The Child and Adult Care Food Program: Who is Served and What are Their Nutritional Outcomes?

This paper addresses three basic questions about an under-studied food subsidy program, the Child and Adult Care Food Program (CACFP): (1) Does CACFP reach targeted low-income children? (2) How do eligible families and child care providers who participate differ from those who do not participate? (3) What is the association between attending CACFP-participating child care and children's food intake, weight, and food security? We use the Early Childhood Longitudinal Study, Birth Cohort to examine these questions for a representative sample of young children and their providers. We find that program eligibility rules leave many poor children outside the CACFP program. Yet, among poor preschoolers in center-based care, participation in the program is correlated with positive outcomes such as increased consumption of milk and vegetables, and healthier weight (BMI). We discuss the implications of our findings, especially in relation to other food and child care subsidy programs.

Representation through Lived Experience: Expanding Representative Bureaucracy Theory

This study draws on the insights of managers in the behavioral health treatment system to explore the value of persons who bring lived experience to their organizational positions. Within these organizations, persons with relevant lived experience occupy various nonclinical and clinical positions. When facilities incorporate workers with lived experience, managers observe increased levels of trust between clients and service providers, an enhanced client-centered perspective among service providers, and higher quality in the services provided. This study may guide managers in considering how (or whether) human service organizations might institutionalize lived experience as a mechanism to help create a representative bureaucracy

HDL Subclass Proteomic Analysis and Functional Implication of Protein Dynamic Change During HDL Maturation

Recent clinical trials reported that increasing high-density lipoprotein-cholesterol (HDL-C) levels does not improve cardiovascular outcomes. We hypothesize that HDL proteome dynamics determine HDL cardioprotective functions. In this study, we characterized proteome profiles in HDL subclasses and established their functional connection. Mouse plasma was fractionized by fast protein liquid chromatography, examined for protein, cholesterial, phospholipid and trigliceride content. Small, medium and large (S/M/L)-HDL subclasseses were collected for proteomic analysis by mass spectrometry. Fifty-one HDL proteins (39 in S-HDL, 27 in M-HDL and 29 in L-HDL) were identified and grouped into 4 functional categories (lipid metabolism, immune response, coagulation, and others). Eleven HDL common proteins were identified in all HDL subclasses. Sixteen, 3 and 7 proteins were found only in S-HDL, M-HDL and L-HDL, respectively. We established HDL protein dynamic distribution in S/M/L-HDL and developed a model of protein composition change during HDL maturation. We found that cholesterol efflux and immune response are essential functions for all HDL particles, and amino acid metabolism is a special function of S-HDL, whereas anti-coagulation is special for M-HDL. Pon1 is recruited into M/L-HDL to provide its antioxidative function. ApoE is incorporated into L-HDL to optimize its cholesterial clearance function. Next, we acquired HDL proteome data from Pubmed and identified 12 replicated proteins in human and mouse HDL particle. Finally, we extracted 3 shared top moleccular pathways (LXR/RXR, FXR/RXR and acute phase response) for all HDL particles and 5 top disease/bio-functions differentially related to S/M/L-HDL subclasses, and presented one top net works for each HDL subclass. We conclude that beside their essencial functions of cholesterol efflux and immune response, HDL aquired antioxidative and cholesterol clearance functions by recruiting Pon1 and ApoE during HDL maturation

Uso del ensilado de Agave tequilana weber cv. azul en la alimentación de ovinos en crecimiento / Use of silage of Agave tequilana weber cv. blue in the feeding of growing lamb

El objetivo del presente estudio fue evaluar el comportamiento productivo de corderos en engorda, midiendo parámetros como el peso vivo (PV), la ganancia diaria de peso (GDP) y el consumo de alimento (CAL) en corderos alimentados con ensilado de hojas de Agave tequilana Weber cv azul.  Para evaluar el PV, la GDP y el CAL se utilizó un diseño factorial con medidas repetidas a través del tiempo.  Los datos obtenidos fueron analizados con el paquete estadístico del programa Statistical Analysis System (SAS; 1998), realizando una prueba de comparación de medias por el método de Tukey. Se utilizaron 20 corderos machos para la evaluación in vivo, asignados a cuatro tratamientos (T) con cinco repeticiones cada uno: T1 = 100% de alimento comercial (AC); T2 = 70% AC + 30% EA; T3 = 40% AC + 60% EA y T4 = 100% EA. El tiempo de engorda fue de 50 días, el cual se dividió en cinco periodos de 10 días cada uno.  Los resultados mostraron que no existió diferencia (P>0.05) entre los T1, T2 y T3 al analizar las medias generales de los tratamientos para la variable PV, sin embargo, el T4 si mostró diferencias (P<0.05) al tener el menor peso con relación al resto de los tratamientos. En cuanto a la GDP, los T1 y T2 fueron superiores a los T3 y T4 (P<0.05) siendo estor últimos los que presentan las menores ganancias de peso de manera general a lo largo del tiempo de engorda. En conclusión, los datos revelan que, adicionar 2% de urea en el ensilaje de hojas de Agave tequilana, incrementa de manera importante el contenido de PC y mejora la DIVMS, y que al administrar ese ensilado en una proporción de 30% EA + 70% AC se logran GDP similares a las obtenidas con una dieta a base de AC

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements