221 research outputs found
Differential IL-1β secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability.
- Author
- A MacKenzie
- A Piccini
- AA Sharma
- AM Knapinska
- AM Zawada
- B Passlick
- C Antonopoulos
- CA Dinarello
- D Kontoyiannis
- D Perregaux
- DJ Stumpo
- E Carballo
- E Shantsila
- E Vigano
- E Wang
- F Martinon
- G Buell
- G Laroia
- G Shaw
- GM Wilson
- IA Vlasova
- J Cros
- J Maelfait
- JA Hagar
- JH Edwan
- JR Ward
- JY Lu
- JY Lu
- KL Wong
- KL Wong
- KS Sinsimer
- L Ziegler-Heitbrock
- M Alfaidi
- ME Edye
- MG Netea
- N Kayagaki
- N Marina-Garcia
- N Sadri
- P Ancuta
- P Ivanov
- P Pelegrin
- P Pelegrin
- P Pelegrin
- RA Black
- RG Snodgrass
- SD Wright
- T Kastelic
- T Takenouchi
- T Takenouchi
- VA Rathinam
- WP Arend
- Y Qu
- YL Chen
- ZJ Shen
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/12/2016
- Field of study
Monocytes play a central role in regulating inflammation in response to infection or injury, and during auto-inflammatory diseases. Human blood contains classical, intermediate and non-classical monocyte subsets that each express characteristic patterns of cell surface CD16 and CD14; each subset also has specific functional properties, but the mechanisms underlying many of their distinctive features are undefined. Of particular interest is how monocyte subsets regulate secretion of the apical pro-inflammatory cytokine IL-1β, which is central to the initiation of immune responses but is also implicated in the pathology of various auto-immune/auto-inflammatory conditions. Here we show that primary human non-classical monocytes, exposed to LPS or LPS + BzATP (3'-O-(4-benzoyl)benzyl-ATP, a P2X7R agonist), produce approx. 80% less IL-1β than intermediate or classical monocytes. Despite their low CD14 expression, LPS-sensing, caspase-1 activation and P2X7R activity were comparable in non-classical monocytes to other subsets: their diminished ability to produce IL-1β instead arose from 50% increased IL-1β mRNA decay rates, mediated by Hsp27. These findings identify the Hsp27 pathway as a novel therapeutic target for the management of conditions featuring dysregulated IL-1β production, and represent an advancement in understanding of both physiological inflammatory responses and the pathogenesis of inflammatory diseases involving monocyte-derived IL-1β
The cytoskeleton in cell-autonomous immunity: structural determinants of host defence
- Author
- A Ablasser
- A Akhter
- A Desai
- A Fukazawa
- A Stolz
- AB Jaffe
- AF Frade
- AJ Thrasher
- AL Waite
- AM Keestra
- AP West
- AR Shenoy
- Avinash R. Shenoy
- B Levine
- B-H Kim
- BB Mishra
- BT Kile
- C Stevens
- C Watts
- CM Haglund
- CS Weirich
- D Chen
- D Ghosal
- D Parker
- D Sancho
- DC Rubinsztein
- DJ Philpott
- DL Clemens
- DM Underhill
- E Bi
- E Caron
- EL Benanti
- F Caudron
- F Martinon
- F Randow
- F Randow
- F Rees
- G Bonizzi
- G dos Santos
- G Kuhlenbaumer
- G Tran Van Nhieu
- H Bielig
- H Herrmann
- H Sridharan
- H Xu
- HB Yu
- HS Goodridge
- I Monastyrska
- IM Dambuza
- J Eitel
- J Huang
- J Jin
- J Li
- J Li
- J Pizarro-Cerdá
- J Saarikangas
- J Shi
- J von Moltke
- J-G Zhang
- JA Hagar
- JA Swanson
- JC Kagan
- JCH Tam
- JD MacMicking
- JJ Bravo-Cordero
- JL Dangl
- JP Solomon
- JR Terman
- JS Hyams
- JSC Arthur
- JW Jones
- K Aktories
- K Aktories
- K Dobbs
- K Gotoh
- KL Angus
- L Blanchoin
- L Kong
- L Le Bourhis
- LA Cameron
- LA Knodler
- LJF Jones
- M Kokes
- M Lamkanfi
- M Ogawa
- M Ogawa
- M Pasparakis
- M Rosas
- M Sasai
- M Yoneyama
- MA Al-Zeer
- MA Gavrilin
- MA Gavrilin
- MA Gavrilin
- MA Sanjuan
- MB Torchinsky
- MD Welch
- MJG Eldridge
- ML Kim
- MT Cabeen
- N Ausmees
- N Carayol
- N Kayagaki
- N Kayagaki
- N Mizushima
- N Ostler
- N Schroeder
- N Subramanian
- NE Harwood
- NT Snider
- P Cossart
- P Hanc
- P Wild
- P Xia
- PS Manzanillo
- R Goldbach-Mansky
- R Mackeh
- R Muñoz-Planillo
- RC Wang
- RE Vance
- S Ahrens
- S Asrat
- S Iborra
- S Legrand-Poels
- S Mostowy
- S Mostowy
- S Mostowy
- S Mostowy
- S Mostowy
- S Mostowy
- S Mostowy
- S Mostowy
- S Park
- S Savic
- S Zelenay
- SA Schattgen
- SCO Reed
- Serge Mostowy
- SL Sandiford
- SM Man
- T Fernandes-Alnemri
- T Kawai
- T Misawa
- T Strowig
- T Tamura
- TA Kufer
- TD Pollard
- TLM Thurston
- U Golebiewska
- V Deretic
- VAK Rathinam
- VAK Rathinam
- W-D Hardt
- WA McEwan
- WM Schneider
- X Cai
- Y Aachoui
- Y Aachoui
- Y Kumar
- Y Ma
- Y Song
- Y Tanaka-Takiguchi
- Y Yoshikawa
- Y Zhao
- Y-W Huang
- YT Zheng
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 21/08/2015
- Field of study
Host cells use antimicrobial proteins, pathogen-restrictive compartmentalization and cell death in their defence against intracellular pathogens. Recent work has revealed that four components of the cytoskeleton — actin, microtubules, intermediate filaments and septins, which are well known for their roles in cell division, shape and movement — have important functions in innate immunity and cellular self-defence. Investigations using cellular and animal models have shown that these cytoskeletal proteins are crucial for sensing bacteria and for mobilizing effector mechanisms to eliminate them. In this Review, we highlight the emerging roles of the cytoskeleton as a structural determinant of cell-autonomous host defence
Clinical validation of cutoff target ranges in newborn screening of metabolic disorders by tandem mass spectrometry: a worldwide collaborative project.
- Author
- Å
- Abdenur Je
- Abdulrahman M
- Adair O
- Al Nuaimi SA
- Allen Jj
- Antonozzi I
- Archer S
- Au S
- Auray Blais C
- Baker M
- Bamforth F
- Beckmann K
- Berberich Sl
- Bermejo Ms
- Binard R
- Boemer F
- Bonham J
- Breen Nn
- Bryant Sc
- Bryant Sc
- Caggana M
- Caggana M
- Caldwell Sg
- Caldwell Sg
- Cameron Ca
- Camilot M
- Camilot M
- Campbell C
- Campbell C
- Carducci C
- Carducci C
- Cariappa R
- Carlisle C
- Caruso U
- Cassanello M
- Castilla Am
- Chakraborty P
- Chandrasekar R
- Cheillan D
- Chien Yh
- Childs Ta
- Chrastina P
- Colandre Me
- Corso G
- Currier R
- Cyr D
- Czuczy N
- D&apos
- Davis T
- de Juan JA
- de Sain Van der Velden MG
- Delgado Pecellin C
- Di Gangi IM
- Di Stefano CM
- Domingos Mt
- Dotsikas Y
- Downing M
- Downs Sm
- Dy B
- Dymerski M
- Eaton R
- Eckerd Bm
- El Mougy F
- Elvers B
- Eroh S
- Espada M
- Espinoza Vc
- Evans C
- Fawbush S
- Fijolek Kf
- Fisher L
- Franzson L
- Frazier Dm
- Garcí
- Garcia Lr
- Gavrilov D
- Gerace R
- Giordano G
- Greed Lc
- Greenberg Cr
- Grier R
- Grycki E
- Gu X
- Gulamali Majid F
- Hadachi Sm
- Hagar Af
- Han L
- Hannon Wh
- Haslip C
- Hassan Fa
- He M
- Hietala A
- Himstedt L
- Hoffman Gl
- Hoffman W
- Hoggatt P
- Hopkins Pv
- Hougaard Dm
- Hughes K
- Hunt Pr
- Hwu Wl
- Hynes J
- Ibarra Gonzá
- Ingham Ca
- Irazabal Yg
- Ivanova M
- Jó
- Jacox Wb
- John C
- Johnson Jp
- Jones Al
- Juan Fita MJ
- Karg E
- Kasper D
- Katakouzinos D
- Khneisser I
- Klopper B
- Knoll D
- Kobayashi H
- Kohlmueller D
- Koneski R
- Kouapei R
- Kozich V
- Kremensky I
- La Marca Giancarlo
- Lavochkin M
- Lee Sy
- Lehotay Dc
- Lemes A
- Lepage J
- Lesko B
- Lewis B
- Lim C
- Linard S
- Lindner M
- Lloyd Puryear MA
- Lorey F
- Loukas Yl
- Luedtke J
- Maffitt N
- Magee Jf
- Manning A
- Manos S
- Marie S
- Marquardt G
- Martin Sj
- Matern D
- Mayfield Gibson SK
- Mayne P
- McCallister Td
- McCann M
- McClure J
- McGill Jj
- McHugh Dm
- McKeever Cd
- McNeilly B
- Mellado Jm
- Morrissey Ma
- Moutsatsou P
- Mulcahy Ea
- Nikoloudis D
- Norgaard Pedersen B
- Oglesbee D
- Ojodu J
- Oltarzewski M
- Ombrone D
- Papakonstantinou V
- Park Hd
- Pasquali M
- Pasquini E
- Pass Ka
- Patel P
- Peterson C
- Pettersen Rd
- Pino Gb
- Pitt Jj
- Poh S
- Pollak A
- Porter C
- Poston Pa
- Price Rw
- Queijo C
- Quesada J
- Ramos Ac
- Ramos De
- Randell E
- Ranieri E
- Raymond K
- Reddic Je
- Reoyo Sp
- Reuben A
- Ricciardi C
- Rinaldo P
- Rivera Jd
- Roberts A
- Rocha H
- Roche G
- Rueda I
- Ruiz C
- Ruoppolo M
- Rutledge Sl
- Ryu E
- Saban C
- Sahai I
- Santiago Borrero P
- Schenone A
- Schoos R
- Schweitzer B
- Scott P
- Seashore Mr
- Seeterlin Ma
- Sesser De
- Sevier Dw
- Shone Sm
- Sica Yc
- Sinclair G
- Skrinska Va
- Stanley El
- Strovel Et
- Sunny S
- Takats Z
- Tanyalcin T
- Teofoli F
- Thompson Jr
- Tomashitis K
- Torres J
- Torres R
- Tortorelli S
- Turi S
- Turner K
- Tzanakos N
- Valiente Ag
- Vallance H
- Vela Amieva M
- Vilarinho L
- Vincent Mf
- von Dö
- Vorster Bc
- Watson Ms
- Webster D
- Weiss S
- Wilcken B
- Wiley V
- Williams Sk
- Willis Sa
- Woontner M
- Wright K
- Yahyaoui R
- Yamaguchi S
- Yssel M
- Zakowicz W. M.
- Publication venue
- Publication date
- 01/01/2011
- Field of study
Chagas heart disease: pathophysiologic mechanisms, prognostic factors and risk stratification
- Author
- Amorim DS
- Andrade SG
- Andrade ZA
- Anis Rassi
- Anis Rassi Jr
- Benchimol Barbosa PR
- Bestetti RB
- Bestetti RB
- Bonney KM
- Bustamante JM
- Carrasco HA
- Chagas C
- Coura JR
- Dias JC
- Dutra WO
- Espinosa RA
- Fabbro DL
- Garcia S
- Garzon SAC
- Gonçalves JG
- Hagar JM
- Higuchi ML
- José Antonio Marin-Neto
- Kierszenbaum F
- Köberle F
- Leite LR
- Mady C
- Marin-Neto JA
- Marin-Neto JA
- Marin-Neto JA
- Matturri L
- Nunes MC
- Nunes MC
- Rassi A
- Rassi A Jr
- Rassi A Jr
- Rassi A Jr
- Rassi A Jr
- Remme JHF
- Ribeiro AL
- Ribeiro AL
- Rodriguez-Salas LA
- Rossi MA
- Rossi MA
- Salles G
- Sartori AM
- Schmunis GA
- Simões MV
- Storino R
- Tarleton RL
- Tarleton RL
- Tarleton RL
- Theodoropoulos TA
- Torres FW
- Viotti RJ
- Viotti RJ
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
On the mechanisms governing gas penetration into a tokamak plasma during a massive gas injection
- Author
- Abhangi M.
- Abreu P.
- Aftanas M.
- Afzal M.
- Aggarwal K.M.
- Aho-Mantila L.
- Ahonen E.
- Aints M.
- Airila M.
- Albanese R.
- Alegre D.
- Alessi E.
- Aleynikov P.
- Alfier A.
- Alkseev A.
- Allan P.
- Almaviva S.
- Alonso A.
- Alper B.
- Alsworth I.
- Alves D.
- Ambrosino G.
- Ambrosino R.
- Amosov V.
- Andersson Sunde´n E.
- Andersson F.
- Angelone M.
- Anghel A.
- Anghel M.
- Angioni C.
- Appel L.
- Apruzzese G.
- Arena P.
- Ariola M.
- Arnichand H.
- Arnoux G.
- Arshad S.
- Asakura N.N.
- Ash A.
- Asp E.
- Asunta O.
- Atanasiu C.V.
- Austin Y.
- Avotina L.
- Axton M.D.
- Ayres C.
- Bachmann C.
- Baciero A.
