1,537 research outputs found
A compendium and functional characterization of mammalian genes involved in adaptation to Arctic or Antarctic environments
- Author
- A Babes
- A Cardona
- A Wells
- A Zarbock
- AC Bianco
- AC Johnson
- AE Locke
- AM Hancock
- AM Hancock
- AM Hancock
- C Brenker
- CA Ottenheijm
- CT Williams
- DA Diesel
- Denis M. Larkin
- DF Rolfe
- DL Ingram
- E Eden
- E Ramos-Sevillano
- EA Tansey
- EG Mourtzoukou
- Elena V. Ignatieva
- EV Ignatieva
- EV Ignatieva
- EV Ignatieva
- F Li
- FJ Wei
- FM Petit
- GG Giesbrecht
- GJ Tattersall
- H Kobayashi
- HB Stoner
- HJ Choi
- HS Yim
- I Turcan
- IG Shabalina
- J Dai
- J Grosse-Onnebrink
- J Simcox
- J Stapley
- JA McGrath
- JL1 Salisbury
- JM Bono
- JY Park
- K Hueffer
- KC Wollenberg Valero
- L Lin
- L Pastenes
- LM Boyden
- LN Suri
- M Bagheri Varzaneh
- M Delahunty
- M Fumagalli
- M Ostrowski
- M Sazzini
- M Shiota
- M Vornanen
- MA Carrasco
- MA Iakimenko
- MA McAleer
- MH Sedaghat
- NA Abumrad
- Nikolay S. Yudin
- NT Loges
- O Savolainen
- P Librado
- P Venditti
- PF Scholander
- PR1 Stabach
- Q Zhao
- R Corominas
- RD Barrett
- S Bröer
- S Fan
- S Hoban
- S Labeit
- S Liu
- S Ma
- SA Barnett
- SA Savage
- SF Bailey
- SM González-Renteria
- T Yoshida
- V Kumar
- VG Levitsky
- VJ Lynch
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/12/2017
- Field of study
Many mammals are well adapted to surviving in extremely cold environments. These species have likely accumulated genetic changes that help them efficiently cope with low temperatures. It is not known whether the same genes related to cold adaptation in one species would be under selection in another species. The aims of this study therefore were: to create a compendium of mammalian genes related to adaptations to a low temperature environment; to identify genes related to cold tolerance that have been subjected to independent positive selection in several species; to determine promising candidate genes/pathways/organs for further empirical research on cold adaptation in mammals
Search for new physics with same-sign isolated dilepton events with jets and missing transverse energy
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abdulsalam A
- Acosta D
- Acosta JG
- Adair A
- Adam N
- Adam W
- Adams JR
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
- Akgun B
- Akgun U
- Akin IV
- Alagoz E
- Albajar C
- Albayrak EA
- Albergo S
- Albrow M
- Alcaraz Maestre J
- Alda Junior WL
- Aldaya Martin M
- Alexander J
- Aliev T
- Alimena J
- Almeida N
- Alverson G
- Alves GA
- Amapane N
- Amsler C
- Anagnostou G
- Anastassov A
- Anderson J
- Anderson M
- Andrea J
- Andreev V
- Andreev V
- Andreev Y
- Andrews W
- Anghel IM
- Antonelli L
- Antunovic Z
- Apanasevich L
- Appelt E
- Apresyan A
- Arce P
- Arcidiacono R
- Arenton MW
- Arfaei H
- Argiro S
- Arneodo M
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- Asawatangtrakuldee C
- Asghar MI
- Askew A
- Assran Y
- Ata M
- Attikis A
- Auffray E
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- Auzinger G
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- Wyslouch B
- Xiao H
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- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
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- Yu I
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- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
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- Zatserklyaniy A
- Zeinali M
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- Zeuner WD
- Zeyrek M
