Queering the Sublime: Virginia Woolf, Sexology, and Sexuality

Using Virginia Woolf\u27s novels, The Voyage Out, Mrs. Dalloway, To the Lighthouse, and Orlando, I begin to explore moments where the characters experience the sublime as defined by Edmund Burke. Woolf uses the traditional sublime, but complicates the concept beyond its initial intention. The moments that mimic the sublime, but include the body, the natural world, and artistic creativity grows into what I will call the queer sublime, which is new for both Woolf scholarship and for the sublime. Woolf\u27s experimentation with the term and part of the queer sublime also helps to create a different understanding of lesbian relationships and sexual pleasure than the prevalent ideas of day. Sexologists, such as Havelock Ellis, examine lesbians and their sex lives, but they remove the sexual body from their observations, and reinforce a Victorian understanding of heterosexual sex. Using the sublime as defined by Edmund Burke as a framework, the theories of Elizabeth Grosz as regards art and the natural world, Woolf\u27s ultimate manifestation of the sublime is examined

The Zika Virus Threat: How Concerns About Scientists May Undermine Efforts to Combat the Pandemic

Using data from the University of New Hampshire’s October 2016 Granite State Poll, authors Thomas Safford, Lawrence Hamilton, and Emily Whitmore investigate how New Hampshire residents view the Zika crisis. They report that most New Hampshire residents believe Zika is only a minor threat to public health in the United States, and they generally trust the CDC as a source of information about the virus. The data also show that, while there is doubt about the government’s ability to control the spread of the virus, the public feels that emergency federal funding to combat Zika should be a priority. They discuss that many Granite Staters have real concerns about the practice of science, believing scientists change their findings to get the answers they want. More importantly, individuals who questioned the integrity of scientists are less likely to believe Zika is a threat, have confidence in the government’s ability to combat the virus, trust the CDC, and to prioritize emergency funding. They conclude that these results suggest that health officials working to engage the public in efforts to control the spread of Zika must not only discuss risks associated with the virus and mechanisms of transmission, but also confront science skepticism and potential concerns about the integrity of the scientists gathering data related to Zika and other infectious diseases

A MIXED METHODS APPROACH TO SOCIAL LICENSE TO OPERATE FOR AQUACULTURE: UNDERSTANDING HOW BROAD PUBLIC PERCEPTIONS AND LOCAL COMPANY ACTIONS INFLUENCE COMMUNITY ACCEPTANCE

With aquaculture development becoming increasingly important in meeting global food needs, understanding social dynamics of development is essential. Social license to operate (SLO), a concept that describes community acceptance and approval of incoming industry, offers a lens into these dynamics and possible strategies for successful development. Using a mixed-methods approach, this project aimed to investigate how broad public perceptions and local company actions influence social license to operate in aquaculture. First, a systematic literature review of SLO studies identified perceptions that would likely condition a community’s willingness to issue social license, independent of company actions. These predictors included environmental values, economic values, use-conflict, knowledge of aquaculture, experience with aquaculture, confidence in government, and perceptions of the safety of farmed seafood. Second, data from a nationally representative survey validated six of the seven themes as significant predictors of acceptability of aquaculture here in the US. Third, interviews with 30 Maine shellfish and seaweed farmers identified specific strategies used by farmers to earn trust from stakeholders, offering insights into state-specific barriers to social license for aquaculture. As stand-alone pieces, these three chapters add to a growing body of work on social license in aquaculture. The first chapter enhances SLO measurement, providing a community-focused framework that could be refined to help to identify communities that would benefit from and be receptive of aquaculture activity. The second chapter validates these predictors, but also expands research related to public perceptions of aquaculture more broadly. This chapter demonstrates that key predictors found in studies from across the globe are also relevant here in the US. The third chapter, though structured as an applied guidebook for SLO, contributes to several research gaps including understanding of the social networks that exist around aquaculture development, the community benefits offered by aquaculture, the ways that aquaculture companies incorporate SLO activity into their business strategies, and the relationship between third party certifications and SLO in aquaculture. Together, this body of work offers insights into the relationship between public perceptions, community dynamics, and social license. While farmers relay specific strategies used to gain local trust, they acknowledge that community context and pre-existing perceptions affect success. Considering public knowledge of aquaculture is low, perceptions are often formed through local experiences. For farmers, social license as a heuristic encourages creating positive experiences for community members. Collectively, these experiences could bolster support for the industry more broadly, acting as a catalyst for future growth. Further, putting community at the forefront leads to a more socially sustainable industry, where industry members are aware and attentive of social concerns. Though there is still much work to be done, this project highlights the utility and necessity of social license to operate as a way of thinking within aquaculture as well as natural resource industries more broadly

Picturebooks and gender : making informed choices for equitable early childhood classrooms.

