Exhaled air analysis using wideband wave number tuning range infrared laser photoacoustic spectroscopy

The infrared laser photoacoustic spectroscopy (LPAS) and the pattern-recognition-based approach for noninvasive express diagnostics of pulmonary diseases on the basis of absorption spectra analysis of the patient’s exhaled air are presented. The study involved lung cancer patients ( N = 9 ), patients with chronic obstructive pulmonary disease ( N = 12 ), and a control group of healthy, nonsmoking volunteers ( N = 11 ). The analysis of the measured absorption spectra was based at first on reduction of the dimension of the feature space using principal component analysis; thereafter, the dichotomous classification was carried out using the support vector machine. The gas chromatography–mass spectrometry method (GC–MS) was used as the reference. The estimated mean value of the sensitivity of exhaled air sample analysis by the LPAS in dichotomous classification was not less than 90% and specificity was not less than 69%; the analogous results of analysis by GC–MS were 68% and 60%, respectively. Also, the approach to differential diagnostics based on the set of SVM classifiers usage is presented

Breath air measurement using wide-band frequency tuning IR laser photo-acoustic spectroscopy

The results of measuring of biomarkers in breath air of patients with broncho-pulmonary diseases using wide-band frequency tuning IR laser photo-acoustic spectroscopy and the methods of data mining are presented. We will discuss experimental equipment and various methods of intellectual analysis of the experimental spectra in context of above task

Inter-calibration of Infrared Channels of Geostationary Meteorological Satellite Imagers

This article examines a method of inter-calibration for MSU-GS imager of the Russian Geostationary Earth Orbit (GEO) satellite Elektro-L No. 2. Since the launch (December 11, 2015), the satellite's radiation cooler has been operating in an abnormal mode, so the calibration of the IR channels of the MSU-GS imager differed from that pre-flight and, in general, could have a daily variability. To ensure the satellite's further operation in orbit, it was necessary to calibrate imager channels at a frequency that would allow to identify daily calibration course to detect and compensate its sources. In order to do this, we have developed a special method of GEO-GEO inter-calibration. The calibration of MSU-GS was performed using SEVIRI imager installed on the GEO satellite Meteosat-10. SEVIRI was chosen as a reference instrument because its spectral channels are similar to those of MSU-GS. The MSU-GS was calibrated according to the regressions calculated from the simultaneous images of the field of regard selected between the sub-satellite points. The dynamic brightness temperature range was determined by deep convective clouds in high troposphere and warm ocean surface. Using the proposed method of inter-calibration, it was possible to confirm the absence of a significant daily variation of the calibration since November 2017. The amplitude of the variation smoothly increases from ~0.2 K at high (~300 K) BTs to ~1.0 K when the brightness temperature decreased to 200 K. These estimates allow the use of the Fourier spectrometer IKFS-2 installed on the Russian Low-Earth-Orbit (LEO) satellite Meteor-M No. 2 to verify the developed GEO-GEO scheme of inter-calibration. Despite the specifics of the situation on board Elektro-L No. 2, the proposed method of GEO-GEO inter-calibration can be applied to radiometers of other neighboring satellites that differ in SSP and spatial resolution

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements