301 research outputs found
Mercury-Waterfilling for Generalized Multicarrier Signaling
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Effect Estimates in Randomized Trials and Observational Studies:Comparing Apples With Apples
- Author
- Abgrall S
- Babiker A
- Bucher HC
- Byrne D
- Chu H
- Cole SR
- Costagliola D
- Gill J
- Hernán MA
- Horban A
- INSIGHT START Study Group and the HIV-CAUSAL Collaboration
- Jarrin I
- Justice A
- Law M
- Lodi S
- Logan R
- Lundgren J
- Meyer L
- Montoliu Giménez A
- Neaton JD
- Pacheco AG
- Perez-Hoyos S
- Phillips A
- Porter K
- Reiss P
- Sabin C
- Sharma S
- Sterne JAC
- Touloumi G
- van Sighem A
- Wittkop L
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2019
- Field of study
Effect estimates from randomized trials and observational studies might not be directly comparable because of differences in study design, other than randomization, and in data analysis. We propose a 3-step procedure to facilitate meaningful comparisons of effect estimates from randomized trials and observational studies: 1) harmonization of the study protocols (eligibility criteria, treatment strategies, outcome, start and end of follow-up, causal contrast) so that the studies target the same causal effect, 2) harmonization of the data analysis to estimate the causal effect, and 3) sensitivity analyses to investigate the impact of discrepancies that could not be accounted for in the harmonization process. To illustrate our approach, we compared estimates of the effect of immediate with deferred initiation of antiretroviral therapy in individuals positive for the human immunodeficiency virus from the Strategic Timing of Antiretroviral Therapy (START) randomized trial and the observational HIV-CAUSAL Collaboration
Precise measurement of the W-boson mass with the CDF II detector
- Author
- Aaltonen T.
- Abbaneo D
- Adzic P
- Aguilar-Benitez M
- Ahmad M
- Ahmed I
- Albajar C
- Allfrey P
- Almeida N
- Alvarez Gonzalez B.
- Amerio S.
- Amidei D.
- Anastassov A.
- Andreev V
- Andreev Y
- Annovi A.
- Antos J.
- Apollinari G.
- Appel J. A.
- Arce P
- Arisawa T.
- Artikov A.
- Asaadi J.
- Asghar MI
- Ashmanskas W.
- Auerbach B.
- Auffray E
- Aurisano A.
- Auzinger G
- Azarkin M
- Azfar F.
- Azhgirey I
- Badgett W.
- Bae T.
- Baillon P
- Ball AH
- Barbaro-Galtieri A.
- Barnes V. E.
- Barnett B. A.
- Barney D
- Barria P.
- Bartos P.
- Battilana C
- Bauce M.
- Bedeschi F.
- Bedoya CF
- Beecher D.
- Behari S.
- Bell AJ
- Bellettini G.
- Bellinger J.
- Belotelov I
- Benedetti D
- Benjamin D.
- Beretvas A.
- Bernet C
- Bhatti A.
- Bialas W
- Bilinskas MJ
- Binkley M.
- Bisello D.
- Bitioukov S
- Bizjak I.
- Bland K. R.
- Bloch P
- Blumenfeld B.
- Bocci A
- Bocci A.
- Bodek A.
- Bolognesi S
- Bondar N
- Boos E
- Bortoletto D.
- Boudreau J.
- Boveia A.
- Breuker H
- Brigliadori L.
- Bromberg C.
- Brona G
- Brucken E.
- Budagov J.
- Budd H. S.
- Bunin P
- Bunkowski K
- Burelo ED
- Burkett K.
- Busetto G.
- Bussey P.
- Butler PH
- Buzatu A.
- Caballero IG
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- Calamba A.
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- Campderros JD
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- Cavaliere V.
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- Golovtsov V
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- Paramonov A. A.
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- Pardos CD
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- Pashenkov A
- Patrick J.
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- Piacentino G.
- Pianori E.
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- Qazi S
- Racz A
- Rahaman A.
- Ramakrishnan V.
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- Vila I.
- Vilar R.
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- Vlasov E
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- Volkov A
- Volodko A
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- Vorobyev A
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- Wakisaka T.
- Wallny R.
- Wallny R.