- Baia˜o D.
- Bailescu V.
- Baiocchi B.
- Baker A.
- Baker R.A.
- Balboa I.
- Balden M.
- Balshaw N.
- Bament R.
- Banks J.W.
- Baranov Y.F.
- Barlow I.L.
- Barnard M.A.
- Barnes D.
- Barnsley R.
- Baron Wiechec A.
- Baruzzo M.
- Basiuk V.
- Bassan M.
- Bastow R.
- Batista A.
- Batistoni P.
- Bauer R.
- Bauvir B.
- Bazylev B.
- Beal J.
- Beaumont P.S.
- Becoulet A.
- Bednarczyk P.
- Bekris N.
- Beldishevski M.
- Bell K.
- Belli F.
- Bellinger M.
- Belo J.K.
- Belo P.
- Belonohy E´.
- Benterman N.A.
- Bergsåker H.
- Bernardo J.
- Bernert M.
- Berry M.
- Bertalot L.
- Beurskens M.N.A.
- Bieg B.
- Bielecki J.
- Biewer T.
- Bigi M.
- Binda F.
- Bizarro J.P.S.
- Bjo¨ rkas C.
- Blackman K.
- Blackman T.R.
- Blanchard P.
- Blanco E.
- Blatchford P.
- Bobkov V.
- Boboc A.
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- Bogar O.
- Bolzonella T.
- Boncagni L.
- Bonham R.
- Bonheure G.
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- Borodin D.
- Botrugno A.
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- Bovert K.V.
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- Buch J.
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- Cocilovo V.
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- Formisano A.
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- Heesterman P.J.L.
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- Hellesen C.
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- Hunter C.L.
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- Imr´ısˇek M.
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- Ivanova- Stanik I.
- Ivings E.
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- Kalupin D.
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- Publication venue
- 'IOP Publishing'
- Publication date
- 09/11/2016
- Field of study
A new 1D radial fluid code, IMAGINE, is used to simulate the penetration of gas into a tokamak plasma during a massive gas injection (MGI). The main result is that the gas is in general strongly braked as it reaches the plasma, due to mechanisms related to charge exchange and (to a smaller extent) recombination. As a result, only a fraction of the gas penetrates into the plasma. Also, a shock wave is created in the gas which propagates away from the plasma, braking and compressing the incoming gas. Simulation results are quantitatively consistent, at least in terms of orders of magnitude, with experimental data for a D 2 MGI into a JET Ohmic plasma. Simulations of MGI into the background plasma surrounding a runaway electron beam show that if the background electron density is too high, the gas may not penetrate, suggesting a possible explanation for the recent results of Reux et al in JET (2015 Nucl. Fusion 55 093013)
Laparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study.
- Author
- Abantanga F
- Abbas M
- Abbo O
- Abd El Galeel A
- Abd El Hameed OS
- Abd El Hamid N
- Abd El Salam Y
- Abd El Slam M
- Abd El-Salam F
- Abd Elrasoul Y
- Abd-Elrasoul Y
- Abdallah E
- Abdel-Wahab NYE
- AbdelFattah I
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- Abdelkareem A
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- Abdulgawad M
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- Yaseen TM
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- Youssef H
- Youssif JH
- Zachariades D-C
- Zakir M
- Zalabia MF
- Zamarin K
- Zani A
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- Zapata Ponze De Leon M
- Zapata Ponze De Leon M
- Zardab A
- Zegarra S
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- Zelada Alvarez II
- Zerihun AB
- Zhang Z
- Zheng F
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- Zimmermann EF
- Zuber M
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
BACKGROUND: Appendicitis is the most common abdominal surgical emergency worldwide. Differences between high- and low-income settings in the availability of laparoscopic appendectomy, alternative management choices, and outcomes are poorly described. The aim was to identify variation in surgical management and outcomes of appendicitis within low-, middle-, and high-Human Development Index (HDI) countries worldwide. METHODS: This is a multicenter, international prospective cohort study. Consecutive sampling of patients undergoing emergency appendectomy over 6 months was conducted. Follow-up lasted 30 days. RESULTS: 4546 patients from 52 countries underwent appendectomy (2499 high-, 1540 middle-, and 507 low-HDI groups). Surgical site infection (SSI) rates were higher in low-HDI (OR 2.57, 95% CI 1.33-4.99, p = 0.005) but not middle-HDI countries (OR 1.38, 95% CI 0.76-2.52, p = 0.291), compared with high-HDI countries after adjustment. A laparoscopic approach was common in high-HDI countries (1693/2499, 67.7%), but infrequent in low-HDI (41/507, 8.1%) and middle-HDI (132/1540, 8.6%) groups. After accounting for case-mix, laparoscopy was still associated with fewer overall complications (OR 0.55, 95% CI 0.42-0.71, p < 0.001) and SSIs (OR 0.22, 95% CI 0.14-0.33, p < 0.001). In propensity-score matched groups within low-/middle-HDI countries, laparoscopy was still associated with fewer overall complications (OR 0.23 95% CI 0.11-0.44) and SSI (OR 0.21 95% CI 0.09-0.45). CONCLUSION: A laparoscopic approach is associated with better outcomes and availability appears to differ by country HDI. Despite the profound clinical, operational, and financial barriers to its widespread introduction, laparoscopy could significantly improve outcomes for patients in low-resource environments. TRIAL REGISTRATION: NCT02179112
