The Martian daytime convective boundary layer: Results from radio occultation measurements and a mesoscale model

We investigate the behavior of the Martian daytime convective boundary layer (CBL) through a combination of data analysis and modeling. This study relies on two subsets of Mars Express radio occultation (RO) measurements that sounded the atmosphere in north- ern spring of successive Mars years. Only the first year of observations has been examined previously (Hinson et al., 2008); the second year provides complementary spatial coverage and greatly increases the total number of observations. Analysis of the RO profiles yields basic characteristics of the CBL, such as its depth D and the average potential temperature of the mixed layer θm. We also combine RO retrievals of surface pressure with surface tem- peratures from infrared sounding to characterize the surface forcing, expressing the result as a potential temperature θs. These observations are at local times in early afternoon for θs and late afternoon for θm and D, when each parameter is near its diurnal maximum. We use measurements at mid-to-low latitudes, which sample a wide range of θs (227–294 K), to determine the response of the lower atmosphere to spatial variations in surface forcing. The depth of the CBL ranges from less than 3 km in the midlatitude topographic basins to more than 9 km above elevated terrain in the tropics. The dependence of θm on θs is linear, with a characteristic slope of about 0.7 in both years. We gain further insight by performing a simulation with the Oregon State University Mars Mesoscale Model in a region centered on Isidis Planitia, which includes two potential landing sites for the Mars 2020 Rover. As expected from previous modeling of much smaller craters, the arc of steep to- pography along the western and southern margins of Isidis produces a distinctive, diurnally varying, mesoscale circulation. The simulation captures key features of the observations, such as the wide variations in θm and D — by 34 K and 9 km, respectively — that occur within this region. The model also accounts for peculiar features of RO profiles on the rim of Isidis, where the wind field strongly influences the depth and diurnal evolution of the CBL. Detailed comparisons with the observations validate the general performance of the model and confirm several aspects of the simulated wind field

STRAIN DIFFERENCES IN THE EXPRESSION OF THE EPA-1-RESTRICTING ELEMENT

Epa-1-specific cytotoxic T lymphocytes (CTL) lyse epidermal cells (EC) of different Epa-1 + H-2 k strains, such as AKR, CBA, C58, and RF, at different levels. We used an H-2K k -specific monoclonal antibody (mAb) to test the hypothesis that this phenomenon is due to differences in the H-2-restricting element. Initially, we established the specificity of this mAb for the Epa-1-restricting element by demonstrating its capacity to inhibit the lysis of CBA EC by Epa-1-specific CTL. We then used it as the probe in a cellular radioimmunoassay to quantify the expression of the restricting element by EC of different H-2 k strains. We found that C58 and RF EC bound significantly less of the mAb than did CBA EC. Although AKR also bound less of the mAb than did CBA EC, the difference was not statistically significant. To examine the generality of this phenomenon, we quantified the expression of K k antigens on spleen cells (SC) of the same four strains. We found that RF SC, but not AKR or C58 SC, bound significantly less of the K k mAb than did CBA SC. Thus, the differential CTL lysis of Epa-1 + EC of different strains probably reflects differences in expression of the H-2-restricting element rather than of the nominal antigen.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75485/1/j.1744-313X.1987.tb00375.x.pd

Scientific rationale for Uranus and Neptune <i>in situ</i> explorations

The ice giants Uranus and Neptune are the least understood class of planets in our solar system but the most frequently observed type of exoplanets. Presumed to have a small rocky core, a deep interior comprising ∼70% heavy elements surrounded by a more dilute outer envelope of H2 and He, Uranus and Neptune are fundamentally different from the better-explored gas giants Jupiter and Saturn. Because of the lack of dedicated exploration missions, our knowledge of the composition and atmospheric processes of these distant worlds is primarily derived from remote sensing from Earth-based observatories and space telescopes. As a result, Uranus's and Neptune's physical and atmospheric properties remain poorly constrained and their roles in the evolution of the Solar System not well understood. Exploration of an ice giant system is therefore a high-priority science objective as these systems (including the magnetosphere, satellites, rings, atmosphere, and interior) challenge our understanding of planetary formation and evolution. Here we describe the main scientific goals to be addressed by a future in situ exploration of an ice giant. An atmospheric entry probe targeting the 10-bar level, about 5 scale heights beneath the tropopause, would yield insight into two broad themes: i) the formation history of the ice giants and, in a broader extent, that of the Solar System, and ii) the processes at play in planetary atmospheres. The probe would descend under parachute to measure composition, structure, and dynamics, with data returned to Earth using a Carrier Relay Spacecraft as a relay station. In addition, possible mission concepts and partnerships are presented, and a strawman ice-giant probe payload is described. An ice-giant atmospheric probe could represent a significant ESA contribution to a future NASA ice-giant flagship mission

Exploring the justifications for selecting a drop landing task to assess injury biomechanics:A narrative review and analysis of landings performed by female netball players

When assessing biomechanics in a laboratory setting, task selection is critical to the production of accurate and meaningful data. The injury biomechanics of landing is commonly investigated in a laboratory setting using a drop landing task. However, why this task is so frequently chosen is unclear. Therefore, this narrative review aimed to (1) identify the justification/s provided within the published literature as to why a drop landing task was selected to investigate the injury biomechanics of landing in sport and (2) use current research evidence, supplemented by a new set of biomechanical data, to evaluate whether the justifications are supported. To achieve this, a comprehensive literature search using Scopus, PubMed, and SPORTDiscus online databases was conducted for studies that had collected biomechanical data relating to sport injuries using a drop landing task. In addition, kinematic and kinetic data were collected from female netball players during drop landings and maximum-effort countermovement jumps from the ground to grab a suspended ball. The literature search returned a total of 149 articles that were reviewed to determine the justification for selecting a drop landing task. Of these, 54% provided no explicit justification to explain why a drop landing task was chosen, and 15% stated it was selected because it had been used in previous research. Other reasons included that the drop landing provides high experimental control (16%), is a functional sports task (11%), and is a dynamic task (6%). Evidence in the literature suggests that the biomechanical data produced with drop landings may not be as externally valid as more sport-specific tasks. Biomechanical data showed that the drop landing may not control center of mass fall height any better than maximum-effort countermovement jumps from the ground. Further, the frequently used step-off technique to initiate drop landings resulted in kinematic and kinetic asymmetries between lower limbs, which would otherwise be symmetrical when performing a countermovement jump from the ground. Researchers should consider the limitations of a drop landing task and endeavor to improve the laboratory tasks used to collect biomechanical data to examine the injury biomechanics of landing.</p

Assessment of Intensive Care Unit Laboratory Values That Differ from Reference Ranges and Association with Patient Mortality and Length of Stay

10.1001/jamanetworkopen.2018.4521JAMA Network Open17e18452