Micro-scale surface-patterning influences biofilm formation

The formation of biofilms on indwelling/implanted medical devices is a common problem. One of the approaches used to prevent biofilm formation on medical devices is to inhibit bacterial attachment by modification of the synthetic polymers used to fabricate the device. In this work, we assessed how micro-scale features (patterns) imprinted onto the surface of silicone elastomer similar to that used for medical applications influenced biofilm formation by Staphylococcus aureus , Staphylococcus epidermidis , and Pseudomonas aeruginosa . Patterns were transferred from a multi-patterned oxidized silicon-wafer master-template to silicone elastomer. Features consisted of bars, squares, and circles each extending 0.51 \ub5m above the surface. Feature sizes ranged between 1.78 and 22.25 \ub5m. Distances separating features ranged between 0.26 and 17.35 \ub5m. Bacterial biofilm formation on discs cut from imprinted silicone elastomer was assessed by direct microscopic observation and quantified as the surface area covered by biofilm. Unpatterned silicone elastomer served as a control. Several of the micro-scale patterns imprinted into the silicone elastomer significantly reduced biofilm formation by each bacterium and interrupted biofilm continuity. Although there were differences in detail among strains, bacteria tended to attach in the area between features more than to the surface of the feature itself

N=31, D=11

We show that eleven-dimensional supergravity backgrounds with thirty one supersymmetries, N=31, admit an additional Killing spinor and so they are locally isometric to maximally supersymmetric ones. This rules out the existence of simply connected eleven-dimensional supergravity preons. We also show that N=15 solutions of type I supergravities are locally isometric to Minkowski spacetime.Comment: 17 page

On a class of 4D Kahler bases and AdS_5 supersymmetric Black Holes

We construct a class of toric Kahler manifolds, M_4, of real dimension four, a subset of which corresponds to the Kahler bases of all known 5D asymptotically AdS_5 supersymmetric black-holes. In a certain limit, these Kahler spaces take the form of cones over Sasaki spaces, which, in turn, are fibrations over toric manifolds of real dimension two. The metric on M_4 is completely determined by a single function H(x), which is the conformal factor of the two dimensional space. We study the solutions of minimal five dimensional gauged supergravity having this class of Kahler spaces as base and show that in order to generate a five dimensional solution H(x) must obey a simple sixth order differential equation. We discuss the solutions in detail, which include all known asymptotically AdS_5 black holes as well as other spacetimes with non-compact horizons. Moreover we find an infinite number of supersymmetric deformations of these spacetimes with less spatial isometries than the base space. These deformations vanish at the horizon, but become relevant asymptotically.Comment: 34 pages, 3 figures. v2: formula (8.35) and other minor typos corrected; references added; accepted for publication in JHE

Predicting Student Failure in an Introductory Programming Course with Multiple Back-Propagation

One of the most challenging tasks in computer science and similar courses consists of both teaching and learning computer programming. Usually this requires a great deal of work, dedication, and motivation from both teachers and students. Accordingly, ever since the first programming languages emerged, the problems inherent to programming teaching and learning have been studied and investigated. The theme is very serious, not only for the important concepts underlying computer science courses but also for reducing the lack of motivation, failure, and abandonment that result from students frustration. Therefore, early identification of potential problems and immediate response is a fundamental aspect to avoid student’s failure and reduce dropout rates. In this paper, we propose a machine-learning (neural network) predictive model of student failure based on the student profile, which is built throughout programming classes by continuously monitoring and evaluating student activities. The resulting model allows teachers to early identify students that are more likely to fail, allowing them to devote more time to those students and try novel strategies to improve their programming skills

All timelike supersymmetric solutions of N=2, D=4 gauged supergravity coupled to abelian vector multiplets

The timelike supersymmetric solutions of N=2, D=4 gauged supergravity coupled to an arbitrary number of abelian vector multiplets are classified using spinorial geometry techniques. We show that the generalized holonomy group for vacua preserving N supersymmetries is GL((8-N)/2,C) $\ltimes$ N/2 C^((8-N)/2) $\subseteq$ GL(8,R), where N=0,2,4,6,8. The spacetime turns out to be a fibration over a three-dimensional base manifold with U(1) holonomy and nontrivial torsion. Our results can be used to construct new supersymmetric AdS black holes with nontrivial scalar fields turned on.Comment: 35 pages, uses JHEP3.cl