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- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Zielinski M
- Zito G
- Zou W
- Zucchetta A
- Zumerle G
- Zuranski A
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
A search for new physics is performed in events with two same-sign isolated
leptons, hadronic jets, and missing transverse energy in the final state. The
analysis is based on a data sample corresponding to an integrated luminosity of
4.98 inverse femtobarns produced in pp collisions at a center-of-mass energy of
7 TeV collected by the CMS experiment at the LHC. This constitutes a factor of
140 increase in integrated luminosity over previously published results. The
observed yields agree with the standard model predictions and thus no evidence
for new physics is found. The observations are used to set upper limits on
possible new physics contributions and to constrain supersymmetric models. To
facilitate the interpretation of the data in a broader range of new physics
scenarios, information on the event selection, detector response, and
efficiencies is provided.Comment: Published in Physical Review Letter
Compressed representation of a partially defined integer function over multiple arguments
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdelalim AA
- Abdullin S
- Abdulsalam A
- Acosta D
- Acosta MV
- Adair A
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agram J-L
- Aguilar-Benitez M
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
- Akgun B
- Akgun U
- Akin IV
- Alagoz E
- Albajar C
- Albayrak EA
- Albergo S
- Albrow M
- Alcaraz Maestre J
- Alda Junior WL
- Alderweireldt S
- Alexander J
- Aliev T
- Alimena J
- Almeida N
- Alverson G
- Alves GA
- Amapane N
- Amsler C
- Anagnostou G
- Anastassov A
- Anderson J
- Andrea J
- Andreev V
- Andreev V
- Andreev Y
- Andrews W
- Androsov K
- Antonelli L
- Antunovic Z
- Apanasevich L
- Apollinari G
- Appelt E
- Apresyan A
- Apyan A
- Arcidiacono R
- Arenton MW
- Arfaei H
- Argiro S
- Arneodo M
- Arora S
- Asavapibhop B
- Asawatangtrakuldee C
- Asghar MI
- Asin I
- Askew A
- Aslanoglou X
- Assran Y
- Ata M
- Attikis A
- Auffray E
- Autermann C
- Auzinger G
- Avdeeva E
- Avery P
- Avetisyan A
- Avila C
- Azarkin M
- Azhgirey I
- Aziz T
- Azzi P
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- Publication venue
- Publication date
- 01/01/2013
- Field of study
In OLAP (OnLine Analitical Processing) data are analysed in an n-dimensional cube. The cube may be represented as a partially defined function over n arguments. Considering that often the function is not defined everywhere, we ask: is there a known way of representing the function or the points in which it is defined, in a more compact manner than the trivial one
Measurement of jet fragmentation into charged particles in pp and PbPb collisions at sqrt(s[NN]) = 2.76 TeV
- Author
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- Zhang Z
- Zheng Y
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2012
- Field of study
Jet fragmentation in pp and PbPb collisions at a centre-of-mass energy of
2.76 TeV per nucleon pair was studied using data collected with the CMS
detector at the LHC. Fragmentation functions are constructed using
charged-particle tracks with transverse momenta pt > 4 GeV for dijet events
with a leading jet of pt > 100 GeV. The fragmentation functions in PbPb events
are compared to those in pp data as a function of collision centrality, as well
as dijet-pt imbalance. Special emphasis is placed on the most central PbPb
events including dijets with unbalanced momentum, indicative of energy loss of
