43 research outputs found

    Review Of E-Commerce Issues: Consumers Perception On Security And Privacy

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    Web security has been a major issue of debate in the recent years. The lack of security is perceived as a major stumbling block for doing business online. Electronic cash payment systems are becoming more important than ever to facilitate online transactions and thus replacing traditional payment methods such as checks The prime objective of this paper is to determine the perception of consumers towards the security aspects of e-commerce technology. Specifically this paper examines the perception and awareness of security from the consumers standpoint especially in recent e-business processes that facilitate transfer of payment via electronic systems such as e-wallet, credit card and e-cash. The paper also examines the measures that can be taken so that the mindset of users can be changed to suit this new on-line culture

    SOX2 Co-Occupies Distal Enhancer Elements with Distinct POU Factors in ESCs and NPCs to Specify Cell State

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    SOX2 is a master regulator of both pluripotent embryonic stem cells (ESCs) and multipotent neural progenitor cells (NPCs); however, we currently lack a detailed understanding of how SOX2 controls these distinct stem cell populations. Here we show by genome-wide analysis that, while SOX2 bound to a distinct set of gene promoters in ESCs and NPCs, the majority of regions coincided with unique distal enhancer elements, important cis-acting regulators of tissue-specific gene expression programs. Notably, SOX2 bound the same consensus DNA motif in both cell types, suggesting that additional factors contribute to target specificity. We found that, similar to its association with OCT4 (Pou5f1) in ESCs, the related POU family member BRN2 (Pou3f2) co-occupied a large set of putative distal enhancers with SOX2 in NPCs. Forced expression of BRN2 in ESCs led to functional recruitment of SOX2 to a subset of NPC-specific targets and to precocious differentiation toward a neural-like state. Further analysis of the bound sequences revealed differences in the distances of SOX and POU peaks in the two cell types and identified motifs for additional transcription factors. Together, these data suggest that SOX2 controls a larger network of genes than previously anticipated through binding of distal enhancers and that transitions in POU partner factors may control tissue-specific transcriptional programs. Our findings have important implications for understanding lineage specification and somatic cell reprogramming, where SOX2, OCT4, and BRN2 have been shown to be key factors

    A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic.

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    The COVID-19 pandemic has increased negative emotions and decreased positive emotions globally. Left unchecked, these emotional changes might have a wide array of adverse impacts. To reduce negative emotions and increase positive emotions, we tested the effectiveness of reappraisal, an emotion-regulation strategy that modifies how one thinks about a situation. Participants from 87 countries and regions (n = 21,644) were randomly assigned to one of two brief reappraisal interventions (reconstrual or repurposing) or one of two control conditions (active or passive). Results revealed that both reappraisal interventions (vesus both control conditions) consistently reduced negative emotions and increased positive emotions across different measures. Reconstrual and repurposing interventions had similar effects. Importantly, planned exploratory analyses indicated that reappraisal interventions did not reduce intentions to practice preventive health behaviours. The findings demonstrate the viability of creating scalable, low-cost interventions for use around the world

    Design and develop a device - jump robot

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    For this project “Design and Develop a Device”, the author decided on taking up the task to create a device that could jump. The primary objective was to build a prototype that could vertically jump as high as possible. Towards the end of the course of the project, the author explored the possibilities of the prototype performing a diagonal jump for application purposes. The author began the project by studying the prototypes completed by his predecessors and identified some of the underlying reasons why the results were not desirable. By avoiding similar mistakes, the first prototype built by the author managed to achieve a jump height of above 4 cm. The prototype relied on a battery powered motor to load a spring which provides the energy for the piston to strike the ground for the jump. Through several sets of improvements, which included weight reduction, increasing the spring force and improving on the consistency of the prototype in performing its jump, the prototype managed to achieve a final jump height of 8cm.Bachelor of Engineering (Mechanical Engineering

    SIR FRANK SWETTENHAM'S MALAYAN CAREER UP TO 1896

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    Master'sMASTER OF ART

    A History of Singapore

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    xx.442 hal.;ill.;25 c

    Foreword

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