Evaluation of Serum PSA in Different Storage Environments

ABSTRACT Background and Objective: Prostate cancer is a prevalent disease around the world. Th

Olive polyphenols and the metabolic syndrome

Here, the effects of consuming polyphenol-rich olive products, including olive leaves, their crude extract, and extra virgin olive oil, on aspects of the metabolic syndrome are reviewed. We have sought to summarize the available scientific evidence from dietary intervention trials demonstrating a role for these phytochemicals in ameliorating aberrant glucose metabolism, high blood pressure and elevated blood lipids, and we discuss the potential mechanisms underpinning these observations. Searches for relevant literature published in English were conducted via PubMed and Science Direct. Based on published dietary intervention studies, there is convincing evidence to show that olive polyphenols, independently of olive lipids, reduce risk factors for metabolic syndrome, in particular by improving blood sugar and blood pressure control, and in reducing low density lipoprotein oxidation. There is more limited evidence to suggest that the consumption of olive polyphenols or related products can reduce body weight and visceral fat or impede weight gain, and similarly there are some limited data suggesting improved lipid profiles. There is some mechanistic data to support observations made in human volunteers, but further work is needed in this area. The consumption of olive polyphenols within the context of a healthy pattern of food intake may, in part, explain the reduced risk of metabolic disease associated with adherence to the Mediterranean diet

Update of the Scientific Opinion on opium alkaloids in poppy seeds

The CONTAM Panel wishes to thank the hearing experts: Pavel Cihlar, Daniel Doerge and Vaclav Lohr for the support provided to this scientific output. The CONTAM Panel acknowledges all European competent institutions and other stakeholders that provided occurrence data on opium alkaloids in food, and supported the data collection for the Comprehensive European Food Consumption Database. Adopted: 22 March 2018 Reproduction of the images listed below is prohibited and permission must be sought directly from the copyright holder:Figure A.1 in Appendix A: © Elsevier.Peer reviewedPublisher PD

Effect of Hypericum perforatum aqueous extracts on serum lipids, aminotransferases, and lipid peroxidation in hyperlipidemic rats

Background: Patients with high levels of total cholesterol (TCH), low-density lipoprotein cholesterol (LDL-CH), and triglyceride (TG) are at increased risk of coronary heart disease. Studies have shown that flavonoids and antioxidant compounds have beneficial effects on hyperlipidemia. Objectives: The aim of the present study was to evaluate the effects of extract of Hypericum perforatum (EHP) on the serum lipid profile (TCH, TG, and LDL-CH), aminotransferase, alkaline phosphatase, and lipid peroxidation in hyperlipidemic rats. Materials and Methods: Thirty-two male rats weighting 200 ± 10 g were randomly divided into four experimental groups: 1) control, 2) control + EHP, 3) hyperlipidemia, and 4) hyperlipidemia + EHP. The rats in the hyperlipidemic groups were fed a high-fat diet for 60 days, and EHP (300 mg/kg) was injected intraperitoneally for 2 weeks in the rats in the second and fourth groups. At the end of the experimental period, blood samples from each group were analyzed. Results: There was a significant reduction in LDL-CH in the control + EHP group and the hyperlipidemia + EHP group (P < 0.05). TCH was significantly reduced in the control + EHP group (P < 0.05). There were no significant changes in the levels of TG and HDL-CH. Malondialdehyde, aspartate aminotransferase, and alanine aminotransferase were significantly reduced in the hyperlipidemia + EHP group (P < 0.05), with no significant change in alkaline phosphatase. Conclusions: EHP was able to both reduce LDL-CH and to significantly decrease markers of oxidative stress and lipid peroxidation induced by hyperlipidemia. Therefore, this herb, as a new pharmacological component, could be used to reduce certain blood lipids, lipid peroxidation, and aminotransferase markers

Effect of Salvia officinalis L. on serum level of glucose, lipid profiles and tissue level of Malondialdehyde in diabetic rats