We examine picturebooks through a feminist lens, understanding that children’s literature and media can limit and expand how young children access gender representations. We describe four categories that increase teacher knowledge to select books with multiple and varied gender representations for children in their classrooms. These four categories are gender binaries, discourses of childhood innocence, intersectionality, and heteronormativity. We illustrate each category with two quality books that maintain and disrupt each theme. We hope teachers will find the categories useful for thoughtfully selecting books for classroom libraries, read aloud, and discussion

The Zika Virus Threat

Shocking images of infants with severe birth defects in Brazil introduced the world to the devastating effects of the Zika virus. This mosquito-borne illness spread rapidly across Latin America and into the United States. News stories highlighting locally transmitted cases of Zika in Florida, and most recently in Texas, created a sense of urgency among public health officials. They stepped up efforts to inform the public about the transmission of the virus as well as the health risks associated with Zika. Public polling shows that Americans are becoming increasingly concerned about the threat of Zika, and they question the government's ability to limit its spread. What is less clear are the factors influencing perceptions of the Zika pandemic and support for governmental efforts to curb the spread of the virus

Follow the Scientists? How Beliefs about the Practice of Science Shaped COVID-19 Views

“Follow the science” became the mantra for responding to COVID-19 pandemic. However, for the public this also meant “follow the scientists,” and this led to uneasiness as some viewed scientists as not credible. We investigate how beliefs about the way scientists develop their findings affect pandemic-related views. Our analysis shows that beliefs about scientists’ objectivity predict views regrading coronavirus-related risks, behavioral changes, and policy priorities. While political party identity also predicts views about COVID-19-related concerns, these vary by political leaders whose approaches embraced versus dismissed science based strategies, highlighting the importance of perceptions of scientists in shaping pandemic related attitudes and beliefs

Forward genetic screen of homeostatic antibody levels in the Collaborative Cross identifies MBD1 as a novel regulator of B cell homeostasis

Variation in immune homeostasis, the state in which the immune system is maintained in the absence of stimulation, is highly variable across populations. This variation is attributed to both genetic and environmental factors. However, the identity and function of specific regulators have been difficult to identify in humans. We evaluated homeostatic antibody levels in the serum of the Collaborative Cross (CC) mouse genetic reference population. We found heritable variation in all antibody isotypes and subtypes measured. We identified 4 quantitative trait loci (QTL) associated with 3 IgG subtypes: IgG1, IgG2b, and IgG2c. While 3 of these QTL map to genome regions of known immunological significance (major histocompatibility and immunoglobulin heavy chain locus), Qih1 (associated with variation in IgG1) mapped to a novel locus on Chromosome 18. We further associated this locus with B cell proportions in the spleen and identify Methyl-CpG binding domain protein 1 under this locus as a novel regulator of homeostatic IgG1 levels in the serum and marginal zone B cells (MZB) in the spleen, consistent with a role in MZB differentiation to antibody secreting cells

Differential lipid dependence of the function of bacterial sodium channels

The lipid bilayer is important for maintaining the integrity of cellular compartments and plays a vital role in providing the hydrophobic and charged interactions necessary for membrane protein structure, conformational flexibility and function. To directly assess the lipid dependence of activity for voltage-gated sodium channels, we compared the activity of three bacterial sodium channel homologues (NaChBac, NavMs, and NavSp) by cumulative 22Na+ uptake into proteoliposomes containing a 3:1 ratio of 1-palmitoyl 2-oleoyl phosphatidylethanolamine and different “guest” glycerophospholipids. We observed a unique lipid profile for each channel tested. NavMs and NavSp showed strong preference for different negatively-charged lipids (phosphatidylinositol and phosphatidylglycerol, respectively), whilst NaChBac exhibited a more modest variation with lipid type. To investigate the molecular bases of these differences we used synchrotron radiation circular dichroism spectroscopy to compare structures in liposomes of different composition, and molecular modeling and electrostatics calculations to rationalize the functional differences seen. We then examined pore-only constructs (with voltage sensor subdomains removed) and found that in these channels the lipid specificity was drastically reduced, suggesting that the specific lipid influences on voltage-gated sodium channels arise primarily from their abilities to interact with the voltage-sensing subdomains

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements