2,787 research outputs found

    Obonuco Andina nueva variedad mejorada de arveja para la zona de economía campesina del sur de Nariño.

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    El artículo presenta todas las características de la variedad mejorada de arveja, se muestra el origen genético, el comportamiento agronómico, los atributos culinarios, las cualidades de mercadeo, la descripción varietal, el manejo agronómico como la preparación del suelo, la fertilización, el sistema, densidad y época de siembra y el manejo de malezas, plagas y enfermedades y las conclusiones.Obonuco Andina, variedad mejorada de arveja para el sistema de economía campesina de Nariñ

    Derivation and external validation of the SIMPLICITY score as a simple immune-based risk score to predict infection in kidney transplant recipients

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    Existing approaches for infection risk stratification in kidney transplant recipients are suboptimal. Here, we aimed to develop and validate a weighted score integrating non-pathogen-specific immune parameters and clinical variables to predict the occurrence of post-transplant infectious complications. To this end, we retrospectively analyzed a single-center derivation cohort of 410 patients undergoing kidney transplantation in 2008-2013 in Madrid. Peripheral blood lymphocyte subpopulations, serum immunoglobulin and complement levels were measured at one-month post-transplant. The primary and secondary outcomes were overall and bacterial infection through month six. A point score was derived from a logistic regression model and prospectively applied on a validation cohort of 522 patients undergoing kidney transplantation at 16 centers throughout Spain in 2014-2015. The SIMPLICITY score consisted of the following variables measured at month one after transplantation: C3 level, CD4+ T-cell count, CD8+ T-cell count, IgG level, glomerular filtration rate, recipient age, and infection within the first month. The discrimination capacity in the derivation and validation cohorts was good for overall (areas under the receiver operating curve of 0.774 and 0.730) and bacterial infection (0.767 and 0.734, respectively). The cumulative incidence of overall infection significantly increased across risk categories in the derivation (low-risk 13.7%; intermediate-risk, 35.9%; high-risk 77.6%) and validation datasets (10.2%, 28.9% and 50.4%, respectively). Thus, the SIMPLICITY score, based on easily available immune parameters, allows for stratification of kidney transplant recipients at month one according to their expected risk of subsequent infection

    Long-term effect of 2 intensive statin regimens on treatment and incidence of cardiovascular events in familial hypercholesterolemia : The SAFEHEART study

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    Funding: This study was supported by Fundación Hipercolesterolemia Familiar; Grant G03/181 Grant 08-2008 Centro Nacional de Investigaci?n Cardiovascular (CNIC).Background: Maximal doses of potent statins are the basement of treatment of familial hypercholesterolemia (FH). Little is known about the use of different statin regimens in FH. Objectives: The objectives of the study were to describe the treatment changes and low-density lipoprotein cholesterol (LDL-C) goal achievement with atorvastatin (ATV) and rosuvastatin (RV) in the SAFEHEART cohort, as well as to analyze the incidence of atherosclerotic cardiovascular events (ACVEs) and changes in the cardiovascular risk. Methods: SAFEHEART is a prospective follow-up nationwide cohort study in a molecularly defined FH population. The patients were contacted on a yearly basis to obtain relevant changes in life habits, medication, and ACVEs. Results: A total of 1939 patients were analyzed. Median follow-up was 6.6 years (5-10). The estimated 10-year risk according the SAFEHEART risk equation was 1.61 (0.67-3.39) and 1.22 (0.54-2.93) at enrollment for ATV and RV, respectively (P <.001). There were no significant differences at the follow-up: 1.29 (0.54-2.82) and 1.22 (0.54-2.76) in the ATV and RV groups, respectively (P =.51). Sixteen percent of patients in primary prevention with ATV and 18% with RV achieved an LDL-C <100 mg/dL and 4% in secondary prevention with ATV and 5% with RV achieved an LDL-C <70 mg/dL. The use of ezetimibe was marginally greater in the RV group. One hundred sixty ACVEs occurred during follow-up, being its incidence rate 1.1 events/100 patient-years in the ATV group and 1.2 in the RV group (P =.58). Conclusion: ATV and RV are 2 high-potency statins widely used in FH. Although the reduction in LDL-C levels was greater with RV than with ATV, the superiority of RV for reducing ACVEs was not demonstrated

    Medición de captura y almacenamiento de carbono. Proyecto Charco Bendito. Modelo estratégico de restauración de microcuenca Cajititlán