Background and Objective: Hyperlipidemia and dyslipidemia are the prevalent risk factors associated with diabetes and their attenuation in diabetic patients with medicinal plants has great significance. This study was done to evaluate the effect of Salvia officinalis (SO) administration on serum glucose, lipids and tissue level of malondialdehyde (MDA) in streptozotocin induced diabetic rats. Methods: In this experimental study, 32 adult male Wistar rats were allocated into four groups including: control, SO-treated control, diabetic, and SO-treated diabetic groups. For induction of diabetes, a single dose of streptozotocin (60 mg/kg, i.p.) was used. SO powder was mixed with standard rat chow. Serum glucose and triglyceride, total cholesterol, LDL and HDL levels were determined on the first day and at 3rd and 6th weeks after the intervention. Finally, liver level of MDA and protein were determined in liver homogenate. Results: At 6th week, serum glucose level was significantly higher in diabetic and SO-treated diabetic groups (P<0.001) in compare to controls. Oral consumption of SO did not significantly reduce serum glucose level. Serum triglyceride level significantly reduced in SO-treated diabetic group in compare to diabetic group (P<0.05). There was not significant difference between SO-treated diabetic and diabetic groups. Serum level of cholesterol, HDL, LDL and tissue MDA level in SO-treated diabetic group in compare to diabetic group. Conclusion: Chronic administration of Salvia officinalis reduces serum triglyceride level in diabetic rats, with no significant effect on glucose level and Malondialdehyde

WiFi (CSI and RSSI) Data of three Coarse-grained Dining Activities (filling an electric kettle with water and turning it on, stir-frying cubed potato, and taking several cans from the fridge and putting them on a cabinet) in an Authentic Kitchen

Device-free human activity recognition (HAR) methods are attracting considerable interest due to their privacy preservation and ease of use nature of them. The granularity of the activities that a device-free HAR method aims to recognize is an important characteristic of it. This study aims to investigate the effect of activity granularity on the performance of device-free HAR methods. For this purpose, first, we utilized an authentic kitchen with an ESP32 microcontroller as a WiFi transceiver and an iPhone 12 min as a WiFi receiver. Then, we asked one user to perform three coarse-grained dining activities (i.e., filling an electric kettle with water and turning it on, stir-frying cubed potatoes, and taking several cans from the fridge and putting them on a cabinet) in the kitchen and gathering the Channel State Information (CSI) and Received Signal Strength Indicator (RSSI) data.The dataset contains 31 files for different activities (filling an electric kettle with water and turning it on, stir-frying cubed potato, and taking several cans from the fridge and putting them on a cabinet)Each file contains a list of data entries.Each data entry contains the following parts:type (CSI_DATA) - role (AP)- mac (96:DC:5A:81:E5:46) - rssi (-59) - rate (11) - sig_mode (1) - mcs (4) - bandwidth (0) - smoothing (1) - not_sounding (1) - aggregation (0) - stbc (0) - fec_coding (0) - sgi (0) - noise_floor (-95) - ampdu_cnt (0) - channel (8) - secondary_channel (0) - local_timestamp (1718710) - ant (0) - sig_len (126) - rx_state (0) - real_time_set (0) - real_timestamp (2.45605) - len (256) - CSI_DATA (a list of numbers)CSI_DATA in each data entry contains 128 numbers (64 complex numbers), The middle 11th complex numbers (22 numbers) which are 0 and we called the null subcarrier. In addition, the first complex number (2 numbers) is not valid because they are "LO Leakage". So, we will have 128 – 24 = 104 numbers which are 52 complex numbers. These are our 52 subcarriers of CSI data.</p

Original Article

Abstract Background: Opioids can exert adverse effects on the body. Morphine, an opioid drug, reduces hormone levels and fertility, and causes sexual activity disorders. Tribulus terrestris (TT) is a traditional herbal medicine used to enhance sexual activities. This study investigates the possible role of TT on sex hormones and gonadotropins with the intent to show its usefulness in treating fertility disorders in opioid users