Nutraceutical Exploration of Wild Edible Fruits of District Tor Ghar, Nothern Pakistan

The present study deals with the exploration of wild edible fruits consumed by indigenous tribes in district Tor Ghar for curing different ailments. Wild edible fruits are potential source of nutrition and medicine. This is the first ethno-nutraceutical investigation of wild edible fruits of Tor Ghar. Local wisdom was interrogated by group discussions and semi structured interviews to assess the role of wild fruits in healthcare system of the region. Informants were randomly selected from five tribes of the district. It was found that the wild fruits have a great socioeconomic significance owing to their high nutritional and medicinal values. In the current study thirty eight wild edible fruits belonging to 29 genera and 22 families were documented for their ethno-nutraceutical importance. The study also revealed that general body weakness and digestive disorders are mostly cured by consuming wild edible fruits. The highest number of wild edible fruits belong to family Rosaceae (8 plant species). Popularity of wild edible plants among different tribes of Tor Ghar was assessed quantitatively by a statistical relation Fidelity level %age. Fidelity level index shows values for each species in descending order from Jugalans regia( 74.4%) to Buxus wallichiana (17.4%). The most popular wild edible fruit species was found Jugalans regia that scores highest fidelity level value

Nutraceutical Exploration of Wild Edible Fruits of District Tor Ghar, Nothern Pakistan

The present study deals with the exploration of wild edible fruits consumed by indigenous tribes in district Tor Ghar for curing different ailments. Wild edible fruits are potential source of nutrition and medicine. This is the first ethno-nutraceutical investigation of wild edible fruits of Tor Ghar. Local wisdom was interrogated by group discussions and semi structured interviews to assess the role of wild fruits in healthcare system of the region. Informants were randomly selected from five tribes of the district. It was found that the wild fruits have a great socioeconomic significance owing to their high nutritional and medicinal values. In the current study thirty eight wild edible fruits belonging to 29 genera and 22 families were documented for their ethno-nutraceutical importance. The study also revealed that general body weakness and digestive disorders are mostly cured by consuming wild edible fruits. The highest number of wild edible fruits belong to family Rosaceae (8 plant species). Popularity of wild edible plants among different tribes of Tor Ghar was assessed quantitatively by a statistical relation Fidelity level %age. Fidelity level index shows values for each species in descending order from Jugalans regia( 74.4%) to Buxus wallichiana (17.4%). The most popular wild edible fruit species was found Jugalans regia that scores highest fidelity level value

Efecto promotor del crecimiento de Pimpinella anisum (semilla de anis) en pollos broiler

Se realizó el presente estudio para evaluar el efecto promotor del crecimiento de Pimpinella anisum L. (anís) en pollos de  engorde en términos de ganancia de peso corporal, peso de los órganos, el consumo de alimento y conversión alimenticia (FCR). Para este  propósito, cuatro niveles (0,5, 1,0, 1,5 y 2,0 gramos por kg de alimento) de anís en polvo se administraron en el pienso desde el día 0 hasta  el final del experimento (42 días de edad). La ganancia de peso corporal, consumo de alimento y FCR fueron registrados en forma semanal.  Las aves mostraron un buen rendimiento (mejor ganancia de peso, un mejor consumo de alimento y FCR) cuando el anís se alimentó en  dosis más bajas, sin embargo, las aves mostraron malos resultados en los niveles más altos de anís. Del mismo modo, se observó casi el  mismo patrón de peso de los órganos. Este estudio sugiere que el buen efecto del anís en el rendimiento de pollos de engorde en dosis más  bajas que sugiere la necesidad adicional de experimentos de la serie para conocer los niveles de seguridad mínimos de anís que se  incorporarán en la ración de pollos de engorde para obtener los resultados deseados

Analysis of morphological traits in different host plants associated with resistance to Phenacoccus solenopsis- an invasive pest in Pakistan

Phenacoccus solenopsis Tinsley (Pseudococcidae: Hemiptera) is a sucking insect pest and is polyphagous in nature. Twenty five (25) different host plants were screened against P. solenopsis and their  physicomorphic traits were determined to correlate their role against pest population. Among the tested plant species, most favorable host plants of mealy bug on the basis of population were Gossypium hirsutum (69.74±10.5), Solamum melongena (62.41±10.0), Helianthus annuus (61.83±10.0), Hibiscus rosa-sinensis (61.1±10.0) and Lantana camara (55.83±9.75), but the least preferred plants were tandla Digera arvensis (1.57±1.00) and Conyza bonariensis (3.83±1.75). Significant variations were observed in all the morphological plant characters recorded from different plant species. The maximum leaf thickness per plant was 2.04±0.23 ìm in plant species S. melongena while minimum thickness of leaf was recorded from lehli (0.25±0.02 ìm). Maximum trichome density per plant was 444±72.4 in sunflower followed by 411.6±19.6, 399±52, 391.6±22.0, in C. bonariensis, Abelmoschus esculentus and Withania somnifera respectively but minimum were 2.33±1.45 in Chinopodium morale, followed by 2.66±1.4, and 3±2.08 in Portulaca oleracea and Trianthema portulacastrum respectively. The maximum hair length per plant (2.62±0.07 mm) was of sunflower followed by 2.55±0.03 mm in okra, 2.53±0.06 mm in both S. melongena and G. hirsutum. It was concluded that plant characters including trichome density and hair length favor mealy bug population showing r-values of 0.357* and 0.190 respectively but leaf size and leaf width (leaf area and leaf thickness) exerted negative effect on pest population showing r-values of -0.172 and -0.285 respectively.Key words: Phenacoccus solenopsis, invasive species, physicomorphic traits, resistance

