124 research outputs found
Quaternion-Valued Breather Soliton, Rational, and Periodic KdV Solutions
Quaternion-valued solutions to the non-commutative KdV equation are produced
using determinants. The solutions produced in this way are (breather) soliton
solutions, rational solutions, spatially periodic solutions and hybrids of
these three basic types. A complete characterization of the parameters that
lead to non-singular 1-soliton and periodic solutions is given. Surprisingly,
it is shown that such solutions are never singular when the solution is
essentially non-commutative. When a 1-soliton solution is combined with another
solution through an iterated Darboux transformation, the result behaves
asymptotically like a combination of different solutions. This ``non-linear
superposition principle'' is used to find a formula for the phase shift in the
general 2-soliton interaction. A concluding section compares these results with
other research on non-commutative soliton equations and lists some open
questions
Current surgical practice for children born with a cleft lip and/or palate in the United Kingdom
Exploring the Relationship Between Palatal Cleft Type and Width With the Use of Relieving Incisions in Primary Repair
Landscape Epidemiology and Control of Pathogens with Cryptic and Long-Distance Dispersal: Sudden Oak Death in Northern Californian Forests
Exotic pathogens and pests threaten ecosystem service, biodiversity, and crop security globally. If an invasive agent can disperse asymptomatically over long distances, multiple spatial and temporal scales interplay, making identification of effective strategies to regulate, monitor, and control disease extremely difficult. The management of outbreaks is also challenged by limited data on the actual area infested and the dynamics of spatial spread, due to financial, technological, or social constraints. We examine principles of landscape epidemiology important in designing policy to prevent or slow invasion by such organisms, and use Phytophthora ramorum, the cause of sudden oak death, to illustrate how shortfalls in their understanding can render management applications inappropriate. This pathogen has invaded forests in coastal California, USA, and an isolated but fast-growing epidemic focus in northern California (Humboldt County) has the potential for extensive spread. The risk of spread is enhanced by the pathogen's generalist nature and survival. Additionally, the extent of cryptic infection is unknown due to limited surveying resources and access to private land. Here, we use an epidemiological model for transmission in heterogeneous landscapes and Bayesian Markov-chain-Monte-Carlo inference to estimate dispersal and life-cycle parameters of P. ramorum and forecast the distribution of infection and speed of the epidemic front in Humboldt County. We assess the viability of management options for containing the pathogen's northern spread and local impacts. Implementing a stand-alone host-free “barrier” had limited efficacy due to long-distance dispersal, but combining curative with preventive treatments ahead of the front reduced local damage and contained spread. While the large size of this focus makes effective control expensive, early synchronous treatment in newly-identified disease foci should be more cost-effective. We show how the successful management of forest ecosystems depends on estimating the spatial scales of invasion and treatment of pathogens and pests with cryptic long-distance dispersal
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Synthesis of an intriguing steroidal constitutional isomer
We recently described the synthesis of an unusual tricyclic system, whereby a cis-decalin was fused to a cis-hydrindane. Herein, we wish to describe the elaboration of this system towards steroid-like frameworks. This report describes how, en route to an attempted cardiotonic steroid synthesis, we stereoselectively functionalized the leftmost cyclohexyl ring with an ester ready for steroidal A-ring formation. Ultimately however, the required transposition of the cyclohexylketone did not occur as expected and resulted in the subsequent Robinson annulation forming an unusual steroidal constitutional isomer – the saturated cyclopenta[c]phenanthrene. Remarkably, such unusual tetracyclic connectivity has been reported just once in 70 years
Diurnal to interannual rainfall δ18O variations in northern Borneo driven by regional hydrology