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- Wang S. M.
- Warburton A.
- Warburton A.
- Waters D.
- Waters D.
- Weinberger M.
- Wester W. C. III
- Wester W. C. III
- Whitehouse B.
- Whiteson D.
- Whiteson D.
- Wick F.
- Wick F.
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- Wicklund A. B.
- Wicklund E.
- Wicklund E.
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- Willmott C
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- Winer B. L.
- Winer B. L.
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- Wright T.
- Wrochna G
- Wu X.
- Wu X.
- Wu Z.
- Wu Z.
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- Yamaoka J.
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- Yang U. K.
- Yang U. K.
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- Yao W. -M.
- Yao W. -M.
- Yeh G. P.
- Yeh G. P.
- Yi K.
- Yi K.
- Yoh J.
- Yoh J.
- Yorita K.
- Yorita K.
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- Yoshida T.
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- Yun J. C.
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- Zalewski R
- Zanetti A.
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- Zeng Y.
- Zhokin A
- Zhou C.
- Zucchelli S..
- Zucchelli S..ng S
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
We have measured the W-boson mass MW using data corresponding to 2.2/fb of
integrated luminosity collected in proton-antiproton collisions at 1.96 TeV
with the CDF II detector at the Fermilab Tevatron collider. Samples consisting
of 470126 W->enu candidates and 624708 W->munu candidates yield the measurement
MW = 80387 +- 12 (stat) +- 15 (syst) = 80387 +- 19 MeV. This is the most
precise measurement of the W-boson mass to date and significantly exceeds the
precision of all previous measurements combined
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
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- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
- Akgun B
- Akgun U
- Akin IV
- Alagoz E
- Albajar C
- Albayrak EA
- Albergo S
- Albrow M
- Alda Junior WL
- Alexander J
- Aliev T
- Almeida N
- Alver B
- Alverson G
- Alves GA
- Amapane N
- Amsler C
- Anagnostou G
- Anastassov A
- Anderson J
- Anderson M
- Andrea J
- Andreev V
- Andreev V
- Andreev Y
- Andrews W
- Anghel IM
- Anjos TS
- Antonelli L
- Antunes JR
- Antunovic Z
- Apanasevich L
- Apollinari G
- Appelt E
- Apresyan A
- Aranyi A
- Arce P
- Arcidiacono R
- Arenton MW
- Arfaei H
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- Asghar MI
- Askew A
- Assran Y
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- Atramentov O
- Attikis A
- Auffray E
- Autermann C
- Auzinger G
- Avdeeva E
- Avery P
- Avetisyan A
- Azarkin M
- Azhgirey I
- Aziz T
- Azzi P
- Azzolini V
- Azzurri P
- Baarmand MM
- Babb J
- Bacchetta N
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- Baden A
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- Bai Y
- Baillon P
- Bainbridge R
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- Barbagli G
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- Basso L
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- Bauerdick LAT
- Baumgartel D
- Baur U
- Bayshev I
- Bazterra VE
- Bean A
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- Bedjidian M
- Beernaert K
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- Bellato M
- Bellinger JN
- Belotelov I
- Belyaev A
- Belyaev A
- Benaglia A
- Bencze G
- Bendavid J
- Benedetti D
- Benelli G
- Benhabib L
- Beni N
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- Benussi L
- Benvenuti AC
- Beranek S
- Beretvas A
- Bergauer T
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- Berzano U
- Besancon M
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- Bhat PC
- Bhatnagar V
- Bhattacharya S
- Bhattacharya S
- Bhatti A
- Bialas W
- Bialkowska H
- Bian JG
- Bianchi G
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- Biasini M
- Biino C
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- Bilin B
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- Biselli A
- Bisello D
- Bitioukov S
- Blekman F
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- Yilmaz Y
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- Yumiceva F
- Yun JC
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- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
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- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
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- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
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- Acosta MV