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
- Author
- A Aouacheria
- A Aouacheria
- A Aranovich
- A Ashkenazi
- A Ashkenazi
- A Ashkenazi
- A Bernet
- A Buque
- A Chiche
- A Conte
- A Costanzo
- A Crockford
- A Degterev
- A Degterev
- A Dey
- A Gast
- A Gross
- A Hakkim
- A Hamacher-Brady
- A Hunger
- A Kaczmarek
- A Kamb
- A Koenig
- A Kotschy
- A Letai
- A Linkermann
- A Linkermann
- A Linkermann
- A Linkermann
- A Mousa
- A Muir
- A Mukherjee
- A Nilsson
- A Oberst
- A Oberst
- A Pagotto
- A Pyakurel
- A Rongvaux
- A Rubartelli
- A Sahaboglu
- A Seiler
- A Serrano-Puebla
- A Shamas-Din
- A Sistigu
- A Strasser
- A Strasser
- A Strasser
- A Strasser
- A Strasser
- A Strasser
- A Sumoza-Toledo
- A Sundararaman
- A Tittarelli
- A Trautmann
- A Villunger
- A Witt
- A Zychlinsky
- AA Fatokun
- AA Mailleux
- Aaron Ciechanover
- AB Pardee
- Abhishek D. Garg
- AC Bellail
- AC Schinzel
- AD Garg
- AD Garg
- AD Garg
- AD Garg
- AD Garg
- AD Garg
- AD Garg
- Adi Kimchi
- AE Alsop
- AE Feldstein
- AJ Schile
- AL Anding
- AL Genevois
- Alexey V. Antonov
- AM Chinnaiyan
- AM Distefano
- AM Dudek
- AM Verhagen
- AN Antony
- AN Barclay
- Ana J. García-Sáez
- Andreas Linkermann
- Andreas Strasser
- Andreas Villunger
- Andrew Oberst
- Andrew Thorburn
- Antonella Sistigu
- AP West
- AR Delbridge
- AT Schneider
- AT Ting
- AT Ting
- Atan Gross
- AV Follis
- AV Jacobsen
- AV Vaseva
- AV Vaseva
- AW Roberts
- B Antonsson
- B Aslan
- B Conradt
- B Fadeel
- B Gerlach
- B Gibert
- B Gooptu
- B McDonald
- B Schellenberg
- B Van Do
- B Xia
- BA Carlson
- BA Hilton
- BA Napier
- BB Aggarwal
- BC Barnhart
- Bertrand Joseph
- Beth Levine
- BG Childs
- BG Childs
- BG Childs
- BG Lambrus
- BG Yipp
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- Valina L. Dawson
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- Vincenzo De Laurenzi
- Vincenzo D’Angiolella
- Vishva M. Dixit
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- Y Aachoui
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- Y Ito
- Y Lee
- Y Li
- Y Li
- Y Liu
- Y Liu
- Y Luo
- Y Ma
- Y Ma
- Y Morizane
- Y Ou
- Y Pang
- Y Rong
- Y Shlyakhtina
- Y Subburaj
- Y Suzuki
- Y Tsujimoto
- Y Wang
- Y Wang
- Y Wang
- Y Wang
- Y Xie
- Y Xie
- Y Xie
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- Y Zermati
- Y Zhang
- Y Zheng
- Y Zhu
- Y Zhu
- YB Chen
- YC Hou
- YH Liao
- YI Nakajima
- Ying Wang
- YN Gong
- Yoshihide Tsujimoto
- YS Cho
- Yufang Shi
- Z Cai
- Z Cai
- Z Wang
- Z Wang
- Z Xu
- Z You
- Z Zhang
- Z Zhong
- Zahra Zakeri
- ZG Liu
- ZN Oltvai
- ZT Schafer
- ZX Chen
- ZX Chen
- Publication venue
- Cell Death Differ
- Publication date
- 01/01/2018
- Field of study
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives. Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an updated classification of cell death subroutines focusing on mechanistic and essential (as opposed to correlative and dispensable) aspects of the process. As we provide molecularly oriented definitions of terms including intrinsic apoptosis, extrinsic apoptosis, mitochondrial permeability transition (MPT)-driven necrosis, necroptosis, ferroptosis, pyroptosis, parthanatos, entotic cell death, NETotic cell death, lysosome-dependent cell death, autophagy-dependent cell death, immunogenic cell death, cellular senescence, and mitotic catastrophe, we discuss the utility of neologisms that refer to highly specialized instances of these processes. The mission of the NCCD is to provide a widely accepted nomenclature on cell death in support of the continued development of the field
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
- Author
- Aahlin EK
- Aamer A
- Aaniana K
- Ababneh A
- Abaliksta T
- Abantanga F
- Abantanga F
- Abbas A
- Abbas M
- Abbasy J
- Abbo O
- Abbo O
- Abbott T
- Abbouch M
- Abd El Galeel A
- Abd El Hameed OS
- Abd El Hamid N
- Abd El Salam Y
- Abd El Slam M
- Abd El-Salam F
- Abd Elrasoul Y
- Abd-Elmawla M
- Abd-Elrasoul Y
- Abdallah E
- Abdallah E
- Abdel-Aty A
- Abdel-Hameed N
- Abdel-Kader SM
- Abdel-Wahab NYE
- Abdelaal A
- Abdelaty M
- Abdelazeam AR
- Abdelazim G
- Abdelaziz MA
- Abdelbadeai K
- Abdelfatah A
- AbdelFattah I
- Abdelgelil A
- Abdelghany S
- Abdelhady S
- Abdelhamed R
- Abdelhamid A
- Abdelhaq A
- Abdelkader M
- Abdelkader M
- Abdelkader O
- Abdelkareem A
- Abdelkhalek M
- Abdelmageed E
- Abdelmotaleb I
- Abdelraheim M
- Abdelraouf AM
- Abdelrouf DM
- Abdelshafy M
- Abdelshakour M
- Abdrabou AK
- Abdul-Latif S
- Abdulaziz H
- Abdulaziz M
- Abdulbagi O
- Abdulgawad M
- Abdulhakeem EM
- Abdullah AAN
- Abdullah MA
- Abdullah N
- Abdullah NAN
- Abdullah NAN
- Abdullahi L
- Abdurrazzaaq A
- Abebe NS
- Abebe NS
- Abem OE
- Aber A
- Abington E
- Abiola O