The relationship between climate variability and rainfall oxygen isotopic (δ18O) variability is poorly constrained, especially in the tropics, where many key paleoclimate records rely on past rainfall isotopes as proxies for hydroclimate. Here we present a daily-resolved, 5-yr-long timeseries of rainfall δ18O from Gunung Mulu National Park, located in northern Borneo (4°N, 114°E) in the heart of the West Pacific Warm Pool, and compare it to local and regional climatic variables. Daily rainfall δ18O values range from +0.7‰ to -18.5‰ and exhibit a weak but significant inverse relationship with daily local precipitation amount (R=-0.19, p<0.05), consistent with the tropical amount effect. Day-to-day δ18O variability at Mulu is best correlated to regional precipitation amount averaged over the preceding week (R=-0.64, p<0.01). The inverse relationship between Mulu rainfall δ18O and local (regional) precipitation amount increases with increased temporal averaging, reaching R=-0.56 (R=-0.72) on monthly timescales. Large, negative, multi-day rainfall δ18O anomalies of up to 16‰ occur every 30-90 days and are closely associated with wet phases of the intraseasonal Madden-Julian Oscillation. A weak, semi-annual seasonal cycle in rainfall δ18O of 2-3‰ bears little resemblance to seasonal precipitation variability, pointing to a complex sequence of moisture sources and/or trajectories over the course of the year. Interannual rainfall δ18O variations of 6-8‰ are significantly correlated with indices of the El Niño Southern Oscillation, with increased rainfall δ18O during relatively dry El Niño conditions, and vice versa during La Nina events. We find that Mulu rainfall δ18O outperforms Mulu precipitation amount as a tracer of basin-scale climate variability, highlighting the time- and space-integrative nature of rainfall δ18O. Taken together, our results suggest that rainfall δ18O variability at Mulu is significantly influenced by the strength of regional convective activity. As such, our study provides further empirical support for the interpretation of δ18O-based paleo-reconstructions from northern Borneo stalagmites as robust indicators of regional-scale hydroclimate variability, where higher δ18O reflects regional dryin
Focused Ion Beam Microfabrication
Contains an introduction, reports on x research projects and a list of publications.Defense Advanced Research Projects Agency/U.S. Army Research Office Grant DAAL-03-92-G-0217National Science Foundation Grant ECS 89-21728Defense Advanced Research Projects Agency/U.S. Army Research Office (ASSERT Program) Grant DAAL03-92-G-0305Semiconductor Research CorporationNational Science Foundation Grant DMR 92-02633U.S. Army Research Office Grant DAAL03-90-G-0223U.S. Navy - Naval Research Laboratory/Micrion Contract M0877
Interlaboratory study for coral Sr/Ca and other element/Ca ratio measurements
The Sr/Ca ratio of coral aragonite is used to reconstruct past sea surface temperature (SST). Twentyone
laboratories took part in an interlaboratory study of coral Sr/Ca measurements. Results show
interlaboratory bias can be significant, and in the extreme case could result in a range in SST estimates of
7°C. However, most of the data fall within a narrower range and the Porites coral reference material JCp-
1 is now characterized well enough to have a certified Sr/Ca value of 8.838 mmol/mol with an expanded
uncertainty of 0.089 mmol/mol following International Association of Geoanalysts (IAG) guidelines.
This uncertainty, at the 95% confidence level, equates to 1.5°C for SST estimates using Porites, so is
approaching fitness for purpose. The comparable median within laboratory error is <0.5°C. This
difference in uncertainties illustrates the interlaboratory bias component that should be reduced through
the use of reference materials like the JCp-1. There are many potential sources contributing to biases in
comparative methods but traces of Sr in Ca standards and uncertainties in reference solution composition
can account for half of the combined uncertainty. Consensus values that fulfil the requirements to be
certified values were also obtained for Mg/Ca in JCp-1 and for Sr/Ca and Mg/Ca ratios in the JCt-1 giant
clam reference material. Reference values with variable fitness for purpose have also been obtained for
Li/Ca, B/Ca, Ba/Ca, and U/Ca in both reference materials. In future, studies reporting coral element/Ca
data should also report the average value obtained for a reference material such as the JCp-1
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A genomic storm in critically injured humans
Critical injury in humans induces a genomic storm with simultaneous changes in expression of innate and adaptive immunity genes
Denial of long-term issues with agriculture on tropical peatlands will have devastating consequences
Non peer reviewe
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