Pharmacognostic, phytochemical, biological and spectroscopic analyses of Capparis decidua (Forsk.) Edgew root and stem bark

Purpose: To investigate the pharmacognostic, phytochemical, biological and spectroscopic analyses of Capparis decidua (Forsk.) Edgew root and stem bark.Methods: Plant material (root and stem bark) was collected, authenticated, shade-dried and extracted by maceration using methanol as a solvent separately. Powder microscopy was performed using a binocular microscope. Fluorescence, physico-chemical analysis and phytochemical screening for the presence of secondary metabolites were performed using standard methods. Brine shrimp lethalitybioassay was carried out using Artemia salina bioassay, while enzymatic modulatory study was performed by α-amylase inhibition assay. Microscopic analysis was carried out with scanning electron microscopy. Spectroscopic analysis was performed by Fourier transform infrared spectroscopy (FTIR).Results: Powder microscopy showed the presence of different cellular structures. Various colors were observed under ultraviolet (UV) and ordinary light when treated with different reagents. Phytochemical screening revealed the presence of alkaloids, tannins, saponins and flavonoids but phenol and cardiac glycosides were absent from both extracts. The root bark of the plant showed significant brine shrimp lethality activity.Conclusion: Capparis decidua (Forsk.) Edgew root and stem bark contain a variety of bioactive compounds that have medicinal and therapeutic potentials. Therefore, further investigations are required to elucidate their pharmacological properties. Keywords: Capparis decidua (Forsk.) Edgew, Phytochemical, Spectroscopy, α-Amylas

Comparison of nutrients uptake in different varieties of rice in Pakistan

The objective of this research was to determine the uptake of different elements (K, Mg, Ca, Na, Fe, Co, Mn, Pb, Cu, Zn and Ni) which are used as nutrients by the rice crop. Different types of rice seeds KSK-282, KSK-134, BAS-515, IR6, BAS-2000, KSK-133 and super-BAS were collected from National Agricultural Research Centre (NARC) Islamabad Pakistan and grown in different plastic pots containing soil under the same condition. Ten days old immature plants of different varieties of rice were dried and their roots were separated from the whole plants. The dried roots were ground into fine powder followed by acid digestion (HNO , H SO and 3 2 4 HClO ) solution in a ratio of (5:1:0.1) individually. After digestion the solutions were filtered and the filtrates 4 were diluted by adding distilled water. The diluted solutions of all the above mentioned varieties of rice were analyzed by Atomic Absorption Spectrophotometer (AAS) for nutrients (K, Mg, Ca, Na, Fe, Co, Mn, Pb, Cu, Zn and Ni) concentration. The different values obtained from AAS had shown that some rice varieties had taken up nutrients (elements) in large amount (e.g., KSK-134 had taken up maximum Fe while KSK-133 had taken up minimum) as compared to other varieties. Similarly, several verities absorbed comparatively minimum concentration of elements. The results obtained in this research work clearly indicated that the absorption of these elements from the soil was dependent on the rice variety (e.g., BAS-2000 absorbed maximum Mg while minimum Super-BAS). Interestingly most of the rice vaities had absorbed the beneficial elements in large quantity as compared to other toxic elements

ANTIVIRAL EFFECTS OF GREEN TEA (Camellia sinensis) AGAINST PATHOGENIC VIRUSES OF HUMAN AND ANIMALS (A MINIREVIEW)

Background: Tea is the second most addictive worldwide after formulations containing caffeine in carbonated beverage. Green tea is made from leaves of the Camellia sinensis plant. In the repertoire of traditional Chinese medicine, green tea beverages have played a fundamental role associated with their culture. It has been suggested that green tea has a number of positive health benefits that are reviewed and discussed in this minireview. Materials and Methods: We performed a search using the key words “green tea” AND “antiviral” covering the last 10 years. The consulted data based were PubMed, ISI Web of Knowledge, Scopus, Reuters and Thomson. Results: The results of the searching greatly support that green tea presents both antibacterial and antiviral effects. The beneficial effects of green tea are mainly attributed to the presence of a type of polyphenols known as catechins and formed by several isomers including (-) - epigallocatechin gallate (EGCG), (-) - epigallocatechin, (-) - epicatechin gallate, (-) -epicatechin, and (+) - catechin. The catechins in green tea have a wide range of antiviral activity against a variety of viruses that act by interfering with its replication cycle. Conclusion: A detailed information on the antiviral activity of green tea in a number of different viruses show a promising future as a popular drink and also as a potential therapeutic agent

Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990–2010 time period, with the greatest annualised rate of decline occurring in the 0–9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10–24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10–24 years were also in the top ten in the 25–49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50–74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation: As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and developm nt investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licens