- Aboarab A
- Aboelella M
- Aboelmagd O
- Aboelsoud MR
- Aboraya M
- Aboraya M
- Abouelnasr A
- Aboul-Naga MS
- Abouzahra A
- Abouzaid A
- Abozaid M
- Abozeid K
- Abozyed MAF
- Abu Qumbos A
- Abu-toyour M
- Abubakr M
- Abudeeb H
- Abuowda Y
- Abuqwaider E
- Abusalem L
- Abuseif M
- Abushamleh S
- Acharya P
- Ackom E
- Acquah E
- Adam A
- Adam N
- Adams R
- Adamu A
- Adawi I
- Adawi M
- Adebanjo A
- Adebanjo A
- Adebola O
- Adedeji A
- Adekoya A
- Adel A
- Adel A
- Adel BE
- Adel I
- Adella FJ
- Adelshone A
- Ademuyiwa A
- Ademuyiwa A
- Ademuyiwa AO
- Ademuyiwa AO
- Ademuyiwa AO
- Ademuyiwa AO
- Adenekan B
- Adeniran J
- Adeniran J
- Adeniyi A
- Adeniyi A
- Adesanya O
- Adesanya O
- Adesina A
- Adesina A
- Adesuyi A
- Adeyeye A
- Adeyeye A
- Adeyeye A
- Adham W
- Adhitama N
- Adil M
- Adisa AO
- Adisa AO
- Adu-Aryee N
- Afana S
- Afandy A
- Afifi AM
- Afzal M
- Agalianos C
- Agalianos C
- Agarwal A
- Agarwal A
- Agarwal A
- Agbedinu K
- Agius M
- Aglan A
- Aguado Suarez N
- Aguilar-Jimenez J
- Aguilera M
- Aguilera ML
- Aguilera ML
- Aguilera ML
- Aguilera O
- Aguilera-Arevalo M-L
- Ahlonsou G
- Ahlqvist S
- Ahlqvist S
- Ahlqvist S
- Ahmed A
- Ahmed A
- Ahmed A
- Ahmed EA
- Ahmed H
- Ahmed H
- Ahmed H
- Ahmed LAM
- Ahmed S
- Ahmed S
- Ahmed SM
- Ahounou EYS
- Aigrain Y
- Aiyaman C
- Ajah J
- Ajai O
- Ajao A
- Ajao AE
- Ajiboye A
- Akatibo E
- Akeel N
- Akhtar M
- Akoto E
- Akpenyi O
- Al Amin S
- Al Attar SM
- Al Awwad S
- Al Barrawi FE
- Al Bastawis F
- Al Meligy A
- Al Rafati AAR
- Al Raouf EA
- Al Saied G
- Al Subaie N
- Al-Aarag AA-R
- Al-Azraqi IAA
- Al-Bahrani A
- Al-Buhaisi A
- Al-Dakka E
- Al-Faifi JJ
- Al-faqawi M
- Al-farram H
- Al-Hameedi HII
- Al-Hasani RKMJ
- Al-khatib A
- Al-Mallah A
- Al-Marakby D
- Al-Mousa M
- Al-Nahrawi S
- Al-Obaedi O
- Al-saqqa S
- Al-Saqqa SW
- Al-Saqqa SW
- Al-shammari A
- Al-Slaibi I
- Al-taher T
- Alaael-Dein S
- Alada M
- Alahmady O
- Alakaloko F
- Alakaloko F
- Alaloul E
- Alamin S
- Alamoudi M
- Alamoudi U
- Albeladi B
- Albiety A
- Alcca Ticona W
- Aldalaq A
- Aldhafeeri S
- Aledrisy M
- Alejos Bermudez YE
- Alexander P
- Alexander P
- Alexander P
- Alexandre C
- Alfarsi MA
- Alghamdi A
- Alghamdi B
- Alghamdi M
- Alghamdi MSA
- Algohary O
- Alhabli I
- Alhady K
- Alhammali T
- Alhassan B
- Alhazmi W
- Alhendy M
- Alherz M
- Ali A
- Ali A
- Ali A
- Ali CDM
- Ali E
- Ali FM
- Ali H
- Ali S
- Ali SAWEW
- Ali SS
- Ali THA
- Ali W
- Alihonou T
- Alimi Q
- Alis H
- Aliyu H
- Aliyu M
- Aliyu S
- Aljboor K
- Aljiffry M
- Aljiffry M
- Aljohani E
- Aljohani E
- Aljohani S
- Alkaaki A
- Alkammash A
- Alkelani M
- Alkhabbaz D
- Alkhouri M
- Allam M
- Allam M
- Allam Y
- Allegri A
- Allegri A
- Allen JLY
- Allott R
- Almallah A
- Almoflihi A
- Almuallem S
- Almy J
- Alnaby MH
- Alnawam E
- Alnuqaydan SA
- Alnusairat A
- Alomar IN
- Alqahtani E
- Alqahtani S
- Alrahawy M
- Alrajraji M
- Alrifaie A
- AlRowais M
- Alsaggaf M
- Alsaggaf MU
- Alsaggaf MU
- Alser OH
- Alshareef R
- Altaf A
- Altaf A
- Altamimi A
- Altamimi A
- Altamimi A
- Altamimi A
- Altamini A
- Altarayra M
- Althwainy A
- Altibi A
- Altinel Y
- Altinel Y
- Altoe F
- Altwigry AM
- Altwijri A
- Alvarado Jaramillo R
- Alvarez Barreda LM
- Alvi AR
- Alwafai MG
- Aly AK
- Aly MYM
- Alyacoubi S
- Alyahya R
- Alyami R
- Alyami R
- AlYoussef I
- Alzahrani A
- Alzahrani M
- Alzahrani M
- Alzayat T
- Aman NF
- Amandito R
- Amandito R
- Amandito R
- Amandito R
- Ambrona-Zafra D
- Ambrozeviciute V
- Ameen M
- Amer MA
- Amin HAA
- Amin J
- Amin J
- Amjad M
- Ammar M
- Ammar MS
- Amoah M
- Amoako J
- Amoako PT
- Amoako-Boateng M
- Amole I
- Amreia M
- Amreia M
- Anandkumar D
- Anderson D
- Anderson F
- Anderson R
- Anderson-Knight H
- Andersson L
- Andika FFA
- Andreotti D
- Andres Garcia-Marin J
- Andress C
- Andriola V
- Ang YL
- Angelieri D
- Anis E
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Antar S
- Antezana D
- Anthoulakis C
- Anthoulakis C
- Antoniozzi A
- Anwar AW
- Anwar N
- Anwer W
- Anyanwu L-J
- Anyanwu L-J
- Aonzo P
- Appeadu-Mensah W
- Appiah EK
- Aql S
- Aquilino F
- Arachchi PP
- Arachchige LAJJ
- Arafa O
- Arafa S
- Arango MCM
- Arango MCM
- Aranzabal Durand SY
- Araujo R
- Arcudi C
- Ardley R
- Arenas A
- Arevalo Azmitia JR
- Arias Pacheco RD
- Arman S
- Arman S
- Armando ChunguiBravo J
- Armellini A
- Arnaud A
- Arnaud AP
- Arnaud AP
- Arnaud AP
- Arroyo Basto CA
- Arshad MM
- Arslan E
- Arsyad HM
- Arthur T
- Arulampalam T
- Aruldas N
- Asal M
- Asar YH
- Asare-Bediako K
- Asele FA
- Ashour A
- Ashour A
- Ashour K
- Ashraf SF
- Ashtari M
- Ashton A
- Asi F
- Asilah SMD
- Assal A
- Assouto PA
- Asturia S
- Asumah H
- Ata A
- Ata AAA
- Ata AY
- Atiyeh A
- Atkins ET
- Atkinson K
- Atobatele K
- Attallah NA
- Attard M
- Attia A
- Attia AM
- Augestad KM
- Aung KP
- Austraite A
- Aviles S
- Avoka A
- Awad I
- Awad SA
- Awadallah S
- Awuku-Asabre J
- Ayad S
- Ayandipo O
- Ayandipo OO
- Aydin MC
- Ayyar S
- Aziz DNA
- Aziz MRA
- Aziz NA
- Azizeldine MG
- Azmitia Mendizabal CA
- Azodo IA
- Azzie G
- Azzie G
- Azzis O
- Baba S
- Bachri H
- Badawy M
- Badenjki MA
- Badicel M
- Badr A
- Badr MFM
- Badwi NM
- Badwi NM
- Badwy A
- Bahar S
- Baheeg M