Quantum random walks in optical lattices

We propose an experimental realization of discrete quantum random walks using neutral atoms trapped in optical lattices. The random walk is taking place in position space and experimental implementation with present day technology --even using existing set-ups-- seems feasible. We analyze the influence of possible imperfections in the experiment and investigate the transition from a quantum random walk to the classical random walk for increasing errors and decoherence.Comment: 8 pages, 4 figure

Fast Non-Adiabatic Two Qubit Gates for the Kane Quantum Computer

In this paper we apply the canonical decomposition of two qubit unitaries to find pulse schemes to control the proposed Kane quantum computer. We explicitly find pulse sequences for the CNOT, swap, square root of swap and controlled Z rotations. We analyze the speed and fidelity of these gates, both of which compare favorably to existing schemes. The pulse sequences presented in this paper are theoretically faster, higher fidelity, and simpler than existing schemes. Any two qubit gate may be easily found and implemented using similar pulse sequences. Numerical simulation is used to verify the accuracy of each pulse scheme

Quantum computing with mixed states

We discuss a model for quantum computing with initially mixed states. Although such a computer is known to be less powerful than a quantum computer operating with pure (entangled) states, it may efficiently solve some problems for which no efficient classical algorithms are known. We suggest a new implementation of quantum computation with initially mixed states in which an algorithm realization is achieved by means of optimal basis independent transformations of qubits.Comment: 2 figures, 52 reference

Theory of Decoherence-Free Fault-Tolerant Universal Quantum Computation

Universal quantum computation on decoherence-free subspaces and subsystems (DFSs) is examined with particular emphasis on using only physically relevant interactions. A necessary and sufficient condition for the existence of decoherence-free (noiseless) subsystems in the Markovian regime is derived here for the first time. A stabilizer formalism for DFSs is then developed which allows for the explicit understanding of these in their dual role as quantum error correcting codes. Conditions for the existence of Hamiltonians whose induced evolution always preserves a DFS are derived within this stabilizer formalism. Two possible collective decoherence mechanisms arising from permutation symmetries of the system-bath coupling are examined within this framework. It is shown that in both cases universal quantum computation which always preserves the DFS (*natural fault-tolerant computation*) can be performed using only two-body interactions. This is in marked contrast to standard error correcting codes, where all known constructions using one or two-body interactions must leave the codespace during the on-time of the fault-tolerant gates. A further consequence of our universality construction is that a single exchange Hamiltonian can be used to perform universal quantum computation on an encoded space whose asymptotic coding efficiency is unity. The exchange Hamiltonian, which is naturally present in many quantum systems, is thus *asymptotically universal*.Comment: 40 pages (body: 30, appendices: 3, figures: 5, references: 2). Fixed problem with non-printing figures. New references added, minor typos correcte

A First Search for coincident Gravitational Waves and High Energy Neutrinos using LIGO, Virgo and ANTARES data from 2007

We present the results of the first search for gravitational wave bursts associated with high energy neutrinos. Together, these messengers could reveal new, hidden sources that are not observed by conventional photon astronomy, particularly at high energy. Our search uses neutrinos detected by the underwater neutrino telescope ANTARES in its 5 line configuration during the period January - September 2007, which coincided with the fifth and first science runs of LIGO and Virgo, respectively. The LIGO-Virgo data were analysed for candidate gravitational-wave signals coincident in time and direction with the neutrino events. No significant coincident events were observed. We place limits on the density of joint high energy neutrino - gravitational wave emission events in the local universe, and compare them with densities of merger and core-collapse events.Comment: 19 pages, 8 figures, science summary page at http://www.ligo.org/science/Publication-S5LV_ANTARES/index.php. Public access area to figures, tables at https://dcc.ligo.org/cgi-bin/DocDB/ShowDocument?docid=p120000