112 research outputs found
Measurement of the scintillation time spectra and pulse-shape discrimination of low-energy beta and nuclear recoils in liquid argon with DEAP-1
The DEAP-1 low-background liquid argon detector was used to measure
scintillation pulse shapes of electron and nuclear recoil events and to
demonstrate the feasibility of pulse-shape discrimination (PSD) down to an
electron-equivalent energy of 20 keV.
In the surface dataset using a triple-coincidence tag we found the fraction
of beta events that are misidentified as nuclear recoils to be (90% C.L.) for energies between 43-86 keVee and for a nuclear recoil
acceptance of at least 90%, with 4% systematic uncertainty on the absolute
energy scale. The discrimination measurement on surface was limited by nuclear
recoils induced by cosmic-ray generated neutrons. This was improved by moving
the detector to the SNOLAB underground laboratory, where the reduced background
rate allowed the same measurement with only a double-coincidence tag.
The combined data set contains events. One of those, in the
underground data set, is in the nuclear-recoil region of interest. Taking into
account the expected background of 0.48 events coming from random pileup, the
resulting upper limit on the electronic recoil contamination is
(90% C.L.) between 44-89 keVee and for a nuclear recoil
acceptance of at least 90%, with 6% systematic uncertainty on the absolute
energy scale.
We developed a general mathematical framework to describe PSD parameter
distributions and used it to build an analytical model of the distributions
observed in DEAP-1. Using this model, we project a misidentification fraction
of approx. for an electron-equivalent energy threshold of 15 keV for
a detector with 8 PE/keVee light yield. This reduction enables a search for
spin-independent scattering of WIMPs from 1000 kg of liquid argon with a
WIMP-nucleon cross-section sensitivity of cm, assuming
negligible contribution from nuclear recoil backgrounds.Comment: Accepted for publication in Astroparticle Physic
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas
Integrative genomic and gene-expression analyses have identified amplified oncogenes in B-cell non-Hodgkin lymphoma (B-NHL), but the capability of such technologies to localize tumor suppressor genes within homozygous deletions remains unexplored. Array-based comparative genomic hybridization (CGH) and gene-expression microarray analysis of 48 cell lines derived from patients with different B-NHLs delineated 20 homozygous deletions at 7 chromosome areas, all of which contained tumor suppressor gene targets. Further investigation revealed that only a fraction of primary biopsies presented inactivation of these genes by point mutation or intragenic deletion, but instead some of them were frequently silenced by epigenetic mechanisms. Notably, the pattern of genetic and epigenetic inactivation differed among B-NHL subtypes. Thus, the P53-inducible PIG7/LITAF was silenced by homozygous deletion in primary mediastinal B-cell lymphoma and by promoter hypermethylation in germinal center lymphoma, the proapoptotic BIM gene presented homozygous deletion in mantle cell lymphoma and promoter hypermethylation in Burkitt lymphoma, the proapoptotic BH3-only NOXA was mutated and preferentially silenced in diffuse large B-cell lymphoma, and INK4c/P18 was silenced by biallelic mutation in mantle-cell lymphoma. Our microarray strategy has identified novel candidate tumor suppressor genes inactivated by genetic and epigenetic mechanisms that substantially vary among the B-NHL subtypes
Conception rate in Holstein cows treated with GnRH or hCG on the fifth day post artificial insemination during summer
Search for dark matter produced in association with a hadronically decaying vector boson in pp collisions at sqrt (s) = 13 TeV with the ATLAS detector
A search is presented for dark matter produced in association with a hadronically decaying W or Z boson using 3.2 fb−1 of pp collisions at View the MathML sources=13 TeV recorded by the ATLAS detector at the Large Hadron Collider. Events with a hadronic jet compatible with a W or Z boson and with large missing transverse momentum are analysed. The data are consistent with the Standard Model predictions and are interpreted in terms of both an effective field theory and a simplified model containing dark matter
Measurement of the νe and total 8B solar neutrino fluxes with the Sudbury Neutrino Observatory phase-III data set