- Bailey K
- Baillie K
- Baillie K
- Baird A
- Bakhaidar M
- Baki BE
- Bakr A
- Bakry HM
- Bala M
- Balalis D
- Baldacchino M
- Balducci G
- Balila RMH
- Balkan AZA
- Ballouhey Q
- Balmaceda R
- Balmaceda R
- Balmaceda R
- Balogun F
- Baltrunas R
- Baluch F
- Bamford R
- Bamicha A
- Bamicha A
- Banaitis VJ
- Bandi A
- Bandoh D
- Bani-Sadar A
- Banipal GS
- Baraka H
- Barakat SAE
- Barendegere V
- Barker T
- Barkolias C
- Barmayehvar B
- Barnabas GN
- Barnacle J
- Barneo L
- Barrionuevo Ojeda RR
- Barrios E
- Barrios E
- Barros De Castro Segundo LC
- Barroso de Lima CV
- Barry J
- Basilico S
- Basir ERM
- Bassem M
- Bassit KA
- Basso SMM
- Basson S
- Batt J
- Bayram S
- Beamon M
- Beasley W
- Beaton C
- Bedada AG
- Bediako-Bowan A
- Behar N
- Beisa V
- Beisa V
- Bekhet AH
- Bekhet NM
- Beleno AEM
- Belkouchi A
- Belli A
- Bello B
- Benammi S
- Benevento A
- Benevento A
- Benger M
- Bennai RM
- Benons N
- Bentounsi Z
- Benyaiche C
- Berti S
- Bertuello I
- Beuran M
- Beuran M
- Beyene R
- Bezerra Morais PA
- Bezzina M
- Bhang A
- Bhangu A
- Bhangu A
- Bhargava A
- Bharj IS
- Bhat S
- Bhatnagar A
- Bhattacharya S
- Bhopal KF
- Bhopal KF
- Bianco F
- Bigaran A
- Billy M
- Bin Adnan A
- Bin Hasnan M
- Bin Ismail MJ
- Bin Mahamood A
- Birindelli A
- Birring A
- Bisset C
- Bjorklund I
- Bjorklund I
- Blacker S
- Blackwell J
- Blanco R
- Blanco-Colino R
- Blencowe N
- Blencowe N
- Bliksoen M
- Blower E
- Bluelle R
- Blundell R
- Boakye-Yiadom K
- Boal M
- Bocchetti T
- Boddy A
- Bode C
- Bode C
- Bodur S
- Boereboom C
- Boggon A
- Boijsen M
- Bokhari S
- Bonavia K
- Bonavina L
- Bonavina L
- Bond-Smith G
- Bondin J
- Bondurri A
- Bondurri A
- Boni S
- Bonnard A
- Bonney W
- Borda Luque G
- Borda-Luque G
- Borda-Luque G
- Borg E
- Borg E
- Borg E
- Borin E
- Bortolasi L
- Bortolasi L
- Boshnaq M
- Botes S
- Bottini C
- Botto N
- Bouali O
- Bougard H
- Boukhal K
- Bowabsak A
- Bowe R
- Bowley D
- Bowling K
- Bowman C
- Boyce T
- Bradulskis S
- Bradulskis S
- Bratu M
- Bratu MR
- Bratu R-M
- Braungart S
- Bray LD
- Breaud J
- Breistrand M
- Breitenstein S
- Breslin R
- Brincat SD
- Broch A
- Brogden T
- Brown D
- Brown E
- Brown J
- Brown J
- Browning DRL
- Brunoni B
- Bsisu I
- Bucci L
- Bugaev N
- Bugeja R
- Buisson P
- Bukari M
- Bunting D
- Burger S
- Burmistrovas A
- Burns H
- Bustangi N
- Butt MT
- Cabala Chiong JA
- Cabala Chiong JA
- Cacurri A
- Cadogan DD
- Cahill R
- Cakaloglu HC
- Caliman C
- Callan R
- Camacho R
- Cameron B
- Camilleri GM
- Camilleri-Brennan J
- Camilleri-Brennan J
- Camilleri-Brennan JF
- Camilo Correa J
- Campagnaro T
- Canta Calua A
- Capito C
- Capleton P
- Carabott K
- Careta MC
- Carlucci M
- Carmela Lapitan M
- Carmona JM
- Carpio J
- Carrasco N
- Carreira J-A
- Carreiro De Freitas AV
- Cassar K
- Castro Mollo M
- Catani M
- Cautiero R
- Caydiid H
- Cecilia T
- Celik S
- Cengiz TB
- Cengiz Y
- Cengiz Y
- Cengiz Y
- Cengiz Y
- Ceriani C
- Cevik M
- Chabok A
- Chachulski W
- Chai C-A
- Chai FY
- Chambers A
- Chambers A
- Chan E
- Chan L
- Chan T-YK
- Chan XW
- Chan Z
- Chandrakumar C
- Chang K
- Chang KY-C
- Chapman A
- Chapman SJ
- Charles A
- Cheah AEZ
- Chen CY
- Chen KY
- Chen T-L
- Chenn R
- Cheong YJ
- Chetta N
- Cheung YHE
- Chew LS
- Chhabra S
- Chibuye C
- Chidambaram S
- Chiesa D
- Chilton G
- Chin PX
- Chin YR
- Chiu S
- Chiu S
- Chiu SMY
- Choi J
- Choi P
- Chong BFHK
- Chong CL
- Chong CL
- Chong CL
- Chong CS
- Chong H-Y
- Chong HY
- Choudhry A
- Chow CYN
- Chowdhury A
- Chowdhury D
- Chu K
- Chun A
- Chun T
- Chung KJ
- Chung S
- Ciccioli E
- Cirocchi R
- Ciubotaru C
- Claire R
- Clarissa A
- Clark DJ
- Clark T
- Clegg-Lampety J-N
- Clegg-Lamptey J-N
- Clement KD
- Clements JM
- Clerico G
- Clifford C
- Cloro LM
- Coasaca Huaraya R
- Coccolini F
- Coccolini F
- Coccolini F
- Coccolini F
- Cocker DM
- Cocorullo G
- Cohen DM
- Cohen F
- Cole S
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- Coletti M
- Colombani J-F
- Cona C
- Conci S
- Confalonieri G
- Conlon KC
- Connor K
- Connor K
- Contreras Merida SM
- Contreras Urquizu M
- Contreras Vergara AL
- Contreras E
- Coomber R
- Coompson CL
- Corbellini C
- Corbellino M
- Cornick J
- Coronel J
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- Corro-Diaz S
- Costa C
- Costa-Maia J
- Costa-Maia J
- Costas-Chavarri A
- Costas-Chavarri A
- Courboin E
- Court E
- Cox D
- Cox M
- Coyoy-Gaitan O
- Cragg J
- Craus-Miguel A
- Cross K
- Cruz DH
- Cruz H
- Cucumazzo S
- Cullen F
- Curletti G
- Currow C
- Currow C
- D'aguzan N
- D'Amours S
- D'amours SK
- D'cruz R
- D'Souza MS
- D'Souza R
- Da Silva LA
- Dabboor M
- Dabbour K
- Dabessa D
- Dablouk M
- Dablouk MO
- Dagoe E
- Dahy A
- Dainius E
- Dakubo J
- Dal Canto M
- Dalli J
- Dally C
- Dambrauskas Z
- Dambrauskas Z
- Dan I
- Danelli P
- Daniels I
- Daniyan M
- Danys D
- Dao W
- Daqeeq A
- Dar M
- Dar W
- Dardenne S
- Darweesh M
- Darwish AKZ
- Das A
- Das K
- Das S
- Dasari M
- Dashnyam E
- Dassah V
- Datta U
- Davenport R
- Davies J
- Davies R
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- Dawnay G
- Dawood K
- Dawoud H
- Dayie M
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- De Bono P