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    El siguiente proyecto se realizó a partir del trabajo colaborativo realizado en el PAP Laboratorio de análisis de datos geoespaciales, el cual se centró en la identificación y análisis del carbono en el área de trabajo del proyecto “Charco Bendito” desarrollado por Red Bioterra SC. Se midieron los niveles de secuestro de carbono en el suelo del área trabajada por el equipo de Charco Bendito, esto con el propósito de conocer el secuestro antes del inicio del proyecto, tras haber limpiado la jarilla y plantar árboles endémicos. Además, se realizó una predicción a través de los datos adquiridos de cuál será el secuestro de carbono futuro del proyecto para el año 2028, y se analizará la cantidad de dólares ganados por la captura de carbono. Los objetivos anteriores se llevaron a cabo analizando las imágenes de satélite Sentinel-2 (teledetección) utilizando el software de código abierto QGIS. A partir de este trabajo, se realiza el modelado matemático del precio del carbono capturado, utilizando la herramienta de software libre InVEST, haciendo uso de sus tres modelos matemáticos y seleccionando aquel que otorgó mejores resultados. El motivo por el que se realiza el proyecto cuenta con aspectos tanto sociales como económicos. En el aspecto económico, se cuenta con las ganancias adquiridas de los bonos de carbono. El aspecto social, por su parte, en la mitigación del cambio climático a través de la restauración de los bosques. La dificultad se encuentra en la medición del carbono almacenado tanto en los bosques como suelos y demás flora con la que se cuenta. Para facilitar este procedimiento, se utilizarán las imágenes de satélite y algoritmos de análisis determinando la cantidad de carbono almacenado por pixel en las imágenes proporcionando un resultado más preciso a corto plazo y con mínimo costo. Se aplicó la metodología geoespacial recomendada para establecer el sistema de monitoreo, reporte y verificación por el (INECC-SEMARNAT, 2018) en el que la aportación de las ciencias geoespaciales contribuye con la representación espacial de los cambios en todos los periodos se hace en los mapas de cambio obtenidos a través de la sobreposición de mapas de vegetación. Cada uno alimenta una matriz de transición y con ellos se obtienen los datos de actividad para cada transición, en esencia así es como funciona el modelo InVEST. Los propósitos de este proyecto se enfocan en generar la información de interés para Red Bioterra con respecto al secuestro de carbono en su área de trabajo. Además de analizar las ganancias a adquirir de los bonos de carbono identificados, monetizados con el uso de datos de sistemas de comercio de emisiones.ITESO, A.C

    A First Search for coincident Gravitational Waves and High Energy Neutrinos using LIGO, Virgo and ANTARES data from 2007

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    We present the results of the first search for gravitational wave bursts associated with high energy neutrinos. Together, these messengers could reveal new, hidden sources that are not observed by conventional photon astronomy, particularly at high energy. Our search uses neutrinos detected by the underwater neutrino telescope ANTARES in its 5 line configuration during the period January - September 2007, which coincided with the fifth and first science runs of LIGO and Virgo, respectively. The LIGO-Virgo data were analysed for candidate gravitational-wave signals coincident in time and direction with the neutrino events. No significant coincident events were observed. We place limits on the density of joint high energy neutrino - gravitational wave emission events in the local universe, and compare them with densities of merger and core-collapse events.Comment: 19 pages, 8 figures, science summary page at http://www.ligo.org/science/Publication-S5LV_ANTARES/index.php. Public access area to figures, tables at https://dcc.ligo.org/cgi-bin/DocDB/ShowDocument?docid=p120000

    Swift follow-up observations of candidate gravitational-wave transient events

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    We present the first multi-wavelength follow-up observations of two candidate gravitational-wave (GW) transient events recorded by LIGO and Virgo in their 2009-2010 science run. The events were selected with low latency by the network of GW detectors and their candidate sky locations were observed by the Swift observatory. Image transient detection was used to analyze the collected electromagnetic data, which were found to be consistent with background. Off-line analysis of the GW data alone has also established that the selected GW events show no evidence of an astrophysical origin; one of them is consistent with background and the other one was a test, part of a "blind injection challenge". With this work we demonstrate the feasibility of rapid follow-ups of GW transients and establish the sensitivity improvement joint electromagnetic and GW observations could bring. This is a first step toward an electromagnetic follow-up program in the regime of routine detections with the advanced GW instruments expected within this decade. In that regime multi-wavelength observations will play a significant role in completing the astrophysical identification of GW sources. We present the methods and results from this first combined analysis and discuss its implications in terms of sensitivity for the present and future instruments.Comment: Submitted for publication 2012 May 25, accepted 2012 October 25, published 2012 November 21, in ApJS, 203, 28 ( http://stacks.iop.org/0067-0049/203/28 ); 14 pages, 3 figures, 6 tables; LIGO-P1100038; Science summary at http://www.ligo.org/science/Publication-S6LVSwift/index.php ; Public access area to figures, tables at https://dcc.ligo.org/cgi-bin/DocDB/ShowDocument?docid=p110003

    Sensitivity to Gravitational Waves from Compact Binary Coalescences Achieved during LIGO's Fifth and Virgo's First Science Run

