Aplicaciones de software con tecnología NFC en dispositivos móviles, para niños con diversidad funcional

El creciente desarrollo de las neurociencias, en articulación con la práctica clínica profesional e interdisciplinaria y los avances tecnológicos, han abierto y enriquecido las herramientas disponibles para el abordaje e intervención de las personas con TEA, como así también de otros trastornos del desarrollo, añadiendo nuevos recursos y herramientas de apoyo. Es desde allí, que la incorporación del uso de la tecnología NFC, en dispositivos móviles, para niños con diversidad funcional, puede tornarse un aporte para terapeutas, docentes y familias. Nuestro enfoque teórico parte del manual diagnostico DSM V y la Teoría de la mente de Barón-Cohen. Siendo por lo general, las conductas de las personas con autismo de características rígidas, es que los cambios los pueden afectar significativamente. Por ello, este abordaje prevé el uso del recurso de secuencias temporales para atender a las necesidades de cada niño de forma anticipada y sistemática. Asimismo, el uso de la tecnología NFC puede tornarse también un instrumento medidor y habilitante entre el niño, sus necesidades e intereses y el medio. Finalmente, se prevé que esta experiencia pueda inaugurar el diseño de nuevas propuestas de actividades de transferencia tecnológica a otros campos de aplicación.Eje: Innovación en Educación en Informática.Red de Universidades con Carreras en Informática (RedUNCI

Aplicaciones de software con tecnología NFC en dispositivos móviles, para niños con diversidad funcional

El creciente desarrollo de las neurociencias, en articulación con la práctica clínica profesional e interdisciplinaria y los avances tecnológicos, han abierto y enriquecido las herramientas disponibles para el abordaje e intervención de las personas con TEA, como así también de otros trastornos del desarrollo, añadiendo nuevos recursos y herramientas de apoyo. Es desde allí, que la incorporación del uso de la tecnología NFC, en dispositivos móviles, para niños con diversidad funcional, puede tornarse un aporte para terapeutas, docentes y familias. Nuestro enfoque teórico parte del manual diagnostico DSM V y la Teoría de la mente de Barón-Cohen. Siendo por lo general, las conductas de las personas con autismo de características rígidas, es que los cambios los pueden afectar significativamente. Por ello, este abordaje prevé el uso del recurso de secuencias temporales para atender a las necesidades de cada niño de forma anticipada y sistemática. Asimismo, el uso de la tecnología NFC puede tornarse también un instrumento medidor y habilitante entre el niño, sus necesidades e intereses y el medio. Finalmente, se prevé que esta experiencia pueda inaugurar el diseño de nuevas propuestas de actividades de transferencia tecnológica a otros campos de aplicación.Eje: Innovación en Educación en Informática.Red de Universidades con Carreras en Informática (RedUNCI

Aplicaciones de software con tecnología NFC en dispositivos móviles, para niños con diversidad funcional

El creciente desarrollo de las neurociencias, en articulación con la práctica clínica profesional e interdisciplinaria y los avances tecnológicos, han abierto y enriquecido las herramientas disponibles para el abordaje e intervención de las personas con TEA, como así también de otros trastornos del desarrollo, añadiendo nuevos recursos y herramientas de apoyo. Es desde allí, que la incorporación del uso de la tecnología NFC, en dispositivos móviles, para niños con diversidad funcional, puede tornarse un aporte para terapeutas, docentes y familias. Nuestro enfoque teórico parte del manual diagnostico DSM V y la Teoría de la mente de Barón-Cohen. Siendo por lo general, las conductas de las personas con autismo de características rígidas, es que los cambios los pueden afectar significativamente. Por ello, este abordaje prevé el uso del recurso de secuencias temporales para atender a las necesidades de cada niño de forma anticipada y sistemática. Asimismo, el uso de la tecnología NFC puede tornarse también un instrumento medidor y habilitante entre el niño, sus necesidades e intereses y el medio. Finalmente, se prevé que esta experiencia pueda inaugurar el diseño de nuevas propuestas de actividades de transferencia tecnológica a otros campos de aplicación.Eje: Innovación en Educación en Informática.Red de Universidades con Carreras en Informática (RedUNCI

Kinetic modeling of carbon dioxide valorization with epoxides

The reaction between carbon dioxide and epoxides using a non-metallic catalytic system can produce cyclic carbonates with excellent yields. The activation of the chemical system can occur in two ways: activation of epoxide or activation of carbon dioxide at the first step. A kinetic investigation of epichlorohydrin carbonate synthesis from epichlorohydrin and carbon dioxide was performed. The mass transfer, the kinetic of reaction and the activation of the chemical system was included in the analysis. A kinetic model was developed based on the reaction mechanism and the mass transfer phenomena. The quasi steady state assumption was considered on intermediate species and its results were compared with the detailed model. The optimization of the kinetic parameters estimated was performed by using a genetic algorithm in the model, the results obtained were in agreement with the experimental data. Please click Additional Files below to see the full abstract