the hard scattered parent partons. The fragmentation patterns for both the
leading and subleading jets in PbPb collisions agree with those seen in pp data
at 2.76 TeV. The results provide evidence that, despite the large parton energy
loss observed in PbPb collisions, the partition of the remaining momentum
within the jet cone into high-pt particles is not strongly modified in
comparison to that observed for jets in vacuum.Comment: Submitted to the Journal of High Energy Physic
Measurement of the t t-bar production cross section in the dilepton channel in pp collisions at sqrt(s) = 7 TeV
- Author
- A. A. Ocampo Rios
- A. Abdulsalam
- A. Adair
- A. Adiguzel
- A. Anastassov
- A. Apresyan
- A. Apyan
- A. Askew
- A. Attikis
- A. Avetisyan
- A. B. Meyer
- A. Baden
- A. Barker
- A. Bean
- A. Belyaev
- A. Belyaev
- A. Benaglia
- A. Beretvas
- A. Bethani
- A. Bhardwaj
- A. Bhatti
- A. Bocci
- A. Bodek
- A. Bonato
- A. Bornheim
- A. Branca
- A. Brinkerhoff
- A. Burgmeier
- A. C. Benvenuti
- A. C. Marini
- A. C. Mignerey
- A. Cakir
- A. Calderon
- A. Campbell
- A. Castro
- A. Chatterjee
- A. Cimmino
- A. Colaleo
- A. Custódio
- A. Dabrowski
- A. David
- A. De Benedetti
- A. De Cosa
- A. De Roeck
- A. Deisher
- A. Delgado Peris
- A. Dermenev
- A. Descroix
- A. Dierlamm
- A. Dimitrov
- A. Dominguez
- A. Drozdetskiy
- A. Elliott-Peisert
- A. Ellithi Kamel
- A. Ershov
- A. Everett
- A. F. Barfuss
- A. F. Osorio Oliveros
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- A. Ferapontov
- A. Ferrando
- A. G. Delannoy
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- A. Geiser
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- A. Giammanco
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- A. Gilbert
- A. Givernaud
- A. Godshalk
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- A. Guneratne Bryer
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- A. Güth
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- A. Harel
- A. Heikkinen
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- B. Wyslouch
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- C. Amsler
- C. Asawatangtrakuldee
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- C. Avila
- C. Barth
- C. Battilana
- C. Bernet
- C. Biino
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- C. Boulahouache
- C. Brew
- C. Broutin
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- C. Campagnari
- C. Charlot
- C. Civinini
- C. Collard
- C. Contreras-Campana
- C. De Oliveira Martins
- C. Delaere
- C. Dietz
- C. Diez Pardos
- C. Dozen
- C. Dragoiu
- C. E. Gerber
- C. Fabjan
- C. Fanelli
- C. Fantasia
- C. Farrell
- C. Favaro
- C. Fernandez Bedoya
- C. Ferro
- C. Florez
- C. Foudas
- C. Grab
- C. Grandi
- C. H. Jiang
- C. H. Shepherd-Themistocleous
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- C. Hajdu
- C. Hartl
- C. Heidemann
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- C. Jarvis
- C. Jeong
- C. Jessop
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- C. Justus
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- C. Kottachchi Kankanamge Don
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- C. Lourenço
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- C. Magass
- C. Maguire
- C. Mariotti
- C. Markou
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- C. Mavrommatis
- C. Mesropian
- C. Mironov
- C. Neu
- C. Newman-Holmes
- C. Nicolaou
- C. Nuttens
- C. Nägeli
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- C. Park
- C. Paus
- C. Plager
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- S. Wayand