- De Bono P
- De Franciscis S
- De Luca E
- De Marco P
- De Sousa AV
- Deal R
- Dean R
- Deane C
- Debrah S
- Deckelbaum DL
- Decker E
- Dedekind B
- Dedey F
- Deichsel F
- Del Basso C
- del Pilar Paucar A
- Delforge X
- Dell A
- Dempster E
- Denakpo M
- Denewar A
- Depalma N
- Deputy M
- Der Y
- Dervenis C
- Despotidis V
- Desta S
- Deutschmann P
- Devadasar GH
- Dharamshi HA
- Dhillon D
- Di Franco F
- Di Martino N
- Di Saverio S
- Di Saverio S
- Diab A
- Diaconescu B
- Diaconescu I-B
- Dias S
- Diaz Vico T
- Diaz-Jover P
- Diaz-Zorrilla C
- Dick L
- Dickfos M
- Dickson L
- Dijan E
- Dimech T
- Din F
- Dindyal S
- Dindyal S
- Dione Parreno-Sacdalan M
- Dissanayake T
- Djivoh F
- Domini E
- Domini E
- Donnelly P
- Donoghue D
- Dorani RMNR
- Dorisme A
- dos Santos DV
- Dossou F
- Doughan S
- Doughty J
- Dousset B
- Dragatas D
- Drake TM
- Drake TM
- Drake TM
- Driscoll A
- Drungilas M
- Du Plessis D
- du Plooy F
- Du Toit F
- Duane T
- Dubois A
- Duffy L
- Duhoranenayo D
- Duinhouwer L
- Dulskas A
- Dwydar A
- Ebdewi H
- Ebidy M
- Ebidy MM
- Ebrahim OS
- Eduard P
- Edwards J
- Edye M
- Eid MM
- Eisner L
- Ekow M
- El Ashal G
- El Dahab AA
- El Deen KN
- El Gendy A
- El Gendy NH
- El Halawany M
- El Jamassi A
- El Kashash A
- El Kholy A
- El Magd AA
- El Mesery S
- El Sayed GS
- El Sayed IM
- El Shoura Y
- El-badawy HA
- El-Dien KS
- El-Dien KS
- El-Din RA
- El-Din SA
- El-Gizawy E
- El-Hamouly AS
- El-Kashef H
- El-Latif NK
- El-Ma'doul AS
- El-Rabaa S
- El-Sagheer N
- El-Sawy A
- El-Sehily A
- El-Shahat NS
- El-Sheemy H
- El-Taher E
- Elabdin HZ
- Elashmawy M
- Elashry R
- Elazab A
- Elazayem AA
- Elazoul M
- Elbanby E
- Elbanby ES
- Elbatahgy A
- Elbe P
- Elbermawy M
- Elbisomy KH
- Eldafrawy M
- Eldamaty L
- Eldeeb AZ
- Eldeen EA
- Eldin MAB
- EldosoukyMohammed A
- Elebute O
- Elebute O
- Elena G
- Elfarargy A
- Elfeki H
- Elfeki H
- Elfiky M
- Elfil M
- Elfouly N
- Elfouly N
- Elfouly Y
- Elfouly Y
- Elgebaly A
- Elgendy AH
- Elgendy FI
- Elgheriany M
- Elhadad A
- Elhadary NM
- Elhadry S
- Elhalawany E
- Elhamouly S
- Elhelbawy MS
- Elhendawy A
- Elhendawy AOA
- Elhoseny G
- Elhusseiny AAE
- Elizabeth Lopez C
- Elkadsh I
- Elkady F
- Elkelany A
- Elkelany A
- Elkelany A
- Elkelany A
- Elkhadrawi M
- Elkhalek EA
- Elkholy A
- Elkholy SS
- Elkolaly SS
- Elkorashy AM
- Ellison Q
- Elmashala A
- Elmasry M
- Elmelegy R
- Elmihy S
- Elnagar A
- Elnajjar MA
- Elnemr AE
- Elrazek AA
- Elsabbagh N
- Elsameea AA
- Elsawahly DME
- Elsawy A
- Elsayed M
- Elsayed M
- Elsayed N
- Elsayed NAR
- Elsayed ZM
- Elsebaaye AO
- Elsehimy M
- Elsemelawy R
- Elshaar M
- Elshaer K
- Elshaer M
- Elshaer M
- Elshafay AE
- Elshami M
- Elshanwany S
- Elsharkawy AA
- Elsheikh S
- Elsherbiney S
- Elsherbiny AS
- Elsherif FA
- Elshobary M
- Elsiddig M
- Elsobky S
- Elsorogy DEAA
- Elwaey A
- Elwakil H
- Elwan A
- Elwan A
- Elwy E
- Elzahed N
- Elzayat I
- Elzayat M
- Elzayyat I
- Elzowawi F
- Emadeldin D
- Emadeldin H
- Emara E
- Emile S
- Eng C
- English W
- Esam A
- Escalante Salas MDC
- Espin-Basany E
- Espinoza F
- Essam A
- Essam AA
- Essam M
- Essoun S
- Esteban E
- Estee MM
- Estupinian S
- Etchill E
- Etchill E
- Etienne S
- Etman M
- Etwire V
- Evajelista CV
- Evans D
- Evans E
- Eysa A
- Eyssartier E
- Ezzat E
- Ezzat T
- Faboya O
- Faccincani R
- Fadel A
- Fahiem A
- Fahim M
- Fahmy MAB
- Fahy C
- Fairfield C
- Fairfield C
- Fairfield C
- Fairfield C
- Fakher R
- Falaschi F
- Falco N
- Falzon M
- Farag A
- Farag S
- Farah A
- Farahat MM
- Faraz A
- Fares M
- Farhad M
- Farhan-Alanie MMH
- Farhangmehr N
- Farinella E
- Farmakis K
- Farooq T
- Farouk SAM
- Farquharson A
- Farrugia A
- Farrugia A
- Faruq A
- Fathy AM
- Fattah AA
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe CO
- Fergany A
- Fergusson SJ
- Fergusson SJ
- Fergusson SJ
- Fergusson SJ
- Fermani C
- Fermani CG
- Fernandes C
- Fernandez C
- Fernandez-Bueno F
- Fernandez-Vega L
- Ferousis C
- Ferrero E
- Fievet L
- Filatau A
- Findlay-Cooper K
- Firdouse M
- Firdouse M
- Firdouse M
- Firwana A
- Fitsum A
- Fitzgerald JE
- Fitzgerald JE
- Florez Farfan ES
- Foco M
- Fok CYJ
- Fontana T
- Foo CC
- Forlin L
- Forno W
- Fouad A
- Fouad D
- Fouad D
- Fourcade L
- Fowler AJ
- Fozard T
- Fozard T
- Frade F
- Fraga GP
- Francisco Roxas M
- Franco H
- Francois P
- Francois-Coridon H
- Francone E
- Freitas AV
- Frey D
- Frisk B
- Fuentes-Rivera L
- Fujii F
- Furqan MM
- Gaafar S
- Gaarder T
- Gad A
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- Wold TB
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- Yifieyeh A
- Yildirim R
- Yip C
- Ymeri S
- Yoganathan P
- Yolcu S
- Yong CO
- Yong GL
- Younis A
- Youssef D
- Youssef H
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- Zani A
- Zani A
- Zani A
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- Zanini N
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- Zapata Ponze De Leon M
- Zapata F
- Zarb C
- Zardab A
- Zegarra S
- Zeidan S
- Zelada Alvarez II
- Zerihun AB
- Zeta Solis LA
- Zhang Z
- Zheng F
- Zidan H
- Zidan H
- Zidan M
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- Ziff O
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- Zil-E-Ali A