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- Chan M
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- Xiao H
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- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
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- Zoeller MH
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
X-ray emission from the Sombrero galaxy: discrete sources
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
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- Acosta MV
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- Adiguzel A
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- Breedon R
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- Brigliadori L
- Brigljevic V
- Broccolo G
- Brom JM
- Brona G
- Brooke JJ
- Broutin C
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- Brownson E
- Brun H
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- Butler PH
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- Bylsma B
- Caballero IG
- Cabrera A
- Cabrillo IJ
- Caebergs T
- Cakir A
- Calabria C
- Calderon A
- Cali IA
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- Caminada L
- Campagnari C
- Campbell A
- Campderros JD
- Camporesi T
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- Chang YH
- Chang YH
- Chang YW
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- Chao Y
- Charaf O
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- Chasco M
- Chatterjee A
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- Chen GM
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- Chuang SH
- Chung J
- Chung YS
- Chwalek T
- Ciesielski R
- Cifuentes JAB
- Cihangir S
- Cimmino A
- Cirino G
- Cittolin S
- Ciulli V
- Civinini C
- Claes DR
- Clare R
- Clarida W
- Clement E
- Clerbaux B
- Cline D
- CMS Collaboration
- Cockerill DJA
- Codispoti G
- Colafranceschi S
- Colaleo A
- Cole JE
- Cole P
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- Collard C
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- Conetti S
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- Cooper SI
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- Costantini S
- Coughlan JA
- Cousins R
- Covarelli R
- Cox B
- Cox PT
- Creanza D
- Cremaldi LM
- Cripps N
- Cuevas J
- Cuffiani M
- Cumalat JP
- Cuplov V
- Cure B
- Cushman P
- Cussans D
- Cutajar M
- Cutts D
- Cwiok M
- Czellar S
- D'Agnolo RT
- D'Alessandro R
- D'Alfonso M
- D'Enterria D
- D'Hondt J
- Da Costa EM
- Da Silva WLP
- Dahmes B
- Dahms T
- Dallavalle GM
- Damgov J
- Damiao DD
- Dammann D
- Danielson T
- Darmenov N
- Das S
- Daskalakis G
- Dasu S
- Daubie E
- David A
- Davids M
- Davies G
- De Araujo FTD
- de Barbaro P
- De Benedetti A
- De Boer W
- de Cassagnac RG
- De Cosa A
- de Fatis TT
- De Filippis N
- De Gruttola M
- De Guio F
- De Jeneret JD
- De La Cruz B
- De Lentdecker G
- De Mattia M
- de Monchenault GH
- De Palma M
- De Roeck A
- De Souza SF
- de Troconiz JF
- De Visscher S
- De Wolf EA
- Debreczeni G
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- Deiters K
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- Yilmaz Y
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- Zorbilmez C
- Zotto P
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- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2010
- Field of study
We present a study of discrete X-ray sources in and around the
bulge-dominated, massive Sa galaxy, Sombrero (M104), based on new and archival
Chandra observations with a total exposure of ~200 ks. With a detection limit
of L_X = 1E37 erg/s and a field of view covering a galactocentric radius of ~30
kpc (11.5 arcminute), 383 sources are detected. Cross-correlation with Spitler
et al.'s catalogue of Sombrero globular clusters (GCs) identified from HST/ACS
observations reveals 41 X-rays sources in GCs, presumably low-mass X-ray
binaries (LMXBs). We quantify the differential luminosity functions (LFs) for
both the detected GC and field LMXBs, whose power-low indices (~1.1 for the
GC-LF and ~1.6 for field-LF) are consistent with previous studies for
elliptical galaxies. With precise sky positions of the GCs without a detected
X-ray source, we further quantify, through a fluctuation analysis, the GC LF at
fainter luminosities down to 1E35 erg/s. The derived index rules out a
faint-end slope flatter than 1.1 at a 2 sigma significance, contrary to recent
findings in several elliptical galaxies and the bulge of M31. On the other
hand, the 2-6 keV unresolved emission places a tight constraint on the field