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

Gestión del conocimiento: perspectiva multidisciplinaria. Volumen 12

El libro “Gestión del Conocimiento. Perspectiva Multidisciplinaria”, Volumen 12, de la Colección Unión Global, es resultado de investigaciones. Los capítulos del libro, son resultados de investigaciones desarrolladas por sus autores. El libro cuenta con el apoyo de los grupos de investigación: Universidad Sur del Lago “Jesús María Semprúm” (UNESUR), Zulia – Venezuela; Universidad Politécnica Territorial de Falcón Alonso Gamero (UPTAG), Falcón – Venezuela; Universidad Politécnica Territorial de Mérida Kleber Ramírez (UPTM), Mérida – Venezuela; Universidad Guanajuato (UG) - Campus Celaya - Salvatierra - Cuerpo Académico de Biodesarrollo y Bioeconomía en las Organizaciones y Políticas Públicas (C.A.B.B.O.P.P), Guanajuato – México; Centro de Altos Estudios de Venezuela (CEALEVE), Zulia – Venezuela, Centro Integral de Formación Educativa Especializada del Sur (CIFE - SUR) - Zulia - Venezuela, Centro de Investigaciones Internacionales SAS (CIN), Antioquia - Colombia.y diferentes grupos de investigación del ámbito nacional e internacional que hoy se unen para estrechar vínculos investigativos, para que sus aportes científicos formen parte de los libros que se publiquen en formatos digital e impreso

Capture and valorisation of CO2 by using a chemical way : application to the synthesis of cyclic carbonates from epoxides

L'utilisation du CO2 comme matière première pour la synthèse de produits à haute valeur ajoutée, comme les carbonates cycliques, est aujourd'hui l'une des alternatives proposées dans la réduction des émissions gazeuses à effet de serre. Ce travail de thèse vise à comprendre et concevoir un procédé de valorisation de CO2 à partir de la modélisation de la thermodynamique et des cinétiques de transfert de matière et de réactions, qui sont engendrées dans la synthèse de carbonates cycliques à partir des époxydes et un composé hétérocyclique comme catalyseur. Grâce à ce nouveau système, les carbonates cycliques très utilisés dans l'industrie de polymères, cosmétique ou pharmaceutique, sont obtenus avec de bons rendements, dans des conditions opératoires douces et en absence de solvants. Des propriétés thermodynamiques telles que la solubilité et la constante de Henry ont été estimées pour les systèmes binaires CO2/époxyde. L'étude du transfert de matière sans ou avec réactions a permis de déterminer respectivement le coefficient de transfert de matière en phase liquide et le régime de la réaction. Des suivis cinétiques ont été réalisés afin de proposer un modèle cinétique capable de représenter la réaction et d'estimer les paramètres cinétiques. Ces derniers ont été utilisés pour la conception préliminaire et la simulation du procédé de production du carbonate d' épichlorohydrine sur Aspen Hysys.Today, the utilisation of CO2 as raw material for the synthesis of high-value added products like cyclic carbonates, is one of the alternatives used for reducing greenhouse gases. This thesis aims to understand and design a CO2 valorisation process by modelling the thermodynamic and the mass transfer/reaction kinetics generated during the cyclic carbonates synthesis from CO2, epoxides and a heterocyclic compound as catalyst. By using this new catalytic system, cyclic carbonates, which are used in the polymeric, pharmaceutic or cosmetic industry, can be produced with good yields at low temperatures and pressures and without any solvent. Thermodynamic properties as solubility and Henry's law constant have been estimated for CO2/epoxide binary systems. Mass transfer occurring without and with reaction has been studied in order to determine respectively the liquid volumetric mass transfer coefficient and the reaction regime. A kinetic study has been performed to propose a model able to represent the reaction and to estimate the kinetic parameters. This information has been used in the design and the simulation of the production process of epichlorohydrin carbonate on Aspen Hysys

Captage et valorisation du CO2 par voie chimique : application à la synthèse de carbonates cycliques à partir d’époxydes