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskiene R
- Zilinskiene R
- Zimmermann EF
- Ziubryte G
- Zohair A
- Zorrilla CD
- Zuber M
- Zuber M
- Zuk G
- Zulkifli A
- Zumbuhl L
- Publication venue
- Publication date
- 15/10/2018
- Field of study
Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
Neisseria meningitidiselicits a pro-inflammatory response involving IκBζ in a human blood-cerebrospinal fluid barrier model
- Author
- A Jaerve
- A Schubert-Unkmeir
- A Spandidos
- A Subramanian
- A Unkmeir
- AC Pridmore
- AE Deghmane
- AE Deghmane
- AM van Furth
- B Engelhardt
- B Engelhardt
- B Pron
- BT McGuinness
- C Schoen
- C Schwerk
- C Schwerk
- Carolin Stump-Guthier
- Christel Weiss
- Christian Schwerk
- DB Wells
- DS Stephens
- DV Trinh
- E Carbonnelle
- ER van der Voort
- H Claus
- H Claus
- H Haruta
- H Kitamura
- H Schneider
- HEE Wong
- Hiroshi Ishikawa
- Horst Schroten
- I Ishiwata
- J Gerber
- J Guarner
- J Lorenz
- J Vandesompele
- JA Hagar
- JA Hamilton
- JR Weber
- Julia Borkowski
- K Cartwright
- K Matsushita
- KA Jolley
- KJ Laing
- KS Spanaus
- L Benga
- Li Li
- M Ashburner
- M Bsibsi
- M Christodoulides
- M Segura
- M Virji
- M Yamamoto
- M Yamamoto
- MG Tauber
- MI Fowler
- MS Hayden
- N Kayagaki
- N Laflamme
- N Laflamme
- Natascha Quednau
- NM van Sorge
- Norbert Gretz
- O Join-Lambert
- P Brandtzaeg
- P Lupo
- P Massari
- P Nagyoszi
- Peter Findeisen
- PJ Royer
- R Graveline
- S Akira
- S Akira
- S Hammerschmidt
- S Hammerschmidt
- S Lefever
- S Ram
- S Rozen
- S Seshadri
- S Yamazaki
- SJ Chapman
- SM Zughaier
- SM Zughaier
- T Beissbarth
- T Kawai
- T Kobayashi
- T Tenenbaum
- TH Mogensen
- Tobias Tenenbaum
- U Koedel
- U Koedel
- U Steinmann
- Ulrike Steinmann
- VK Mootha
- WM Scheld
- X Nassif
- X Wang
- Y Kajiwara
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Programmed cell death and its role in inflammation
- Author
- A Caudrillier
- A Degterev
- A Linkermann
- A Linkermann
- A Polykratis
- A Roghanian
- A Simon
- A Simonsen
- AB Molofsky
- AB Wardini
- AK Gupta
- AM Fitzpatrick
- AW Puri
- B Fadeel
- B Raupach
- B Ravikumar
- B Siegmund
- BG Yipp
- BS Franklin
- C Beauvillain
- C Gunther
- C Haslett
- C Moon
- CA Anderson
- CF Urban
- CG Persson
- CN Serhan
- CS Shi
- D Hersh
- D Holzinger
- D Park
- D Schmid
- DC Rubinsztein
- DH Abdelaziz
- DJ Mahoney
- DM Monack
- DM Rosenbaum
- DN Douda
- DS Zamboni
- E Itakura
- E Varfolomeev
- EL Eskelinen
- F Wartha
- FH Pilsczek
- G Ferwerda
- G Kroemer
- GM Thomas
- GP Schielke
- GP Sims
- GW Sun
- H Hilbi
- H Mulcahy
- HH Ng
- HM Shen
- I Ceballos-Olvera
- I Tabas
- IE Wertz
- IJ Juncadella
- IM Ghobrial
- J Harris
- J Harris
- J Lin
- J Masumoto
- J Moltke von
- J Xu
- J Zhao
- JA Duncan
- JA Hagar
- JD Lambeth
- JH Pedra
- JJ Chae
- JM Murphy
- JS Savill
- JT Buchanan
- JW Lee
- JW Upton
- JW Upton
- K Leyen van
- K McPhillips
- K Morimoto
- K Nakahira
- K Nakanishi
- KE Barletta
- KH Eum
- KM Averette
- KS Ravichandran
- L Andera
- L Duprez
- L Galluzzi
- L Gurcel
- L Henckaerts
- L Ouyang
- L Sun
- LH Travassos
- M Artal-Sanz
- M Bianchi
- M Cepkova
- M Feoktistova
- M Filimonenko
- M Hayakawa
- M Lara-Tejero
- M Maccarrone
- M Miyanishi
- M Nakaya
- M Suzanne
- MA Brennan
- MA Delgado
- MA O'Donnell
- MG Gutierrez
- MI Oerlemans
- MJ Bertrand
- ML Huynh
- ML Huynh
- N Craddock
- N Delaleu
- N Festjens
- N Furuta
- N Kayagaki
- N Kobayashi
- N Methot
- N Mizushima
- N Mizushima
- N Robinson
- NM Tsuji
- P Jezek
- P Kelk
- P Li
- P Li
- P Thumbikat
- P Vandenabeele
- PJ Sansonetti
- PS Welz
- Q Chen
- Q Remijsen
- R Chavez-Valdez
- R Cooney
- R Pierini
- RC Taylor
- RJ Thapa
- RL Zemans
- RS Hotchkiss
- RS Hotchkiss
- RW Vandivier
- RW Watson
- S Bruns
- S Feng
- S Frantz
- S He
- S Hodge
- S Hosogi
- S Jaillon
- S Mariathasan
- S Orozco
- S Sakon
- S Shimizu
- S Wang
- S Wang
- SB Singh
- SB Willingham
- SJ Kang
- SJ Martin
- SL Farnworth
- SL Fink
- SL Fink
- SY Park
- T Bergsbaken
- T Johansen
- T Narasaraju
- T Ren
- T Saitoh
- T Vanden Berghe
- TA Fuchs
- TL Roberts
- TS Plantinga
- U Koedel
- V Brinkmann
- V Brinkmann
- V Papayannopoulos
- V Papayannopoulos
- V Sagulenko
- VA Fadok
- VO Ona
- W Declercq
- WJ Kaiser
- X Chen
- X Teng
- XN Wu
- Y Aachoui
- Y Chen
- Y Dondelinger
- Y Xu
- YO Zhao
- YS Cho
- YT Wu
- Z Wen
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 19/05/2015
- Field of study
Cell death plays an important role in the regulation of inflammation and may be the result of inflammation. The maintenance of tissue homeostasis necessitates both the recognition and removal of invading microbial pathogens as well as the clearance of dying cells. In the past few decades, emerging knowledge on cell death and inflammation has enriched our molecular understanding of the signaling pathways that mediate various programs of cell death and multiple types of inflammatory responses. This review provides an overview of the major types of cell death related to inflammation. Modification of cell death pathways is likely to be a logical therapeutic target for inflammatory diseases
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