59 research outputs found

    Measurement of the B0-anti-B0-Oscillation Frequency with Inclusive Dilepton Events

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    The B0B^0-Bˉ0\bar B^0 oscillation frequency has been measured with a sample of 23 million \B\bar B pairs collected with the BABAR detector at the PEP-II asymmetric B Factory at SLAC. In this sample, we select events in which both B mesons decay semileptonically and use the charge of the leptons to identify the flavor of each B meson. A simultaneous fit to the decay time difference distributions for opposite- and same-sign dilepton events gives Δmd=0.493±0.012(stat)±0.009(syst)\Delta m_d = 0.493 \pm 0.012{(stat)}\pm 0.009{(syst)} ps1^{-1}.Comment: 7 pages, 1 figure, submitted to Physical Review Letter

    The Physics of the B Factories

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    Copper-mediated formation of hydrogen peroxide from the amylin peptide:a novel mechanism for degeneration of islet cells in type-2 diabetes mellitus?

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    Amyloid deposits derived from the amylin peptide accumulate within pancreatic islet P-cells in most cases of type-2 diabetes mellitus (T2Dm). Human amylin 'oligomers' are toxic to these cells. Using two different experimental techniques, we found that H2O2 was generated during the aggregation of human amylin into amyloid fibrils. This process was greatly stimulated by Cu(II) ions, and human amylin was retained on a copper affinity column. In contrast, rodent amylin, which is not toxic, failed to generate any H2O2 and did not interact with copper. We conclude that the formation Of H202 from amylin could contribute to the progressive degeneration of islet cells in T213m. (c) 2007 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved

    The BaBar detector: Upgrades, operation and performance

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    Contains fulltext : 121729.pdf (preprint version ) (Open Access

    An integrated encyclopedia of DNA elements in the human genome.

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    The human genome encodes the blueprint of life, but the function of the vast majority of its nearly three billion bases is unknown. The Encyclopedia of DNA Elements (ENCODE) project has systematically mapped regions of transcription, transcription factor association, chromatin structure and histone modification. These data enabled us to assign biochemical functions for 80% of the genome, in particular outside of the well-studied protein-coding regions. Many discovered candidate regulatory elements are physically associated with one another and with expressed genes, providing new insights into the mechanisms of gene regulation. The newly identified elements also show a statistical correspondence to sequence variants linked to human disease, and can thereby guide interpretation of this variation. Overall, the project provides new insights into the organization and regulation of our genes and genome, and is an expansive resource of functional annotations for biomedical research

    Measurement of branching fractions for two-body charmless B decays to charged pions and kaons at BABAR

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    We present preliminary results of a search for charmless two-body B decays to charged pions and kaons using data collected by the BABAR detector at the Stanford Linear Accelerator Center's PEP-II storage ring. In a sample of 8.8 million produced B-anti-B pairs we measure the branching fractions B(B^0 --> pi^+pi^-) = (9.3^{+2.6}_{-2.3}^{+1.2}_{-1.4}) x 10^{-6} and B(B^0 --> K^+\pi^-) = (12.5^{+3.0}_{-2.6}^{+1.3}_{-1.7}) x 10^{-6}, where the first uncertainty is statistical and the second is systematic. For the decay B^0 --> K^+K^- we find no significant signal and set an upper limit of B(B^0 --> K^+K^-) 6.6 x 10^{-6} at the 90% confidence level

    A measurement of the charged and neutral B meson lifetimes using fully reconstructed decays

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    Data collected with the BABAR detector at the PEP-II asymmetric B Factory at SLAC are used to study the lifetimes of the B^0 and B^+ mesons. The data sample consists of 7.4 fb-1 collected near the Y(4S) resonance. B^0 and B^+ mesons are fully reconstructed in several exclusive hadronic decay modes to charm and charmonium final states. The B lifetimes are determined from the flight length difference between the two B mesons which are pair-produced in the Y(4S) decay. The preliminary measurements of the lifetimes are tau_B0 = 1.506+/-0.052(stat)+/-0.029(syst) ps, tau_B+ = 1.602+/-0.049(stat)+/-0.035(syst) ps, and of their ratio is tau_B+/tau_B0 = 1.065+/-0.044(stat)+/-0.021(syst
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