Deformations of quantum field theories on spacetimes with Killing vector fields

The recent construction and analysis of deformations of quantum field theories by warped convolutions is extended to a class of curved spacetimes. These spacetimes carry a family of wedge-like regions which share the essential causal properties of the Poincare transforms of the Rindler wedge in Minkowski space. In the setting of deformed quantum field theories, they play the role of typical localization regions of quantum fields and observables. As a concrete example of such a procedure, the deformation of the free Dirac field is studied.Comment: 35 pages, 3 figure

Search for coherent elastic neutrino-nucleus scattering at a nuclear reactor with CONNIE 2019 data

The Coherent Neutrino-Nucleus Interaction Experiment (CONNIE) is taking data at the Angra 2 nuclear reactor with the aim of detecting the coherent elastic scattering of reactor antineutrinos with silicon nuclei using charge-coupled devices (CCDs). In 2019 the experiment operated with a hardware binning applied to the readout stage, leading to lower levels of readout noise and improving the detection threshold down to 50 eV. The results of the analysis of 2019 data are reported here, corresponding to the detector array of 8 CCDs with a fiducial mass of 36.2 g and a total exposure of 2.2 kg-days. The difference between the reactor-on and reactor-off spectra shows no excess at low energies and yields upper limits at 95% confidence level for the neutrino interaction rates. In the lowest-energy range, 50-180 eV, the expected limit stands at 34 (39) times the standard model prediction, while the observed limit is 66 (75) times the standard model prediction with Sarkis (Chavarria) quenching factors.Comment: 23 pages, 14 figure

Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research

26th Annual Computational Neuroscience Meeting (CNS*2017): Part 3 - Meeting Abstracts - Antwerp, Belgium. 15–20 July 2017

This work was produced as part of the activities of FAPESP Research,\ud Disseminations and Innovation Center for Neuromathematics (grant\ud 2013/07699-0, S. Paulo Research Foundation). NLK is supported by a\ud FAPESP postdoctoral fellowship (grant 2016/03855-5). ACR is partially\ud supported by a CNPq fellowship (grant 306251/2014-0)

Modelling human choices: MADeM and decision‑making

Research supported by FAPESP 2015/50122-0 and DFG-GRTK 1740/2. RP and AR are also part of the Research, Innovation and Dissemination Center for Neuromathematics FAPESP grant (2013/07699-0). RP is supported by a FAPESP scholarship (2013/25667-8). ACR is partially supported by a CNPq fellowship (grant 306251/2014-0)

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Remediación de suelos contaminados con plomo (II) por fitotecnologías correctivas - Medicago sativa L. (Alfalfa)

La concentración de plomo es variable y depende de la situación. De manera natural, el plomo presenta una concentración de 10-50 mg/kg, pero, la actividad humana aumenta en 10 a 200 veces; el plomo atmosférico se aproxima a 10μg/m3 de aire; Pb disuelto en aguas p.e. del río Bogotá (Colombia) presenta una concentración de 49,77 KgPb/día. Medicago sativa L., se emplea como especie vegetal bioacumuladora. Los suelos del Centro Agropecuario Marengo de la Universidad Nacional de Colombia; Sede Bogotá, fueron usados para la experimentación, teniendo en cuenta que al interior de dicho Centro circula un canal de riego el cual se alimenta con aguas de la cuenca media del Rio Bogotá. Se colectaron suelos in-situ y su estudio se llevó a cabo de forma in-vitro en el Instituto Geográfico Agustín Codazzi. Un análisis factorial con dos factores y un diseño de bloques completos aleatorizados fue establecido, lo que permitió analizar la interacción de dos variables principales: pH y [Pb]-incubado. Alfalfa acumula alrededor de 62% de plomo en el suelo a pH = 5,5; 32% más en comparación con las especies de plantas (malezas) que crecen en los suelos experimentales a pH = 5,4. Alfalfa tiene la capacidad gradual de acumulación de plomo a pH = 5.5, principalmente en las hojas en comparación con tallos y raíces. Aunque los suelos experimentales se riegan con aguas del río Bogotá, éstos no pueden ser considerados con niveles excesivos de plomo que ameriten aplicar tecnologías de fito-remediación. A pesar de que se emplean aguas del rio Bogotá para el riego agrícola, no es posible afirmar alguna tendencia creciente de acumulación en los suelos; por lo menos no en los suelos experimentales

Octenilsuccinato alumínico de almidón de quinua – grado cosmético – y su certificación bajo la denominación de “ingrediente natural”

Se da a conocer el proceso para evaluar/obtener/certificar octenilsuccinato alumínico de almidón de quinua - grado cosmético (OSAlAQ), con la denominación de ingrediente natural. El proceso consistió en dos fases: a) reacción de esterificación, bajo método “Simila”; parámetros: tiempo de reacción 4 horas, temperatura de reacción de 35oC, pH de reacción de 8.5 y una concentración de almidón de 35% p/p. “Similb” corresponde a la segunda reacción de sustitución fundamentada en Cosmetic Ingredient Review Expert Panel, que usa sulfato de aluminio al 2%; requerimiento en cosmética. Para la certificación se debe tener en cuenta algunas reglas de producción: a) Las operaciones de producción de OSAlAQ, referidas a la fabricación, envasado y embalaje, se efectuaron bajo ficha explicativa TS033. La producción de OSAlAQ involucró procedimientos de trituración, tamización, extracción con agua, decantación, filtración. El procedimiento químico empleado fue el de esterificación. b) Sobre las operaciones de limpieza y desinfección, antes y después, se garantiza la ausencia de contaminación con un producto no conforme, y se reduce el impacto ambiental de la producción del producto final. c) Las condiciones de almacenamiento y de transporte permitieron asegurar trazabilidad completa y eliminar todo riesgo de contaminación, de confusión o de mezcla

Beef consumption and fatty acids serum concentration: relationship with salivary gland tumors in Córdoba, Argentina

The objective of the present study was to analyze beef consumption, conjugated linoleic acid (CLA) and n-3 fatty acid (FA) serum concentration and their relation to salivary gland tumors (SGT). A questionnaire on non-nutritional risk factors and a validated food frequency questionnaire were applied in 20 SGT and 20 control (Co) patients. Materials and Methods: Food data were processed by the Interfood v.1.3 software. Serum CLA was analyzed by chromatography. Results: Non-significant differences were found between SGT and Co regarding lean and fatty BC and serum CLA. Serum n-3 linolenic acid concentration was higher in Co than in SGT (p=0.004). No associations between BC and CLA serum concentration were found, but a strong-positive association between total energy intake and total fat intake and SGT were observed. A significant inverse association between oleic and linoleic FA intake and SGT was recorded. Conclusion: Serum oleic and linolenic FAs showed a significant negative association with SGT.http://ar.iiarjournals.org/content/34/10/5579.long#sec-3publishedVersionFil: Cittadini, María C. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Escuela de Nutrición; Argentina.Fil: Cornaglia, Paola M. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas. Instituto de Estadística y Demografía; Argentina.Fil: Joekes, Silvia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas. Instituto de Estadística y Demografía; Argentina.Fil: Perovic, Nilda R. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Escuela de Nutrición; Argentina.Fil: Heinze, Verónica M. Universidad Adventista del Plata. Facultad de Ciencias de la Salud; Argentina.Fil: Bernal, Claudio. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas; Argentina.Fil: Actis, Adriana B. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ciencias de la Salud; Argentina.Fil: Actis, Adriana B. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; Argentina.Otras Ciencias de la Salu