LF, implying a flattened index of ~1.0 below 1E37 erg/s. We also detect 101
sources in the halo of Sombrero. The presence of these sources cannot be
interpreted as galactic LMXBs whose spatial distribution empirically follows
the starlight. Their number is also higher than the expected number of cosmic
AGNs (52+/-11 [1 sigma]) whose surface density is constrained by deep X-ray
surveys. We suggest that either the cosmic X-ray background is unusually high
in the direction of Sombrero, or a distinct population of X-ray sources is
present in the halo of Sombrero.Comment: 11 figures, 5 tables, ApJ in pres
Performance of the CMS Cathode Strip Chambers with Cosmic Rays
- Author
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- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
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- Choudhury RK
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- Djordjevic M
- Do Amaral SMS
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- Zachariadou A
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- Zelepoukine S
- Zeuner WD
- Zeyrek M
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- Zhukova V
- Ziebarth EB
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- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2009
- Field of study
The Cathode Strip Chambers (CSCs) constitute the primary muon tracking device
in the CMS endcaps. Their performance has been evaluated using data taken
during a cosmic ray run in fall 2008. Measured noise levels are low, with the
number of noisy channels well below 1%. Coordinate resolution was measured for
all types of chambers, and fall in the range 47 microns to 243 microns. The
efficiencies for local charged track triggers, for hit and for segments
reconstruction were measured, and are above 99%. The timing resolution per
layer is approximately 5 ns
Measurement of jet fragmentation into charged particles in pp and PbPb collisions at sqrt(s[NN]) = 2.76 TeV
- Author
- Abbaneo D
- Abbiendi G
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- Yilmaz Y
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- Yumiceva F
- Yun JC
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- Zeyrek M
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- Zhukov V
- Zhukova V
- Zielinski M
- Zito G
- Zotto P
- Zou W
- Zucchetta A
- Zumerle G
- Zuranski A
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2012
- Field of study
Jet fragmentation in pp and PbPb collisions at a centre-of-mass energy of
2.76 TeV per nucleon pair was studied using data collected with the CMS
detector at the LHC. Fragmentation functions are constructed using
charged-particle tracks with transverse momenta pt > 4 GeV for dijet events
with a leading jet of pt > 100 GeV. The fragmentation functions in PbPb events
are compared to those in pp data as a function of collision centrality, as well
as dijet-pt imbalance. Special emphasis is placed on the most central PbPb
events including dijets with unbalanced momentum, indicative of energy loss of
the hard scattered parent partons. The fragmentation patterns for both the
leading and subleading jets in PbPb collisions agree with those seen in pp data
at 2.76 TeV. The results provide evidence that, despite the large parton energy
loss observed in PbPb collisions, the partition of the remaining momentum
within the jet cone into high-pt particles is not strongly modified in
comparison to that observed for jets in vacuum.Comment: Submitted to the Journal of High Energy Physic
Transcriptomic epidemiology of smoking: the effect of smoking on gene expression in lymphocytes
- Author
- A Heguy
- A Spira
- A Zeidel
- B Phillips
- BW Willemse
- CB Sherman
- CD Mathers
- CJ Meliska
- D Tang
- DM van Leeuwen
- DR Shopland
- EJ Perez-Stable
- Eric K Moses
- FJ Van Schooten
- GE Swan
- H Kiyosawa
- Harald HH Göring
- HH Göring
- J Beane
- Jac C Charlesworth
- Jack W Kent
- JC Rockett
- Jean W MacCluer
- JK Wiencke
- JM McCue
- Joanne E Curran
- John Blangero
- JT Williams
- JW Lampe
- JW MacCluer
- K Fagerstrom
- L Almasy
- Laura Almasy
- LM Lu
- M Lodovici
- M Sopori
- Matthew P Johnson
- MD Winniford
- MI Ryder
- Michael C Mahaney
- ML Sopori
- MS McPeek
- P Buttner
- P Moszczynski
- PA Newcomb
- PE McBride
- R Chari
- S Sridhar
- SL Baum
- Thomas D Dyer
- U.S. Department of Health and Human Services
- Vincent P Diego
- X Zhang
- Y Benjamini
- Y Geng
- Publication venue
- BioMed Central
- Publication date
- 01/01/2010
- Field of study
