A survey on wireless ad hoc networks

A wireless ad hoc network is a collection of wireless nodes that can dynamically self-organize into an arbitrary and temporary topology to form a network without necessarily using any pre-existing infrastructure. These characteristics make ad hoc networks well suited for military activities, emergency operations, and disaster recoveries. Nevertheless, as electronic devices are getting smaller, cheaper, and more powerful, the mobile market is rapidly growing and, as a consequence, the need of seamlessly internetworking people and devices becomes mandatory. New wireless technologies enable easy deployment of commercial applications for ad hoc networks. The design of an ad hoc network has to take into account several interesting and difficult problems due to noisy, limited-range, and insecure wireless transmissions added to mobility and energy constraints. This paper presents an overview of issues related to medium access control (MAC), routing, and transport in wireless ad hoc networks and techniques proposed to improve the performance of protocols. Research activities and problems requiring further work are also presented. Finally, the paper presents a project concerning an ad hoc network to easily deploy Internet services on low-income habitations fostering digital inclusion8th IFIP/IEEE International conference on Mobile and Wireless CommunicationRed de Universidades con Carreras en Informática (RedUNCI

Wireless ad hoc networks on underserved communities: an efficient solution for interactive digital TV

The Brazilian government intends to use the Digital TV technology as a vehicle of digital inclusion on underserved communities. The wireless ad hoc network is a low-cost, scalable and easy solution to implement the return channel. This work analyzes the performance of an ad hoc return channel using the wireless IEEE 802.11 technology in different Brazilian geographical scenarios. The results show that a high connectivity is achieved when more than 20% of the nodes are turned on, regardless of the position of the gateway. The influence of the number of hops and the number of transmitting nodes is also analyzed. A minimum throughput of 2 Mbps can be reached for increasing number of hops in the forwarding chain for a one-node transmission. Besides, when the number of transmitting nodes increases, the aggregated throughput can achieve 3.5 Mbps. The results show that the ad hoc network is a promising solution for the return channel of the interactive Digital TV.8th IFIP/IEEE International conference on Mobile and Wireless CommunicationRed de Universidades con Carreras en Informática (RedUNCI

A survey on wireless ad hoc networks

A wireless ad hoc network is a collection of wireless nodes that can dynamically self-organize into an arbitrary and temporary topology to form a network without necessarily using any pre-existing infrastructure. These characteristics make ad hoc networks well suited for military activities, emergency operations, and disaster recoveries. Nevertheless, as electronic devices are getting smaller, cheaper, and more powerful, the mobile market is rapidly growing and, as a consequence, the need of seamlessly internetworking people and devices becomes mandatory. New wireless technologies enable easy deployment of commercial applications for ad hoc networks. The design of an ad hoc network has to take into account several interesting and difficult problems due to noisy, limited-range, and insecure wireless transmissions added to mobility and energy constraints. This paper presents an overview of issues related to medium access control (MAC), routing, and transport in wireless ad hoc networks and techniques proposed to improve the performance of protocols. Research activities and problems requiring further work are also presented. Finally, the paper presents a project concerning an ad hoc network to easily deploy Internet services on low-income habitations fostering digital inclusion8th IFIP/IEEE International conference on Mobile and Wireless CommunicationRed de Universidades con Carreras en Informática (RedUNCI

Wireless ad hoc networks on underserved communities: an efficient solution for interactive digital TV

The Brazilian government intends to use the Digital TV technology as a vehicle of digital inclusion on underserved communities. The wireless ad hoc network is a low-cost, scalable and easy solution to implement the return channel. This work analyzes the performance of an ad hoc return channel using the wireless IEEE 802.11 technology in different Brazilian geographical scenarios. The results show that a high connectivity is achieved when more than 20% of the nodes are turned on, regardless of the position of the gateway. The influence of the number of hops and the number of transmitting nodes is also analyzed. A minimum throughput of 2 Mbps can be reached for increasing number of hops in the forwarding chain for a one-node transmission. Besides, when the number of transmitting nodes increases, the aggregated throughput can achieve 3.5 Mbps. The results show that the ad hoc network is a promising solution for the return channel of the interactive Digital TV.8th IFIP/IEEE International conference on Mobile and Wireless CommunicationRed de Universidades con Carreras en Informática (RedUNCI

Inhibitors of trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease.

