Crystallographic texture evolution in Ti–35Nb alloy deformed by cold rolling

This work presents the results of a microstructural characterization of the Ti–35Nb alloy deformed by cold rolling. Initially, samples of the Ti–35Nb (wt%) alloy were obtained by electric arc melting. After melting, these samples were solution heat-treated at 1000 °C for 8 h and water quenched. The resulting microstructure was composed of β-phase (bcc) combined with orthorhombic martensite (α″). Samples were cold-rolled in multiple passes to reduce their thickness by up to 85% without intermediary annealing. They were then characterized by light optical microscopy, X-ray diffraction and Vickers hardness measurements. Young’s modulus was determined by ultrasonic methods and nanoindentation measurements. The texture evolution and orientation relationship between phases were studied by X-ray diffraction and electron backscatter diffraction (EBSD). The results reveal the presence of shear bands in the deformed samples, an orientation of the orthorhombic martensite phase in relation to the rolling direction, and variations of Young’s modulus in response to deformation. The textural results of the β-phase show a typical bcc rolling texture with strong (1 1 0) fiber and weak (1 1 1) fiber. The intensity of the (1 1 0) fiber increases with deformation60653660CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPNão temNão temNão temThe authors gratefully acknowledge the Brazilian research funding agencies FAPESP (State of São Paulo Research Foundation), CNPq (National Council for Scientific and Technological Development) and CAPES (Federal Agency for the support and Evaluation of Graduate Education) for their financial support of this wor

Relato de Pesquisa: Projeto Ciência e Performance, estudo da Conferência Internacional sobre Comunicação Pública da Ciência e Tecnologia

 O presente artigo está relacionado ao Projeto de Pesquisa “Ciência e Performance: estudo da Conferência Internacional sobre Comunicação Pública da Ciência e Tecnologia”. Apresentamos aqui os resultados parciais de um questionário disponibilizado no dia 13 de maio de 2014, logo após a Conferência na Bahia-Brasil, numa lista de discussão da Network for the Public Communication of Science and Technology (PCST). O questionário obteve 42 respostas de pesquisadores de diferentes países, com predominância do Brasil, Índia, Estados Unidos e Itália, seguidos da Austrália e da Inglaterra. INFORME DE INVESTI GACION : PROYE CTO DE INVESTI GACIÓN “CIEN CIA Y PERFOR MAN CE: ESTU DIO DE LA CONFEREN CIA INTERNA CIO NAL SOBRE COMUNI CACIÓN PÚBLI CA DE LA CIEN CIA Y LA TE CNO LO GÍA ”Resumen: El presente artículo está relacionado con el Proyecto de Investigación “Ciencia y Performance: estudio de la Conferencia Internacional sobre Comunicación Pública de la Ciencia y la Tecnología”. Presentamos aquí los resultados parciales de una encuesta realizada en el día 13 de mayo de 2014, poco después de la Conferencia en Bahía-Brasil, en una lista de discusión de la Network for the Public Communication of Science and Technology (PCST). El cuestionario obtuvo 42 respuestas de investigadores de diferentes países, con predominio de Brasil, India, Estados Unidos e Italia, seguidos de Australia e InglaterraRESEARCH RE PORT : RESEAR CH PRO JECT “SCIEN CE AN D PERFOR MAN CE: STU DY OF INTERNATIONAL INTERNATIONAL PUBLI C COMMUNI CATION ATION OF SCIEN CE AN D TE CHNOLO GY CONFEREN CE”ABSTRACT: The present work is a report Concerning the Research Project “Science and Performance: Study of International Public Communication of Science and Technology Conference”. We present here the partial results of a questionnaire made available on May 13, 2014, shortly after the Conference in Bahia, Brazil, in a mailing list of the Network for the Public Communication of Science and Technology. The survey received 42 responses from researchers of different countries, especially Brazil, India, United States and Italy, followed by Australia and England

El análisis de calidad de semillas en un nuevo escenario tecnológico

La evaluación de calidad de semillas es fundamental para conocer el potencial fisiológico de un lote y disponer de semillas de calidad en cada campaña agrícola. La calidad determina el éxito en la implantación del cultivo y el potencial productivo a campo.EEA OliverosFil: Martinez, Mailen Ariela. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Oliveros; ArgentinaFil: Martinez, Mailen Ariela. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Martinez, Mailen Ariela. Universidad Nacional de Rosario. Facultad de Ciencias Agrarias. Departamento de Fisiología Vegetal; ArgentinaFil: Gomes Junior, F.G. Universidade de Sao Pablo. ESALQ. Departamento de Produção Vegetal; BrasilFil: Arango, Miriam Raquel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Oliveros; ArgentinaFil: Gallo, Carina Del Valle. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Oliveros; Argentin

Epidermal growth factor receptor regulates fibrinolytic pathway elements in cervical cancer: functional and prognostic implications

Epidermal growth factor receptor (EGFR) signaling and components of the fibrinolytic system, including urokinase-type plasminogen activator (uPA) and thrombomodulin (TM), have been implicated in tumor progression. In the present study, we employed cBioPortal platform (http://www.cbioportal.org/), cancer cell lines, and an in vivo model of immunocompromised mice to evaluate a possible cooperation between EGFR signaling, uPA, and TM expression/function in the context of cervical cancer. cBioPortal analysis revealed that EGFR, uPA, and TM are positively correlated in tumor samples of cervical cancer patients, showing a negative prognostic impact. Aggressive human cervical cancer cells (CASKI) presented higher gene expression levels of EGFR, uPA, and TM compared to its less aggressive counterpart (C-33A cells). EGFR induces uPA expression in CASKI cells through both PI3K-Akt and MEK1/2-ERK1/2 downstream effectors, whereas TM expression induced by EGFR was dependent on PI3K/Akt signaling alone. uPA induced cell-morphology modifications and cell migration in an EGFR-dependent and -independent manner, respectively. Finally, treatment with cetuximab reduced in vivo CASKI xenografted-tumor growth in nude mice, and decreased intratumoral uPA expression, while TM expression was unaltered. In conclusion, we showed that EGFR signaling regulated expression of the fibrinolytic system component uPA in both in vitro and in vivo settings, while uPA also participated in cell-morphology modifications and migration in a human cervical cancer model

Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector

A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results