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- S. Won
- S. Xie
- Sa. Jain
- Sandra S. Padula
- Sh. Jain
- T Sjöstrand
- T. Adams
- T. Aliev
- T. Aziz
- T. Bergauer
- T. Boccali
- T. Bolton
- T. Bose
- T. Caebergs
- T. Camporesi
- T. Cheng
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- T. Cornelis
- T. Dahms
- T. Danielson
- T. Dorigo
- T. du Pree
- T. Ferguson
- T. Frueboes
- T. Geralis
- T. Hauth
- T. Hebbeker
- T. Hermanns
- T. Hreus
- T. J. Kim
- T. J. Mertzimekis
- T. Kamon
- T. Karaman
- T. Khurshid
- T. Kolberg
- T. Kress
- T. Kurca
- T. Kypreos
- T. Lampén
- T. Libeiro
- T. Lindén
- T. Lomtadze
- T. Ma
- T. Martins
- T. Medvedeva
- T. Miceli
- T. Mäenpää
- T. Mäki
- T. Orimoto
- T. Pearson
- T. Peiffer
- T. Peltola
- T. R. Fernandez Perez Tomei
- T. Reis
- T. Rodrigo
- T. Rohe
- T. Rommerskirchen
- T. Rovelli
- T. S. Anjos
- T. Sakuma
- T. Scarborough
- T. Schoerner-Sadenius
- T. Schum
- T. Sinthuprasith
- T. Son
- T. Speer
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- T. Tuuva
- T. Virdee
- T. Weiler
- T. Whyntie
- T. Williams
- T. Y. Kim
- T. Y. Ling
- T. Yetkin
- Th. Müller
- U. Akgun
- U. Baur
- U. Behrens
- U. E. Surat
- U. Gasparini
- U. Gebbert
- U. Goerlach
- U. Grundler
- U. Heintz
- U. Joshi
- U. Langenegger
- V Ahrens
- V Khachatryan
- V Khachatryan
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- V. Blobel
- V. Brigljevic
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- V. Petrov
- V. Popov
- V. Rekovic
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- V. Sharma
- V. Sharma
- V. Smirnov
- V. Sola
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- V. Tcholakov
- V. Timciuc
- V. Valuev
- V. Veeraraghavan
- V. Veszpremi
- V. Zhukov
- V. Zhukova
- W. A. Khan
- W. Adam
- W. Andrews
- W. Behrenhoff
- W. Bertl
- W. Busza
- W. Carvalho
- W. Clarida
- W. D. Teo
- W. D. Zeuner
- W. De Boer
- W. Dominik
- W. Erdmann
- W. Ferguson
- W. Flanagan
- W. Funk
- W. H. Smith
- W. Haj Ahmad
- W. J. Spalding
- W. J. Womersley
- W. Johns
- W. Kiesenhofer
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- W. L. Aldá
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- W. Lange
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- W. Li
- W. Lin
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- W. Luo
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- W. Martin
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- W. Sun
- W. T. Ford
- W. To
- W. Van Doninck
- W. Waltenberger
- W. Wu
- W. Zou
- W.-S. Hou
- X. Janssen
- X. Meng
- X. Quan
- X. Shi
- X. T. Huang
- X. Wan
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- Y. Assran
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- Y. Cho
- Y. Choi
- Y. Eshaq
- Y. F. Liu
- Y. Fu
- Y. Gao
- Y. Gershtein
- Y. Guo
- Y. H. Chang
- Y. H. Chang
- Y. Hsiung
- Y. Iiyama
- Y. Ivanov
- Y. J. Lei
- Y. J. Lu
- Y. K. Choi
- Y. Kim
- Y. Kubota
- Y. Kuessel
- Y. Lu
- Y. M. Tzeng
- Y. Ma
- Y. Mao
- Y. Maravin
- Y. Musienko
- Y. Onel
- Y. Pakhotin
- Y. Roh
- Y. S. Chung
- Y. Sirois
- Y. Tschudi
- Y. Tu
- Y. W. Chang
- Y. Weng
- Y. Yang
- Y. Yilmaz
- Y. Zheng
- Y.-J. Lee
- Yu. Andreev
- Z. Antunovic
- Z. C. Yang
- Z. Hatherell
- Z. Hu
- Z. J. Guo
- Z. K. Liu
- Z. L. Trocsanyi
- Z. Staykova
- Z. Szillasi
- Z. Tsamalaidze
- Z. Wang
- Z. Zhang
- Zero J. Kim
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2012
- Field of study
The t t-bar production cross section (sigma[t t-bar]) is measured in
proton-proton collisions at sqrt(s) = 7 TeV in data collected by the CMS
experiment, corresponding to an integrated luminosity of 2.3 inverse
