404 research outputs found
Inventory Policy for Dependent Demand Where Parent Demand Has Decreasing Pattern
When a product reaches its maturity in its life cycle, some innovations have to be put in that product in order to lengthen its life cycle. Otherwise, that product will be perceived as obsolete. It might affect the demand of that product i.e. the demand become decreasing. Based on the observation that we conducted over two smart phone brands, the phenomena that the demand has declining pattern really happened in the real situation. In addition, the observation shows that the product life cycle is getting shorter. This implies that the manufacturer has to deal with decreasing demand more often. A case study is presented in this paper, in which manufacturer experienced final product with decreasing demand pattern. Some lot sizing techniques, such as Lot for Lot, Silver Meal 1, Silver Meal 2, Least Unit Cost, Part Period Balancing, and Incremental, are tested to solve the inventory policy for both final product (parent) and its components (child). It is concluded that a company should not consider only one component or one level whenever deciding the inventory policy, i.e. production lot size. It is shown by the case study that the best lot sizing technique for a particular parent of product whenever the company only consider the parent is different with the best lot sizing technique whenever the company consider the parent and its child. For the case presented, it is shown that the smallest total cost of parent and child is most likely occurred whenever Silver Meal 2 lot sizing technique is applied in the parent with decreasing demand pattern.
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness
BACKGROUND:
There are conflicting data on the effects of antipsychotic medications on delirium in patients in the intensive care unit (ICU).
METHODS:
In a randomized, double-blind, placebo-controlled trial, we assigned patients with acute respiratory failure or shock and hypoactive or hyperactive delirium to receive intravenous boluses of haloperidol (maximum dose, 20 mg daily), ziprasidone (maximum dose, 40 mg daily), or placebo. The volume and dose of a trial drug or placebo was halved or doubled at 12-hour intervals on the basis of the presence or absence of delirium, as detected with the use of the Confusion Assessment Method for the ICU, and of side effects of the intervention. The primary end point was the number of days alive without delirium or coma during the 14-day intervention period. Secondary end points included 30-day and 90-day survival, time to freedom from mechanical ventilation, and time to ICU and hospital discharge. Safety end points included extrapyramidal symptoms and excessive sedation.
RESULTS:
Written informed consent was obtained from 1183 patients or their authorized representatives. Delirium developed in 566 patients (48%), of whom 89% had hypoactive delirium and 11% had hyperactive delirium. Of the 566 patients, 184 were randomly assigned to receive placebo, 192 to receive haloperidol, and 190 to receive ziprasidone. The median duration of exposure to a trial drug or placebo was 4 days (interquartile range, 3 to 7). The median number of days alive without delirium or coma was 8.5 (95% confidence interval [CI], 5.6 to 9.9) in the placebo group, 7.9 (95% CI, 4.4 to 9.6) in the haloperidol group, and 8.7 (95% CI, 5.9 to 10.0) in the ziprasidone group (P=0.26 for overall effect across trial groups). The use of haloperidol or ziprasidone, as compared with placebo, had no significant effect on the primary end point (odds ratios, 0.88 [95% CI, 0.64 to 1.21] and 1.04 [95% CI, 0.73 to 1.48], respectively). There were no significant between-group differences with respect to the secondary end points or the frequency of extrapyramidal symptoms.
CONCLUSIONS:
The use of haloperidol or ziprasidone, as compared with placebo, in patients with acute respiratory failure or shock and hypoactive or hyperactive delirium in the ICU did not significantly alter the duration of delirium. (Funded by the National Institutes of Health and the VA Geriatric Research Education and Clinical Center; MIND-USA ClinicalTrials.gov number, NCT01211522 .)
