoltaic-thermal (PVT) technology: Performance evaluation and contemporary development

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    The unceasing deterioration of the environment and the sharp rise in the price of conventional sources of energy led scientists to search for more resilient and long-lasting energy sources. As one of the numerous forms of renewable energy sources available, solar energy is the most cost-effective, clean, free, and environmentally friendly alternative. Photovoltaic and thermal (PVT) energy systems are becoming increasingly popular as they maximise the benefits of solar radiation, which generates electricity and heat at the same time. This paper elaborates on various aspects of PVT systems including the concept, material, and methods of review, classifications of PVT systems, air-type, water-type, PVT with nano-fluid applying a range of methodologies, and building-integrated PVT (BIPVT) systems. Based on existing literature, PVT systems are also compared in terms of performance parameters and improved efficiency. From the findings of various studies, an unglazed air collector is found to be better for improving thermal efficiency, also this PVT system is technically cheaper in terms of accounting. This study suggests that to decrease the cost and enhance the effectiveness of such systems further research is needed

    Guidelines for diagnostic flexible bronchoscopy in adults: Joint Indian Chest Society/National College of chest physicians (I)/Indian association for bronchology recommendations

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