femtobarns. The measurement is performed in events with two leptons (electrons
or muons) in the final state, at least two jets identified as jets originating
from b quarks, and the presence of an imbalance in transverse momentum. The
measured value of sigma[t t-bar] for a top-quark mass of 172.5 GeV is 161.9 +/-
2.5 (stat.) +5.1/-5.0 (syst.) +/- 3.6(lumi.) pb, consistent with the prediction
of the standard model.Comment: Replaced with published version. Included journal reference and DO
The moose, purine degradation, and environmental adaptation
- Author
- A Belenguer
- A Guerouali
- A Hunter
- AA Tolun
- AJ Cabanac
- AW Bristow
- B Álvarez-Lario
- C Campo
- D Christianson
- DB Vagnoni
- DG Robertson
- G Ramirez
- GD DelGiudice
- GR Hawkins
- HE Mohamed
- J Keilin
- JC Surra
- JM Moorby
- Minghai Zhang
- ML Bakker
- P Venditti
- PH Proctor
- Philip Stott
- PJ White
- RA Garrott
- RG Cutler
- RJ Long
- S Sinha
- SK George
- TI Kochan
- W Zhang
- Weiqi Zhang
- WG Siems
- XB Chen
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Two Chromatin Remodeling Activities Cooperate during Activation of Hormone Responsive Promoters
- Author
- A Kouskouti
- A Migliaccio
- A. Silvina Nacht
- AH Hassan
- AH Hassan
- AI Nesvizhskii
- Ang Li
- B Belandia
- B Pina
- BD Strahl
- BR Cairns
- C Muchardt
- CJ Fryer
- CL Peterson
- E Korzus
- EH Bresnick
- F Wang
- Francois Le Dily
- GJ Narlikar
- GP Vicent
- GP Vicent
- GP Vicent
- Guillermo Pablo Vicent
- H Richard-Foy
- H Strutt
- I Whitehouse
- J Bartsch
- J Cox
- J Rappsilber
- JC Blanco
- JC Reyes
- JD Aalfs
- JD Dignam
- JM Garcia-Pedrero
- Jofre Font-Mateu
- JV Olsen
- K Luger
- KA Link
- L Di Croce
- L Mohrmann
- M Beato
- M Bruno
- M Kasten
- M Singh
- M Truss
- M Vermeulen
- Matthias Mann
- Michiel Vermeulen
- Miguel Beato
- MJ Carrozza
- NM Mulholland
- P Cheung
- P Venditti
- PB Hebbar
- PB Hebbar
- R Kane
- R Koop
- R Metivier
- R Narayanan
- RL Schiltz
- RM Gronostajski
- RN Bhattacharjee
- RN Bhattacharjee
- Roser Zaurin
- S Sif
- SM Roberts
- SY Roth
- T Agalioti
- T Mizutani
- TW Marshall
- W Shen
- W Wang
- W Wang
- WX Schulze
- X Yang
- XJ Yang
- Y Shang
- Y Xue
- Yoshihide Hayashizaki
- Z Nie
- Z Yan
- ZQ Huang
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2009
- Field of study
Steroid hormones regulate gene expression by interaction of their receptors with hormone responsive elements (HREs) and recruitment of kinases, chromatin remodeling complexes, and coregulators to their target promoters. Here we show that in breast cancer cells the BAF, but not the closely related PBAF complex, is required for progesterone induction of several target genes including MMTV, where it catalyzes localized displacement of histones H2A and H2B and subsequent NF1 binding. PCAF is also needed for induction of progesterone target genes and acetylates histone H3 at K14, an epigenetic mark that interacts with the BAF subunits by anchoring the complex to chromatin. In the absence of PCAF, full loading of target promoters with hormone receptors and BAF is precluded, and induction is compromised. Thus, activation of hormone-responsive promoters requires cooperation of at least two chromatin remodeling activities, BAF and PCAF
The multi-peak adaptive landscape of crocodylomorph body size evolution
- Author
- A Clauset
- A Lecuona
- A Prokoph
- A Purvis
- A Ősi
- AH Turner
- AH Turner
- AH Turner
- AH Turner
- AK Huttenlocker
- AM Davis
- AP Russell
- AW Kellner
- B Van Valkenburgh
- BJ Allen
- BJ MacFadden
- BK Ahlborn
- C Linnert
- C Venditti
- C Zhang