Magnetic and quantum entanglement properties of the distorted diamond chain model for azurite
We present the results of magnetic properties and entanglement of the
distorted diamond chain model for azurite using pure quantum exchange
interactions. The magnetic properties and concurrence as a measure of pairwise
thermal entanglement have been studied by means of variational mean-field like
treatment based on Gibbs-Bogoliubov inequality. Such a system can be considered
as an approximation of the natural material azurite, Cu3(CO3)2(OH)2. For values
of exchange parameters, which are taken from experimental results, we study the
thermodynamic properties, such as azurite specific heat and magnetic
susceptibility. We also have studied the thermal entanglement properties and
magnetization plateau of the distorted diamond chain model for azurite
Corrections to Hawking-like Radiation for a Friedmann-Robertson-Walker Universe
Recently, a Hamilton-Jacobi method beyond semiclassical approximation in
black hole physics was developed by \emph{Banerjee} and
\emph{Majhi}\cite{beyond0}. In this paper, we generalize their analysis of
black holes to the case of Friedmann-Robertson-Walker (FRW) universe. It is
shown that all the higher order quantum corrections in the single particle
action are proportional to the usual semiclassical contribution. The
corrections to the Hawking-like temperature and entropy of apparent horizon for
FRW universe are also obtained. In the corrected entropy, the area law involves
logarithmic area correction together with the standard inverse power of area
term.Comment: 10 pages, no figures, comments are welcome; v2: references added and
some typoes corrected, to appear in Euro.Phys.J.C; v3:a defect corrected. We
thank Dr.Elias Vagenas for pointing out a defect of our pape
ASTEC -- the Aarhus STellar Evolution Code
The Aarhus code is the result of a long development, starting in 1974, and
still ongoing. A novel feature is the integration of the computation of
adiabatic oscillations for specified models as part of the code. It offers
substantial flexibility in terms of microphysics and has been carefully tested
for the computation of solar models. However, considerable development is still
required in the treatment of nuclear reactions, diffusion and convective
mixing.Comment: Astrophys. Space Sci, in the pres
Does accelerating universe indicates Brans-Dicke theory
The evolution of universe in Brans-Dicke (BD) theory is discussed in this
paper.
Considering a parameterized scenario for BD scalar field
which plays the role of gravitational "constant" ,
we apply the Markov Chain Monte Carlo method to investigate a global
constraints on BD theory with a self-interacting potential according to the
current observational data: Union2 dataset of type supernovae Ia (SNIa),
high-redshift Gamma-Ray Bursts (GRBs) data, observational Hubble data (OHD),
the cluster X-ray gas mass fraction, the baryon acoustic oscillation (BAO), and
the cosmic microwave background (CMB) data. It is shown that an expanded
universe from deceleration to acceleration is given in this theory, and the
constraint results of dimensionless matter density and parameter
are, and
which is consistent with the
result of current experiment exploration, . In
addition, we use the geometrical diagnostic method, jerk parameter , to
distinguish the BD theory and cosmological constant model in Einstein's theory
of general relativity.Comment: 16 pages, 3 figure
Heavy quarkonium: progress, puzzles, and opportunities
A golden age for heavy quarkonium physics dawned a decade ago, initiated by
the confluence of exciting advances in quantum chromodynamics (QCD) and an
explosion of related experimental activity. The early years of this period were
chronicled in the Quarkonium Working Group (QWG) CERN Yellow Report (YR) in
2004, which presented a comprehensive review of the status of the field at that
time and provided specific recommendations for further progress. However, the
broad spectrum of subsequent breakthroughs, surprises, and continuing puzzles
could only be partially anticipated. Since the release of the YR, the BESII
program concluded only to give birth to BESIII; the -factories and CLEO-c
flourished; quarkonium production and polarization measurements at HERA and the
Tevatron matured; and heavy-ion collisions at RHIC have opened a window on the
deconfinement regime. All these experiments leave legacies of quality,
precision, and unsolved mysteries for quarkonium physics, and therefore beg for
continuing investigations. The plethora of newly-found quarkonium-like states
unleashed a flood of theoretical investigations into new forms of matter such
as quark-gluon hybrids, mesonic molecules, and tetraquarks. Measurements of the
spectroscopy, decays, production, and in-medium behavior of c\bar{c}, b\bar{b},
and b\bar{c} bound states have been shown to validate some theoretical
approaches to QCD and highlight lack of quantitative success for others. The
intriguing details of quarkonium suppression in heavy-ion collisions that have
emerged from RHIC have elevated the importance of separating hot- and
cold-nuclear-matter effects in quark-gluon plasma studies. This review
systematically addresses all these matters and concludes by prioritizing
directions for ongoing and future efforts.Comment: 182 pages, 112 figures. Editors: N. Brambilla, S. Eidelman, B. K.
