Aceclofenac induced morbilliform eruptions: a case report

Maculopapular or morbilliform eruptions may be the most common of all cutaneous drug reactions. Antimicrobials, NSAIDS, barbiturates, anticonvulsants, oral hypoglycemics etc. have been commonly implicated in these adverse reactions (ADR). Here, authors are presenting a case of a 38-year-old female with morbilliform eruptions due to aceclofenac for the treatment of joint pain. The patient was treated with antihistaminics, steroids, antimicrobials and local application of GV paint. She was discharged after eleven days with good recovery

The impact of motivation on employees productivity in the retail sector: the mediating effect of compensation benefits

All companies aspire to compete against their rivals, retain a strategic edge in the industry, gain the largest market share and be inspired to bring out their utmost to achieve their desired goals at work. Few businesses think they will gain growth and wealth by important assets for their workers. Unfortunately, most companies appear to exploit the dismissal of their workers and talented applicants. Recognizing the critical position of workers appears to have a major effect on operational performance as most companies aim to maintain staff by empowering and enhancing the working standards of their employees. Therefore, it is necessary to enforce certain techniques to retain high quality and ensure performance and efficiency. The research examined the influence of organizational participation and encouragement in banks' work results. A study of 100 participants was tested, and findings were evaluated using the chi-square analysis. The findings revealed a substantial level below 5% which indicates that the study variables are closely linked. The quantitative approach and qualitative framework have been used to analyze their perception of the effects of job retention on the success of workers. Approach a single case study for various branches by implementing a similar case study and addressing a larger number of samples. This allows the researcher to remove the survey challenge and hold evidence from a larger community with a deeper comprehension of the idea of encouragement and how it influences workers' output

The Multiple Causes of Obesity

Obesity is known to cause physical and metabolic diseases. It is often assumed by people (including the healthcare workers) that the person with obesity lacks self-control in matters of diet and physical exercise, and is therefore responsible for his or her weight. Persons with obesity have to face sarcasm, barbs, and discrimination due to their condition. They often have difficulty in getting jobs or have to accept lower than standard pay for their work. Although weight gain requires calorie intake in excess of calorie expenditure, it is sometimes not easy for the person to restrict calories due to the underlying causes of obesity. The body resists losing weight, and attempts to hoard calories by reducing the metabolic rate. In this chapter we have explained and classified the causes of obesity into endogenous and exogenous. The endogenous causes include genetic and epigenetic causes, maternal factors, and hormonal causes, while exogenous causes include obesogenic environment, lifestyle, and weight-gain promoting medicines. It must be realized that losing weight and keeping it off is not easy for a person with obesity

High-Resolution Sonography: A New Technique to Detect Nerve Damage in Leprosy

Mycobacterium leprae, which causes leprosy, infects peripheral nerves resulting in functional impairment, ulcer formation and stigmatizing deformities. Early diagnosis of nerve involvement is important to avoid nerve related complications. We used non-invasive, high-resolution sonography (US) and color Doppler (CD) imaging to study the ulnar (UN), median (MN), lateral popliteal (LP) and posterior tibial (PT) nerves in 20 leprosy patients and compared 30 healthy Indian controls. The nerves were significantly thicker in the patients (p<0.0001 for each nerve). One of the key signs of leprosy is the presence of enlarged nerves. The kappa for clinical palpation and nerve enlargement by sonography was 0.30 for all examined nerves. Increased neural vascularity, the sign of inflammation was observed in 26% (39/152) of nerves by CD imaging. Increased CD was observed in multiple nerves in 3 of 4 patients with type 2 reaction. Significant correlation was observed between clinical parameters of grade of thickening, sensory loss and muscle weakness and US abnormalities of nerve echotexture, endoneural flow and cross-sectional area (p<0.001). We conclude that sonography is a better diagnostic tool to predict nerve damage as compared to clinical assessment. Nerve damage was sonographically more extensive and was observed in nerves considered clinically normal

Measurement of the top quark forward-backward production asymmetry and the anomalous chromoelectric and chromomagnetic moments in pp collisions at √s = 13 TeV

Abstract The parton-level top quark (t) forward-backward asymmetry and the anomalous chromoelectric (d̂ t) and chromomagnetic (μ̂ t) moments have been measured using LHC pp collisions at a center-of-mass energy of 13 TeV, collected in the CMS detector in a data sample corresponding to an integrated luminosity of 35.9 fb−1. The linearized variable AFB(1) is used to approximate the asymmetry. Candidate t t ¯ events decaying to a muon or electron and jets in final states with low and high Lorentz boosts are selected and reconstructed using a fit of the kinematic distributions of the decay products to those expected for t t ¯ final states. The values found for the parameters are AFB(1)=0.048−0.087+0.095(stat)−0.029+0.020(syst),μ̂t=−0.024−0.009+0.013(stat)−0.011+0.016(syst), and a limit is placed on the magnitude of | d̂ t| &lt; 0.03 at 95% confidence level. [Figure not available: see fulltext.

Measurement of t(t)over-bar normalised multi-differential cross sections in pp collisions at root s=13 TeV, and simultaneous determination of the strong coupling strength, top quark pole mass, and parton distribution functions

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An embedding technique to determine ττ backgrounds in proton-proton collision data

An embedding technique is presented to estimate standard model tau tau backgrounds from data with minimal simulation input. In the data, the muons are removed from reconstructed mu mu events and replaced with simulated tau leptons with the same kinematic properties. In this way, a set of hybrid events is obtained that does not rely on simulation except for the decay of the tau leptons. The challenges in describing the underlying event or the production of associated jets in the simulation are avoided. The technique described in this paper was developed for CMS. Its validation and the inherent uncertainties are also discussed. The demonstration of the performance of the technique is based on a sample of proton-proton collisions collected by CMS in 2017 at root s = 13 TeV corresponding to an integrated luminosity of 41.5 fb(-1).Peer reviewe

MUSiC : a model-unspecific search for new physics in proton-proton collisions at root s=13TeV

Results of the Model Unspecific Search in CMS (MUSiC), using proton-proton collision data recorded at the LHC at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1), are presented. The MUSiC analysis searches for anomalies that could be signatures of physics beyond the standard model. The analysis is based on the comparison of observed data with the standard model prediction, as determined from simulation, in several hundred final states and multiple kinematic distributions. Events containing at least one electron or muon are classified based on their final state topology, and an automated search algorithm surveys the observed data for deviations from the prediction. The sensitivity of the search is validated using multiple methods. No significant deviations from the predictions have been observed. For a wide range of final state topologies, agreement is found between the data and the standard model simulation. This analysis complements dedicated search analyses by significantly expanding the range of final states covered using a model independent approach with the largest data set to date to probe phase space regions beyond the reach of previous general searches.Peer reviewe