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    We summarize the sensitivity achieved by the LIGO and Virgo gravitational wave detectors for compact binary coalescence (CBC) searches during LIGO's fifth science run and Virgo's first science run. We present noise spectral density curves for each of the four detectors that operated during these science runs which are representative of the typical performance achieved by the detectors for CBC searches. These spectra are intended for release to the public as a summary of detector performance for CBC searches during these science runs.Comment: 12 pages, 5 figure

    Search for Gravitational Waves from Low Mass Compact Binary Coalescence in LIGO's Sixth Science Run and Virgo's Science Runs 2 and 3

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    We report on a search for gravitational waves from coalescing compact binaries using LIGO and Virgo observations between July 7, 2009 and October 20, 2010. We searched for signals from binaries with total mass between 2 and 25 solar masses; this includes binary neutron stars, binary black holes, and binaries consisting of a black hole and neutron star. The detectors were sensitive to systems up to 40 Mpc distant for binary neutron stars, and further for higher mass systems. No gravitational-wave signals were detected. We report upper limits on the rate of compact binary coalescence as a function of total mass, including the results from previous LIGO and Virgo observations. The cumulative 90%-confidence rate upper limits of the binary coalescence of binary neutron star, neutron star- black hole and binary black hole systems are 1.3 x 10^{-4}, 3.1 x 10^{-5} and 6.4 x 10^{-6} Mpc^{-3}yr^{-1}, respectively. These upper limits are up to a factor 1.4 lower than previously derived limits. We also report on results from a blind injection challenge.Comment: 11 pages, 5 figures. For a repository of data used in the publication, go to: . Also see the announcement for this paper on ligo.org at: <http://www.ligo.org/science/Publication-S6CBCLowMass/index.php

    Detection of Spectral Variations of Anomalous Microwave Emission with QUIJOTE and C-BASS

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    Anomalous Microwave Emission (AME) is a significant component of Galactic diffuse emission in the frequency range 1010-6060\,GHz and a new window into the properties of sub-nanometre-sized grains in the interstellar medium. We investigate the morphology of AME in the 10\approx10^{\circ} diameter λ\lambda Orionis ring by combining intensity data from the QUIJOTE experiment at 1111, 1313, 1717 and 1919\,GHz and the C-Band All Sky Survey (C-BASS) at 4.764.76\,GHz, together with 19 ancillary datasets between 1.421.42 and 30003000\,GHz. Maps of physical parameters at 11^{\circ} resolution are produced through Markov Chain Monte Carlo (MCMC) fits of spectral energy distributions (SEDs), approximating the AME component with a log-normal distribution. AME is detected in excess of 20σ20\,\sigma at degree-scales around the entirety of the ring along photodissociation regions (PDRs), with three primary bright regions containing dark clouds. A radial decrease is observed in the AME peak frequency from 35\approx35\,GHz near the free-free region to 21\approx21\,GHz in the outer regions of the ring, which is the first detection of AME spectral variations across a single region. A strong correlation between AME peak frequency, emission measure and dust temperature is an indication for the dependence of the AME peak frequency on the local radiation field. The AME amplitude normalised by the optical depth is also strongly correlated with the radiation field, giving an overall picture consistent with spinning dust where the local radiation field plays a key role.Comment: 19 pages, 7 figures, accepted for publication by MNRA

    Implementation and testing of the first prompt search for gravitational wave transients with electromagnetic counterparts

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    Aims. A transient astrophysical event observed in both gravitational wave (GW) and electromagnetic (EM) channels would yield rich scientific rewards. A first program initiating EM follow-ups to possible transient GW events has been developed and exercised by the LIGO and Virgo community in association with several partners. In this paper, we describe and evaluate the methods used to promptly identify and localize GW event candidates and to request images of targeted sky locations. Methods. During two observing periods (Dec 17 2009 to Jan 8 2010 and Sep 2 to Oct 20 2010), a low-latency analysis pipeline was used to identify GW event candidates and to reconstruct maps of possible sky locations. A catalog of nearby galaxies and Milky Way globular clusters was used to select the most promising sky positions to be imaged, and this directional information was delivered to EM observatories with time lags of about thirty minutes. A Monte Carlo simulation has been used to evaluate the low-latency GW pipeline's ability to reconstruct source positions correctly. Results. For signals near the detection threshold, our low-latency algorithms often localized simulated GW burst signals to tens of square degrees, while neutron star/neutron star inspirals and neutron star/black hole inspirals were localized to a few hundred square degrees. Localization precision improves for moderately stronger signals. The correct sky location of signals well above threshold and originating from nearby galaxies may be observed with ~50% or better probability with a few pointings of wide-field telescopes.Comment: 17 pages. This version (v2) includes two tables and 1 section not included in v1. Accepted for publication in Astronomy & Astrophysic
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