This paper details the solar neutrino analysis of the 385.17-day phase-III data set acquired by the Sudbury Neutrino Observatory (SNO). An array of 3He proportional counters was installed in the heavy-water target to measure precisely the rate of neutrino-deuteron neutral-current interactions. This technique to determine the total active 8B solar neutrino flux was largely independent of the methods employed in previous phases. The total flux of active neutrinos was measured to be 5.54-0.31+0.33(stat.)-0.34+0.36(syst.)×106 cm-2 s-1, consistent with previous measurements and standard solar models. A global analysis of solar and reactor neutrino mixing parameters yielded the best-fit values of Δm2=7.59-0.21+0.19×10 -5eV2 and θ=34.4-1.2+1.3degrees
J/psi production as a function of charged-particle pseudorapidity density in p-Pb collisions at root s(NN)=5.02 TeV
We report measurements of the inclusive J/ψ yield and average transverse momentum as a function of charged-particle pseudorapidity density dNch/dη in p–Pb collisions at sNN=5.02TeV with ALICE at the LHC. The observables are normalised to their corresponding averages in non-single diffractive events. An increase of the normalised J/ψ yield with normalised dNch/dη, measured at mid-rapidity, is observed at mid-rapidity and backward rapidity. At forward rapidity, a saturation of the relative yield is observed for high charged-particle multiplicities. The normalised average transverse momentum at forward and backward rapidities increases with multiplicity at low multiplicities and saturates beyond moderate multiplicities. In addition, the forward-to-backward nuclear modification factor ratio is also reported, showing an increasing suppression of J/ψ production at forward rapidity with respect to backward rapidity for increasing charged-particle multiplicity
Parámetros electrocardiográficos del equino criollo de la región del piedemonte llanero
Titulo en ingles: Electrocardiographic parameters of creole equine from piedemonte of plains.RESUMEN Con en el fin de determinar los parámetros electrocardiográficos normales del equino criollo, de la zona del pie de monte llanero, de los departamentos de Arauca, Casanare y Meta, 340 equinos, distribuidos entre hembras, gestantes y vacías y machos, castrados y enteros, de diferentes edades, fueron sometidos a examen electrocardiográfico. La determinación y análisis de parámetros solo incluyó a la derivación bipolar D II. A través de los registros ECG se determinó para el total de la población en estudio diferentes parámetros tales como la frecuencia cardiaca, cuyo promedio general fue de 45.11 ± 10.75 lpm. El ritmo cardiaco mostró un patrón sinusal, el eje eléctrico promedio fue de 83.5 ± 73.2 grados, la onda P mostró una deflexión monofásica positiva, en un 75.9% de los casos. La amplitud de las ondas P, Q, R y T, arrojó promedios generales de 0.14 ± 0.06 mV, 0.24 ± 0.16 mV, 0.63 ± 0.31 mVy 0.12 ± 0.29 mV respectivamente.La onda T fue posi tiva en un 62.6% de los casos. La onda S no fue constante y solo se presentó en el 6% de los animales examinados. La duración promedio de las onda P, onda Q, complejo QRS y onda T fue de 0.06 ± 0.03 s, 0.09 ± 0.12 s, 0.16 ± 0.16 s y 0.1 ± 0.09 s respectivamente. La duración de los segmentosP-Q y S-T encontrados fue de 0.19 ± 0.06 s y 0.29 ±0.07 s en su orden y la duración de los intervalos P- Q y R-R, fueron de 0.22 ± 0.04 s y de 1.45 ± 0.25 s. Con las anteriores descripciones de parámetros del electrocardiograma equino, se han dado aproximaciones de su comportamiento en la región del pie de monte llanero, en animales criollos, que podrían ser considerados como normales tanto para los diferentes grupos establecidos, como para el total de la población estudiada en el presente trabajo.Palabras clave: electrocardiografía, caballo criollo.ABSTRACT: The aim of this work was to determine the normal electrocardiography parameters of native horses located in the Pie de Monte Llanero region, that included Arauca, Casanare and Meta Departments from Colombia. For this purpose, 340 animals distributed between stallion and gelding males, pregnant and no pregnant females, of different ages were accomplished to electrocardiographically exam. Analysis only included bipolar DII derivation. With the ECG records of total animals, different parameters were determined, like this: Heart rate, which general mean was 45.11 ± 10.75 bfm. Sinusal rhythm was the constant in all records and the Electric axe mean was of 83.5 ± 73.2 grades. 