- CA Brochu
- CA Brochu
- CA Brochu
- CJJ Depéret
- CN Johnson
- CR McClain
- D Pol
- D Pol
- D Pol
- D Pol
- DF Wright
- DL Mahler
- DL Mahler
- DM Raup
- DO Fisher
- DW Bapst
- DW Bapst
- DW Bapst
- DW Bapst
- DW Bapst
- DW McShea
- DWE Hone
- ED Cope
- ED Cope
- EN Smith
- EP Martins
- EW Wilberg
- EW Wilberg
- EW Wilberg
- F Fanti
- F Ronquist
- F Ronquist
- FA Smith
- FA Smith
- FC Montefeltro
- FG Marx
- G Hunt
- G Hunt
- G Hunt
- G Hunt
- G Hunt
- G Hunt
- GC Grigg
- GE Hutchinson
- GG Simpson
- GG Simpson
- GJ Slater
- GJ Slater
- GJ Slater
- GJ Vermeij
- GJW Webb
- GM Cidade
- GM Erickson
- GP Burness
- GP Wilson
- GR Hurlburt
- GT Lloyd
- H Akaike
- HC Larsson
- HR Bustard
- IS Carvalho
- J Allsteadt
- J Alroy
- J Alroy
- J Clavel
- J Felsenstein
- J Felsenstein
- JC Uyeda
- JC Zachos
- JE Martin
- JF Downhower
- JJ Saarinen
- JL Carballido
- JM Beaulieu
- JM Clark
- JM Clark
- JM Clark
- JO Farlow
- JP Ross
- JP Tennant
- JP Tennant
- JP Tennant
- K Schmidt-Nielsen
- KP Burnham
- KP Burnham
- L Van Valen
- LE Zanno
- LJ Harmon
- LJ Harmon
- LJ Revell
- LST Ho
- M Bronzati
- M Bronzati
- M Cardillo
- M Churchill
- M Delfino
- M Delfino
- M Foote
- M Foote
- M Khabbazian
- M Laurin
- M Pagel
- M Pagel
- MA Butler
- MA Wills
- Mario Bronzati
- MD Ezcurra
- MJ Landis
- ML McKinney
- MM Johnson
- MS Lee
- MS Lee
- MT Alberdi
- MT Carrano
- MT Young
- MT Young
- MT Young
- MT Young
- MT Young
- MW Pennell
- N Brocklehurst
- N Cooper
- N Cooper
- N Sugiura
- NA Heim
- ND Newell
- NJ Matzke
- NR Longrich
- O Toljagić
- PC Sereno
- PD Mannion
- Pedro L. Godoy
- Philip D. Mannion
- PJ Markwick
- PJ Markwick
- PL Godoy
- PL Godoy
- PM Hall
- R Core Team
- RB Irmis
- RB Sookias
- RB Sookias
- RBJ Benson
- RBJ Benson
- RBJ Benson
- RBJ Benson
- RBJ Benson
- RH Peters
- Richard J. Butler
- RJ Butler
- Roger B. J. Benson
- RW Sadleir
- S Jouve
- S Jouve
- SA Price
- SG Platt
- SG Platt
- SJ Arnold
- SJ Arnold
- SM Drymala
- SM Stanley
- SP Blomberg
- T Aureliano
- T Garland
- T Ingram
- T Stadler
- TF Hansen
- TF Hansen
- TF Hansen
- TL Stubbs
- TM Williams
- TS Marinho
- W Gearty
- W Langston
- WAI Calder
- Y Herrera
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Background: Little is known about the long-term patterns of body size evolution in Crocodylomorpha, the > 200-million-year-old group that includes living crocodylians and their extinct relatives. Extant crocodylians are mostly large-bodied (3–7 m) predators. However, extinct crocodylomorphs exhibit a wider range of phenotypes, and many of the earliest taxa were much smaller (
Results: Crocodylomorphs reached an early peak in body size disparity during the Late Jurassic, and underwent an essentially continual decline since then. A multi-peak Ornstein-Uhlenbeck model outperforms all other evolutionary models fitted to our data (including both uniform and non-uniform), indicating that the macroevolutionary dynamics of crocodylomorph body size are better described within the concept of an adaptive landscape, with most body size variation emerging after shifts to new macroevolutionary regimes (analogous to adaptive zones). We did not find support for a consistent evolutionary trend towards larger sizes among lineages (i.e., Cope’s rule), or strong correlations of body size with climate. Instead, the intermediate to large body sizes of some crocodylomorphs are better explained by group-specific adaptations. In particular, the evolution of a more aquatic lifestyle (especially marine) correlates with increases in average body size, though not without exceptions.