<p>Abstract</p> <p>Background</p> <p>This investigation offers insights into system-wide pathological processes induced in response to cigarette smoke exposure by determining its influences at the gene expression level.</p> <p>Methods</p> <p>We obtained genome-wide quantitative transcriptional profiles from 1,240 individuals from the San Antonio Family Heart Study, including 297 current smokers. Using lymphocyte samples, we identified 20,413 transcripts with significantly detectable expression levels, including both known and predicted genes. Correlation between smoking and gene expression levels was determined using a regression model that allows for residual genetic effects.</p> <p>Results</p> <p>With a conservative false-discovery rate of 5% we identified 323 unique genes (342 transcripts) whose expression levels were significantly correlated with smoking behavior. These genes showed significant over-representation within a range of functional categories that correspond well with known smoking-related pathologies, including immune response, cell death, cancer, natural killer cell signaling and xenobiotic metabolism.</p> <p>Conclusions</p> <p>Our results indicate that not only individual genes but entire networks of gene interaction are influenced by cigarette smoking. This is the largest <it>in vivo </it>transcriptomic epidemiological study of smoking to date and reveals the significant and comprehensive influence of cigarette smoke, as an environmental variable, on the expression of genes. The central importance of this manuscript is to provide a summary of the relationships between gene expression and smoking in this exceptionally large cross-sectional data set.</p
Alliances and the innovation performance of corporate and public research spin-off firms
- Author
- A Lindholm-Dahlstrand
- A Lockett
- A Tübke
- A Walter
- AC Cooper
- B Bienz-Tadmor
- B Callan
- B Clarysse
- B Gomes-Casseres
- BH Hall
- Boris Lokshin
- C Bessy
- C Freeman
- C Haeussler
- C Lechner
- C Schneider
- D Archibugi
- D Garvin
- D Iacobucci
- D Lavie
- D Maclean
- DC Mowery
- DC Mowery
- E Fauchart
- EG Carayannis
- Ernst & Young
- F Galia
- F Sorrentino
- F Visintin
- FT Rothaermel
- FT Rothaermel
- FT Rothaermel
- G Ahuja
- G George
- H Greve
- H Löfsten
- H Yang
- HY Kang
- I Neyens
- J Cohen
- J Hagedoorn
- J Lerner
- J Sedaitis
- J Senker
- J Zhang
- JA DiMasi
- JA DiMasi
- JAC Baum
- JAC Baum
- JF Forrest
- JM Podolny
- JM Unger
- John Hagedoorn
- JW Botkin
- K Pavitt
- K Wennberg
- KM Eisenhardt
- KY Kim
- L Perez
- M Andersson
- M Dahl
- M Dahl
- M Dowling
- M Freel
- M Geenhuizen van
- M Santoro
- M Schilling
- M Tripsas
- MD Ensley
- MG Colombo
- MJ Kelly
- MP Koza
- MT Dacin
- N Roijakkers
- N Rosenbuch
- P Bierly
- P Mustar
- P-J Benghozi
- PH Soh
- R Agarwal
- R Belderbos
- R Chen
- R Helm
- R Katila
- R Stankiewicz
- R Vandaie
- R Yagüe-Perales
- RC Sampson
- RG Cooper
- RS Rao
- S Klepper
- S Malo
- S Malo
- S Mosey
- S Mosey
- S Prashantham
- S Shane
- S Shane
- S Thomke
- S Zahra
- SA Alvarez
- Stéphane Malo
- T Khanna
- TE Stuart
- U Wassmer
- V Mohr
- V Scholten
- W Boeker
- W Shan
- W Zidorn
- WW Powell
- WW Powell
- Y Doz
- Y Hirai
- Z Griliches
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
We explore the innovation performance benefits of alliances for spin-off firms, in particular spin-offs either from other firms or from public research organizations. During the early years of the emerging combinatorial chemistry industry, the industry on which our empirical analysis focuses, spin-offs engaged in alliances with large and established partners, partners of similar type and size, and with public research organizations, often for different reasons. We seek to understand to what extent alliances of spin-offs with other firms (either large- or small- and medium-sized firms) affected their innovation performance and also how this performance may have been affected by their corporate or public research background. We find evidence that in general alliances of spin-offs with other firms, in particular alliances with large firms, increased their innovation performance. Corporate spin-offs that formed alliances with other firms outperformed public research spin-offs with such alliances. This suggests that, in terms of their innovation performance, corporate spin-offs that engaged in alliances with other firms seemed to have benefitted from their prior corporate background. Interestingly, it turns out that the negative impact of alliances on the innovation performance of public research spin-offs was largely affected by their alliances with small- and medium-sized firms
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