280 research outputs found
Thermal Radiation from Nucleons and Mesons
Thermal photon emission rates due to meson-nucleon interactions have been
evaluated. An exhaustive set of reactions involving p(\bar p), n(\bar n), rho,
omega, a_1, pi and eta is seen to provide a sizeable contribution to the
emission rate from hot hadronic matter. Contributions from baryonic resonances
are found to be negligibly small
Two-Boson Exchange Physics: A Brief Review
Current status of the two-boson exchange contributions to elastic
electron-proton scattering, both for parity conserving and parity-violating, is
briefly reviewed. How the discrepancy in the extraction of elastic nucleon form
factors between unpolarized Rosenbluth and polarization transfer experiments
can be understood, in large part, by the two-photon exchange corrections is
discussed. We also illustrate how the measurement of the ratio between
positron-proton and electron-proton scattering can be used to differentiate
different models of two-photon exchange. For the parity-violating
electron-proton scattering, the interest is on how the two-boson exchange
(TBE), \gamma Z-exchange in particular, could affect the extraction of the
long-sought strangeness form factors. Various calculations all indicate that
the magnitudes of effect of TBE on the extraction of strangeness form factors
is small, though can be large percentage-wise in certain kinematics.Comment: 6 pages, 5 figures, prepared for Proceedings of the fifth
Asia-Pacific Conference on Few-Body Problems in Physics (APFB2011), Seoul,
Korea, August 22-26, 2011, to appear in Few-Body Systems, November 201
Development of an economic wireless human motion analysis device for quantitative assessment of human body joint
In recent years, the study of human body dynamics has been attracting a significant amount of attention. Currently there are many camera or active sensor based motion analysis systems available on the market. They have been extensively adopted and used by the film and animation or entertainment industries such as film and video game producers. More recently their potential in studying human dynamics / motion for medical purposes has been realised to the extent that they are now used to study full body human biomechanics in the form of gait analysis systems. Most orthopaedic surgeries are usually about joint repair or implants. According health line, revision surgery is usually due to infection, continued pain, joint stiffness, wear, instability, loosening. Apart from infection, the rest can be linked to the operation itself. Currently, surgical planning and placing implants is performed in a subjective manner, relying on the surgeon’s experience and instinct, current systems to help the surgeon to place implant are also bulky, expensive, slow and not user friendly. The aim of this project is to develop an economic and portable motion assessment system which involves a wireless inertial measurement unit (IMU) dedicated to study and assess body joints. Through the data collected from the IMU, the system is capable real time measurement of relative position and orientation of the human joint. Several tests were conducted to validate the data extracted from gyroscope and accelerometer of the IMU. The joint motion results analysed using the device was compared with the results analysed using commercial video motion analysis software and it shows good correlation. It is found that the gyroscope of the IMU under DMP sensor fusion algorithm and calibration capability is able to give the angular velocity with less than 5% error. This has led to a more accurate orientation data which gives 7% error in average bending angle
Special Libraries, April 1933
Volume 24, Issue 3https://scholarworks.sjsu.edu/sla_sl_1933/1002/thumbnail.jp
Designing a broad-spectrum integrative approach for cancer prevention and treatment
Targeted therapies and the consequent adoption of "personalized" oncology have achieved notablesuccesses in some cancers; however, significant problems remain with this approach. Many targetedtherapies are highly toxic, costs are extremely high, and most patients experience relapse after a fewdisease-free months. Relapses arise from genetic heterogeneity in tumors, which harbor therapy-resistantimmortalized cells that have adopted alternate and compensatory pathways (i.e., pathways that are notreliant upon the same mechanisms as those which have been targeted). To address these limitations, aninternational task force of 180 scientists was assembled to explore the concept of a low-toxicity "broad-spectrum" therapeutic approach that could simultaneously target many key pathways and mechanisms. Using cancer hallmark phenotypes and the tumor microenvironment to account for the various aspectsof relevant cancer biology, interdisciplinary teams reviewed each hallmark area and nominated a widerange of high-priority targets (74 in total) that could be modified to improve patient outcomes. For thesetargets, corresponding low-toxicity therapeutic approaches were then suggested, many of which werephytochemicals. Proposed actions on each target and all of the approaches were further reviewed forknown effects on other hallmark areas and the tumor microenvironment. Potential contrary or procar-cinogenic effects were found for 3.9% of the relationships between targets and hallmarks, and mixedevidence of complementary and contrary relationships was found for 7.1%. Approximately 67% of therelationships revealed potentially complementary effects, and the remainder had no known relationship. Among the approaches, 1.1% had contrary, 2.8% had mixed and 62.1% had complementary relationships. These results suggest that a broad-spectrum approach should be feasible from a safety standpoint. Thisnovel approach has potential to be relatively inexpensive, it should help us address stages and types ofcancer that lack conventional treatment, and it may reduce relapse risks. A proposed agenda for futureresearch is offered
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Epstein-Barr virus: clinical and epidemiological revisits and genetic basis of oncogenesis
Epstein-Barr virus (EBV) is classified as a member in the order herpesvirales, family herpesviridae, subfamily gammaherpesvirinae and the genus lymphocytovirus. The virus is an exclusively human pathogen and thus also termed as human herpesvirus 4 (HHV4). It was the first oncogenic virus recognized and has been incriminated in the causation of tumors of both lymphatic and epithelial nature. It was reported in some previous studies that 95% of the population worldwide are serologically positive to the virus. Clinically, EBV primary infection is almost silent, persisting as a life-long asymptomatic latent infection in B cells although it may be responsible for a transient clinical syndrome called infectious mononucleosis. Following reactivation of the virus from latency due to immunocompromised status, EBV was found to be associated with several tumors. EBV linked to oncogenesis as detected in lymphoid tumors such as Burkitt's lymphoma (BL), Hodgkin's disease (HD), post-transplant lymphoproliferative disorders (PTLD) and T-cell lymphomas (e.g. Peripheral T-cell lymphomas; PTCL and Anaplastic large cell lymphomas; ALCL). It is also linked to epithelial tumors such as nasopharyngeal carcinoma (NPC), gastric carcinomas and oral hairy leukoplakia (OHL). In vitro, EBV many studies have demonstrated its ability to transform B cells into lymphoblastoid cell lines (LCLs). Despite these malignancies showing different clinical and epidemiological patterns when studied, genetic studies have suggested that these EBV- associated transformations were characterized generally by low level of virus gene expression with only the latent virus proteins (LVPs) upregulated in both tumors and LCLs. In this review, we summarize some clinical and epidemiological features of EBV- associated tumors. We also discuss how EBV latent genes may lead to oncogenesis in the different clinical malignancie
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