Today, the utilisation of CO2 as raw material for the synthesis of high-value added products like cyclic carbonates, is one of the alternatives used for reducing greenhouse gases. This thesis aims to understand and design a CO2 valorisation process by modelling the thermodynamic and the mass transfer/reaction kinetics generated during the cyclic carbonates synthesis from CO2, epoxides and a heterocyclic compound as catalyst. By using this new catalytic system, cyclic carbonates, which are used in the polymeric, pharmaceutic or cosmetic industry, can be produced with good yields at low temperatures and pressures and without any solvent. Thermodynamic properties as solubility and Henry's law constant have been estimated for CO2/epoxide binary systems. Mass transfer occurring without and with reaction has been studied in order to determine respectively the liquid volumetric mass transfer coefficient and the reaction regime. A kinetic study has been performed to propose a model able to represent the reaction and to estimate the kinetic parameters. This information has been used in the design and the simulation of the production process of epichlorohydrin carbonate on Aspen Hysys.L'utilisation du CO2 comme matière première pour la synthèse de produits à haute valeur ajoutée, comme les carbonates cycliques, est aujourd'hui l'une des alternatives proposées dans la réduction des émissions gazeuses à effet de serre. Ce travail de thèse vise à comprendre et concevoir un procédé de valorisation de CO2 à partir de la modélisation de la thermodynamique et des cinétiques de transfert de matière et de réactions, qui sont engendrées dans la synthèse de carbonates cycliques à partir des époxydes et un composé hétérocyclique comme catalyseur. Grâce à ce nouveau système, les carbonates cycliques très utilisés dans l'industrie de polymères, cosmétique ou pharmaceutique, sont obtenus avec de bons rendements, dans des conditions opératoires douces et en absence de solvants. Des propriétés thermodynamiques telles que la solubilité et la constante de Henry ont été estimées pour les systèmes binaires CO2/époxyde. L'étude du transfert de matière sans ou avec réactions a permis de déterminer respectivement le coefficient de transfert de matière en phase liquide et le régime de la réaction. Des suivis cinétiques ont été réalisés afin de proposer un modèle cinétique capable de représenter la réaction et d'estimer les paramètres cinétiques. Ces derniers ont été utilisés pour la conception préliminaire et la simulation du procédé de production du carbonate d' épichlorohydrine sur Aspen Hysys

Captage et valorisation du CO2 par voie chimique : application à la synthèse de carbonates cycliques à partir d’époxydes

Today, the utilisation of CO2 as raw material for the synthesis of high-value added products like cyclic carbonates, is one of the alternatives used for reducing greenhouse gases. This thesis aims to understand and design a CO2 valorisation process by modelling the thermodynamic and the mass transfer/reaction kinetics generated during the cyclic carbonates synthesis from CO2, epoxides and a heterocyclic compound as catalyst. By using this new catalytic system, cyclic carbonates, which are used in the polymeric, pharmaceutic or cosmetic industry, can be produced with good yields at low temperatures and pressures and without any solvent. Thermodynamic properties as solubility and Henry's law constant have been estimated for CO2/epoxide binary systems. Mass transfer occurring without and with reaction has been studied in order to determine respectively the liquid volumetric mass transfer coefficient and the reaction regime. A kinetic study has been performed to propose a model able to represent the reaction and to estimate the kinetic parameters. This information has been used in the design and the simulation of the production process of epichlorohydrin carbonate on Aspen Hysys.L'utilisation du CO2 comme matière première pour la synthèse de produits à haute valeur ajoutée, comme les carbonates cycliques, est aujourd'hui l'une des alternatives proposées dans la réduction des émissions gazeuses à effet de serre. Ce travail de thèse vise à comprendre et concevoir un procédé de valorisation de CO2 à partir de la modélisation de la thermodynamique et des cinétiques de transfert de matière et de réactions, qui sont engendrées dans la synthèse de carbonates cycliques à partir des époxydes et un composé hétérocyclique comme catalyseur. Grâce à ce nouveau système, les carbonates cycliques très utilisés dans l'industrie de polymères, cosmétique ou pharmaceutique, sont obtenus avec de bons rendements, dans des conditions opératoires douces et en absence de solvants. Des propriétés thermodynamiques telles que la solubilité et la constante de Henry ont été estimées pour les systèmes binaires CO2/époxyde. L'étude du transfert de matière sans ou avec réactions a permis de déterminer respectivement le coefficient de transfert de matière en phase liquide et le régime de la réaction. Des suivis cinétiques ont été réalisés afin de proposer un modèle cinétique capable de représenter la réaction et d'estimer les paramètres cinétiques. Ces derniers ont été utilisés pour la conception préliminaire et la simulation du procédé de production du carbonate d' épichlorohydrine sur Aspen Hysys