75.9% of the P wave showed positive monophasic curve. P, Q, R, and T waves amplitude showed general means of 0.14 ± 0.06 mV, 0.24 ± 0.16 mV, 0.63 ± 0.31 mV and 0.12 ± 0.29 mV, in this order. 62.6% of the T wave was positive. Only 6% of the records showed Swave. The duration of the P, Q, QRS and T waves had a general mean of the 0.06 ± 0.03s, 0.09 ± 0.12 s, 0.16 ± 0.16s and 0.1 ± 0.09s respectively. P-Q and S-T segments had duration of the 0.19 ± 0.06 s and 0.29 ± 0.07s in this order and the P-Q and R-R intervals duration was of 0.22 ± 0.04s and 1.45 ± 0.25s respectively. With these parameters of equine electrocardiography, we have done any advance about of its behavior in this zone of our country and in native horse, which could be considered as normal, both for different groups studied and for whole of population included in this studyTitulo en ingles: Electrocardiographic parameters of creole equine from piedemonte of plains.RESUMEN Con en el fin de determinar los parámetros electrocardiográficos normales del equino criollo, de la zona del pie de monte llanero, de los departamentos de Arauca, Casanare y Meta, 340 equinos, distribuidos entre hembras, gestantes y vacías y machos, castrados y enteros, de diferentes edades, fueron sometidos a examen electrocardiográfico. La determinación y análisis de parámetros solo incluyó a la derivación bipolar D II. A través de los registros ECG se determinó para el total de la población en estudio diferentes parámetros tales como la frecuencia cardiaca, cuyo promedio general fue de 45.11 ± 10.75 lpm. El ritmo cardiaco mostró un patrón sinusal, el eje eléctrico promedio fue de 83.5 ± 73.2 grados, la onda P mostró una deflexión monofásica positiva, en un 75.9% de los casos. La amplitud de las ondas P, Q, R y T, arrojó promedios generales de 0.14 ± 0.06 mV, 0.24 ± 0.16 mV, 0.63 ± 0.31 mVy 0.12 ± 0.29 mV respectivamente.La onda T fue posi tiva en un 62.6% de los casos. La onda S no fue constante y solo se presentó en el 6% de los animales examinados. La duración promedio de las onda P, onda Q, complejo QRS y onda T fue de 0.06 ± 0.03 s, 0.09 ± 0.12 s, 0.16 ± 0.16 s y 0.1 ± 0.09 s respectivamente. La duración de los segmentosP-Q y S-T encontrados fue de 0.19 ± 0.06 s y 0.29 ±0.07 s en su orden y la duración de los intervalos P- Q y R-R, fueron de 0.22 ± 0.04 s y de 1.45 ± 0.25 s. Con las anteriores descripciones de parámetros del electrocardiograma equino, se han dado aproximaciones de su comportamiento en la región del pie de monte llanero, en animales criollos, que podrían ser considerados como normales tanto para los diferentes grupos establecidos, como para el total de la población estudiada en el presente trabajo.Palabras clave: electrocardiografía, caballo criollo.ABSTRACT: The aim of this work was to determine the normal electrocardiography parameters of native horses located in the Pie de Monte Llanero region, that included Arauca, Casanare and Meta Departments from Colombia. For this purpose, 340 animals distributed between stallion and gelding males, pregnant and no pregnant females, of different ages were accomplished to electrocardiographically exam. Analysis only included bipolar DII derivation. With the ECG records of total animals, different parameters were determined, like this: Heart rate, which general mean was 45.11 ± 10.75 bfm. Sinusal rhythm was the constant in all records and the Electric axe mean was of 83.5 ± 73.2 grades. 75.9% of the P wave showed positive monophasic curve. P, Q, R, and T waves amplitude showed general means of 0.14 ± 0.06 mV, 0.24 ± 0.16 mV, 0.63 ± 0.31 mV and 0.12 ± 0.29 mV, in this order. 62.6% of the T wave was positive. Only 6% of the records showed Swave. The duration of the P, Q, QRS and T waves had a general mean of the 0.06 ± 0.03s, 0.09 ± 0.12 s, 0.16 ± 0.16s and 0.1 ± 0.09s respectively. P-Q and S-T segments had duration of the 0.19 ± 0.06 s and 0.29 ± 0.07s in this order and the P-Q and R-R intervals duration was of 0.22 ± 0.04s and 1.45 ± 0.25s respectively. With these parameters of equine electrocardiography, we have done any advance about of its behavior in this zone of our country and in native horse, which could be considered as normal, both for different groups studied and for whole of population included in this stud
Scapholunate Dissociation and Dorsal Intercalated Segmental Instability in an Adolescent Football Player
PD-0232: Multicentre validation of IMRT pre-treatment verification: onsite versus external audit
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