Chagas disease remains one of the most neglected diseases in the world despite being the most important parasitic disease in Latin America. The characteristic chronic manifestation of chagasic cardiomyopathy is the region's leading cause of heart-related illness, causing significant mortality and morbidity. Due to the limited available therapeutic options, new drugs are urgently needed to control the disease. Sirtuins, also called Silent information regulator 2 (Sir2) proteins have long been suggested as interesting targets to treat different diseases, including parasitic infections. Recent studies on Trypanosoma cruzi sirtuins have hinted at the possibility to exploit these enzymes as a possible drug targets. In the present work, the T. cruzi Sir2 related protein 1 (TcSir2rp1) is genetically validated as a drug target and biochemically characterized for its NAD+-dependent deacetylase activity and its inhibition by the classic sirtuin inhibitor nicotinamide, as well as by bisnaphthalimidopropyl (BNIP) derivatives, a class of parasite sirtuin inhibitors. BNIPs ability to inhibit TcSir2rp1, and anti-parasitic activity against T. cruzi amastigotes in vitro were investigated. The compound BNIP Spermidine (BNIPSpd) (9), was found to be the most potent inhibitor of TcSir2rp1. Moreover, this compound showed altered trypanocidal activity against TcSir2rp1 overexpressing epimastigotes and anti-parasitic activity similar to the reference drug benznidazole against the medically important amastigotes, while having the highest selectivity index amongst the compounds tested. Unfortunately, BNIPSpd failed to treat a mouse model of Chagas disease, possibly due to its pharmacokinetic profile. Medicinal chemistry modifications of the compound, as well as alternative formulations may improve activity and pharmacokinetics in the future. Additionally, an initial TcSIR2rp1 model in complex with p53 peptide substrate was obtained from low resolution X-ray data (3.5 Å) to gain insight into the potential specificity of the interaction with the BNIP compounds. In conclusion, the search for TcSir2rp1 specific inhibitors may represent a valuable strategy for drug discovery against T. cruzi

Genomic history of coastal societies from eastern South America

Sambaqui (shellmound) societies are among the most intriguing archaeological phenomena in pre-colonial South America, extending from approximately 8,000 to 1,000 years before present (yr bp) across 3,000 km on the Atlantic coast. However, little is known about their connection to early Holocene hunter-gatherers, how this may have contributed to different historical pathways and the processes through which late Holocene ceramists came to rule the coast shortly before European contact. To contribute to our understanding of the population history of indigenous societies on the eastern coast of South America, we produced genome-wide data from 34 ancient individuals as early as 10,000 yr bp from four different regions in Brazil. Early Holocene hunter-gatherers were found to lack shared genetic drift among themselves and with later populations from eastern South America, suggesting that they derived from a common radiation and did not contribute substantially to later coastal groups. Our analyses show genetic heterogeneity among contemporaneous Sambaqui groups from the southeastern and southern Brazilian coast, contrary to the similarity expressed in the archaeological record. The complex history of intercultural contact between inland horticulturists and coastal populations becomes genetically evident during the final horizon of Sambaqui societies, from around 2,200 yr bp, corroborating evidence of cultural change

Evidence for Reductive Genome Evolution and Lateral Acquisition of Virulence Functions in Two Corynebacterium pseudotuberculosis Strains

Ruiz JC, D'Afonseca V, Silva A, et al. Evidence for Reductive Genome Evolution and Lateral Acquisition of Virulence Functions in Two Corynebacterium pseudotuberculosis Strains. PLoS ONE. 2011;6(4): e18551.Background: Corynebacterium pseudotuberculosis, a Gram-positive, facultative intracellular pathogen, is the etiologic agent of the disease known as caseous lymphadenitis (CL). CL mainly affects small ruminants, such as goats and sheep; it also causes infections in humans, though rarely. This species is distributed worldwide, but it has the most serious economic impact in Oceania, Africa and South America. Although C. pseudotuberculosis causes major health and productivity problems for livestock, little is known about the molecular basis of its pathogenicity. Methodology and Findings: We characterized two C. pseudotuberculosis genomes (Cp1002, isolated from goats; and CpC231, isolated from sheep). Analysis of the predicted genomes showed high similarity in genomic architecture, gene content and genetic order. When C. pseudotuberculosis was compared with other Corynebacterium species, it became evident that this pathogenic species has lost numerous genes, resulting in one of the smallest genomes in the genus. Other differences that could be part of the adaptation to pathogenicity include a lower GC content, of about 52%, and a reduced gene repertoire. The C. pseudotuberculosis genome also includes seven putative pathogenicity islands, which contain several classical virulence factors, including genes for fimbrial subunits, adhesion factors, iron uptake and secreted toxins. Additionally, all of the virulence factors in the islands have characteristics that indicate horizontal transfer. Conclusions: These particular genome characteristics of C. pseudotuberculosis, as well as its acquired virulence factors in pathogenicity islands, provide evidence of its lifestyle and of the pathogenicity pathways used by this pathogen in the infection process. All genomes cited in this study are available in the NCBI Genbank database (http://www.ncbi.nlm.nih.gov/genbank/) under accession numbers CP001809 and CP001829

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Differential cross section measurements for the production of a W boson in association with jets in proton–proton collisions at √s = 7 TeV

Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript −1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio

Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good