1,911 research outputs found
Academic Genres and Federal State Educational Standard: on Course to Compromise
The article is devoted to the organization of work with postgraduate students of Russian universities. The urgency of the problem of teaching the principles of presentation of results of own research activities in written and oral form in Russian and foreign (English) languages is stated. The authors consider the generalization of learning objectives and equivalence of requirements for the mastery of the mother tongue and a foreign language in a modern high school standards at the stage of bachelor, master and PhD programs one of the important reasons that hinder the solution to the problem. Uneven number of hours distinguished for studying of Russian and foreign languages starting from the senior secondary school is also noted. Based on their long-time experience, the authors set out their vision of ways of solving this problem for the Russian audience. As a compromise in the existing conditions it is proposed to introduce for these categories of students the new integrated, bilingual course. The aim of the course is to help postgraduate students of different specialties in the preparation and publication of scientific works in Russian and English and to enable them part-time and full-time participation in conferences of Russian and international level. The choice of the course name and the components of its content is carried out taking into account the analysis of foreign experience and Russian rhetorical tradition. The authors’ development of the modules of the course “Scientific writing and scientific rhetoric” is presented, a brief description of their contents is given
Clinical and electro - anatomical characteristics of cognitive impairment in children with mental disontogeny
The results of clinical and electro-anatomical study of 100 preschool children with perinatal intensive care. According Intellectual test is divided into three groups - normal, delayed and deficient levels. The comparative clinical diagnostics with neurophysiological (EEG) and neuroanatomical (CT or MRI) correlates. The results show compliance of all the parameters of the degree of severity of the disorder and reflect the levels of damage in the cognitive mental disontogeny.Представлены результаты кпинико-электро-анатомического исследования 100 детей дошкольного возраста, перенесших перинатальную реанимацию. По данным интеллектуального теста выделены три группы - с нормальным, задержанным и дефектным уровнем. Проведена сравнительная диагностика клинической картины с нейрофизиологическими (ЭЭГ) и нейроанатомическими (КТ или МРТ) коррелятами. Полученные результаты свидетельствуют о соответствии всех представленных параметров степени тяжести расстройств и отражают уровни повреждения при когнитивном психическом дизонтогенезе
Clinical neuropsychologic characteristics of psychoorganic syndrome in children’s epilepsy
This work describes dynamics in clinical neuropsychologic characteristics of psychoorganic syndrome in children’s epilepsy. 156 children with epilepsy have been studied using clinical-anamnestic, clinical-psychopathologic, clinical-dynamic and neuropsychologic methods. We have analyzed clinical features of psychoorganic syndrome depending on time of epilepsy debut and studied dynamics of mental disorder. It was found that the earlier an epilepsy debut happens, the more serious mental disorders a child has. Clinical presentation of manifestation and generation of psychoorganic syndrome depends on stages of ontogenetic development. Neuropsychologic challenge correlates with clinical presentation of psychoorganic syndrome.Цель работы: В работе представлена динамика клинико-нейропсихологических характеристик психоорганического синдрома при эпилепсии у детей. С помощью клинико-анамнестического, клинико-психопатологического, клинико-динамического и нейропсихологического методов изучено 156 детей, страдающих эпилепсией. Были проанализированы клинические особенности психоорганического синдрома в зависимости от времени дебюта эпилепсии и рассмотрена динамика становления психической патологии. Определено, что чем раньше дебют эпилепсии, тем тяжелее психические нарушения. Клиническая картина манифестации и становления психоорганического синдрома зависели от этапов онтогенетического развития. Нейропсихологическая симптоматика коррелировала с клинической картиной психо-органического синдрома
Feasibility studies of the time-like proton electromagnetic form factor measurements with PANDA at FAIR
The possibility of measuring the proton electromagnetic form factors in the
time-like region at FAIR with the \PANDA detector is discussed. Detailed
simulations on signal efficiency for the annihilation of into a
lepton pair as well as for the most important background channels have been
performed. It is shown that precision measurements of the differential cross
section of the reaction can be obtained in a wide
angular and kinematical range. The individual determination of the moduli of
the electric and magnetic proton form factors will be possible up to a value of
momentum transfer squared of (GeV/c). The total cross section will be measured up to (GeV/c).
The results obtained from simulated events are compared to the existing data.
Sensitivity to the two photons exchange mechanism is also investigated.Comment: 12 pages, 4 tables, 8 figures Revised, added details on simulations,
4 tables, 9 figure
Technical Design Report for the PANDA Solenoid and Dipole Spectrometer Magnets
This document is the Technical Design Report covering the two large
spectrometer magnets of the PANDA detector set-up. It shows the conceptual
design of the magnets and their anticipated performance. It precedes the tender
and procurement of the magnets and, hence, is subject to possible modifications
arising during this process.Comment: 10 pages, 14MB, accepted by FAIR STI in May 2009, editors: Inti
Lehmann (chair), Andrea Bersani, Yuri Lobanov, Jost Luehning, Jerzy Smyrski,
Technical Coordiantor: Lars Schmitt, Bernd Lewandowski (deputy),
Spokespersons: Ulrich Wiedner, Paola Gianotti (deputy
Feasibility studies of time-like proton electromagnetic form factors at PANDA at FAIR
Simulation results for future measurements of electromagnetic proton form
factors at \PANDA (FAIR) within the PandaRoot software framework are reported.