Conclusions: Shifts between macroevolutionary regimes provide a better explanation of crocodylomorph body size evolution on large phylogenetic and temporal scales, suggesting a central role for lineage-specific adaptations rather than climatic forcing. Shifts leading to larger body sizes occurred in most aquatic and semi-aquatic groups. This, combined with extinctions of groups occupying smaller body size regimes (particularly during the Late Cretaceous and Cenozoic), gave rise to the upward-shifted body size distribution of extant crocodylomorphs compared to their smaller-bodied terrestrial ancestors.</p
Histone H1 Subtypes Differentially Modulate Chromatin Condensation without Preventing ATP-Dependent Remodeling by SWI/SNF or NURF
- Author
- A Contreras
- A Gunjan
- A Hamiche
- A Hamiche
- A Lusser
- A Ramachandran
- A Rodriguez-Campos
- A Rodriguez-Campos
- A Routh
- AJ Varshavsky
- B Dorigo
- B Drabent
- B Drabent
- BK Rasheed
- CL Smith
- CL Woodcock
- CL Woodcock
- D Doenecke
- DA Hill
- Detlef Doenecke
- DF Corona
- DN Chadee
- DN Chadee
- DT Brown
- DT Brown
- E Bonte
- EM Berkowitz
- F Thoma
- F Thoma
- FA Goytisolo
- GJ Carter
- GP Vicent
- H Loborg
- H Saeki
- H Takata
- H Talasz
- H Wang
- HC Huang
- I Ponte
- J Allan
- J Allan
- J Ausio
- J Dubochet
- J Zlatanova
- Jaime Clausell
- JD Maman
- JL Workman
- JM Hall
- JO Thomas
- JP Th'ng
- JR Khadake
- JR Wisniewski
- K Franke
- K Lee
- K Luger
- K Ura
- LM Carruthers
- LR Bucci
- LW Liao
- M Bruno
- M Higurashi
- M Orrego
- M Sancho
- M Tanaka
- M Zofall
- MH Parseghian
- MH Parseghian
- Miguel Beato
- MM Duggan
- N Happel
- N Happel
- Nicole Happel
- P Venditti
- PB Becker
- PB Becker
- PD Varga-Weisz
- PH Draves
- PJ Butler
- PJ Horn
- PJ Robinson
- PM Schwarz
- PM Schwarz
- R Koop
- R Sandaltzopoulos
- Rodolfo Aramayo
- RW Lennox
- RW Lennox
- RW Lennox
- S Cano
- S Khochbin
- S Panyim
- S Pennings
- S Stoldt
- SC Elgin
- SH Leuba
- T Schalch
- TA Blank
- TJ Maresca
- Tracy K. Hale
- V Dominguez
- V Ramakrishnan
- VA Huynh
- VK Maier
- VK Maier
- W Albig
- W Keller
- Y Fan
- Y Fan
- YB Zhou
- Publication venue
- Public Library of Science
- Publication date
- Field of study
Although ubiquitously present in chromatin, the function of the linker histone subtypes is partly unknown and contradictory studies on their properties have been published. To explore whether the various H1 subtypes have a differential role in the organization and dynamics of chromatin we have incorporated all of the somatic human H1 subtypes into minichromosomes and compared their influence on nucleosome spacing, chromatin compaction and ATP-dependent remodeling. H1 subtypes exhibit different affinities for chromatin and different abilities to promote chromatin condensation, as studied with the Atomic Force Microscope. According to this criterion, H1 subtypes can be classified as weak condensers (H1.1 and H1.2), intermediate condensers (H1.3) and strong condensers (H1.0, H1.4, H1.5 and H1x). The variable C-terminal domain is required for nucleosome spacing by H1.4 and is likely responsible for the chromatin condensation properties of the various subtypes, as shown using chimeras between H1.4 and H1.2. In contrast to previous reports with isolated nucleosomes or linear nucleosomal arrays, linker histones at a ratio of one per nucleosome do not preclude remodeling of minichromosomes by yeast SWI/SNF or Drosophila NURF. We hypothesize that the linker histone subtypes are differential organizers of chromatin, rather than general repressors
Precise determination of the mass of the Higgs boson and tests of compatibility of its couplings with the standard model predictions using proton collisions at 7 and 8 TeV
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- Abbaneo D
- Abbiendi G
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- Abdullin S
- Abdulsalam A
- Acosta D
- Acosta JG
- Adair A
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- Aldaya Martin M
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- Aleksandrov A
- Alexander J
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- Alverson G
- Alves GA
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- Amsler C
- Anagnostou G
- Anderson I
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- Andreev V
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- Apollinari G
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- Asawatangtrakuldee C
- Asin I
- Askew A
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- Azhgirey I
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- Zeuner WD
- Zevi Della Porta G
- Zeyrek M
- Zhang F
- Zhang J
- Zhang L
- Zhokin A
- Zhu RY
- Zhukov V
- Zhukova V
- Zorbilmez C
- Zotto P
- Zou W
- Zsigmond AJ
- Zucchetta A
- Zumerle G
- Zuranski A
- Zvada M
- Publication venue
- Publication date
- 01/01/2014
- Field of study
Peer reviewe
- …