Heltsley, R. Vogt. Section Coordinators: G. T. Bodwin, E. Eichten, A. D.
Frawley, A. B. Meyer, R. E. Mitchell, V. Papadimitriou, P. Petreczky, A. A.
Petrov, P. Robbe, A. Vair
Study of Inclusive Strange-Baryon Production and Search for Pentaquarks in Two-Photon Collisions at LEP
Measurements of inclusive production of the Lambda, Xi- and Xi*(1530) baryons
in two-photon collisions with the L3 detector at LEP are presented. The
inclusive differential cross sections for Lambda and Xi- are measured as a
function of the baryon transverse momentum, pt, and pseudo-rapidity, eta. The
mean number of Lambda, Xi- and Xi*(1530) baryons per hadronic two-photon event
is determined in the kinematic range 0.4 GeV < pt< 2.5 GeV, |eta| < 1.2.
Overall agreement with the theoretical models and Monte Carlo predictions is
observed. A search for inclusive production of the pentaquark theta+(1540) in
two-photon collisions through the decay theta+ -> proton K0s is also presented.
No evidence for production of this state is found
Measurement of the polarisation of W bosons produced with large transverse momentum in pp collisions at sqrt(s) = 7 TeV with the ATLAS experiment
This paper describes an analysis of the angular distribution of W->enu and
W->munu decays, using data from pp collisions at sqrt(s) = 7 TeV recorded with
the ATLAS detector at the LHC in 2010, corresponding to an integrated
luminosity of about 35 pb^-1. Using the decay lepton transverse momentum and
the missing transverse energy, the W decay angular distribution projected onto
the transverse plane is obtained and analysed in terms of helicity fractions
f0, fL and fR over two ranges of W transverse momentum (ptw): 35 < ptw < 50 GeV
and ptw > 50 GeV. Good agreement is found with theoretical predictions. For ptw
> 50 GeV, the values of f0 and fL-fR, averaged over charge and lepton flavour,
are measured to be : f0 = 0.127 +/- 0.030 +/- 0.108 and fL-fR = 0.252 +/- 0.017
+/- 0.030, where the first uncertainties are statistical, and the second
include all systematic effects.Comment: 19 pages plus author list (34 pages total), 9 figures, 11 tables,
revised author list, matches European Journal of Physics C versio
Observation of a new chi_b state in radiative transitions to Upsilon(1S) and Upsilon(2S) at ATLAS
The chi_b(nP) quarkonium states are produced in proton-proton collisions at
the Large Hadron Collider (LHC) at sqrt(s) = 7 TeV and recorded by the ATLAS
detector. Using a data sample corresponding to an integrated luminosity of 4.4
fb^-1, these states are reconstructed through their radiative decays to
Upsilon(1S,2S) with Upsilon->mu+mu-. In addition to the mass peaks
corresponding to the decay modes chi_b(1P,2P)->Upsilon(1S)gamma, a new
structure centered at a mass of 10.530+/-0.005 (stat.)+/-0.009 (syst.) GeV is
also observed, in both the Upsilon(1S)gamma and Upsilon(2S)gamma decay modes.
This is interpreted as the chi_b(3P) system.Comment: 5 pages plus author list (18 pages total), 2 figures, 1 table,
corrected author list, matches final version in Physical Review Letter
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