Influence Of Concentrate Levels In Diet And Body Biotypes On Productive Variables Of Guzera Beef Cattle

The goal of this study was evaluate diets (50 or 80% of concentrate) and body biotypes (late or early) on performance, behavior, carcass condition, meat quality, and feed cost estimates in feedlot finishing Guzera beef cattle. Use of concentrates in the diet may improve performance and carcass fat scores in ruminant animals, but Guzera beef cattle may be more efficient in forage conversion, which directly influences the economic viability of the production system. We evaluated 32 non-castrated male Guzera beef cattle at 32±2 months of age. The experimental design was completely randomized with four treatments and six replicates in a 2 × 2 factorial design (2 diets × 2 body biotypes). Initial and final body weights were 459.4±31.2 kg and 566.7±40.8 kg, respectively. There was no change (P > 0.05) in dry matter intake, feed conversion, or daily weight gain when the concentrate in the diet was increased to 80%. Animals fed a diet with 80% of concentrate spent less time (P < 0.05) ruminating (17.8±6.3 vs. 6.3±2.7% of the assessed time). Body biotype did not alter the variables. The rise from 50 to 80% in the proportion of dietary concentrate increased carcass fat, with positive returns in the production process, even given the reduction in rumination, which can lead to poor welfare of animals consuming 80% of dietary concentrate. Body biotype did not affect the variables studied, but it is worth emphasizing that the age at slaughter of these animals probably influenced this result. Thus, selection of the best diet should be based on feeding cost, and in accordance with the cost estimated in this study, the diet with 80% of concentrate is the most suitable for feedlot finished Guzera beef cattle.3764305431

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types

Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector

A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results

Jet size dependence of single jet suppression in lead-lead collisions at sqrt(s(NN)) = 2.76 TeV with the ATLAS detector at the LHC

Measurements of inclusive jet suppression in heavy ion collisions at the LHC provide direct sensitivity to the physics of jet quenching. In a sample of lead-lead collisions at sqrt(s) = 2.76 TeV corresponding to an integrated luminosity of approximately 7 inverse microbarns, ATLAS has measured jets with a calorimeter over the pseudorapidity interval |eta| < 2.1 and over the transverse momentum range 38 < pT < 210 GeV. Jets were reconstructed using the anti-kt algorithm with values for the distance parameter that determines the nominal jet radius of R = 0.2, 0.3, 0.4 and 0.5. The centrality dependence of the jet yield is characterized by the jet "central-to-peripheral ratio," Rcp. Jet production is found to be suppressed by approximately a factor of two in the 10% most central collisions relative to peripheral collisions. Rcp varies smoothly with centrality as characterized by the number of participating nucleons. The observed suppression is only weakly dependent on jet radius and transverse momentum. These results provide the first direct measurement of inclusive jet suppression in heavy ion collisions and complement previous measurements of dijet transverse energy imbalance at the LHC.Comment: 15 pages plus author list (30 pages total), 8 figures, 2 tables, submitted to Physics Letters B. All figures including auxiliary figures are available at http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/HION-2011-02