The statistical precision with which the proton form factors can be determined
is estimated. The signal channel is studied on the basis
of two different but consistent procedures. The suppression of the main
background channel, , is studied.
Furthermore, the background versus signal efficiency, statistical and
systematical uncertainties on the extracted proton form factors are evaluated
using two different procedures. The results are consistent with those of a
previous simulation study using an older, simplified framework. However, a
slightly better precision is achieved in the PandaRoot study in a large range
of momentum transfer, assuming the nominal beam conditions and detector
performance
Human Glycolipid Transfer Protein (GLTP) Expression Modulates Cell Shape
Glycolipid transfer protein (GLTP) accelerates glycosphingolipid (GSL) intermembrane transfer via a unique lipid transfer/binding fold (GLTP-fold) that defines the GLTP superfamily and is the prototype for GLTP-like domains in larger proteins, i.e. phosphoinositol 4-phosphate adaptor protein-2 (FAPP2). Although GLTP-folds are known to play roles in the nonvesicular intracellular trafficking of glycolipids, their ability to alter cell phenotype remains unexplored. In the present study, overexpression of human glycolipid transfer protein (GLTP) was found to dramatically alter cell phenotype, with cells becoming round between 24 and 48 h after transfection. By 48 h post transfection, ∼70% conversion to the markedly round shape was evident in HeLa and HEK-293 cells, but not in A549 cells. In contrast, overexpression of W96A-GLTP, a liganding-site point mutant with abrogated ability to transfer glycolipid, did not alter cell shape. The round adherent cells exhibited diminished motility in wound healing assays and an inability to endocytose cholera toxin but remained viable and showed little increase in apoptosis as assessed by poly(ADP-ribose) polymerase cleavage. A round cell phenotype also was induced by overexpression of FAPP2, which binds/transfers glycolipid via its C-terminal GLTP-like fold, but not by a plant GLTP ortholog (ACD11), which is incapable of glycolipid binding/transfer. Screening for human protein partners of GLTP by yeast two hybrid screening and by immuno-pulldown analyses revealed regulation of the GLTP-induced cell rounding response by interaction with δ-catenin. Remarkably, while δ-catenin overexpression alone induced dendritic outgrowths, coexpression of GLTP along with δ-catenin accelerated transition to the rounded phenotype. The findings represent the first known phenotypic changes triggered by GLTP overexpression and regulated by direct interaction with a p120-catenin protein family member
Thermal Dileptons at LHC
We predict dilepton invariant-mass spectra for central 5.5 ATeV Pb-Pb
collisions at LHC. Hadronic emission in the low-mass region is calculated using
in-medium spectral functions of light vector mesons within hadronic many-body
theory. In the intermediate-mass region thermal radiation from the Quark-Gluon
Plasma, evaluated perturbatively with hard-thermal loop corrections, takes
over. An important source over the entire mass range are decays of correlated
open-charm hadrons, rendering the nuclear modification of charm and bottom
spectra a critical ingredient.Comment: 2 pages, 2 figures, contributed to Workshop on Heavy Ion Collisions
at the LHC: Last Call for Predictions, Geneva, Switzerland, 14 May - 8 Jun
2007 v2: acknowledgment include
Multiplicity dependence of jet-like two-particle correlations in p-Pb collisions at = 5.02 TeV
Two-particle angular correlations between unidentified charged trigger and
associated particles are measured by the ALICE detector in p-Pb collisions at a
nucleon-nucleon centre-of-mass energy of 5.02 TeV. The transverse-momentum
range 0.7 5.0 GeV/ is examined,
to include correlations induced by jets originating from low
momen\-tum-transfer scatterings (minijets). The correlations expressed as
associated yield per trigger particle are obtained in the pseudorapidity range
. The near-side long-range pseudorapidity correlations observed in
high-multiplicity p-Pb collisions are subtracted from both near-side
short-range and away-side correlations in order to remove the non-jet-like
components. The yields in the jet-like peaks are found to be invariant with
event multiplicity with the exception of events with low multiplicity. This
invariance is consistent with the particles being produced via the incoherent
fragmentation of multiple parton--parton scatterings, while the yield related
to the previously observed ridge structures is not jet-related. The number of
uncorrelated sources of particle production is found to increase linearly with
multiplicity, suggesting no saturation of the number of multi-parton
interactions even in the highest multiplicity p-Pb collisions. Further, the
number scales in the intermediate multiplicity region with the number of binary
nucleon-nucleon collisions estimated with a Glauber Monte-Carlo simulation.Comment: 23 pages, 6 captioned figures, 1 table, authors from page 17,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/161
Charge separation relative to the reaction plane in Pb-Pb collisions at TeV
Measurements of charge dependent azimuthal correlations with the ALICE
detector at the LHC are reported for Pb-Pb collisions at TeV. Two- and three-particle charge-dependent azimuthal correlations in
the pseudo-rapidity range are presented as a function of the
collision centrality, particle separation in pseudo-rapidity, and transverse
momentum. A clear signal compatible with a charge-dependent separation relative
to the reaction plane is observed, which shows little or no collision energy
dependence when compared to measurements at RHIC energies. This provides a new
insight for understanding the nature of the charge dependent azimuthal
correlations observed at RHIC and LHC energies.Comment: 12 pages, 3 captioned figures, authors from page 2 to 6, published
version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/286
- …